STRINGSTRING
Cacna1a Cacna1a Pik3r4-2 Pik3r4-2 Ambra1 Ambra1 Akt2 Akt2 Tbpl1 Tbpl1 Psmc1 Psmc1 Akt3 Akt3 Atxn2 Atxn2 ENSDORP00000027744 ENSDORP00000027744 Kcnc2 Kcnc2 Sem1 Sem1 Psmd13 Psmd13 Atg101 Atg101 Psmc2 Psmc2 Slc25a31 Slc25a31 Atg13 Atg13 Atp2a1 Atp2a1 Vdac1 Vdac1 Psmc3 Psmc3 Oma1 Oma1 Itpr3 Itpr3 Ern1 Ern1 Afg3l1 Afg3l1 ENSDORP00000026425 ENSDORP00000026425 Grin3b Grin3b Atxn1l Atxn1l ENSDORP00000025725 ENSDORP00000025725 Mapk8 Mapk8 Vdac2 Vdac2 Atxn1 Atxn1 ENSDORP00000025238 ENSDORP00000025238 Itpr1 Itpr1 Kcnc3 Kcnc3 Atg14 Atg14 Plcb2 Plcb2 Ppif Ppif Atxn2l Atxn2l Cic Cic Myod1 Myod1 ENSDORP00000023006 ENSDORP00000023006 Rbpjl Rbpjl ENSDORP00000022665 ENSDORP00000022665 Grin1 Grin1 Itpr2 Itpr2 Ryr1 Ryr1 Rb1cc1-2 Rb1cc1-2 Psmb5 Psmb5 Nrbf2 Nrbf2 Grin2d Grin2d Psma3-2 Psma3-2 LOC106000559 LOC106000559 ENSDORP00000021644 ENSDORP00000021644 ENSDORP00000021284 ENSDORP00000021284 Tbp Tbp ENSDORP00000021143 ENSDORP00000021143 Psmb4 Psmb4 Plcb1 Plcb1 Pik3r1 Pik3r1 Pdyn Pdyn ENSDORP00000019550 ENSDORP00000019550 Ulk1 Ulk1 Psmd4 Psmd4 Becn1 Becn1 ENSDORP00000017763 ENSDORP00000017763 Psmb2 Psmb2 Atp2a2 Atp2a2 Adrm1 Adrm1 Psmd7 Psmd7 Gm10053 Gm10053 Sptbn2 Sptbn2 Reln Reln Psmb3 Psmb3 LOC105999307 LOC105999307 ENSDORP00000016358 ENSDORP00000016358 Pik3r3 Pik3r3 Sp1 Sp1 Psma7 Psma7 Osbpl2 Osbpl2 Psmc6 Psmc6 Slc25a5 Slc25a5 ENSDORP00000014998 ENSDORP00000014998 Prkcb Prkcb Trpc3 Trpc3 Psmd3 Psmd3 Psmd1 Psmd1 Plcb4 Plcb4 Bean1 Bean1 Opa1 Opa1 Pik3c3 Pik3c3 Psmb7 Psmb7 Nop56 Nop56 Atxn10 Atxn10 Slc25a4 Slc25a4 Psmd9 Psmd9 Kcnc1 Kcnc1 Vldlr Vldlr Ulk2 Ulk2 Psmb1 Psmb1 Atg2b Atg2b Kat5 Kat5 Pik3cd Pik3cd Wipi2 Wipi2 Grin3a Grin3a Psma2 Psma2 Atg2a Atg2a Kcnd3 Kcnd3 Grin2a Grin2a Pum2 Pum2 Psmd11 Psmd11 Trpc7 Trpc7 Psmd14 Psmd14 ENSDORP00000009926 ENSDORP00000009926 Wipi1 Wipi1 Atp2a3 Atp2a3 Prkca Prkca Mapk10 Mapk10 Psma6 Psma6 Pik3ca Pik3ca Psma1 Psma1 Psma8 Psma8 Dab1 Dab1 Gtf2b Gtf2b Psmd12 Psmd12 Psmd2 Psmd2 Psmd6 Psmd6 Atxn3 Atxn3 Psmc4 Psmc4 Nfya Nfya Rbpj Rbpj Pik3cb Pik3cb Akt1 Akt1 Kcnc4 Kcnc4 Psmb6 Psmb6 Rb1cc1 Rb1cc1 Afg3l2 Afg3l2 Grin2c Grin2c Psmd8 Psmd8 Xbp1 Xbp1 Pik3r4 Pik3r4 Fgf12 Fgf12 Twnk Twnk Gria2 Gria2 Mast3 Mast3 Psmc5 Psmc5 Traf2 Traf2 4921507P07Rik 4921507P07Rik Cyct Cyct Psma5 Psma5 Prkcg Prkcg Mapk9 Mapk9 Slc1a6 Slc1a6 Mtor Mtor Gria3 Gria3 Tbpl2 Tbpl2 Vdac3 Vdac3 Psma3 Psma3 Mcu Mcu Gria1 Gria1 Pum1 Pum1 Rora Rora Plcb3 Plcb3 Psma4 Psma4 Map3k5 Map3k5 Grin2b Grin2b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cacna1aVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (2254 aa)
Pik3r4-2Phosphoinositide 3-kinase regulatory subunit 4. (296 aa)
Ambra1Activating molecule in BECN1-regulated autophagy protein 1. (1243 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Tbpl1TATA box-binding protein-like protein 1 isoform X2. (186 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (439 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Atxn2Ataxin-2. (1047 aa)
ENSDORP00000027744annotation not available (314 aa)
Kcnc2Potassium voltage-gated channel subfamily C member 2 isoform X1; Belongs to the potassium channel family. (422 aa)
Sem1SEM1, 26S proteasome complex subunit. (70 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
Atg101Autophagy-related protein 101. (218 aa)
Psmc226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (460 aa)
Slc25a31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
Atg13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (480 aa)
Atp2a1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1069 aa)
Vdac1Voltage-dependent anion-selective channel protein 1. (296 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (442 aa)
Oma1Metalloendopeptidase OMA1, mitochondrial. (505 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3 isoform X3. (2668 aa)
Ern1Serine/threonine-protein kinase/endoribonuclease IRE1. (406 aa)
Afg3l1AFG3-like protein 1. (782 aa)
ENSDORP00000026425annotation not available (105 aa)
Grin3bGlutamate receptor ionotropic, NMDA 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (933 aa)
Atxn1lAtaxin-1-like. (689 aa)
ENSDORP00000025725annotation not available (105 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Vdac2Voltage-dependent anion-selective channel protein 2. (294 aa)
Atxn1Ataxin-1. (801 aa)
ENSDORP00000025238annotation not available (136 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2702 aa)
Kcnc3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (709 aa)
Atg14Beclin 1-associated autophagy-related key regulator. (492 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
PpifPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa)
Atxn2lAtaxin-2-like protein isoform X11. (144 aa)
CicProtein capicua homolog isoform X1. (2470 aa)
Myod1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (325 aa)
ENSDORP00000023006annotation not available (100 aa)
RbpjlRecombining binding protein suppressor of hairless-like protein. (542 aa)
ENSDORP00000022665annotation not available (680 aa)
Grin1LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 1. (926 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2678 aa)
Ryr1Ryanodine receptor 1. (4894 aa)
Rb1cc1-2RB1-inducible coiled-coil protein 1 isoform X2. (229 aa)
Psmb5Proteasome subunit beta. (160 aa)
Nrbf2Nuclear receptor-binding factor 2 isoform X1. (288 aa)
Grin2dGlutamate receptor, ionotropic, NMDA2D (epsilon 4). (1128 aa)
Psma3-2Proteasome subunit alpha type. (241 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
ENSDORP00000021644annotation not available (241 aa)
ENSDORP00000021284annotation not available (297 aa)
TbpTATA-box-binding protein. (318 aa)
ENSDORP00000021143annotation not available (105 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (239 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Pdynproenkephalin-B. (237 aa)
ENSDORP00000019550annotation not available (99 aa)
Ulk1Serine/threonine-protein kinase ULK1. (1012 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
Becn1Beclin-1. (448 aa)
ENSDORP00000017763annotation not available (211 aa)
Psmb2Proteasome subunit beta. (176 aa)
Atp2a2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (986 aa)
Adrm1Proteasomal ubiquitin receptor ADRM1. (407 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (324 aa)
Gm10053Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
Sptbn2Spectrin beta chain; Belongs to the spectrin family. (2383 aa)
RelnReelin. (3415 aa)
Psmb3Proteasome subunit beta. (205 aa)
LOC105999307Potassium voltage-gated channel subfamily C member 1-like; Belongs to the potassium channel family. (445 aa)
ENSDORP00000016358annotation not available (337 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Sp1Transcription factor Sp1. (786 aa)
Psma7Proteasome endopeptidase complex. (178 aa)
Osbpl2Oxysterol-binding protein; Belongs to the OSBP family. (475 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
Slc25a5ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ENSDORP00000014998annotation not available (169 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
Trpc3Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (836 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (532 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (938 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
Bean1Protein BEAN1. (256 aa)
Opa1LOW QUALITY PROTEIN: dynamin-like 120 kDa protein, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (922 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
Psmb7Proteasome subunit beta. (277 aa)
Nop56Nucleolar protein 56. (261 aa)
Atxn10Ataxin 10. (433 aa)
Slc25a4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (213 aa)
Kcnc1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
VldlrVery low-density lipoprotein receptor. (845 aa)
Ulk2Serine/threonine-protein kinase ULK2 isoform X1. (1036 aa)
Psmb1Proteasome subunit beta. (241 aa)
Atg2bAutophagy-related protein 2 homolog B. (2077 aa)
Kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Wipi2WD repeat domain phosphoinositide-interacting protein 2 isoform X2. (445 aa)
Grin3aGlutamate receptor ionotropic, NMDA 3A isoform X1. (1134 aa)
Psma2Proteasome subunit alpha type. (234 aa)
Atg2aAutophagy-related protein 2 homolog A isoform X3. (1918 aa)
Kcnd3Potassium voltage-gated channel subfamily D member 3 isoform X1; Belongs to the potassium channel family. (655 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1301 aa)
Pum2Pumilio homolog 2. (1029 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
Trpc7Short transient receptor potential channel 7 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
ENSDORP00000009926annotation not available (80 aa)
Wipi1WD repeat domain phosphoinositide-interacting protein 1 isoform X2. (453 aa)
Atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1009 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
Psma6Proteasome subunit alpha type. (246 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Psma1Proteasome subunit alpha type. (255 aa)
Psma8Proteasome subunit alpha type. (256 aa)
Dab1Disabled homolog 1 isoform X1. (555 aa)
Gtf2bTranscription initiation factor IIB isoform X2. (316 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
Atxn3Ataxin-3 isoform X1. (355 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (406 aa)
NfyaNuclear transcription factor Y subunit alpha isoform X3. (347 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Kcnc4Potassium voltage-gated channel subfamily C member 4 isoform X2; Belongs to the potassium channel family. (630 aa)
Psmb6Proteasome subunit beta. (239 aa)
Rb1cc1RB1 inducible coiled-coil 1. (164 aa)
Afg3l2AFG3-like protein 2. (796 aa)
Grin2cGlutamate receptor ionotropic, NMDA 2C. (1021 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (287 aa)
Xbp1LOW QUALITY PROTEIN: X-box-binding protein 1. (275 aa)
Pik3r4Phosphoinositide-3-kinase regulatory subunit 4. (208 aa)
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (241 aa)
TwnkTwinkle protein, mitochondrial. (680 aa)
Gria2Glutamate receptor 2. (842 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
Traf2TNF receptor-associated factor. (484 aa)
4921507P07RikUncharacterized protein C7orf31 homolog. (560 aa)
CyctCytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Psma5Proteasome subunit alpha type. (242 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
Slc1a6Amino acid transporter. (544 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Gria3Glutamate receptor 3 isoform X2. (894 aa)
Tbpl2TATA box-binding protein-like protein 2. (354 aa)
Vdac3Voltage-dependent anion-selective channel protein 3. (283 aa)
Psma3Proteasome 20S subunit alpha 3. (232 aa)
McuCalcium uniporter protein, mitochondrial. (283 aa)
Gria1Glutamate receptor 1 isoform X2. (906 aa)
Pum1Pumilio homolog 1 isoform X6. (984 aa)
RoraNuclear receptor ROR-alpha. (523 aa)
Plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5. (144 aa)
Grin2bGlutamate receptor ionotropic, NMDA 2B. (1103 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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