STRINGSTRING
Ptpn11 Ptpn11 Zap70 Zap70 Pik3cb Pik3cb Shc3 Shc3 Ptk6 Ptk6 Mast3 Mast3 Bid Bid Prkcg Prkcg Ifngr1 Ifngr1 ENSDORP00000003548 ENSDORP00000003548 Shc1 Shc1 Mapk3 Mapk3 Tyrobp Tyrobp Sos1 Sos1 Vav3 Vav3 Csf2 Csf2 Shc2 Shc2 Map2k1 Map2k1 Map2k2 Map2k2 Ptpn6 Ptpn6 Syk Syk Fcer1g Fcer1g Grb2 Grb2 Tnfsf10 Tnfsf10 Klrk1 Klrk1 Ppp3ca Ppp3ca Sh2d1a Sh2d1a ENSDORP00000026390 ENSDORP00000026390 Ppp3cb Ppp3cb Cd48 Cd48 Hras Hras LOC105989056 LOC105989056 Cd247 Cd247 Ppp3cc Ppp3cc Nras Nras LOC106000559 LOC106000559 Ifngr2 Ifngr2 Sh3bp2 Sh3bp2 Kras Kras Nfatc1 Nfatc1 Sos2 Sos2 Vav1 Vav1 ENSDORP00000020304 ENSDORP00000020304 Pik3r1 Pik3r1 Casp3 Casp3 Nfatc2 Nfatc2 Araf Araf Ppp3r1 Ppp3r1 Hcst Hcst ENSDORP00000017709 ENSDORP00000017709 Braf Braf Mapk1 Mapk1 Pak1 Pak1 Pik3r3 Pik3r3 Plcg2 Plcg2 Lat Lat Prkcb Prkcb LOC105994230 LOC105994230 Raf1 Raf1 Rac1 Rac1 Tnf Tnf Pik3cd Pik3cd Plcg1 Plcg1 Treml4 Treml4 Vav2 Vav2 Faslg Faslg Csde1 Csde1 Kras-2 Kras-2 Shc4 Shc4 Cep152 Cep152 Prkca Prkca Ptk2b Ptk2b Itgal Itgal Prf1 Prf1 Pik3ca Pik3ca Rac2 Rac2 Fcgr4 Fcgr4 LOC105998506 LOC105998506
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Zap70Tyrosine-protein kinase. (618 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Shc3SHC-transforming protein 3. (598 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Ifngr1Interferon gamma receptor 1. (469 aa)
ENSDORP00000003548annotation not available (165 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
TyrobpTYRO protein tyrosine kinase-binding protein. (114 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (140 aa)
Shc2SHC-transforming protein 2. (513 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
SykTyrosine-protein kinase. (633 aa)
Fcer1gHigh affinity immunoglobulin epsilon receptor subunit gamma. (69 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Tnfsf10Tumor necrosis factor ligand superfamily member. (288 aa)
Klrk1NKG2-D type II integral membrane protein isoform X2. (123 aa)
Ppp3caSerine/threonine-protein phosphatase. (479 aa)
Sh2d1aSH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (126 aa)
ENSDORP00000026390annotation not available (153 aa)
Ppp3cbSerine/threonine-protein phosphatase. (492 aa)
Cd48CD48 antigen isoform X3. (215 aa)
HrasGTPase HRas isoform X1. (192 aa)
LOC105989056Tumor necrosis factor receptor superfamily member 23-like. (120 aa)
Cd247T-cell surface glycoprotein CD3 zeta chain isoform X1. (164 aa)
Ppp3ccSerine/threonine-protein phosphatase. (478 aa)
NrasGTPase NRas. (189 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Ifngr2Interferon gamma receptor 2. (297 aa)
Sh3bp2SH3 domain-binding protein 2 isoform X1. (580 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (690 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
Vav1Proto-oncogene vav. (845 aa)
ENSDORP00000020304annotation not available (160 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
Nfatc2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (728 aa)
ArafSerine/threonine-protein kinase A-Raf. (606 aa)
Ppp3r1Calcineurin subunit B type 1. (169 aa)
HcstHematopoietic cell signal transducer isoform X2. (80 aa)
ENSDORP00000017709annotation not available (94 aa)
BrafSerine/threonine-protein kinase B-raf. (705 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
LatLinker for activation of T-cells family member 1 isoform X1. (234 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
LOC105994230Leukocyte immunoglobulin-like receptor subfamily A member 6. (297 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (590 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Treml4Trem-like transcript 4 protein. (212 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (276 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Shc4SHC-transforming protein 4. (340 aa)
Cep152Centrosomal protein of 152 kDa. (655 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ItgalIntegrin alpha-L; Belongs to the integrin alpha chain family. (1150 aa)
Prf1Perforin-1. (554 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (184 aa)
Fcgr4Low affinity immunoglobulin gamma Fc region receptor III-A isoform X2. (243 aa)
LOC105998506Intercellular adhesion molecule 2-like. (110 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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