STRINGSTRING
LOC106000017 LOC106000017 Crebbp Crebbp Ywhag Ywhag Nras Nras LOC105997010 LOC105997010 Traf5 Traf5 ENSDORP00000022774 ENSDORP00000022774 Rbl2 Rbl2 ENSDORP00000022835 ENSDORP00000022835 LOC105989352 LOC105989352 Rbpjl Rbpjl LOC105996995 LOC105996995 ENSDORP00000023286 ENSDORP00000023286 Ccnd3 Ccnd3 H2bc3 H2bc3 Trp53 Trp53 Hdac9 Hdac9 H2bc18 H2bc18 Chek1 Chek1 Ywhab Ywhab ENSDORP00000027189 ENSDORP00000027189 Psmc1 Psmc1 Ccr5 Ccr5 Tbpl1 Tbpl1 Scin Scin LOC105996994 LOC105996994 LOC106002438 LOC106002438 LOC105997002 LOC105997002 Creb3l1 Creb3l1 ENSDORP00000025871 ENSDORP00000025871 Vac14 Vac14 Parp6 Parp6 Hras Hras LOC106000013 LOC106000013 Actn1 Actn1 Hnrnpk Hnrnpk Atp6v0d2 Atp6v0d2 Traf1 Traf1 LOC105996819 LOC105996819 ENSDORP00000015336 ENSDORP00000015336 Hdac5 Hdac5 Cdk6 Cdk6 H2bc1 H2bc1 LOC105996996 LOC105996996 ENSDORP00000024466 ENSDORP00000024466 Stat3 Stat3 Ubr4 Ubr4 LOC105996929 LOC105996929 Bak1 Bak1 LOC106001397 LOC106001397 LOC106000030 LOC106000030 Snd1 Snd1 Ccnd1 Ccnd1 Pik3r3 Pik3r3 Cdk2 Cdk2 LOC105985231 LOC105985231 Rac1 Rac1 LOC106000028 LOC106000028 Rbl1 Rbl1 Mapk1 Mapk1 Mapkapk2 Mapkapk2 Ywhah Ywhah Lpxn Lpxn Gtf2h2 Gtf2h2 Creb3 Creb3 LOC105992280-2 LOC105992280-2 Scrib Scrib Rhoa Rhoa Pxn Pxn LOC105996339 LOC105996339 LOC105992280 LOC105992280 ENSDORP00000018543 ENSDORP00000018543 Gtf2h3 Gtf2h3 Ddx3x Ddx3x LOC106000027 LOC106000027 Rb1 Rb1 LOC105997008 LOC105997008 Ywhaq Ywhaq LOC105997053 LOC105997053 Hdac7 Hdac7 LOC105980807 LOC105980807 Hdac10 Hdac10 Cdc20 Cdc20 Dnaja3 Dnaja3 Irf3 Irf3 Prkaca Prkaca Ccne2 Ccne2 Tradd Tradd Gsn Gsn LOC105996972 LOC105996972 Bax Bax Prkacb Prkacb Ywhae Ywhae Casp3 Casp3 Pik3r1 Pik3r1 LOC105999998 LOC105999998 Chd4 Chd4 LOC105984866 LOC105984866 Kras Kras Ccnd2 Ccnd2 Tbp Tbp Cdkn2b Cdkn2b Ccr4 Ccr4 LOC106000559 LOC106000559 Hpn Hpn Hdac4 Hdac4 Gtf2a1l Gtf2a1l Egr2 Egr2 Ikbkg Ikbkg Grb2 Grb2 Ddb1 Ddb1 Hdac1 Hdac1 Stat5a Stat5a Syk Syk Lyn Lyn Srf Srf Egr3 Egr3 Cdkn1b Cdkn1b Ccna1 Ccna1 Il6st Il6st Bad Bad Rasa2 Rasa2 ENSDORP00000002235 ENSDORP00000002235 Polb Polb Vdac3 Vdac3 Creb3l2 Creb3l2 ENSDORP00000002870 ENSDORP00000002870 Mrps18b Mrps18b LOC105996964 LOC105996964 Tbpl2 Tbpl2 Creb3l3 Creb3l3 Mapk3 Mapk3 Rhoc Rhoc Atf2 Atf2 Ube3a Ube3a Gtf2h1 Gtf2h1 Traf2 Traf2 Atf6b Atf6b Mast3 Mast3 Atf4 Atf4 Pik3cb Pik3cb Rbpj Rbpj Mad1l1 Mad1l1 Kat2a Kat2a LOC105996958 LOC105996958 Mdm2 Mdm2 Cdk4 Cdk4 Gtf2e1 Gtf2e1 Nfkb1 Nfkb1 Ccna2 Ccna2 Gtf2a2 Gtf2a2 Ccne1 Ccne1 Cdc20b Cdc20b Gtf2b Gtf2b Pkm Pkm Eif2ak2 Eif2ak2 Pik3ca Pik3ca Hdac11 Hdac11 Ccr3 Ccr3 Lrrc1 Lrrc1 Ep300 Ep300 Creb5 Creb5 Gramd1a Gramd1a Ywhaz Ywhaz Gtf2a1 Gtf2a1 Ranbp1 Ranbp1 Rel Rel Kras-2 Kras-2 Csde1 Csde1 Creb3l4 Creb3l4 LOC105988993 LOC105988993 Ptk7 Ptk7 Usp7 Usp7 Parp8 Parp8 ENSDORP00000011621 ENSDORP00000011621 Snw1 Snw1 Pik3cd Pik3cd Creb1 Creb1 Rela Rela Hdac3 Hdac3 Abcf2 Abcf2 Jak3 Jak3 Nfkbia Nfkbia Skp2 Skp2 Hdac2 Hdac2 Nfkb2 Nfkb2 Jak1 Jak1 Hdac8 Hdac8 Traf3 Traf3 Atp6v0d1 Atp6v0d1 Irf7 Irf7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106000017Histone H3.1-like. (103 aa)
CrebbpCREB-binding protein. (2432 aa)
Ywhag14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
NrasGTPase NRas. (189 aa)
LOC105997010Histone H2B; Belongs to the histone H2B family. (126 aa)
Traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
ENSDORP00000022774annotation not available (389 aa)
Rbl2Retinoblastoma-like protein 2. (1051 aa)
ENSDORP00000022835annotation not available (193 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
RbpjlRecombining binding protein suppressor of hairless-like protein. (542 aa)
LOC105996995Histone H2B type 1. (126 aa)
ENSDORP00000023286annotation not available (584 aa)
Ccnd3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa)
H2bc3Histone H2B; Belongs to the histone H2B family. (126 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
Hdac9Histone deacetylase 9 isoform X4. (114 aa)
H2bc18Histone H2B; Belongs to the histone H2B family. (126 aa)
Chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
Ywhab14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
ENSDORP00000027189annotation not available (164 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (439 aa)
Ccr5C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (357 aa)
Tbpl1TATA box-binding protein-like protein 1 isoform X2. (186 aa)
ScinAdseverin. (696 aa)
LOC105996994Histone H2B type 1. (126 aa)
LOC106002438Interleukin-6 receptor subunit beta-like. (123 aa)
LOC105997002Histone H3.1-like. (103 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (524 aa)
ENSDORP00000025871annotation not available (284 aa)
Vac14Protein VAC14 homolog. (783 aa)
Parp6Poly [ADP-ribose] polymerase. (630 aa)
HrasGTPase HRas isoform X1. (192 aa)
LOC106000013Histone H4-like. (103 aa)
Actn1Alpha-actinin-1. (848 aa)
HnrnpkHeterogeneous nuclear ribonucleoprotein K isoform X2. (466 aa)
Atp6v0d2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
Traf1TNF receptor-associated factor. (408 aa)
LOC10599681914-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
ENSDORP00000015336annotation not available (189 aa)
Hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1119 aa)
Cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
H2bc1Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC105996996Histone H2B type 1. (126 aa)
ENSDORP00000024466annotation not available (547 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Ubr4E3 ubiquitin-protein ligase UBR4. (5010 aa)
LOC105996929Uncharacterized LOC105996929. (103 aa)
Bak1Bcl-2 homologous antagonist/killer. (211 aa)
LOC106001397Patr class I histocompatibility antigen, B-1 alpha chain-like; Belongs to the MHC class I family. (273 aa)
LOC106000030Histone H2B; Belongs to the histone H2B family. (126 aa)
Snd1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
Ccnd1G1/S-specific cyclin-D1. (156 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Cdk2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
LOC105985231Histone H2B; Belongs to the histone H2B family. (126 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
LOC106000028Histone H2B type 1. (126 aa)
Rbl1Retinoblastoma-like protein 1. (1063 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Mapkapk2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (353 aa)
Ywhah14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
LpxnLeupaxin; Belongs to the paxillin family. (386 aa)
Gtf2h2General transcription factor II H, polypeptide 2. (356 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (372 aa)
LOC105992280-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ScribProtein scribble homolog. (1608 aa)
RhoaTransforming protein RhoA. (193 aa)
PxnPaxillin isoform X3; Belongs to the paxillin family. (547 aa)
LOC105996339Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
LOC105992280Histone H4. (103 aa)
ENSDORP00000018543annotation not available (129 aa)
Gtf2h3General transcription factor IIH subunit 3 isoform X1. (309 aa)
Ddx3xATP-dependent RNA helicase DDX3X; Belongs to the DEAD box helicase family. (662 aa)
LOC106000027Histone H2B type 1. (126 aa)
Rb1Retinoblastoma-associated protein isoform X1. (926 aa)
LOC105997008Histone H2B; Belongs to the histone H2B family. (126 aa)
Ywhaq14-3-3 protein theta; Belongs to the 14-3-3 family. (125 aa)
LOC105997053Histone H4. (103 aa)
Hdac7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (950 aa)
LOC105980807Nuclear body protein SP140-like. (488 aa)
Hdac10Histone deacetylase 10 isoform X5. (295 aa)
Cdc20Cell division cycle protein 20 homolog. (498 aa)
Dnaja3dnaJ homolog subfamily A member 3, mitochondrial isoform X1. (480 aa)
Irf3Interferon regulatory factor 3. (424 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Ccne2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein. (309 aa)
GsnGelsolin isoform X2. (568 aa)
LOC105996972HLA class I histocompatibility antigen, B-46 alpha chain-like; Belongs to the MHC class I family. (220 aa)
BaxApoptosis regulator BAX. (143 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Ywhae14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC105999998Uncharacterized LOC105999998. (103 aa)
Chd4chromodomain-helicase-DNA-binding protein 4 isoform X2. (1942 aa)
LOC105984866Histone H2B; Belongs to the histone H2B family. (126 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
Ccnd2G1/S-specific cyclin-D2; Belongs to the cyclin family. (224 aa)
TbpTATA-box-binding protein. (318 aa)
Cdkn2bCyclin-dependent kinase 4 inhibitor B-like. (139 aa)
Ccr4C-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
HpnSerine protease hepsin isoform X2; Belongs to the peptidase S1 family. (416 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1062 aa)
Gtf2a1lTFIIA-alpha and beta-like factor isoform X1. (467 aa)
Egr2E3 SUMO-protein ligase EGR2. (72 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Ddb1DNA damage-binding protein 1. (1025 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (477 aa)
Stat5aSignal transducer and activator of transcription. (793 aa)
SykTyrosine-protein kinase. (633 aa)
LynTyrosine-protein kinase. (512 aa)
SrfSerum response factor. (508 aa)
Egr3Early growth response protein 3 isoform X1. (387 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (106 aa)
Ccna1cyclin-A1; Belongs to the cyclin family. (420 aa)
Il6stInterleukin-6 receptor subunit beta. (828 aa)
BadBcl2-associated agonist of cell death isoform X1. (154 aa)
Rasa2Ras GTPase-activating protein 2. (823 aa)
ENSDORP00000002235annotation not available (390 aa)
PolbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (195 aa)
Vdac3Voltage-dependent anion-selective channel protein 3. (283 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
ENSDORP00000002870annotation not available (124 aa)
Mrps18b28S ribosomal protein S18b, mitochondrial. (212 aa)
LOC105996964HLA class I histocompatibility antigen, A-11 alpha chain-like; Belongs to the MHC class I family. (345 aa)
Tbpl2TATA box-binding protein-like protein 2. (354 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3. (464 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (507 aa)
Ube3aUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (873 aa)
Gtf2h1General transcription factor IIH subunit 1 isoform X2. (552 aa)
Traf2TNF receptor-associated factor. (484 aa)
Atf6bCyclic AMP-dependent transcription factor ATF-6 beta. (604 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (345 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
Mad1l1Mitotic spindle assembly checkpoint protein MAD1 isoform X1. (717 aa)
Kat2aHistone acetyltransferase KAT2A isoform X1. (829 aa)
LOC105996958LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-27 alpha chain-like; Belongs to the MHC class I family. (322 aa)
Mdm2E3 ubiquitin-protein ligase Mdm2. (446 aa)
Cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Gtf2e1General transcription factor IIE subunit 1. (439 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Ccna2cyclin-A2; Belongs to the cyclin family. (425 aa)
Gtf2a2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
Ccne1G1/S-specific cyclin-E1; Belongs to the cyclin family. (413 aa)
Cdc20bCell division cycle protein 20 homolog B. (522 aa)
Gtf2bTranscription initiation factor IIB isoform X2. (316 aa)
PkmPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
Eif2ak2Interferon-induced, double-stranded RNA-activated protein kinase isoform X2. (476 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Hdac11Histone deacetylase 11. (346 aa)
Ccr3C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (357 aa)
Lrrc1Leucine-rich repeat-containing protein 1. (419 aa)
Ep300Histone acetyltransferase p300. (2345 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
Gramd1aGRAM domain-containing protein 1A. (161 aa)
Ywhaz14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
Gtf2a1Transcription initiation factor IIA subunit 1. (359 aa)
Ranbp1Ran-specific GTPase-activating protein isoform X2. (203 aa)
RelProto-oncogene c-Rel. (590 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Creb3l4Cyclic AMP-responsive element-binding protein 3-like protein 4. (378 aa)
LOC105988993Cyclin-dependent kinase inhibitor 2A-like. (90 aa)
Ptk7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
Usp7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (891 aa)
Parp8Poly [ADP-ribose] polymerase. (483 aa)
ENSDORP00000011621annotation not available (186 aa)
Snw1SNW domain-containing protein 1. (539 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
Hdac3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa)
Abcf2ATP-binding cassette sub-family F member 2. (624 aa)
Jak3Tyrosine-protein kinase JAK3. (999 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
Skp2S-phase kinase-associated protein 2 isoform X1. (424 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
Nfkb2Nuclear factor NF-kappa-B p100 subunit. (895 aa)
Jak1Tyrosine-protein kinase. (1155 aa)
Hdac8Histone deacetylase 8. (377 aa)
Traf3TNF receptor-associated factor. (549 aa)
Atp6v0d1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
Irf7Interferon regulatory factor 7 isoform X2. (432 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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