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Tcf7l1 Tcf7l1 Stat5a Stat5a Ccna1 Ccna1 Map2k2 Map2k2 Map2k1 Map2k1 Bad Bad Csf2 Csf2 Sos1 Sos1 ENSDORP00000002235 ENSDORP00000002235 Mapk3 Mapk3 Mtor Mtor Mast3 Mast3 Tcf7 Tcf7 Akt1 Akt1 Pik3cb Pik3cb Kit Kit Nfkb1 Nfkb1 Ccna2 Ccna2 Lef1 Lef1 Ppard Ppard Pml Pml Pik3ca Pik3ca Csf1r Csf1r Flt3 Flt3 Tcf7l2 Tcf7l2 Kras-2 Kras-2 LOC106001479 LOC106001479 Csde1 Csde1 Zbtb16 Zbtb16 Chuk Chuk Pik3cd Pik3cd Rela Rela Ikbkb Ikbkb Mpo Mpo Runx1t1 Runx1t1 Spib Spib Raf1 Raf1 Fcgr1 Fcgr1 Pim2 Pim2 Ccnd1 Ccnd1 Pim1 Pim1 Pik3r3 Pik3r3 Spi1 Spi1 Eif4ebp1 Eif4ebp1 Mapk1 Mapk1 Braf Braf Jup Jup Araf Araf Pik3r1 Pik3r1 Itgam Itgam Sos2 Sos2 Rps6kb2 Rps6kb2 Kras Kras Rara Rara LOC106000559 LOC106000559 Cebpa Cebpa Nras Nras Per2 Per2 ENSDORP00000023223 ENSDORP00000023223 Stat3 Stat3 Dusp6 Dusp6 Hras Hras Myc Myc Bcl2a1 Bcl2a1 Cebpe Cebpe Akt2 Akt2 LOC106002396 LOC106002396 Akt3 Akt3 Grb2 Grb2 Ikbkg Ikbkg
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tcf7l1Transcription factor 7-like 1. (524 aa)
Stat5aSignal transducer and activator of transcription. (793 aa)
Ccna1cyclin-A1; Belongs to the cyclin family. (420 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
BadBcl2-associated agonist of cell death isoform X1. (154 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (140 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
ENSDORP00000002235annotation not available (390 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Tcf7Transcription factor 7 isoform X10. (344 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
KitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Ccna2cyclin-A2; Belongs to the cyclin family. (425 aa)
Lef1Lymphoid enhancer-binding factor 1. (370 aa)
PpardPeroxisome proliferator-activated receptor delta isoform X1. (433 aa)
PmlProtein PML isoform X1. (830 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Csf1rMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
Flt3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
Tcf7l2Transcription factor 7-like 2. (299 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
LOC106001479Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (492 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Zbtb16Zinc finger and BTB domain-containing protein 16 isoform X1. (673 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
MpoMyeloperoxidase. (715 aa)
Runx1t1Protein CBFA2T1 isoform X1. (580 aa)
SpibTranscription factor Spi-B. (262 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (590 aa)
Fcgr1High affinity immunoglobulin gamma Fc receptor I-like isoform X2. (387 aa)
Pim2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (371 aa)
Ccnd1G1/S-specific cyclin-D1. (156 aa)
Pim1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (250 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Spi1Transcription factor PU.1. (293 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
BrafSerine/threonine-protein kinase B-raf. (705 aa)
JupJunction plakoglobin isoform X1. (745 aa)
ArafSerine/threonine-protein kinase A-Raf. (606 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
ItgamIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1143 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
Rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
RaraRetinoic acid receptor alpha. (343 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
CebpaCCAAT/enhancer-binding protein alpha. (369 aa)
NrasGTPase NRas. (189 aa)
Per2Period circadian protein homolog 2. (1260 aa)
ENSDORP00000023223annotation not available (74 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
HrasGTPase HRas isoform X1. (192 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
Bcl2a1Bcl-2-related protein A1. (139 aa)
CebpeCCAAT/enhancer-binding protein. (281 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC106002396Transcription factor 7-like 2. (125 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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