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Adcy5 Adcy5 Itpr3 Itpr3 Plcb3 Plcb3 Pde1b Pde1b Ren Ren Gnas Gnas Npr1 Npr1 Cacna1d Cacna1d Adcy6 Adcy6 Ptger4 Ptger4 Edn2 Edn2 Gnai2 Gnai2 Mindy4 Mindy4 Aqp1 Aqp1 Prkg2 Prkg2 Clca1 Clca1 Clca2 Clca2 Calm2 Calm2 Ptger2 Ptger2 Agt Agt Ctsb Ctsb Creb1 Creb1 Nppa Nppa Ednra Ednra LOC105991914 LOC105991914 Gnai3 Gnai3 Prkaca Prkaca Plcb4 Plcb4 Cacna1s Cacna1s LOC105991873 LOC105991873 Calml3 Calml3 Gucy1a2 Gucy1a2 Gucy1a1 Gucy1a1 Gnai1 Gnai1 Calm1 Calm1 Gucy1b2 Gucy1b2 Adcyap1 Adcyap1 Kcnj2 Kcnj2 Edn3 Edn3 Calml4 Calml4 Ppp3r1 Ppp3r1 Kcnma1 Kcnma1 Prkacb Prkacb Pde1a Pde1a Cacna1c Cacna1c Pde3b Pde3b Plcb1 Plcb1 Calm3 Calm3 Ace3 Ace3 Itpr2 Itpr2 Ppp3cc Ppp3cc Adcyap1r1 Adcyap1r1 Pde1c Pde1c Gucy1b1 Gucy1b1 Cacna1f Cacna1f Plcb2 Plcb2 Itpr1 Itpr1 Edn1 Edn1 Ppp3cb Ppp3cb Adora1 Adora1 Orai1 Orai1 Ppp3ca Ppp3ca Ace Ace Agtr1 Agtr1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Adcy5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1186 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3 isoform X3. (2668 aa)
Plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
Pde1bPhosphodiesterase. (535 aa)
RenRenin; Belongs to the peptidase A1 family. (403 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Npr1Guanylate cyclase. (1060 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2039 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Ptger4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (514 aa)
Edn2Endothelin-2 isoform X1. (178 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Mindy4Protein FAM188B. (721 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
Prkg2cGMP-dependent protein kinase. (733 aa)
Clca1Calcium-activated chloride channel regulator 1. (864 aa)
Clca2Calcium-activated chloride channel regulator 2. (943 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (149 aa)
Ptger2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (363 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
CtsbCathepsin B; Belongs to the peptidase C1 family. (339 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
NppaNatriuretic peptides A. (153 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
LOC105991914Calcium-activated chloride channel regulator 4-like. (921 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
LOC105991873Epithelial chloride channel protein-like. (904 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Gucy1a2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (678 aa)
Gucy1a1Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Calm1Calmodulin 1. (149 aa)
Gucy1b2Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (709 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
Kcnj2Inward rectifier potassium channel 2. (427 aa)
Edn3Endothelin-3. (206 aa)
Calml4Calmodulin-like protein 4 isoform X1. (153 aa)
Ppp3r1Calcineurin subunit B type 1. (169 aa)
Kcnma1Calcium-activated potassium channel subunit alpha-1. (1132 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Pde1aPhosphodiesterase. (545 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Pde3bPhosphodiesterase. (1011 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Calm3Calmodulin 3. (149 aa)
Ace3Angiotensin-converting enzyme. (728 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
Ppp3ccSerine/threonine-protein phosphatase. (478 aa)
Adcyap1r1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (610 aa)
Pde1cPhosphodiesterase. (633 aa)
Gucy1b1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (626 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (247 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
Edn1Endothelin-1-like isoform X1. (202 aa)
Ppp3cbSerine/threonine-protein phosphatase. (492 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (327 aa)
Orai1Calcium release-activated calcium channel protein 1. (300 aa)
Ppp3caSerine/threonine-protein phosphatase. (479 aa)
AceAngiotensin-converting enzyme. (1315 aa)
Agtr1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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