STRINGSTRING
Sp1 Sp1 Slc44a4 Slc44a4 Pik3r3 Pik3r3 Eif4ebp1 Eif4ebp1 Pip5k1b Pip5k1b Chka Chka Egfr Egfr LOC105981182 LOC105981182 Mapk1 Mapk1 Slc5a7 Slc5a7 Slc44a1 Slc44a1 Pld2 Pld2 Pip5k1c Pip5k1c Lypla1 Lypla1 Slc44a2 Slc44a2 Pdgfra Pdgfra Pik3r1 Pik3r1 Pld1 Pld1 Sos2 Sos2 Rps6kb2 Rps6kb2 Kras Kras Pdgfb Pdgfb LOC106000559 LOC106000559 Plpp2 Plpp2 Nras Nras Pla2g4a Pla2g4a Pip5k1a Pip5k1a ENSDORP00000023223 ENSDORP00000023223 Dgka Dgka Pdgfrb Pdgfrb Pcyt1b Pcyt1b Hras Hras Mapk8 Mapk8 Wasf1 Wasf1 Pik3ca Pik3ca Slc44a3 Slc44a3 Rac2 Rac2 Dgkq Dgkq Slc22a3 Slc22a3 Slc22a2 Slc22a2 Dgkz Dgkz Wasf2 Wasf2 Dgkk Dgkk Plpp1 Plpp1 Rhebl1 Rhebl1 Pik3cb Pik3cb Dgki Dgki Akt1 Akt1 Slc22a5 Slc22a5 Slc22a4 Slc22a4 Pla2g4f Pla2g4f Pla2g4d Pla2g4d Dgkh Dgkh Hif1a Hif1a Mast3 Mast3 Dgke Dgke Gpcpd1 Gpcpd1 Chpt1 Chpt1 Prkcg Prkcg Mapk9 Mapk9 Mtor Mtor Pdgfa Pdgfa Mapk3 Mapk3 Wasf3 Wasf3 Chkb Chkb Dgkb Dgkb Sos1 Sos1 Pla2g4e Pla2g4e Map2k1 Map2k1 Map2k2 Map2k2 Egf Egf Ralgds Ralgds Was Was Fos Fos Plpp3 Plpp3 Pcyt1a Pcyt1a Akt2 Akt2 Akt3 Akt3 Grb2 Grb2 Mapk10 Mapk10 Prkca Prkca Rheb Rheb Pdgfc Pdgfc Kras-2 Kras-2 LOC106001479 LOC106001479 Slc22a1 Slc22a1 Csde1 Csde1 Slc44a5 Slc44a5 Pdpk1 Pdpk1 Plcg1 Plcg1 Tsc1 Tsc1 Pik3cd Pik3cd Dgkd Dgkd Tsc2 Tsc2 Dgkg Dgkg Rac1 Rac1 Prkcb Prkcb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sp1Transcription factor Sp1. (786 aa)
Slc44a4Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (709 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
Pip5k1bPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X3. (540 aa)
ChkaCholine kinase alpha isoform X1. (340 aa)
EgfrReceptor protein-tyrosine kinase. (1215 aa)
LOC105981182Phospholipase A2. (787 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
Slc5a7High affinity choline transporter 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
Slc44a1Choline transporter-like protein 1 isoform X1; Belongs to the CTL (choline transporter-like) family. (718 aa)
Pld2Phospholipase. (934 aa)
Pip5k1cLOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (976 aa)
Lypla1Acyl-protein thioesterase 1. (230 aa)
Slc44a2Choline transporter-like protein 2; Belongs to the CTL (choline transporter-like) family. (618 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Pld1Phospholipase. (968 aa)
Sos2Son of sevenless homolog 2. (1320 aa)
Rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
KrasKirsten rat sarcoma viral oncogene homolog. (163 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
Plpp2Lipid phosphate phosphohydrolase 2. (298 aa)
NrasGTPase NRas. (189 aa)
Pla2g4aPhospholipase A2. (750 aa)
Pip5k1aPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha. (569 aa)
ENSDORP00000023223annotation not available (74 aa)
DgkaDiacylglycerol kinase. (642 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
Pcyt1bCholine-phosphate cytidylyltransferase B. (368 aa)
HrasGTPase HRas isoform X1. (192 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Wasf1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Slc44a3Choline transporter-like protein 3; Belongs to the CTL (choline transporter-like) family. (573 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (184 aa)
DgkqDiacylglycerol kinase. (898 aa)
Slc22a3Solute carrier family 22 member 3. (509 aa)
Slc22a2Solute carrier family 22 member 2 isoform X1. (554 aa)
DgkzDiacylglycerol kinase. (707 aa)
Wasf2wiskott-Aldrich syndrome protein family member 2. (496 aa)
DgkkDiacylglycerol kinase. (1273 aa)
Plpp1Lipid phosphate phosphohydrolase 1 isoform X2. (285 aa)
Rhebl1GTPase RhebL1. (176 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
DgkiDiacylglycerol kinase. (901 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Slc22a5Solute carrier family 22 member 5. (557 aa)
Slc22a4Solute carrier family 22 member 4. (553 aa)
Pla2g4fPhospholipase A2, group IVF. (843 aa)
Pla2g4dPhospholipase A2. (708 aa)
DgkhDiacylglycerol kinase. (1145 aa)
Hif1aHypoxia-inducible factor 1-alpha. (246 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
DgkeDiacylglycerol kinase. (527 aa)
Gpcpd1Glycerophosphocholine phosphodiesterase GPCPD1 isoform X1. (672 aa)
Chpt1Cholinephosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (396 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (210 aa)
Mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
Wasf3wiskott-Aldrich syndrome protein family member 3. (503 aa)
ChkbCholine/ethanolamine kinase. (378 aa)
DgkbDiacylglycerol kinase. (795 aa)
Sos1Son of sevenless homolog 1. (1301 aa)
Pla2g4ePhospholipase A2. (866 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (375 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (664 aa)
RalgdsRal guanine nucleotide dissociation stimulator isoform X2. (855 aa)
Waswiskott-Aldrich syndrome protein. (503 aa)
FosProto-oncogene c-Fos. (380 aa)
Plpp3Lipid phosphate phosphohydrolase 3. (312 aa)
Pcyt1aCholine-phosphate cytidylyltransferase A. (367 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
RhebGTP-binding protein Rheb. (112 aa)
PdgfcPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (344 aa)
Kras-2GTPase KRas isoform X4. (189 aa)
LOC106001479Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (492 aa)
Slc22a1Solute carrier family 22 member 1. (554 aa)
Csde1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Slc44a5Choline transporter-like protein 5; Belongs to the CTL (choline transporter-like) family. (706 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X1. (552 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
Tsc1Hamartin isoform X1. (1121 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
DgkdDiacylglycerol kinase. (1133 aa)
Tsc2Tuberin isoform X1. (1809 aa)
DgkgDiacylglycerol kinase. (756 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
PrkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (621 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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