STRINGSTRING
Gnas Gnas Nr4a1 Nr4a1 Adcy5 Adcy5 Adcy1 Adcy1 Atp1a1 Atp1a1 Itpr3 Itpr3 Plcb3 Plcb3 Kcnk9 Kcnk9 Dagla Dagla Daglb Daglb Creb3l2 Creb3l2 Creb3l3 Creb3l3 Atf2 Atf2 Prkcg Prkcg Camk1g Camk1g Atf6b Atf6b Npr1 Npr1 Atf4 Atf4 Cacna1i Cacna1i Cacna1d Cacna1d Adcy6 Adcy6 Prkd2 Prkd2 Camk2g Camk2g Pomc Pomc Adcy8 Adcy8 Atp1a3 Atp1a3 Adcy3 Adcy3 Atf1 Atf1 Lipe Lipe Kcnj5 Kcnj5 LOC105991916 LOC105991916 Atp1a2 Atp1a2 Nr4a2 Nr4a2 Cacna1g Cacna1g Arsi Arsi Prkd3 Prkd3 Calm2 Calm2 Prkca Prkca Cyp11a1 Cyp11a1 Creb5 Creb5 Prkce Prkce Adcy7 Adcy7 Atp1b4 Atp1b4 Kcnk3 Kcnk3 Adcy2 Adcy2 Camk1 Camk1 Agt Agt Camk1d Camk1d Creb3l4 Creb3l4 Adcy4 Adcy4 Creb1 Creb1 Scarb1 Scarb1 Nppa Nppa Atp2b4 Atp2b4 Prkaca Prkaca Plcb4 Plcb4 Cacna1s Cacna1s Atp1b1 Atp1b1 Prkcb Prkcb Camk2b Camk2b Calml3 Calml3 Mc2r Mc2r Adcy9 Adcy9 Calm1 Calm1 Creb3 Creb3 Ptrhd1 Ptrhd1 Camk2a Camk2a Calml4 Calml4 Atp2b1 Atp2b1 Prkacb Prkacb Cacna1c Cacna1c Prkd1 Prkd1 Plcb1 Plcb1 Camk2d Camk2d Gnaq Gnaq Calm3 Calm3 Cacna1h Cacna1h Atp2b2 Atp2b2 Itpr2 Itpr2 ENSDORP00000023022 ENSDORP00000023022 Atp1b2 Atp1b2 Cacna1f Cacna1f Plcb2 Plcb2 Itpr1 Itpr1 Atp1b3 Atp1b3 Gna11 Gna11 Arap1 Arap1 Creb3l1 Creb3l1 Orai1 Orai1 Agtr1 Agtr1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Nr4a1Nuclear receptor subfamily 4 group A member 1. (596 aa)
Adcy5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1186 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (937 aa)
Atp1a1Sodium/potassium-transporting ATPase subunit alpha. (1024 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3 isoform X3. (2668 aa)
Plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
Kcnk9Potassium channel subfamily K member 9; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (369 aa)
DaglaSn1-specific diacylglycerol lipase alpha. (1012 aa)
DaglbSn1-specific diacylglycerol lipase beta. (611 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3. (464 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (507 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Camk1gCalcium/calmodulin-dependent protein kinase type 1G; Belongs to the protein kinase superfamily. (476 aa)
Atf6bCyclic AMP-dependent transcription factor ATF-6 beta. (604 aa)
Npr1Guanylate cyclase. (1060 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (345 aa)
Cacna1iVoltage-dependent T-type calcium channel subunit alpha-1I. (2201 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2039 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Prkd2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (868 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma. (515 aa)
PomcPro-opiomelanocortin isoform X1. (261 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Atp1a3Sodium/potassium-transporting ATPase subunit alpha. (1035 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
Atf1Cyclic AMP-dependent transcription factor ATF-1. (219 aa)
LipeHormone-sensitive lipase isoform X3. (758 aa)
Kcnj5G protein-activated inward rectifier potassium channel 4. (416 aa)
LOC1059919163 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4-like isoform X1; Belongs to the 3-beta-HSD family. (373 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha. (1046 aa)
Nr4a2Nuclear receptor subfamily 4 group A member 2 isoform X1. (598 aa)
Cacna1gVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2385 aa)
ArsiArylsulfatase I. (573 aa)
Prkd3Serine/threonine-protein kinase D3. (806 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (149 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Cyp11a1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (518 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
PrkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (548 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
Atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (359 aa)
Kcnk3Potassium channel subfamily K member 3; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (416 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (854 aa)
Camk1Calcium/calmodulin-dependent protein kinase type 1 isoform X2; Belongs to the protein kinase superfamily. (370 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
Camk1dCalcium/calmodulin-dependent protein kinase type 1D. (375 aa)
Creb3l4Cyclic AMP-responsive element-binding protein 3-like protein 4. (378 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Scarb1Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (472 aa)
NppaNatriuretic peptides A. (153 aa)
Atp2b4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1230 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
Atp1b1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (293 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta. (644 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Mc2rAdrenocorticotropic hormone receptor. (297 aa)
Adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1330 aa)
Calm1Calmodulin 1. (149 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (372 aa)
Ptrhd1Putative peptidyl-tRNA hydrolase PTRHD1. (146 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (488 aa)
Calml4Calmodulin-like protein 4 isoform X1. (153 aa)
Atp2b1Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1019 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Prkd1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (847 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (533 aa)
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (333 aa)
Calm3Calmodulin 3. (149 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H. (2166 aa)
Atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
ENSDORP00000023022annotation not available (388 aa)
Atp1b2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (247 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
Atp1b3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (80 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (313 aa)
Arap1Phosphodiesterase. (965 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (524 aa)
Orai1Calcium release-activated calcium channel protein 1. (300 aa)
Agtr1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.