STRINGSTRING
Hk3 Hk3 Hk1 Hk1 Gck Gck Parp6 Parp6 Mapk8 Mapk8 Socs2 Socs2 Socs1 Socs1 Cacna1a Cacna1a LOC106000559 LOC106000559 Pklr Pklr Cacna1c Cacna1c Pik3r1 Pik3r1 Cacna1b Cacna1b Mafa Mafa Prkcd Prkcd Mapk1 Mapk1 Pik3r3 Pik3r3 Tnik Tnik Hkdc1 Hkdc1 Adipoq Adipoq Ikbkb Ikbkb Irs4 Irs4 Tnf Tnf Pik3cd Pik3cd Irs1 Irs1 Parp8 Parp8 Slc2a4 Slc2a4 Prkce Prkce Mapk10 Mapk10 Abcc8 Abcc8 Pik3ca Pik3ca Cacna1g Cacna1g Pdx1 Pdx1 Pkm Pkm Hk2 Hk2 Pik3cb Pik3cb Socs3 Socs3 Cacna1d Cacna1d Slc2a2 Slc2a2 Mast3 Mast3 Mapk9 Mapk9 Mtor Mtor Mapk3 Mapk3 Cacna1e Cacna1e Socs4 Socs4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hk3Hexokinase-3. (894 aa)
Hk1Hexokinase-1. (974 aa)
GckPhosphotransferase. (466 aa)
Parp6Poly [ADP-ribose] polymerase. (630 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Socs2Suppressor of cytokine signaling 2. (198 aa)
Socs1Suppressor of cytokine signaling 1. (177 aa)
Cacna1aVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (2254 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
PklrPyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Cacna1bVoltage-dependent N-type calcium channel subunit alpha-1B. (2037 aa)
MafaTranscription factor MafA. (281 aa)
PrkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
TnikTRAF2 and NCK-interacting protein kinase. (1315 aa)
Hkdc1Putative hexokinase HKDC1. (896 aa)
AdipoqAdiponectin. (251 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
Irs4Insulin receptor substrate 4. (1262 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Irs1Insulin receptor substrate 1. (1239 aa)
Parp8Poly [ADP-ribose] polymerase. (483 aa)
Slc2a4Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
PrkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (548 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
Abcc8ATP-binding cassette sub-family C member 8 isoform X1. (1582 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Cacna1gVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2385 aa)
Pdx1Pancreas/duodenum homeobox protein 1. (283 aa)
PkmPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
Hk2Hexokinase-2. (917 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Socs3Suppressor of cytokine signaling 3. (228 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2039 aa)
Slc2a2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (521 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Cacna1eVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2325 aa)
Socs4Suppressor of cytokine signaling 4. (441 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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