STRINGSTRING
Tab3 Tab3 Mmp14 Mmp14 Tab2 Tab2 Map2k1 Map2k1 Map3k5 Map3k5 Mapk12 Mapk12 Csf2 Csf2 Tnfaip3 Tnfaip3 Creb3l2 Creb3l2 Ptgs2 Ptgs2 Creb3l3 Creb3l3 Mapk3 Mapk3 Atf2 Atf2 Irf1 Irf1 Mapk9 Mapk9 Traf2 Traf2 Atf6b Atf6b Mast3 Mast3 Atf4 Atf4 Jag1 Jag1 Akt1 Akt1 Pik3cb Pik3cb Rps6ka5 Rps6ka5 Nfkb1 Nfkb1 Ccdc88b Ccdc88b Ccl5 Ccl5 Rfwd3 Rfwd3 Vegfd Vegfd Bcl3 Bcl3 Ceacam16 Ceacam16 Map2k7 Map2k7 Pik3ca Pik3ca Il18r1 Il18r1 Il1b Il1b Mapk10 Mapk10 Birc2 Birc2 Ripk1 Ripk1 Creb5 Creb5 Dnm1l Dnm1l Creb3l4 Creb3l4 Chuk Chuk Pik3cd Pik3cd Map2k3 Map2k3 Tnf Tnf Creb1 Creb1 Rela Rela Ikbkb Ikbkb Nfkbia Nfkbia Map3k7 Map3k7 Traf3 Traf3 Il15 Il15 Casp7 Casp7 Mapk13 Mapk13 Cx3cl1 Cx3cl1 Mmp10 Mmp10 Mmp3 Mmp3 Tradd Tradd Csf1 Csf1 Map3k14 Map3k14 LOC105988529 LOC105988529 Traf1 Traf1 Pik3r3 Pik3r3 Mapk1 Mapk1 Creb3 Creb3 Vegfc Vegfc LOC106001529 LOC106001529 Itch Itch Casp3 Casp3 Nod2 Nod2 Pik3r1 Pik3r1 Map3k8 Map3k8 Vcam1 Vcam1 Ccl20 Ccl20 LOC106000559 LOC106000559 Tab1 Tab1 Traf5 Traf5 Dab2ip Dab2ip LOC105990588 LOC105990588 Mapk14 Mapk14 Edn1 Edn1 Mapk8 Mapk8 Lta Lta Creb3l1 Creb3l1 Lif Lif Fos Fos Rps6ka4 Rps6ka4 Akt2 Akt2 Bag4 Bag4 Map2k6 Map2k6 Akt3 Akt3 Ikbkg Ikbkg Socs3 Socs3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tab3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (716 aa)
Mmp14Matrix metalloproteinase-14. (584 aa)
Tab2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5. (144 aa)
Mapk12Mitogen-activated protein kinase. (351 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (140 aa)
Tnfaip3Tumor necrosis factor alpha-induced protein 3. (329 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3. (464 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (507 aa)
Irf1Interferon regulatory factor. (132 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
Traf2TNF receptor-associated factor. (484 aa)
Atf6bCyclic AMP-dependent transcription factor ATF-6 beta. (604 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (345 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Rps6ka5Ribosomal protein S6 kinase. (768 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Ccdc88bCoiled-coil domain-containing protein 88B isoform X2. (1432 aa)
Ccl5C-C motif chemokine. (91 aa)
Rfwd3E3 ubiquitin-protein ligase RFWD3. (645 aa)
VegfdVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (351 aa)
Bcl3B-cell lymphoma 3 protein. (430 aa)
Ceacam16Carcinoembryonic antigen-related cell adhesion molecule 16. (427 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Il18r1Interleukin-18 receptor 1 isoform X2. (531 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (573 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (662 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
Dnm1lDynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (727 aa)
Creb3l4Cyclic AMP-responsive element-binding protein 3-like protein 4. (378 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Map2k3Dual specificity mitogen-activated protein kinase kinase 3. (202 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
Map3k7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (596 aa)
Traf3TNF receptor-associated factor. (549 aa)
Il15Interleukin; Belongs to the IL-15/IL-21 family. (175 aa)
Casp7Caspase-7; Belongs to the peptidase C14A family. (305 aa)
Mapk13Mitogen-activated protein kinase. (334 aa)
Cx3cl1Fractalkine. (385 aa)
Mmp10Stromelysin-2. (479 aa)
Mmp3Stromelysin-1-like. (474 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein. (309 aa)
Csf1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
Map3k14Mitogen-activated protein kinase kinase kinase 14 isoform X1. (933 aa)
LOC105988529C-X-C motif chemokine. (101 aa)
Traf1TNF receptor-associated factor. (408 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (372 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
LOC106001529Mitogen-activated protein kinase kinase kinase 7-like. (538 aa)
ItchE3 ubiquitin-protein ligase. (857 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1012 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Map3k8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
Vcam1Vascular cell adhesion protein 1. (739 aa)
Ccl20C-C motif chemokine. (102 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Tab1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (460 aa)
Traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
Dab2ipDisabled homolog 2-interacting protein isoform X1. (1166 aa)
LOC105990588Serine/threonine-protein phosphatase PGAM5, mitochondrial-like. (140 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Edn1Endothelin-1-like isoform X1. (202 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
LtaLymphotoxin-alpha; Belongs to the tumor necrosis factor family. (266 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (524 aa)
LifLeukemia inhibitory factor. (202 aa)
FosProto-oncogene c-Fos. (380 aa)
Rps6ka4Ribosomal protein S6 kinase alpha-4. (710 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Bag4BAG family molecular chaperone regulator 4. (456 aa)
Map2k6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
Socs3Suppressor of cytokine signaling 3. (228 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.