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Gnaq Gnaq Itpr2 Itpr2 Cacna1f Cacna1f Plcb2 Plcb2 Itpr1 Itpr1 Mrap Mrap Gna11 Gna11 Pde8a Pde8a Creb3l1 Creb3l1 Nr4a1 Nr4a1 Orai1 Orai1 Kcna10 Kcna10 Agtr1 Agtr1 Adcy5 Adcy5 Adcy1 Adcy1 Itpr3 Itpr3 Plcb3 Plcb3 Creb3l2 Creb3l2 Creb3l3 Creb3l3 Atf2 Atf2 Atf6b Atf6b Gnas Gnas Kcna3 Kcna3 Kcna2 Kcna2 Atf4 Atf4 Cacna1i Cacna1i Cacna1d Cacna1d Adcy6 Adcy6 Pomc Pomc Pde8b Pde8b Adcy8 Adcy8 Cyp17a1 Cyp17a1 Adcy3 Adcy3 LOC105991916 LOC105991916 LOC106002066 LOC106002066 Cacna1g Cacna1g Cyp11a1 Cyp11a1 Nr0b1 Nr0b1 Creb5 Creb5 Adcy7 Adcy7 Kcnk3 Kcnk3 Adcy2 Adcy2 Agt Agt Creb3l4 Creb3l4 Pbx1 Pbx1 Adcy4 Adcy4 Creb1 Creb1 Kcna1 Kcna1 Scarb1 Scarb1 Prkaca Prkaca Plcb4 Plcb4 Cacna1s Cacna1s Sp1 Sp1 Mc2r Mc2r Adcy9 Adcy9 Creb3 Creb3 Ptrhd1 Ptrhd1 Kcna4 Kcna4 Nr5a1 Nr5a1 Prkacb Prkacb Cacna1c Cacna1c Kcnk2 Kcnk2 Plcb1 Plcb1 Nceh1 Nceh1 Cacna1h Cacna1h
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (333 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (247 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
MrapMelanocortin-2 receptor accessory protein. (129 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (313 aa)
Pde8aPhosphodiesterase. (698 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (524 aa)
Nr4a1Nuclear receptor subfamily 4 group A member 1. (596 aa)
Orai1Calcium release-activated calcium channel protein 1. (300 aa)
Kcna10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (509 aa)
Agtr1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Adcy5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1186 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (937 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3 isoform X3. (2668 aa)
Plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3. (464 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (507 aa)
Atf6bCyclic AMP-dependent transcription factor ATF-6 beta. (604 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Kcna3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (509 aa)
Kcna2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (345 aa)
Cacna1iVoltage-dependent T-type calcium channel subunit alpha-1I. (2201 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2039 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
PomcPro-opiomelanocortin isoform X1. (261 aa)
Pde8bPhosphodiesterase. (783 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Cyp17a1Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (508 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
LOC1059919163 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4-like isoform X1; Belongs to the 3-beta-HSD family. (373 aa)
LOC106002066Cytochrome P450 11B2, mitochondrial-like; Belongs to the cytochrome P450 family. (420 aa)
Cacna1gVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2385 aa)
Cyp11a1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (518 aa)
Nr0b1Nuclear receptor subfamily 0 group B member 1. (472 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
Kcnk3Potassium channel subfamily K member 3; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (416 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (854 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
Creb3l4Cyclic AMP-responsive element-binding protein 3-like protein 4. (378 aa)
Pbx1pre-B-cell leukemia transcription factor 1 isoform X1. (430 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Kcna1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (496 aa)
Scarb1Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (472 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
Sp1Transcription factor Sp1. (786 aa)
Mc2rAdrenocorticotropic hormone receptor. (297 aa)
Adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1330 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (372 aa)
Ptrhd1Putative peptidyl-tRNA hydrolase PTRHD1. (146 aa)
Kcna4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (653 aa)
Nr5a1Steroidogenic factor 1. (468 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Kcnk2Potassium channel subfamily K member 2 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Nceh1Neutral cholesterol ester hydrolase 1. (408 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H. (2166 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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