STRINGSTRING
Pycard Pycard ENSDORP00000022835 ENSDORP00000022835 Nod1 Nod1 C1r C1r ENSDORP00000023508 ENSDORP00000023508 Mapk14 Mapk14 ENSDORP00000024578 ENSDORP00000024578 C1qc C1qc Mapk8 Mapk8 Fos Fos C1s C1s Tmed7 Tmed7 Casp3 Casp3 Itgam Itgam Calm3 Calm3 C1rl C1rl Calml4 Calml4 Irak1 Irak1 Rhoa Rhoa Il1a Il1a LOC105985511 LOC105985511 Calm1 Calm1 Gnai1 Gnai1 Mapk1 Mapk1 C1qa C1qa Traf6 Traf6 Calml3 Calml3 Hc Hc Irf8 Irf8 Irak4 Irak4 Irf3 Irf3 Gnai3 Gnai3 Ly96 Ly96 Mapk13 Mapk13 Casp7 Casp7 Efcab3 Efcab3 C1qb C1qb Tmed3 Tmed3 Il23a Il23a Rela Rela Tnf Tnf ENSDORP00000011621 ENSDORP00000011621 C4b C4b Il10 Il10 Ccdc125 Ccdc125 Nlrp3 Nlrp3 Mapk10 Mapk10 Calm2 Calm2 Cfl1 Cfl1 C3 C3 Il1b Il1b Serping1 Serping1 Itga5 Itga5 Il12b Il12b Itgb1 Itgb1 Nfkb1 Nfkb1 Gnai2 Gnai2 Cfl2 Cfl2 Myd88 Myd88 Mapk9 Mapk9 Irf1 Irf1 Rhoc Rhoc Mapk3 Mapk3 Mapk12 Mapk12 Tlr4 Tlr4 Nos2 Nos2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PycardApoptosis-associated speck-like protein containing a CARD. (190 aa)
ENSDORP00000022835annotation not available (193 aa)
Nod1Nucleotide-binding oligomerization domain-containing protein 1. (903 aa)
C1rComplement C1r subcomponent; Belongs to the peptidase S1 family. (141 aa)
ENSDORP00000023508annotation not available (156 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
ENSDORP00000024578annotation not available (134 aa)
C1qcComplement C1q subcomponent subunit C. (245 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
FosProto-oncogene c-Fos. (380 aa)
C1sComplement C1s subcomponent; Belongs to the peptidase S1 family. (549 aa)
Tmed7Transmembrane emp24 domain-containing protein 7-like. (203 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
ItgamIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1143 aa)
Calm3Calmodulin 3. (149 aa)
C1rlComplement C1r subcomponent-like protein isoform X2; Belongs to the peptidase S1 family. (426 aa)
Calml4Calmodulin-like protein 4 isoform X1. (153 aa)
Irak1Interleukin-1 receptor-associated kinase 1. (714 aa)
RhoaTransforming protein RhoA. (193 aa)
Il1aInterleukin-1; Belongs to the IL-1 family. (270 aa)
LOC105985511TIR domain-containing adapter molecule 2-like. (233 aa)
Calm1Calmodulin 1. (149 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
C1qaComplement C1q subcomponent subunit A. (246 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (529 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
HcLOW QUALITY PROTEIN: complement C5-like. (1501 aa)
Irf8Interferon regulatory factor 8 isoform X1. (292 aa)
Irak4Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa)
Irf3Interferon regulatory factor 3. (424 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Ly96Lymphocyte antigen 96 isoform X1. (160 aa)
Mapk13Mitogen-activated protein kinase. (334 aa)
Casp7Caspase-7; Belongs to the peptidase C14A family. (305 aa)
Efcab3EF-hand calcium-binding domain-containing protein 3. (433 aa)
C1qbComplement C1q subcomponent subunit B. (254 aa)
Tmed3Transmembrane emp24 domain-containing protein 3. (179 aa)
Il23aInterleukin-23 subunit alpha. (191 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
ENSDORP00000011621annotation not available (186 aa)
C4bComplement C4-A. (1634 aa)
Il10Interleukin-10. (178 aa)
Ccdc125Coiled-coil domain-containing protein 125. (484 aa)
Nlrp3NACHT, LRR and PYD domains-containing protein 3. (1027 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (149 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (168 aa)
C3Complement C3. (1661 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Serping1Plasma protease C1 inhibitor; Belongs to the serpin family. (499 aa)
Itga5Integrin alpha-5; Belongs to the integrin alpha chain family. (1057 aa)
Il12bInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Cfl2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (338 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
Irf1Interferon regulatory factor. (132 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Mapk12Mitogen-activated protein kinase. (351 aa)
Tlr4Toll-like receptor 4 isoform X2; Belongs to the Toll-like receptor family. (842 aa)
Nos2Nitric oxide synthase; Produces nitric oxide (NO). (1149 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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