STRINGSTRING
Grb2 Grb2 Adcy5 Adcy5 Adcy1 Adcy1 Ncoa1 Ncoa1 Map2k2 Map2k2 Map2k1 Map2k1 Itpr3 Itpr3 Shc2 Shc2 LOC106002313 LOC106002313 Krt20 Krt20 Krt23 Krt23 Plcb3 Plcb3 Gabbr2 Gabbr2 Bcl2 Bcl2 Oprm1 Oprm1 Ncoa3 Ncoa3 Sos1 Sos1 Creb3l2 Creb3l2 Creb3l3 Creb3l3 Mapk3 Mapk3 Shc1 Shc1 Atf2 Atf2 Atf6b Atf6b Mast3 Mast3 Gnas Gnas Atf4 Atf4 Adcy6 Adcy6 Shc3 Shc3 Hsp90b1 Hsp90b1 Hsp90aa1 Hsp90aa1 Pomc Pomc Akt1 Akt1 Pik3cb Pik3cb Gnai2 Gnai2 Adcy8 Adcy8 Krt25 Krt25 Krt26 Krt26 Krt27 Krt27 Krt28 Krt28 Krt10 Krt10 Krt32 Krt32 Krt36 Krt36 Krt13 Krt13 Krt15 Krt15 Krt19 Krt19 Adcy3 Adcy3 Fkbp5 Fkbp5 Kcnj5 Kcnj5 Krt39 Krt39 Tff1 Tff1 Pik3ca Pik3ca Calm2 Calm2 Kcnj6 Kcnj6 Ebag9 Ebag9 Creb5 Creb5 Esr1 Esr1 Adcy7 Adcy7 Cep152 Cep152 Shc4 Shc4 Ncoa2 Ncoa2 Adcy2 Adcy2 Hsp90ab1 Hsp90ab1 Kras-2 Kras-2 Csde1 Csde1 Creb3l4 Creb3l4 Krt18 Krt18 Adcy4 Adcy4 Pik3cd Pik3cd Hbegf Hbegf Creb1 Creb1 Egfr Egfr Mmp2 Mmp2 Ifitm10 Ifitm10 Ccdc170 Ccdc170 Gnai3 Gnai3 Prkaca Prkaca Plcb4 Plcb4 Hspa8 Hspa8 Krt24 Krt24 Krt17 Krt17 Krt40 Krt40 Calml3 Calml3 Hspa1l Hspa1l Sp1 Sp1 Pik3r3 Pik3r3 Tex21 Tex21 Mapk1 Mapk1 Gnai1 Gnai1 Adcy9 Adcy9 Calm1 Calm1 Creb3 Creb3 Hspa2 Hspa2 Ptrhd1 Ptrhd1 LOC105998610 LOC105998610 Calml4 Calml4 Prkcd Prkcd LOC105999841 LOC105999841 LOC106002471 LOC106002471 Gabbr1 Gabbr1 Hspa1b Hspa1b Krt35 Krt35 Prkacb Prkacb Fkbp4 Fkbp4 LOC106003009 LOC106003009 Pik3r1 Pik3r1 Kcnj9 Kcnj9 Plcb1 Plcb1 Sos2 Sos2 Kras Kras Rara Rara Calm3 Calm3 Krt16 Krt16 Kcnj3 Kcnj3 Tgfa Tgfa Krt14 Krt14 LOC106000559 LOC106000559 Nras Nras Itpr2 Itpr2 Nos3 Nos3 Plcb2 Plcb2 Itpr1 Itpr1 Gper1 Gper1 Hras Hras Creb3l1 Creb3l1 Gnao1 Gnao1 Fos Fos Akt2 Akt2 Esr2 Esr2 Krt9 Krt9 Akt3 Akt3 LOC106002482 LOC106002482 Krt42 Krt42
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Grb2Growth factor receptor-bound protein 2. (217 aa)
Adcy5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1186 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (937 aa)
Ncoa1Nuclear receptor coactivator. (1422 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3 isoform X3. (2668 aa)
Shc2SHC-transforming protein 2. (513 aa)
LOC106002313Keratin, type I cytoskeletal 12-like; Belongs to the intermediate filament family. (254 aa)
Krt20Keratin, type I cytoskeletal 20; Belongs to the intermediate filament family. (431 aa)
Krt23Keratin, type I cytoskeletal 23; Belongs to the intermediate filament family. (424 aa)
Plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
Gabbr2Gamma-aminobutyric acid type B receptor subunit 2. (954 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Oprm1Mu-type opioid receptor isoform X3; Belongs to the G-protein coupled receptor 1 family. (391 aa)
Ncoa3Nuclear receptor coactivator 3. (1412 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3. (464 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Shc1SHC-transforming protein 1 isoform X2. (473 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (507 aa)
Atf6bCyclic AMP-dependent transcription factor ATF-6 beta. (604 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (345 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Shc3SHC-transforming protein 3. (598 aa)
Hsp90b1Endoplasmin. (804 aa)
Hsp90aa1Heat shock protein HSP 90-alpha. (733 aa)
PomcPro-opiomelanocortin isoform X1. (261 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Krt25Keratin, type I cytoskeletal 25; Belongs to the intermediate filament family. (451 aa)
Krt26Keratin, type I cytoskeletal 26; Belongs to the intermediate filament family. (465 aa)
Krt27Keratin, type I cytoskeletal 27; Belongs to the intermediate filament family. (356 aa)
Krt28Keratin, type I cytoskeletal 28 isoform X1; Belongs to the intermediate filament family. (457 aa)
Krt10Keratin, type I cytoskeletal 10; Belongs to the intermediate filament family. (571 aa)
Krt32Keratin, type I cuticular Ha2; Belongs to the intermediate filament family. (453 aa)
Krt36Keratin, type I cuticular Ha6; Belongs to the intermediate filament family. (464 aa)
Krt13Keratin, type I cytoskeletal 13; Belongs to the intermediate filament family. (420 aa)
Krt15Keratin, type I cytoskeletal 15; Belongs to the intermediate filament family. (453 aa)
Krt19Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family. (399 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
Fkbp5Peptidylprolyl isomerase. (456 aa)
Kcnj5G protein-activated inward rectifier potassium channel 4. (416 aa)
Krt39Keratin, type I cytoskeletal 39; Belongs to the intermediate filament family. (465 aa)
Tff1Trefoil factor 1. (81 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (149 aa)
Kcnj6G protein-activated inward rectifier potassium channel 2. (425 aa)
Ebag9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
Esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
Cep152Centrosomal protein of 152 kDa. (655 aa)
Shc4SHC-transforming protein 4. (340 aa)
Ncoa2Nuclear receptor coactivator 2. (1435 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (854 aa)
Hsp90ab1Heat shock protein HSP 90-beta. (723 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Creb3l4Cyclic AMP-responsive element-binding protein 3-like protein 4. (378 aa)
Krt18Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (430 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
HbegfProheparin-binding EGF-like growth factor. (206 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
Mmp272 kDa type IV collagenase. (126 aa)
Ifitm10Interferon-induced transmembrane protein 10. (198 aa)
Ccdc170Coiled-coil domain-containing protein 170. (670 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
Hspa8Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (646 aa)
Krt24Keratin, type I cytoskeletal 24; Belongs to the intermediate filament family. (466 aa)
Krt17Keratin, type I cytoskeletal 17 isoform X2; Belongs to the intermediate filament family. (432 aa)
Krt40Keratin, type I cytoskeletal 40; Belongs to the intermediate filament family. (414 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Hspa1lHeat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa)
Sp1Transcription factor Sp1. (786 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Tex21Coiled-coil domain-containing protein 170-like. (575 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1330 aa)
Calm1Calmodulin 1. (149 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (372 aa)
Hspa2Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (634 aa)
Ptrhd1Putative peptidyl-tRNA hydrolase PTRHD1. (146 aa)
LOC105998610Interferon-induced transmembrane protein 1-like. (118 aa)
Calml4Calmodulin-like protein 4 isoform X1. (153 aa)
PrkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
LOC105999841Heat shock 70 kDa protein 1B; Belongs to the heat shock protein 70 family. (641 aa)
LOC106002471Keratin, type I cuticular Ha3-II-like; Belongs to the intermediate filament family. (305 aa)
Gabbr1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (961 aa)
Hspa1bHeat shock protein family A (Hsp70) member 1B. (635 aa)
Krt35Keratin, type I cuticular Ha5 isoform X1; Belongs to the intermediate filament family. (455 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Fkbp4Peptidylprolyl isomerase. (448 aa)
LOC106003009Keratin, type I cuticular Ha3-I; Belongs to the intermediate filament family. (423 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Kcnj9G protein-activated inward rectifier potassium channel 3. (393 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
RaraRetinoic acid receptor alpha. (343 aa)
Calm3Calmodulin 3. (149 aa)
Krt16Keratin, type I cytoskeletal 16 isoform X1; Belongs to the intermediate filament family. (499 aa)
Kcnj3G protein-activated inward rectifier potassium channel 1 isoform X1. (502 aa)
TgfaProtransforming growth factor alpha. (156 aa)
Krt14Keratin, type I cytoskeletal 14; Belongs to the intermediate filament family. (468 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
NrasGTPase NRas. (189 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1201 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
HrasGTPase HRas isoform X1. (192 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (524 aa)
Gnao1Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
FosProto-oncogene c-Fos. (380 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Esr2Estrogen receptor beta. (550 aa)
Krt9Keratin, type I cytoskeletal 9; Belongs to the intermediate filament family. (733 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC106002482Keratin, type I cuticular Ha1; Belongs to the intermediate filament family. (329 aa)
Krt42Keratin, type I cytoskeletal 42; Belongs to the intermediate filament family. (458 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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