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| | Wnt4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | Map2k1 | Dual specificity mitogen-activated protein kinase kinase 1. (375 aa) |
| | Tbc1d4 | TBC1 domain family member 4. (1285 aa) |
| | Plcb3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa) |
| | Atp1a1 | Sodium/potassium-transporting ATPase subunit alpha. (1024 aa) |
| | Bad | Bcl2-associated agonist of cell death isoform X1. (154 aa) |
| | Plcd1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1. (482 aa) |
| | Ncoa1 | Nuclear receptor coactivator. (1422 aa) |
| | Notch2 | Neurogenic locus notch homolog protein 2. (2322 aa) |
| | Map2k2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | Ncoa3 | Nuclear receptor coactivator 3. (1412 aa) |
| | Rcan2 | Calcipressin-2. (197 aa) |
| | Mapk3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa) |
| | Mtor | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa) |
| | Gata4 | Transcription factor GATA-4. (235 aa) |
| | Actrt2 | Actin-related protein T2; Belongs to the actin family. (377 aa) |
| | Prkcg | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | Mast3 | Microtubule associated serine/threonine kinase 3. (71 aa) |
| | Hif1a | Hypoxia-inducible factor 1-alpha. (246 aa) |
| | Med1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1546 aa) |
| | Med17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (621 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase. (188 aa) |
| | Pik3cb | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa) |
| | Rhebl1 | GTPase RhebL1. (176 aa) |
| | Atp1a3 | Sodium/potassium-transporting ATPase subunit alpha. (1035 aa) |
| | Kat2a | Histone acetyltransferase KAT2A isoform X1. (829 aa) |
| | Pfkl | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (770 aa) |
| | Mdm2 | E3 ubiquitin-protein ligase Mdm2. (446 aa) |
| | Med16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (829 aa) |
| | Atp1a2 | Sodium/potassium-transporting ATPase subunit alpha. (1046 aa) |
| | Myh4 | Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa) |
| | Myh2 | Myosin-2 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa) |
| | Actl7b | Actin-like protein 7B; Belongs to the actin family. (418 aa) |
| | Actl7a | Actin-like protein 7A; Belongs to the actin family. (439 aa) |
| | Pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | Myh15 | Myosin-15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1925 aa) |
| | Rxra | Retinoic acid receptor RXR-alpha. (457 aa) |
| | Med12 | Mediator of RNA polymerase II transcription subunit 12. (2183 aa) |
| | Prkca | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | Ep300 | Histone acetyltransferase p300. (2345 aa) |
| | Rheb | GTP-binding protein Rheb. (112 aa) |
| | Atp2a3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1009 aa) |
| | Esr1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa) |
| | Bmp4 | Bone morphogenetic protein 4. (409 aa) |
| | Atp1b4 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (359 aa) |
| | Pfkm | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa) |
| | Sin3a | Paired amphipathic helix protein Sin3a. (1274 aa) |
| | Ncoa2 | Nuclear receptor coactivator 2. (1435 aa) |
| | Stat1 | Signal transducer and activator of transcription. (765 aa) |
| | Kras-2 | GTPase KRas isoform X4. (189 aa) |
| | Csde1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | Plce1 | Phosphoinositide phospholipase C. (2291 aa) |
| | Slc2a1 | Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa) |
| | Pdpk1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa) |
| | Plcg1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa) |
| | Slc9a1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (802 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) |
| | Hdac3 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa) |
| | Ncor1 | Nuclear receptor corepressor 1. (1652 aa) |
| | Myh6 | Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1774 aa) |
| | Myh7 | Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa) |
| | Hdac2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | Slc16a10 | LOW QUALITY PROTEIN: monocarboxylate transporter 10. (315 aa) |
| | Myh3 | Myosin-3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa) |
| | Tsc2 | Tuberin isoform X1. (1809 aa) |
| | Rxrb | Retinoic acid receptor RXR-beta isoform X2. (526 aa) |
| | Rxrg | Retinoic acid receptor RXR-gamma isoform X1. (463 aa) |
| | Med27 | Mediator of RNA polymerase II transcription subunit 27 isoform X1. (311 aa) |
| | Ccdc170 | Coiled-coil domain-containing protein 170. (670 aa) |
| | Plcd3 | Phosphoinositide phospholipase C. (763 aa) |
| | Prkaca | cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa) |
| | Dio1 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (231 aa) |
| | Plcb4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa) |
| | Med24 | Mediator of RNA polymerase II transcription subunit 24 isoform X1. (1006 aa) |
| | Thra | Thyroid hormone receptor alpha. (491 aa) |
| | Foxo1 | Forkhead box protein O1. (537 aa) |
| | Atp1b1 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (293 aa) |
| | Prkcb | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa) |
| | Plcg2 | Phosphoinositide phospholipase C. (1065 aa) |
| | Itgb3 | Integrin beta; Belongs to the integrin beta chain family. (766 aa) |
| | Med12l | Mediator of RNA polymerase II transcription subunit 12-like protein. (2134 aa) |
| | Pfkp | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (793 aa) |
| | Ccnd1 | G1/S-specific cyclin-D1. (156 aa) |
| | Pik3r3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | ENSDORP00000016888 | annotation not available (180 aa) |
| | Hdac1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (477 aa) |
| | Atp2a1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1069 aa) |
| | Pfkfb2 | 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 isoform X1. (483 aa) |
| | Tex21 | Coiled-coil domain-containing protein 170-like. (575 aa) |
| | Mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | Med4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa) |
| | Plcd4 | Phosphoinositide phospholipase C. (736 aa) |
| | Atp2a2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (986 aa) |
| | Sin3b | Paired amphipathic helix protein Sin3b. (1013 aa) |
| | Itgav | Integrin alpha-V; Belongs to the integrin alpha chain family. (1047 aa) |
| | ENSDORP00000018543 | annotation not available (129 aa) |
| | Notch3 | Neurogenic locus notch homolog protein 3. (2133 aa) |
| | Pln | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | Prkacb | cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa) |
| | Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | ENSDORP00000020585 | annotation not available (80 aa) |
| | Plcb1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | Slco1c1 | Solute carrier organic anion transporter family member. (707 aa) |
| | Kras | Kirsten rat sarcoma viral oncogene homolog. (163 aa) |
| | LOC106000559 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa) |
| | Med13l | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2186 aa) |
| | Actb | Actin, cytoplasmic 1. (375 aa) |
| | Crebbp | CREB-binding protein. (2432 aa) |
| | Nras | GTPase NRas. (189 aa) |
| | Rcan3 | Calcipressin-3. (205 aa) |
| | Med14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1423 aa) |
| | ENSDORP00000022774 | annotation not available (389 aa) |
| | ENSDORP00000023022 | annotation not available (388 aa) |
| | Atp1b2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa) |
| | Gsk3b | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | ENSDORP00000023395 | annotation not available (201 aa) |
| | Trp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa) |
| | Gpsm3 | G-protein-signaling modulator 3. (165 aa) |
| | Slc16a2 | Monocarboxylate transporter 8. (547 aa) |
| | Thrb | Thyroid hormone receptor beta isoform X2. (461 aa) |
| | Rcan1 | Calcipressin-1. (197 aa) |
| | Myh1 | Myosin-1 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1942 aa) |
| | Med13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (611 aa) |
| | Med30 | Mediator of RNA polymerase II transcription subunit 30. (164 aa) |
| | Plcb2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa) |
| | Atp1b3 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (80 aa) |
| | Notch4 | Neurogenic locus notch homolog protein 4. (1953 aa) |
| | Hras | GTPase HRas isoform X1. (192 aa) |
| | Myc | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa) |
| | ENSDORP00000025871 | annotation not available (284 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Notch1 | Notch 1. (2304 aa) |
| | Actl11 | Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Myh8 | Myosin-8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa) |
