STRINGSTRING
Gnb1 Gnb1 Creb3l1 Creb3l1 Akt3 Akt3 Gna11 Gna11 Gng10 Gng10 Akt2 Akt2 Chrna7 Chrna7 Fos Fos Adcy5 Adcy5 ENSDORP00000000566 ENSDORP00000000566 Adcy1 Adcy1 Map2k1 Map2k1 Itpr3 Itpr3 Plcb3 Plcb3 Gng7 Gng7 Bcl2 Bcl2 Creb3l2 Creb3l2 Creb3l3 Creb3l3 Mapk3 Mapk3 Prkcg Prkcg Kcnq3 Kcnq3 Gnb5 Gnb5 Mast3 Mast3 Ptk6 Ptk6 Kcnq1 Kcnq1 Pik3r6 Pik3r6 Kcnj12 Kcnj12 Atf4 Atf4 Cacna1d Cacna1d Adcy6 Adcy6 Gng8 Gng8 Camk2g Camk2g Ache Ache Akt1 Akt1 Pik3cb Pik3cb Gnai2 Gnai2 Adcy8 Adcy8 Chrm2 Chrm2 Adcy3 Adcy3 Gng4 Gng4 Chrm5 Chrm5 Arsi Arsi Pik3ca Pik3ca Gngt1 Gngt1 Kcnq4 Kcnq4 Kcnj6 Kcnj6 Prkca Prkca Creb5 Creb5 Adcy7 Adcy7 Pik3cg Pik3cg Adcy2 Adcy2 Kras-2 Kras-2 Csde1 Csde1 Creb3l4 Creb3l4 Chrm3 Chrm3 Kcnq5 Kcnq5 Adcy4 Adcy4 Pik3cd Pik3cd Creb1 Creb1 Kcnj14 Kcnj14 Gnai3 Gnai3 Prkaca Prkaca Plcb4 Plcb4 Gnb4 Gnb4 Cacna1s Cacna1s Prkcb Prkcb Camk2b Camk2b Gnb3 Gnb3 Slc18a3 Slc18a3 Gng11 Gng11 Pik3r3 Pik3r3 Gnao1 Gnao1 Mapk1 Mapk1 Slc5a7 Slc5a7 Gnai1 Gnai1 Adcy9 Adcy9 Chrm1 Chrm1 Creb3 Creb3 Ptrhd1 Ptrhd1 Camk2a Camk2a Kcnj2 Kcnj2 Kcnq2 Kcnq2 Chat Chat Gngt2 Gngt2 Jak2 Jak2 Chrnb2 Chrnb2 Kcnj4 Kcnj4 Prkacb Prkacb Cacna1b Cacna1b Chrna4 Chrna4 Pik3r1 Pik3r1 Cacna1c Cacna1c Chrna3 Chrna3 Plcb1 Plcb1 Camk2d Camk2d Kras Kras Gnaq Gnaq Gng12 Gng12 Kcnj3 Kcnj3 LOC106000559 LOC106000559 Cacna1a Cacna1a Pik3r5 Pik3r5 Chrnb4 Chrnb4 ENSDORP00000022081 ENSDORP00000022081 Chrna6 Chrna6 Nras Nras Chrm4 Chrm4 Gnb2 Gnb2 Itpr2 Itpr2 LOC105983978 LOC105983978 Gng5 Gng5 Gng2 Gng2 Gm5741 Gm5741 Gng3 Gng3 Gng13 Gng13 Cacna1f Cacna1f Plcb2 Plcb2 Itpr1 Itpr1 Hras Hras
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gnb1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (524 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (313 aa)
Gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Chrna7Neuronal acetylcholine receptor subunit alpha-7. (568 aa)
FosProto-oncogene c-Fos. (380 aa)
Adcy5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1186 aa)
ENSDORP00000000566annotation not available (65 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (937 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3 isoform X3. (2668 aa)
Plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
Gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3. (464 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Kcnq3Potassium voltage-gated channel subfamily KQT member 3; Belongs to the potassium channel family. (841 aa)
Gnb5Guanine nucleotide-binding protein subunit beta-5. (395 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
Kcnq1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (622 aa)
Pik3r6LOW QUALITY PROTEIN: phosphoinositide 3-kinase regulatory subunit 6. (682 aa)
Kcnj12ATP-sensitive inward rectifier potassium channel 12. (433 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (345 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2039 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Gng8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma. (515 aa)
AcheCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (614 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Chrm2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
Gng4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
Chrm5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (526 aa)
ArsiArylsulfatase I. (573 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Gngt1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
Kcnq4Potassium voltage-gated channel subfamily KQT member 4; Belongs to the potassium channel family. (591 aa)
Kcnj6G protein-activated inward rectifier potassium channel 2. (425 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
Pik3cgPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (264 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (854 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Creb3l4Cyclic AMP-responsive element-binding protein 3-like protein 4. (378 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
Kcnq5Potassium voltage-gated channel subfamily KQT member 5 isoform X1. (875 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Kcnj14ATP-sensitive inward rectifier potassium channel 14. (434 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
Gnb4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta. (644 aa)
Gnb3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
Slc18a3Vesicular acetylcholine transporter. (532 aa)
Gng11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Gnao1Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Slc5a7High affinity choline transporter 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1330 aa)
Chrm1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (372 aa)
Ptrhd1Putative peptidyl-tRNA hydrolase PTRHD1. (146 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (488 aa)
Kcnj2Inward rectifier potassium channel 2. (427 aa)
Kcnq2Potassium voltage-gated channel subfamily KQT member 2; Belongs to the potassium channel family. (838 aa)
ChatCholine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (739 aa)
Gngt2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Jak2Tyrosine-protein kinase. (1037 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2 isoform X1. (504 aa)
Kcnj4Inward rectifier potassium channel 4. (445 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Cacna1bVoltage-dependent N-type calcium channel subunit alpha-1B. (2037 aa)
Chrna4Neuronal acetylcholine receptor subunit alpha-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (625 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Chrna3Neuronal acetylcholine receptor subunit alpha-3. (542 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (533 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (333 aa)
Gng12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
Kcnj3G protein-activated inward rectifier potassium channel 1 isoform X1. (502 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Cacna1aVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (2254 aa)
Pik3r5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (872 aa)
Chrnb4Neuronal acetylcholine receptor subunit beta-4. (493 aa)
ENSDORP00000022081annotation not available (68 aa)
Chrna6Neuronal acetylcholine receptor subunit alpha-6. (494 aa)
NrasGTPase NRas. (189 aa)
Chrm4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
Gnb2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
LOC105983978Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Gng5G protein subunit gamma 5. (64 aa)
Gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
Gm5741Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
Gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Gng13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (247 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
HrasGTPase HRas isoform X1. (192 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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