STRINGSTRING
Epas1 Epas1 ENSDORP00000024671 ENSDORP00000024671 LOC105987731 LOC105987731 Pak2 Pak2 ENSDORP00000023736 ENSDORP00000023736 Hras Hras ENSDORP00000026363 ENSDORP00000026363 Akt2 Akt2 Akt3 Akt3 Grb2 Grb2 Pak7 Pak7 Pak4-2 Pak4-2 LOC105989352 LOC105989352 LOC105987800 LOC105987800 Nras Nras Arnt2 Arnt2 Crebbp Crebbp Crk Crk LOC106000559 LOC106000559 Pdgfb Pdgfb Tgfa Tgfa Arnt Arnt Kras Kras Crkl Crkl Sos2 Sos2 Vhl Vhl Pik3r1 Pik3r1 Met Met Araf Araf Hgf Hgf Tfe3 Tfe3 Rap1b Rap1b Ets1 Ets1 LOC105998252 LOC105998252 Braf Braf Mapk1 Mapk1 Pak1 Pak1 Elob Elob Pik3r3 Pik3r3 Gab1 Gab1 Raf1 Raf1 Rbx1 Rbx1 Rac1 Rac1 Egln3 Egln3 Tgfb3 Tgfb3 Pik3cd Pik3cd Slc2a1 Slc2a1 Rap1a Rap1a Csde1 Csde1 Kras-2 Kras-2 Flcn Flcn Ep300 Ep300 Pik3ca Pik3ca Ptpn11 Ptpn11 Pak4 Pak4 Egln1 Egln1 Pik3cb Pik3cb Akt1 Akt1 Prcc Prcc Hif1a Hif1a Mast3 Mast3 Tgfb2 Tgfb2 ENSDORP00000003419 ENSDORP00000003419 Tgfb1 Tgfb1 Rapgef1 Rapgef1 Fh1 Fh1 Mapk3 Mapk3 Sos1 Sos1 Pak3 Pak3 Bad Bad Map2k1 Map2k1 Map2k2 Map2k2 Cul2 Cul2 Eloc Eloc ENSDORP00000027934 ENSDORP00000027934 Pak6 Pak6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Epas1Endothelial PAS domain-containing protein 1 isoform X2. (877 aa)
ENSDORP00000024671annotation not available (72 aa)
LOC105987731Uncharacterized protein LOC105987731. (169 aa)
Pak2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (507 aa)
ENSDORP00000023736annotation not available (111 aa)
HrasGTPase HRas isoform X1. (192 aa)
ENSDORP00000026363annotation not available (164 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Pak7Non-specific serine/threonine protein kinase. (338 aa)
Pak4-2Non-specific serine/threonine protein kinase. (110 aa)
LOC105989352Cell division control protein 42 homolog. (243 aa)
LOC105987800Vascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (185 aa)
NrasGTPase NRas. (189 aa)
Arnt2Aryl hydrocarbon receptor nuclear translocator 2. (91 aa)
CrebbpCREB-binding protein. (2432 aa)
CrkAdapter molecule crk. (304 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
TgfaProtransforming growth factor alpha. (156 aa)
ArntAryl hydrocarbon receptor nuclear translocator. (320 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
CrklCrk-like protein. (303 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
VhlVon Hippel-Lindau disease tumor suppressor. (204 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
MetHepatocyte growth factor receptor. (1382 aa)
ArafSerine/threonine-protein kinase A-Raf. (606 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
Tfe3Transcription factor E3 isoform X1. (575 aa)
Rap1bRas-related protein Rap-1b. (184 aa)
Ets1Protein C-ets-1. (441 aa)
LOC105998252Transcription elongation factor B polypeptide 2 pseudogene. (103 aa)
BrafSerine/threonine-protein kinase B-raf. (705 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Pak1Non-specific serine/threonine protein kinase. (544 aa)
ElobTranscription elongation factor B polypeptide 2. (72 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Gab1GRB2-associated-binding protein 1. (707 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (590 aa)
Rbx1E3 ubiquitin-protein ligase RBX1. (117 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Egln3LOW QUALITY PROTEIN: egl nine homolog 3. (209 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Slc2a1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
Rap1aRas-related protein Rap-1A. (178 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
FlcnFolliculin. (579 aa)
Ep300Histone acetyltransferase p300. (2345 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (583 aa)
Pak4Non-specific serine/threonine protein kinase. (587 aa)
Egln1Egl nine homolog 1. (128 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
PrccProline-rich protein PRCC. (491 aa)
Hif1aHypoxia-inducible factor 1-alpha. (246 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
ENSDORP00000003419annotation not available (100 aa)
Tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
Rapgef1Rap guanine nucleotide exchange factor 1 isoform X1. (1198 aa)
Fh1Fumarate hydratase, mitochondrial. (466 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Pak3Non-specific serine/threonine protein kinase. (559 aa)
BadBcl2-associated agonist of cell death isoform X1. (154 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Cul2Cullin-2; Belongs to the cullin family. (645 aa)
ElocTranscription elongation factor B polypeptide 1; Belongs to the SKP1 family. (112 aa)
ENSDORP00000027934annotation not available (118 aa)
Pak6Non-specific serine/threonine protein kinase. (668 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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