STRINGSTRING
Itga4 Itga4 Igf1 Igf1 Itgb8 Itgb8 Adcy5 Adcy5 Sgcd Sgcd Atp2a1 Atp2a1 Adcy1 Adcy1 Cacna2d1 Cacna2d1 Itga2 Itga2 Cacnb2 Cacnb2 Tpm1 Tpm1 Tgfb1 Tgfb1 Tnnc1 Tnnc1 Actrt2 Actrt2 Tgfb2 Tgfb2 Gnas Gnas Ryr2 Ryr2 Itga6 Itga6 Cacna1d Cacna1d Adcy6 Adcy6 Itgb6 Itgb6 Cacng5 Cacng5 Sgcg Sgcg Itga2b Itga2b Itga8 Itga8 LOC105984756 LOC105984756 Tnnt2 Tnnt2 Adcy8 Adcy8 Adcy3 Adcy3 Itgb1 Itgb1 Cacna2d2 Cacna2d2 Itga5 Itga5 Myh4 Myh4 Myh2 Myh2 Itga10 Itga10 Actl7b Actl7b Actl7a Actl7a Myh15 Myh15 Sgcb Sgcb Slc8a2 Slc8a2 Atp2a3 Atp2a3 Adcy7 Adcy7 Cacng2 Cacng2 Lama1 Lama1 Adcy2 Adcy2 Cacng4 Cacng4 LOC106002210 LOC106002210 Agt Agt Adcy4 Adcy4 Cacna2d3 Cacna2d3 Tnf Tnf Cacnb3 Cacnb3 Tgfb3 Tgfb3 Itga9 Itga9 Myh6 Myh6 Myh7 Myh7 Cacng3 Cacng3 Itga3 Itga3 Sgca Sgca Utrn Utrn Myh3 Myh3 Itga7 Itga7 Slc39a12 Slc39a12 Prkaca Prkaca Cacna1s Cacna1s Cacnb1 Cacnb1 Itgb3 Itgb3 Adcy9 Adcy9 Cacng6 Cacng6 Atp2a2 Atp2a2 Ptrhd1 Ptrhd1 ENSDORP00000017709 ENSDORP00000017709 Tnnt3 Tnnt3 Lmna Lmna Itgav Itgav Tnnt1 Tnnt1 Itga1 Itga1 Pln Pln Tpm2 Tpm2 Cacnb4 Cacnb4 Prkacb Prkacb Dag1 Dag1 Lama2 Lama2 Cacna1c Cacna1c ENSDORP00000020304 ENSDORP00000020304 Cacng8 Cacng8 Tpm4 Tpm4 Dmd Dmd Actb Actb Slc8a3 Slc8a3 Tnni3 Tnni3 Cacng7 Cacng7 LOC105994343 LOC105994343 Myl2 Myl2 Cacna1f Cacna1f Myh1 Myh1 Slc8a1 Slc8a1 ENSDORP00000024730 ENSDORP00000024730 Itgb5 Itgb5 ENSDORP00000025770 ENSDORP00000025770 Itgb4 Itgb4 LOC105993437 LOC105993437 Itga11 Itga11 ENSDORP00000026390 ENSDORP00000026390 Mybpc3 Mybpc3 Actl11 Actl11 Myl3 Myl3 Myh8 Myh8 Emd Emd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Itga4Integrin alpha-4; Belongs to the integrin alpha chain family. (1032 aa)
Igf1Insulin-like growth factor I isoform X2. (130 aa)
Itgb8Integrin beta; Belongs to the integrin beta chain family. (737 aa)
Adcy5Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1186 aa)
SgcdDelta-sarcoglycan. (289 aa)
Atp2a1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1069 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (937 aa)
Cacna2d1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1079 aa)
Itga2Integrin alpha-2; Belongs to the integrin alpha chain family. (1167 aa)
Cacnb2Voltage-dependent L-type calcium channel subunit beta-2 isoform X2. (580 aa)
Tpm1Tropomyosin alpha-1 chain isoform X4; Belongs to the tropomyosin family. (326 aa)
Tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (130 aa)
Tnnc1Troponin C, slow skeletal and cardiac muscles. (161 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (443 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (394 aa)
Ryr2Ryanodine receptor 2. (4946 aa)
Itga6Integrin alpha-6; Belongs to the integrin alpha chain family. (1075 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2039 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Itgb6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
Cacng5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
SgcgGamma-sarcoglycan. (291 aa)
Itga2bIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (891 aa)
Itga8Integrin alpha-8; Belongs to the integrin alpha chain family. (1063 aa)
LOC105984756Tropomyosin alpha-3 chain-like. (145 aa)
Tnnt2Troponin T, cardiac muscle isoform X1. (231 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Cacna2d2Voltage-dependent calcium channel subunit alpha-2/delta-2. (1080 aa)
Itga5Integrin alpha-5; Belongs to the integrin alpha chain family. (1057 aa)
Myh4Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
Myh2Myosin-2 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa)
Itga10Integrin alpha-10; Belongs to the integrin alpha chain family. (1034 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (418 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (439 aa)
Myh15Myosin-15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1925 aa)
SgcbBeta-sarcoglycan. (318 aa)
Slc8a2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (776 aa)
Atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1009 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
Cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (295 aa)
Lama1Laminin subunit alpha-1. (3037 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (854 aa)
Cacng4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
LOC106002210Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (120 aa)
AgtAngiotensinogen; Belongs to the serpin family. (473 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
Cacna2d3Voltage-dependent calcium channel subunit alpha-2/delta-3. (756 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
Cacnb3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (485 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Itga9Integrin alpha-9; Belongs to the integrin alpha chain family. (999 aa)
Myh6Myosin-6-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1774 aa)
Myh7Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
Cacng3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
Itga3Integrin alpha-3; Belongs to the integrin alpha chain family. (1050 aa)
SgcaAlpha-sarcoglycan. (390 aa)
UtrnUtrophin. (981 aa)
Myh3Myosin-3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
Itga7Integrin alpha-7; Belongs to the integrin alpha chain family. (1178 aa)
Slc39a12Zinc transporter ZIP12 isoform X2. (685 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1864 aa)
Cacnb1Voltage-dependent L-type calcium channel subunit beta-1. (677 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (766 aa)
Adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1330 aa)
Cacng6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
Atp2a2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (986 aa)
Ptrhd1Putative peptidyl-tRNA hydrolase PTRHD1. (146 aa)
ENSDORP00000017709annotation not available (94 aa)
Tnnt3Troponin T, fast skeletal muscle. (274 aa)
LmnaLamin; Belongs to the intermediate filament family. (663 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (1047 aa)
Tnnt1Troponin T, slow skeletal muscle isoform X1. (263 aa)
Itga1Integrin alpha-1; Belongs to the integrin alpha chain family. (1160 aa)
PlnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
Tpm2Tropomyosin beta chain; Belongs to the tropomyosin family. (284 aa)
Cacnb4Voltage-dependent L-type calcium channel subunit beta-4. (333 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (351 aa)
Dag1Dystroglycan. (891 aa)
Lama2Laminin subunit alpha-2. (3099 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1179 aa)
ENSDORP00000020304annotation not available (160 aa)
Cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (415 aa)
Tpm4Tropomyosin alpha-4 chain; Belongs to the tropomyosin family. (257 aa)
DmdDystrophin isoform X3. (617 aa)
ActbActin, cytoplasmic 1. (375 aa)
Slc8a3Sodium/calcium exchanger 3 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (926 aa)
Tnni3Troponin I, cardiac muscle isoform X2. (211 aa)
Cacng7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
LOC105994343Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (224 aa)
Myl2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (144 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (247 aa)
Myh1Myosin-1 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1942 aa)
Slc8a1Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (970 aa)
ENSDORP00000024730annotation not available (305 aa)
Itgb5Integrin beta; Belongs to the integrin beta chain family. (739 aa)
ENSDORP00000025770annotation not available (300 aa)
Itgb4Integrin beta. (1830 aa)
LOC105993437LOW QUALITY PROTEIN: dystrophin-like. (776 aa)
Itga11Integrin alpha-11; Belongs to the integrin alpha chain family. (1142 aa)
ENSDORP00000026390annotation not available (153 aa)
Mybpc3Myosin-binding protein C, cardiac-type. (1320 aa)
Actl11Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa)
Myl3Myosin light chain 3. (197 aa)
Myh8Myosin-8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
EmdEmerin. (255 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (26%) [HD]