STRINGSTRING
Traf3 Traf3 Itga3 Itga3 Skp2 Skp2 Nfkbia Nfkbia Ikbkb Ikbkb Col4a6 Col4a6 Rela Rela Pik3cd Pik3cd Col4a4 Col4a4 Gadd45g Gadd45g Lama4 Lama4 Col4a2 Col4a2 Birc2 Birc2 Xiap Xiap Lama1 Lama1 Gadd45a Gadd45a Chuk Chuk ENSDORP00000026425 ENSDORP00000026425 ENSDORP00000026359 ENSDORP00000026359 ENSDORP00000025725 ENSDORP00000025725 Myc Myc Fn1 Fn1 Cks2 Cks2 Secisbp2 Secisbp2 Cdk6 Cdk6 ENSDORP00000024829 ENSDORP00000024829 Bak1 Bak1 Trp53 Trp53 E2f3 E2f3 ENSDORP00000023006 ENSDORP00000023006 Bcl2 Bcl2 Traf5 Traf5 Col4a1 Col4a1 LOC106000559 LOC106000559 Cdkn2b Cdkn2b ENSDORP00000021562 ENSDORP00000021562 ENSDORP00000021143 ENSDORP00000021143 Rarb Rarb Lama2 Lama2 Pik3r1 Pik3r1 Casp3 Casp3 Ptk2 Ptk2 ENSDORP00000019550 ENSDORP00000019550 Rb1 Rb1 Gadd45b Gadd45b Max Max Itgav Itgav Gm10053 Gm10053 Cdk2 Cdk2 Pik3r3 Pik3r3 ENSDORP00000016209 ENSDORP00000016209 Ccnd1 Ccnd1 Lamc1 Lamc1 Ptgs2 Ptgs2 E2f2 E2f2 Cyct Cyct 4921507P07Rik 4921507P07Rik Traf2 Traf2 Mast3 Mast3 Itga6 Itga6 Itga2b Itga2b Akt1 Akt1 Pik3cb Pik3cb Cdk4 Cdk4 Lama3 Lama3 Lamb2 Lamb2 Nfkb1 Nfkb1 Fhit Fhit Ddb2 Ddb2 Polk Polk Itgb1 Itgb1 Ccne1 Ccne1 Zbtb17 Zbtb17 Pten Pten Apaf1 Apaf1 Itga2 Itga2 Pik3ca Pik3ca Birc7 Birc7 Lamb3 Lamb3 Akt2 Akt2 Bcl2l1 Bcl2l1 Akt3 Akt3 Ikbkg Ikbkg Rxra Rxra ENSDORP00000016157 ENSDORP00000016157 Cks1b Cks1b Traf6 Traf6 Lama5 Lama5 Traf1 Traf1 Bax Bax Ccne2 Ccne2 Lamc2 Lamc2 Lamc3 Lamc3 Rxrg Rxrg Mff Mff Rxrb Rxrb E2f1 E2f1 Nos2 Nos2 Traf4 Traf4 Cdkn1b Cdkn1b Lamb1 Lamb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Traf3TNF receptor-associated factor. (549 aa)
Itga3Integrin alpha-3; Belongs to the integrin alpha chain family. (1050 aa)
Skp2S-phase kinase-associated protein 2 isoform X1. (424 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
Col4a6Collagen alpha-6(IV) chain. (1663 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
Col4a4Collagen alpha-4(IV) chain. (1683 aa)
Gadd45gGrowth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa)
Lama4Laminin subunit alpha-4. (1819 aa)
Col4a2Collagen alpha-2(IV) chain. (1643 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (573 aa)
XiapE3 ubiquitin-protein ligase XIAP isoform X1. (495 aa)
Lama1Laminin subunit alpha-1. (3037 aa)
Gadd45aGrowth arrest and DNA damage-inducible protein GADD45 alpha. (166 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
ENSDORP00000026425annotation not available (105 aa)
ENSDORP00000026359annotation not available (202 aa)
ENSDORP00000025725annotation not available (105 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
Fn1Fibronectin. (321 aa)
Cks2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (57 aa)
Secisbp2Selenocysteine insertion sequence-binding protein 2 isoform X1. (853 aa)
Cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
ENSDORP00000024829annotation not available (81 aa)
Bak1Bcl-2 homologous antagonist/killer. (211 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
E2f3Transcription factor E2F3 isoform X1. (461 aa)
ENSDORP00000023006annotation not available (100 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
Col4a1Collagen alpha-1(IV) chain. (1669 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Cdkn2bCyclin-dependent kinase 4 inhibitor B-like. (139 aa)
ENSDORP00000021562annotation not available (78 aa)
ENSDORP00000021143annotation not available (105 aa)
RarbRetinoic acid receptor beta isoform X1. (448 aa)
Lama2Laminin subunit alpha-2. (3099 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
ENSDORP00000019550annotation not available (99 aa)
Rb1Retinoblastoma-associated protein isoform X1. (926 aa)
Gadd45bGrowth arrest and DNA damage-inducible protein GADD45 beta. (160 aa)
MaxProtein max isoform X1. (160 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (1047 aa)
Gm10053Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
Cdk2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
ENSDORP00000016209annotation not available (179 aa)
Ccnd1G1/S-specific cyclin-D1. (156 aa)
Lamc1Laminin subunit gamma-1. (1563 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
E2f2Transcription factor E2F2. (308 aa)
CyctCytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
4921507P07RikUncharacterized protein C7orf31 homolog. (560 aa)
Traf2TNF receptor-associated factor. (484 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Itga6Integrin alpha-6; Belongs to the integrin alpha chain family. (1075 aa)
Itga2bIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (891 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Lama3Laminin subunit alpha-3. (1719 aa)
Lamb2Laminin subunit beta-2. (1800 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
FhitBis(5'-adenosyl)-triphosphatase. (150 aa)
Ddb2DNA damage-binding protein 2 isoform X1. (428 aa)
PolkDNA polymerase kappa isoform X1. (546 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Ccne1G1/S-specific cyclin-E1; Belongs to the cyclin family. (413 aa)
Zbtb17Zinc finger and BTB domain-containing protein 17. (678 aa)
PtenPhosphatase and tensin homolog. (396 aa)
Apaf1Apoptotic protease-activating factor 1. (1107 aa)
Itga2Integrin alpha-2; Belongs to the integrin alpha chain family. (1167 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Birc7Baculoviral IAP repeat-containing 7 (livin). (252 aa)
Lamb3Laminin subunit beta-3. (1172 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Bcl2l1Bcl-2-like protein 1 isoform X1. (234 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
RxraRetinoic acid receptor RXR-alpha. (457 aa)
ENSDORP00000016157annotation not available (79 aa)
Cks1bCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (529 aa)
Lama5Laminin subunit alpha-5. (3481 aa)
Traf1TNF receptor-associated factor. (408 aa)
BaxApoptosis regulator BAX. (143 aa)
Ccne2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa)
Lamc2Laminin subunit gamma-2. (1183 aa)
Lamc3Laminin subunit gamma-3. (1286 aa)
RxrgRetinoic acid receptor RXR-gamma isoform X1. (463 aa)
MffMitochondrial fission factor isoform X4. (291 aa)
RxrbRetinoic acid receptor RXR-beta isoform X2. (526 aa)
E2f1Transcription factor E2F1. (436 aa)
Nos2Nitric oxide synthase; Produces nitric oxide (NO). (1149 aa)
Traf4TNF receptor-associated factor. (470 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (106 aa)
Lamb1Laminin subunit beta-1. (1815 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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