STRINGSTRING
Pdcd1 Pdcd1 Cd247 Cd247 Gsk3b Gsk3b Pak4-2 Pak4-2 Pak6 Pak6 Mapk14 Mapk14 Cd40lg Cd40lg Prkcq Prkcq Rasgrp1 Rasgrp1 Pak2 Pak2 Hras Hras Mapk8 Mapk8 Ppp3cb Ppp3cb Fos Fos Akt2 Akt2 Ppp3ca Ppp3ca Malt1 Malt1 Akt3 Akt3 Grb2 Grb2 Pik3cd Pik3cd ENSDORP00000011621 ENSDORP00000011621 Plcg1 Plcg1 Chuk Chuk Pdpk1 Pdpk1 Vav2 Vav2 Csde1 Csde1 Kras-2 Kras-2 Il10 Il10 Pak7 Pak7 Nfkbie Nfkbie Itk Itk Cblb Cblb Icos Icos Mapk10 Mapk10 Pik3ca Pik3ca Map2k7 Map2k7 Ctla4 Ctla4 Nfkb1 Nfkb1 Cdk4 Cdk4 Zap70 Zap70 Pak4 Pak4 Pik3cb Pik3cb Akt1 Akt1 Card11 Card11 Ptk6 Ptk6 Mast3 Mast3 Mapk9 Mapk9 Nck2 Nck2 Cd3d Cd3d Cd3e Cd3e Rhoc Rhoc Mapk3 Mapk3 Sos1 Sos1 Vav3 Vav3 Pak3 Pak3 Csf2 Csf2 Mapk12 Mapk12 Nfkbib Nfkbib Map2k1 Map2k1 Map2k2 Map2k2 Ptpn6 Ptpn6 Ikbkg Ikbkg Tnf Tnf Rela Rela Ikbkb Ikbkb Nfkbia Nfkbia Map3k7 Map3k7 Cd28 Cd28 Nck1 Nck1 Mapk13 Mapk13 Il2 Il2 Grap2 Grap2 Map3k14 Map3k14 Il5 Il5 Lat Lat Ptprc Ptprc Tec Tec Cd3g Cd3g Pik3r3 Pik3r3 Pak1 Pak1 Mapk1 Mapk1 Rhoa Rhoa LOC106001529 LOC106001529 Ppp3r1 Ppp3r1 Nfatc2 Nfatc2 Nfatc3 Nfatc3 Pik3r1 Pik3r1 Map3k8 Map3k8 Vav1 Vav1 Sos2 Sos2 Nfatc1 Nfatc1 Kras Kras LOC106000559 LOC106000559 Bcl10 Bcl10 Nras Nras Ppp3cc Ppp3cc ENSDORP00000022835 ENSDORP00000022835 LOC105989352 LOC105989352
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pdcd1Programmed cell death protein 1. (286 aa)
Cd247T-cell surface glycoprotein CD3 zeta chain isoform X1. (164 aa)
Gsk3bGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
Pak4-2Non-specific serine/threonine protein kinase. (110 aa)
Pak6Non-specific serine/threonine protein kinase. (668 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Cd40lgCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
PrkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
Rasgrp1RAS guanyl-releasing protein 1. (763 aa)
Pak2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (507 aa)
HrasGTPase HRas isoform X1. (192 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Ppp3cbSerine/threonine-protein phosphatase. (492 aa)
FosProto-oncogene c-Fos. (380 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Ppp3caSerine/threonine-protein phosphatase. (479 aa)
Malt1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (823 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ENSDORP00000011621annotation not available (186 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Il10Interleukin-10. (178 aa)
Pak7Non-specific serine/threonine protein kinase. (338 aa)
NfkbieNF-kappa-B inhibitor epsilon. (308 aa)
ItkTyrosine-protein kinase. (620 aa)
CblbE3 ubiquitin-protein ligase CBL-B isoform X2. (939 aa)
IcosInducible T-cell costimulator isoform X1. (202 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
Ctla4Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Zap70Tyrosine-protein kinase. (618 aa)
Pak4Non-specific serine/threonine protein kinase. (587 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Card11Caspase recruitment domain-containing protein 11 isoform X4. (1154 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
Nck2Cytoplasmic protein. (380 aa)
Cd3dT-cell surface glycoprotein CD3 delta chain. (167 aa)
Cd3eT-cell surface glycoprotein CD3 epsilon chain. (190 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Pak3Non-specific serine/threonine protein kinase. (559 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (140 aa)
Mapk12Mitogen-activated protein kinase. (351 aa)
NfkbibNF-kappa-B inhibitor beta. (344 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
Map3k7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (596 aa)
Cd28T-cell-specific surface glycoprotein CD28. (219 aa)
Nck1Cytoplasmic protein. (377 aa)
Mapk13Mitogen-activated protein kinase. (334 aa)
Il2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
Grap2GRB2-related adapter protein 2 isoform X2. (324 aa)
Map3k14Mitogen-activated protein kinase kinase kinase 14 isoform X1. (933 aa)
Il5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
LatLinker for activation of T-cells family member 1 isoform X1. (234 aa)
PtprcReceptor-type tyrosine-protein phosphatase C isoform X1. (1252 aa)
TecTyrosine-protein kinase. (631 aa)
Cd3gT-cell surface glycoprotein CD3 gamma chain. (180 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
RhoaTransforming protein RhoA. (193 aa)
LOC106001529Mitogen-activated protein kinase kinase kinase 7-like. (538 aa)
Ppp3r1Calcineurin subunit B type 1. (169 aa)
Nfatc2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (728 aa)
Nfatc3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1077 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Map3k8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
Vav1Proto-oncogene vav. (845 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (690 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Bcl10B-cell lymphoma/leukemia 10. (117 aa)
NrasGTPase NRas. (189 aa)
Ppp3ccSerine/threonine-protein phosphatase. (478 aa)
ENSDORP00000022835annotation not available (193 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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