STRINGSTRING
Rhoc Rhoc Myl9 Myl9 Cldn8 Cldn8 Arhgap35 Arhgap35 Cldn15 Cldn15 Mapk12 Mapk12 Vav3 Vav3 Actrt2 Actrt2 Prkcg Prkcg Mast3 Mast3 Arhgap5 Arhgap5 Cldn7 Cldn7 Rapgef4 Rapgef4 Cldn6 Cldn6 Pik3cb Pik3cb Gnai2 Gnai2 Itgb1 Itgb1 Rock2 Rock2 Myl10 Myl10 Cldn16 Cldn16 Ptpn11 Ptpn11 F11r F11r Actl7b Actl7b Actl7a Actl7a Rac2 Rac2 Pik3ca Pik3ca Ctnna3 Ctnna3 Itgal Itgal Ctnna1 Ctnna1 Rock1 Rock1 Ptk2b Ptk2b Prkca Prkca Cd99l2 Cd99l2 Itk Itk Cldn19 Cldn19 Cldn10 Cldn10 Rap1a Rap1a Vav2 Vav2 Plcg1 Plcg1 ENSDORP00000011621 ENSDORP00000011621 Pik3cd Pik3cd Sipa1 Sipa1 Cybb Cybb Jam3 Jam3 Ncf4 Ncf4 Vcl Vcl Rassf5 Rassf5 Mmp2 Mmp2 Rac1 Rac1 Mapk13 Mapk13 Gnai3 Gnai3 Jam2 Jam2 Gabpa Gabpa Ezr Ezr Cldn11 Cldn11 Actn1 Actn1 Prkcb Prkcb Plcg2 Plcg2 Ctnna2 Ctnna2 Rapgef3 Rapgef3 Msn Msn Pik3r3 Pik3r3 Cxcr4 Cxcr4 Noxa1 Noxa1 Gnai1 Gnai1 Lpxn Lpxn Ctnnd1 Ctnnd1 Rhoa Rhoa Afdn Afdn Cldn18 Cldn18 Rap1b Rap1b Itga4 Itga4 Cyba Cyba ENSDORP00000019192 ENSDORP00000019192 Cxcl12 Cxcl12 Ptk2 Ptk2 Cldn1 Cldn1 LOC105993816 LOC105993816 Pik3r1 Pik3r1 Cldn3 Cldn3 Mylpf Mylpf Vcam1 Vcam1 ENSDORP00000020585 ENSDORP00000020585 Vav1 Vav1 Itgam Itgam Ncf1 Ncf1 Thy1 Thy1 Txk Txk LOC106000559 LOC106000559 Cldn17 Cldn17 Actb Actb Cldn14 Cldn14 ENSDORP00000022835 ENSDORP00000022835 LOC105989352 LOC105989352 Cldn4 Cldn4 ENSDORP00000023306 ENSDORP00000023306 Cldn5 Cldn5 Pxn Pxn Vasp Vasp Myl2 Myl2 Cldn23 Cldn23 Mapk14 Mapk14 Gm49909 Gm49909 Pecam1 Pecam1 Ocln Ocln Ncf2 Ncf2 ENSDORP00000026363 ENSDORP00000026363 Esam Esam Bcar1 Bcar1 Rhoh Rhoh Actl11 Actl11 Cldn9 Cldn9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RhocRho-related GTP-binding protein RhoC. (193 aa)
Myl9Myosin regulatory light polypeptide 9. (172 aa)
Cldn8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
Arhgap35Rho GTPase-activating protein 35. (1500 aa)
Cldn15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa)
Mapk12Mitogen-activated protein kinase. (351 aa)
Vav3Guanine nucleotide exchange factor VAV3. (847 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Arhgap5Rho GTPase-activating protein 5 isoform X1. (1503 aa)
Cldn7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
Rapgef4Rap guanine nucleotide exchange factor 4 isoform X1. (838 aa)
Cldn6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Rock2Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1114 aa)
Myl10Myosin regulatory light chain 10 isoform X1. (131 aa)
Cldn16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (289 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
F11rJunctional adhesion molecule A. (293 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (418 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (439 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (184 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Ctnna3Catenin alpha-3. (896 aa)
ItgalIntegrin alpha-L; Belongs to the integrin alpha chain family. (1150 aa)
Ctnna1LOW QUALITY PROTEIN: catenin alpha-1. (896 aa)
Rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Cd99l2CD99 antigen-like protein 2. (221 aa)
ItkTyrosine-protein kinase. (620 aa)
Cldn19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
Cldn10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
Rap1aRas-related protein Rap-1A. (178 aa)
Vav2Guanine nucleotide exchange factor VAV2. (766 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
ENSDORP00000011621annotation not available (186 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Sipa1Signal-induced proliferation-associated protein 1. (896 aa)
CybbCytochrome b-245 heavy chain. (570 aa)
Jam3LOW QUALITY PROTEIN: junctional adhesion molecule C. (310 aa)
Ncf4Neutrophil cytosol factor 4. (341 aa)
VclVinculin isoform X2. (1135 aa)
Rassf5Ras association domain-containing protein 5. (313 aa)
Mmp272 kDa type IV collagenase. (126 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Mapk13Mitogen-activated protein kinase. (334 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Jam2Junctional adhesion molecule B isoform X1. (298 aa)
GabpaGA-binding protein alpha chain isoform X1. (454 aa)
EzrEzrin isoform X1. (583 aa)
Cldn11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
Actn1Alpha-actinin-1. (848 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
Plcg2Phosphoinositide phospholipase C. (1065 aa)
Ctnna2Catenin alpha-2 isoform X1. (954 aa)
Rapgef3Rap guanine nucleotide exchange factor 3. (216 aa)
MsnMoesin. (583 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (357 aa)
Noxa1NADPH oxidase activator 1 isoform X1. (418 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LpxnLeupaxin; Belongs to the paxillin family. (386 aa)
Ctnnd1Catenin delta-1 isoform X1. (964 aa)
RhoaTransforming protein RhoA. (193 aa)
AfdnAfadin isoform X8. (1812 aa)
Cldn18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (264 aa)
Rap1bRas-related protein Rap-1b. (184 aa)
Itga4Integrin alpha-4; Belongs to the integrin alpha chain family. (1032 aa)
CybaCytochrome b-245 light chain. (176 aa)
ENSDORP00000019192annotation not available (133 aa)
Cxcl12Stromal cell-derived factor 1 isoform X2; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
Cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LOC105993816Myosin regulatory light polypeptide 9. (172 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Cldn3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
MylpfMyosin regulatory light chain 2, skeletal muscle isoform. (169 aa)
Vcam1Vascular cell adhesion protein 1. (739 aa)
ENSDORP00000020585annotation not available (80 aa)
Vav1Proto-oncogene vav. (845 aa)
ItgamIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1143 aa)
Ncf1Neutrophil cytosol factor 1 isoform X4. (396 aa)
Thy1Thy-1 membrane glycoprotein. (161 aa)
TxkTyrosine-protein kinase. (527 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Cldn17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa)
ActbActin, cytoplasmic 1. (375 aa)
Cldn14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa)
ENSDORP00000022835annotation not available (193 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
Cldn4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
ENSDORP00000023306annotation not available (141 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
PxnPaxillin isoform X3; Belongs to the paxillin family. (547 aa)
VaspVasodilator-stimulated phosphoprotein isoform X2; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (379 aa)
Myl2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (144 aa)
Cldn23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (294 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Gm49909Myosin regulatory light chain 12B. (172 aa)
Pecam1Platelet endothelial cell adhesion molecule. (715 aa)
OclnOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (523 aa)
Ncf2Neutrophil cytosol factor 2 isoform X1. (526 aa)
ENSDORP00000026363annotation not available (164 aa)
EsamEndothelial cell-selective adhesion molecule. (394 aa)
Bcar1Breast cancer anti-estrogen resistance protein 1 isoform X1. (931 aa)
RhohRho-related GTP-binding protein RhoH. (191 aa)
Actl11Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa)
Cldn9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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