STRINGSTRING
Arpc1b Arpc1b Akt2 Akt2 Scin Scin Arpc3 Arpc3 Plpp3 Plpp3 ENSDORP00000026390 ENSDORP00000026390 Sphk2 Sphk2 Was Was LOC105997620 LOC105997620 Golga2 Golga2 LOC105996454 LOC105996454 Arpc4 Arpc4 Arf6 Arf6 Vasp Vasp ENSDORP00000023223 ENSDORP00000023223 LOC105989352 LOC105989352 Pip5k1a Pip5k1a Dnm2 Dnm2 Pla2g4a Pla2g4a Plpp2 Plpp2 Crk Crk ENSDORP00000021938 ENSDORP00000021938 LOC106000559 LOC106000559 Ncf1 Ncf1 Arpc5l Arpc5l Crkl Crkl Rps6kb2 Rps6kb2 Pld1 Pld1 Vav1 Vav1 Arpc5 Arpc5 ENSDORP00000020304 ENSDORP00000020304 Limk1 Limk1 Pik3r1 Pik3r1 Sphk1 Sphk1 Prkcd Prkcd Pip5k1c Pip5k1c Pld2 Pld2 Amph Amph ENSDORP00000017709 ENSDORP00000017709 Asap3 Asap3 Mapk1 Mapk1 Pak1 Pak1 Marcksl1 Marcksl1 Pip5k1b Pip5k1b LOC105989882 LOC105989882 Myo10 Myo10 Pik3r3 Pik3r3 Fcgr1 Fcgr1 Ptprc Ptprc Arpc2 Arpc2 Arpc1a Arpc1a Plcg2 Plcg2 Limk2 Limk2 Lat Lat Prkcb Prkcb Gsn Gsn Inpp5d Inpp5d Rac1 Rac1 Asap2 Asap2 LOC105981182 LOC105981182 Pik3cd Pik3cd Plcg1 Plcg1 Asap1 Asap1 Vav2 Vav2 LOC106001479 LOC106001479 Inppl1 Inppl1 Ccdc125 Ccdc125 Prkce Prkce Prkca Prkca Cfl1 Cfl1 Gab2 Gab2 Wasf1 Wasf1 Pik3ca Pik3ca Rac2 Rac2 Fcgr4 Fcgr4 ENSDORP00000007707 ENSDORP00000007707 Wasf2 Wasf2 Bin1 Bin1 Plpp1 Plpp1 Pik3cb Pik3cb Cfl2 Cfl2 Akt1 Akt1 Pla2g4f Pla2g4f Pla2g4d Pla2g4d Mast3 Mast3 Prkcg Prkcg Dock1 Dock1 Mapk3 Mapk3 Wasf3 Wasf3 Pla2g6 Pla2g6 Vav3 Vav3 Pla2g4e Pla2g4e Map2k1 Map2k1 Lyn Lyn Syk Syk Akt3 Akt3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Arpc1bActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ScinAdseverin. (696 aa)
Arpc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (154 aa)
Plpp3Lipid phosphate phosphohydrolase 3. (312 aa)
ENSDORP00000026390annotation not available (153 aa)
Sphk2Sphingosine kinase 2. (619 aa)
Waswiskott-Aldrich syndrome protein. (503 aa)
LOC105997620Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (282 aa)
Golga2Golgin subfamily A member 2 isoform X1. (1031 aa)
LOC105996454Low affinity immunoglobulin gamma Fc region receptor II-like. (311 aa)
Arpc4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
Arf6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
VaspVasodilator-stimulated phosphoprotein isoform X2; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (379 aa)
ENSDORP00000023223annotation not available (74 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
Pip5k1aPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha. (569 aa)
Dnm2Dynamin-2 isoform X5; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
Pla2g4aPhospholipase A2. (750 aa)
Plpp2Lipid phosphate phosphohydrolase 2. (298 aa)
CrkAdapter molecule crk. (304 aa)
ENSDORP00000021938annotation not available (332 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Ncf1Neutrophil cytosol factor 1 isoform X4. (396 aa)
Arpc5lActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
CrklCrk-like protein. (303 aa)
Rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
Pld1Phospholipase. (968 aa)
Vav1Proto-oncogene vav. (845 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ENSDORP00000020304annotation not available (160 aa)
Limk1LIM domain kinase 1. (635 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Sphk1Sphingosine kinase 1. (372 aa)
PrkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
Pip5k1cLOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (976 aa)
Pld2Phospholipase. (934 aa)
AmphAmphiphysin. (639 aa)
ENSDORP00000017709annotation not available (94 aa)
Asap3arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3. (904 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
Marcksl1MARCKS-related protein. (200 aa)
Pip5k1bPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X3. (540 aa)
LOC105989882Actin-related protein 2/3 complex subunit 2 pseudogene. (295 aa)
Myo10Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2005 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Fcgr1High affinity immunoglobulin gamma Fc receptor I-like isoform X2. (387 aa)
PtprcReceptor-type tyrosine-protein phosphatase C isoform X1. (1252 aa)
Arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (209 aa)
Arpc1aActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (382 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Limk2LIM domain kinase 2 isoform X2. (617 aa)
LatLinker for activation of T-cells family member 1 isoform X1. (234 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
GsnGelsolin isoform X2. (568 aa)
Inpp5dPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1186 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Asap2arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2. (959 aa)
LOC105981182Phospholipase A2. (787 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Asap1arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1. (1148 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
LOC106001479Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (492 aa)
Inppl1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1240 aa)
Ccdc125Coiled-coil domain-containing protein 125. (484 aa)
PrkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (548 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (168 aa)
Gab2GRB2-associated-binding protein 2. (608 aa)
Wasf1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (184 aa)
Fcgr4Low affinity immunoglobulin gamma Fc region receptor III-A isoform X2. (243 aa)
ENSDORP00000007707annotation not available (165 aa)
Wasf2wiskott-Aldrich syndrome protein family member 2. (496 aa)
Bin1Myc box-dependent-interacting protein 1 isoform X5. (562 aa)
Plpp1Lipid phosphate phosphohydrolase 1 isoform X2. (285 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Cfl2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pla2g4fPhospholipase A2, group IVF. (843 aa)
Pla2g4dPhospholipase A2. (708 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Dock1Dedicator of cytokinesis protein 1 isoform X2; Belongs to the DOCK family. (1870 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Wasf3wiskott-Aldrich syndrome protein family member 3. (503 aa)
Pla2g685/88 kDa calcium-independent phospholipase A2. (802 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Pla2g4ePhospholipase A2. (866 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
LynTyrosine-protein kinase. (512 aa)
SykTyrosine-protein kinase. (633 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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