STRINGSTRING
Tbx3 Tbx3 Wnt5a Wnt5a Acvr1b Acvr1b LOC106000559 LOC106000559 Axin2 Axin2 Isl2 Isl2 Kras Kras Tbx2 Tbx2 Pax6 Pax6 Fzd2 Fzd2 Dusp9 Dusp9 ENSDORP00000020585 ENSDORP00000020585 Axin1 Axin1 Pik3r1 Pik3r1 Sox3 Sox3 Fgfr4 Fgfr4 Wnt7a Wnt7a Fzd9 Fzd9 Rest Rest Jak2 Jak2 Pou5f2 Pou5f2 Pcgf6 Pcgf6 Fgf2 Fgf2 Wnt2b Wnt2b Fzd8 Fzd8 Smad2 Smad2 Tcf3 Tcf3 Bmi1 Bmi1 Apc2 Apc2 Nfil3 Nfil3 Wnt3 Wnt3 Mapk1 Mapk1 Fzd5 Fzd5 Fgfr2 Fgfr2 Pik3r3 Pik3r3 Apc Apc Esrrg Esrrg Isl1 Isl1 Pcgf2 Pcgf2 Wnt4 Wnt4 Wnt2 Wnt2 Lifr Lifr Myf5 Myf5 Hand1 Hand1 Id2 Id2 Wnt16 Wnt16 Mapk13 Mapk13 Acvr2a Acvr2a Fzd7 Fzd7 Kat6a Kat6a Jak1 Jak1 Acvr1 Acvr1 Jak3 Jak3 Zic2 Zic2 Pik3cd Pik3cd Smarcad1 Smarcad1 Csde1 Csde1 Kras-2 Kras-2 Nodal Nodal Pcgf1 Pcgf1 Bmp4 Bmp4 Wnt10b Wnt10b Acvr1c Acvr1c ENSDORP00000009467 ENSDORP00000009467 Bmpr1a Bmpr1a Fgfr3 Fgfr3 Dlx5 Dlx5 Pik3ca Pik3ca Pou5f1 Pou5f1 Hoxd1 Hoxd1 Bmpr2 Bmpr2 Smad4 Smad4 Pcgf3 Pcgf3 Id1 Id1 Onecut2 Onecut2 Acvr2b Acvr2b Meis1 Meis1 Smad1 Smad1 Hoxb1 Hoxb1 Wnt1 Wnt1 Sox2 Sox2 Wnt8a Wnt8a Inhbe Inhbe Lhx1 Lhx1 Setdb1 Setdb1 Wnt9b Wnt9b Pik3cb Pik3cb Hoxa1 Hoxa1 Id3 Id3 Fzd1 Fzd1 Akt1 Akt1 Wnt11 Wnt11 Wnt10a Wnt10a Wnt6 Wnt6 Fzd6 Fzd6 Wnt9a Wnt9a Dvl2 Dvl2 Tcf7 Tcf7 Skil Skil Dvl3 Dvl3 Smad5 Smad5 Igf1r Igf1r Mast3 Mast3 LOC106002055 LOC106002055 Mapk3 Mapk3 Meis2 Meis2 Prrx1 Prrx1 Smad9 Smad9 Lhx5 Lhx5 Mapk12 Mapk12 Inhba Inhba Hesx1 Hesx1 Il6st Il6st Map2k1 Map2k1 Map2k2 Map2k2 Inhbc Inhbc Wnt8b Wnt8b Igf1 Igf1 Bmpr1b Bmpr1b Grb2 Grb2 ENSDORP00000027720 ENSDORP00000027720 Akt3 Akt3 Akt2 Akt2 LOC106002438 LOC106002438 Inhbb Inhbb Lif Lif Pcgf5 Pcgf5 Myc Myc Onecut1 Onecut1 Hras Hras Zic3 Zic3 Zfhx3 Zfhx3 Id4 Id4 Fzd3 Fzd3 Mapk14 Mapk14 Stat3 Stat3 Otx1 Otx1 Insr Insr Fgfr1 Fgfr1 Wnt7b Wnt7b Gsk3b Gsk3b Smad3 Smad3 Fgfr3-2 Fgfr3-2 Fzd4 Fzd4 Nras Nras
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tbx3T-box transcription factor TBX3. (133 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
Acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (450 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Axin2Axin-2. (837 aa)
Isl2ISL LIM homeobox 2. (325 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Tbx2T-box transcription factor TBX2. (590 aa)
Pax6Paired box protein Pax-6 isoform X2. (561 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
Dusp9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
ENSDORP00000020585annotation not available (80 aa)
Axin1Axin-1. (868 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Sox3LOW QUALITY PROTEIN: transcription factor SOX-3. (369 aa)
Fgfr4Fibroblast growth factor receptor. (766 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
Fzd9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
RestRE1-silencing transcription factor isoform X2. (329 aa)
Jak2Tyrosine-protein kinase. (1037 aa)
Pou5f2POU domain protein. (329 aa)
Pcgf6Polycomb group RING finger protein 6. (318 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
Wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
Fzd8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (418 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Tcf3Transcription factor E2-alpha isoform X2. (655 aa)
Bmi1Polycomb complex protein BMI-1. (324 aa)
Apc2Adenomatous polyposis coli protein 2. (2138 aa)
Nfil3Nuclear factor interleukin-3-regulated protein. (456 aa)
Wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
Fgfr2Fibroblast growth factor receptor. (819 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
ApcAdenomatous polyposis coli protein isoform X2. (2842 aa)
EsrrgEstrogen-related receptor gamma. (458 aa)
Isl1Insulin gene enhancer protein ISL-1 isoform X1. (349 aa)
Pcgf2Polycomb group RING finger protein 2 isoform X2. (344 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LifrLeukemia inhibitory factor receptor isoform X2. (1088 aa)
Myf5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
Hand1Heart- and neural crest derivatives-expressed protein 1. (214 aa)
Id2DNA-binding protein inhibitor ID-2. (116 aa)
Wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
Mapk13Mitogen-activated protein kinase. (334 aa)
Acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Fzd7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
Kat6aHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (886 aa)
Jak1Tyrosine-protein kinase. (1155 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
Jak3Tyrosine-protein kinase JAK3. (999 aa)
Zic2Zinc finger protein ZIC 2. (454 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Smarcad1annotation not available (1024 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
NodalNodal homolog. (353 aa)
Pcgf1Polycomb group RING finger protein 1. (259 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
Acvr1cReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (363 aa)
ENSDORP00000009467annotation not available (260 aa)
Bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Fgfr3Fibroblast growth factor receptor 3. (47 aa)
Dlx5Homeobox protein DLX-5 isoform X1. (289 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Pou5f1POU domain protein. (360 aa)
Hoxd1Homeobox protein Hox-D1. (330 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (933 aa)
Smad4Mothers against decapentaplegic homolog. (528 aa)
Pcgf3Polycomb group RING finger protein 3. (241 aa)
Id1DNA-binding protein inhibitor ID-1. (183 aa)
Onecut2One cut domain family member. (421 aa)
Acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (303 aa)
Meis1Homeobox protein Meis1 isoform X2. (465 aa)
Smad1Mothers against decapentaplegic homolog. (465 aa)
Hoxb1Homeobox protein Hox-B1. (302 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Sox2Transcription factor SOX-2. (321 aa)
Wnt8aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
InhbeInhibin beta E chain. (350 aa)
Lhx1LIM/homeobox protein Lhx1. (406 aa)
Setdb1Histone-lysine N-methyltransferase SETDB1. (1287 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Hoxa1Homeobox protein Hox-A1 isoform X1. (338 aa)
Id3DNA-binding protein inhibitor ID-3. (119 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (656 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
Wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
Fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
Wnt9aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
Dvl2Segment polarity protein dishevelled homolog DVL-2 isoform X3. (736 aa)
Tcf7Transcription factor 7 isoform X10. (344 aa)
SkilSki-like protein. (674 aa)
Dvl3Segment polarity protein dishevelled homolog DVL-3. (716 aa)
Smad5Mothers against decapentaplegic homolog. (465 aa)
Igf1rTyrosine-protein kinase receptor. (923 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
LOC106002055Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (160 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Meis2Homeobox protein Meis2. (438 aa)
Prrx1Paired mesoderm homeobox protein 1. (132 aa)
Smad9Mothers against decapentaplegic homolog. (430 aa)
Lhx5LIM/homeobox protein Lhx5. (324 aa)
Mapk12Mitogen-activated protein kinase. (351 aa)
InhbaInhibin beta A chain. (133 aa)
Hesx1Homeobox expressed in ES cells 1. (185 aa)
Il6stInterleukin-6 receptor subunit beta. (828 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
InhbcInhibin beta C chain. (351 aa)
Wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Igf1Insulin-like growth factor I isoform X2. (130 aa)
Bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
ENSDORP00000027720annotation not available (121 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC106002438Interleukin-6 receptor subunit beta-like. (123 aa)
InhbbInhibin beta B chain. (659 aa)
LifLeukemia inhibitory factor. (202 aa)
Pcgf5Polycomb group RING finger protein 5 isoform X1. (256 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
Onecut1One cut domain family member. (416 aa)
HrasGTPase HRas isoform X1. (192 aa)
Zic3Zinc finger protein ZIC 3 isoform X1. (466 aa)
Zfhx3Zinc finger homeobox protein 3. (3365 aa)
Id4DNA-binding protein inhibitor ID-4. (161 aa)
Fzd3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Otx1Homeobox protein OTX1. (354 aa)
InsrTyrosine-protein kinase receptor. (1183 aa)
Fgfr1Fibroblast growth factor receptor. (822 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
Fgfr3-2Fibroblast growth factor receptor. (176 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (538 aa)
NrasGTPase NRas. (189 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.