STRINGSTRING
Gsto1 Gsto1 Ikbkg Ikbkg ENSDORP00000027628 ENSDORP00000027628 Akt3 Akt3 Cav1 Cav1 Cav2 Cav2 Actl11 Actl11 Gstp3 Gstp3 Map2k6 Map2k6 Il1r1 Il1r1 LOC105983409 LOC105983409 Akt2 Akt2 Cav3 Cav3 Fos Fos Nppc Nppc LOC105997812 LOC105997812 Ncf2 Ncf2 LOC105997442 LOC105997442 Pecam1 Pecam1 Mapk8 Mapk8 Edn1 Edn1 Sumo1 Sumo1 ENSDORP00000025047 ENSDORP00000025047 Sumo3 Sumo3 Mgst1 Mgst1 LOC105987731 LOC105987731 Txn Txn Mapk14 Mapk14 Sdc4 Sdc4 Trp53 Trp53 Sumo2 Sumo2 Nox1 Nox1 LOC105987800 LOC105987800 Arhgef2 Arhgef2 Nos3 Nos3 ENSDORP00000022835 ENSDORP00000022835 LOC105997443 LOC105997443 LOC105993766 LOC105993766 LOC106001870 LOC106001870 Map2k5 Map2k5 LOC105988088 LOC105988088 Actb Actb Nfe2l2 Nfe2l2 LOC106000559 LOC106000559 Pdgfb Pdgfb Ncf1 Ncf1 Gsta4 Gsta4 ENSDORP00000021275 ENSDORP00000021275 Calm3 Calm3 ENSDORP00000020658 ENSDORP00000020658 ENSDORP00000020585 ENSDORP00000020585 Gstt4 Gstt4 Vcam1 Vcam1 Pik3r1 Pik3r1 Gstt3 Gstt3 Ptk2 Ptk2 LOC105987815 LOC105987815 Cyba Cyba LOC106001529 LOC106001529 LOC105997437 LOC105997437 ENSDORP00000018748 ENSDORP00000018748 Calml4 Calml4 Mef2c Mef2c Sdc2 Sdc2 Gstm7 Gstm7 Itgav Itgav Rhoa Rhoa Il1a Il1a Gpc1 Gpc1 LOC106002211 LOC106002211 Txn2 Txn2 Calm1 Calm1 ENSDORP00000017128 ENSDORP00000017128 Noxa1 Noxa1 Pttg1ip Pttg1ip Dusp1 Dusp1 Pik3r3 Pik3r3 Mapk7 Mapk7 Itgb3 Itgb3 Calml3 Calml3 Mef2a Mef2a Sqstm1 Sqstm1 Sdc1 Sdc1 Mapk13 Mapk13 LOC105987814 LOC105987814 Acvr2a Acvr2a LOC105997418 LOC105997418 Rac1 Rac1 Hmox1 Hmox1 Prkaa1 Prkaa1 Keap1 Keap1 Acvr1 Acvr1 Map3k7 Map3k7 Mmp2 Mmp2 Ikbkb Ikbkb Rela Rela Tnf Tnf Txndc8 Txndc8 Pik3cd Pik3cd ENSDORP00000011621 ENSDORP00000011621 Chuk Chuk Hsp90ab1 Hsp90ab1 Ass1 Ass1 Bmp4 Bmp4 LOC105997438 LOC105997438 Mapk10 Mapk10 Calm2 Calm2 Il1b Il1b Bmpr1a Bmpr1a Prkaa2 Prkaa2 Pik3ca Pik3ca Bmpr2 Bmpr2 Rac2 Rac2 Map2k7 Map2k7 Mgst2 Mgst2 Gsto2 Gsto2 Plat Plat Acvr2b Acvr2b Actl7a Actl7a Actl7b Actl7b Nfkb1 Nfkb1 Gstt1 Gstt1 Kdr Kdr Pik3cb Pik3cb Trpv4 Trpv4 Akt1 Akt1 Itga2b Itga2b Hsp90aa1 Hsp90aa1 Hsp90b1 Hsp90b1 Mgst3 Mgst3 Mast3 Mast3 Mapk9 Mapk9 Actrt2 Actrt2 Pdgfa Pdgfa Rhoc Rhoc Pias4 Pias4 LOC105997419 LOC105997419 LOC105989276 LOC105989276 Bcl2 Bcl2 Mapk12 Mapk12 Map3k5 Map3k5 Il1r2 Il1r2 Gstm3 Gstm3 Nqo1 Nqo1 Bmpr1b Bmpr1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gsto1Glutathione S-transferase omega-1. (241 aa)
IkbkgNF-kappa-B essential modulator isoform X3. (410 aa)
ENSDORP00000027628annotation not available (72 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
Actl11Uncharacterized protein LOC105994564; Belongs to the actin family. (1215 aa)
Gstp3Glutathione S-transferase P-like. (209 aa)
Map2k6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
Il1r1Interleukin-1 receptor type 1 isoform X1. (574 aa)
LOC105983409Small ubiquitin-related modifier 2-like. (74 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
FosProto-oncogene c-Fos. (380 aa)
NppcC-type natriuretic peptide. (126 aa)
LOC105997812LOW QUALITY PROTEIN: uncharacterized protein LOC105997812. (91 aa)
Ncf2Neutrophil cytosol factor 2 isoform X1. (526 aa)
LOC105997442Glutathione S-transferase. (218 aa)
Pecam1Platelet endothelial cell adhesion molecule. (715 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Edn1Endothelin-1-like isoform X1. (202 aa)
Sumo1Small ubiquitin-related modifier 1. (83 aa)
ENSDORP00000025047annotation not available (79 aa)
Sumo3Small ubiquitin-related modifier 3. (118 aa)
Mgst1Microsomal glutathione S-transferase 1. (47 aa)
LOC105987731Uncharacterized protein LOC105987731. (169 aa)
TxnThioredoxin; Belongs to the thioredoxin family. (105 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Sdc4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (204 aa)
Trp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
Sumo2Small ubiquitin-related modifier. (95 aa)
Nox1NADPH oxidase 1 isoform X1. (567 aa)
LOC105987800Vascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (185 aa)
Arhgef2Rho guanine nucleotide exchange factor 2 isoform X1. (979 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1201 aa)
ENSDORP00000022835annotation not available (193 aa)
LOC105997443Glutathione S-transferase Mu 1-like. (148 aa)
LOC105993766Uncharacterized protein LOC105993766. (95 aa)
LOC106001870Small ubiquitin-related modifier 2-like. (100 aa)
Map2k5Dual specificity mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (439 aa)
LOC105988088Small ubiquitin-related modifier. (95 aa)
ActbActin, cytoplasmic 1. (375 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (592 aa)
LOC106000559Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
Ncf1Neutrophil cytosol factor 1 isoform X4. (396 aa)
Gsta4Glutathione S-transferase A4-like. (204 aa)
ENSDORP00000021275annotation not available (206 aa)
Calm3Calmodulin 3. (149 aa)
ENSDORP00000020658annotation not available (108 aa)
ENSDORP00000020585annotation not available (80 aa)
Gstt4Glutathione S-transferase theta-4. (216 aa)
Vcam1Vascular cell adhesion protein 1. (739 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Gstt3Glutathione S-transferase theta-1-like; Belongs to the GST superfamily. (240 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
LOC105987815Glutathione S-transferase A1; Belongs to the GST superfamily. (221 aa)
CybaCytochrome b-245 light chain. (176 aa)
LOC106001529Mitogen-activated protein kinase kinase kinase 7-like. (538 aa)
LOC105997437Glutathione S-transferase. (218 aa)
ENSDORP00000018748annotation not available (67 aa)
Calml4Calmodulin-like protein 4 isoform X1. (153 aa)
Mef2cMyocyte-specific enhancer factor 2C isoform X5. (483 aa)
Sdc2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
Gstm7Glutathione S-transferase Mu 2; Belongs to the GST superfamily. (218 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (1047 aa)
RhoaTransforming protein RhoA. (193 aa)
Il1aInterleukin-1; Belongs to the IL-1 family. (270 aa)
Gpc1Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (548 aa)
LOC106002211Small ubiquitin-related modifier. (89 aa)
Txn2Thioredoxin, mitochondrial. (64 aa)
Calm1Calmodulin 1. (149 aa)
ENSDORP00000017128annotation not available (72 aa)
Noxa1NADPH oxidase activator 1 isoform X1. (418 aa)
Pttg1ipPituitary tumor-transforming gene 1 protein-interacting protein. (138 aa)
Dusp1Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (244 aa)
Pik3r3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
Mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (813 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (766 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Mef2aMyocyte-specific enhancer factor 2A isoform X2. (496 aa)
Sqstm1Sequestosome-1. (433 aa)
Sdc1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (286 aa)
Mapk13Mitogen-activated protein kinase. (334 aa)
LOC105987814Glutathione S-transferase A3-like. (170 aa)
Acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
LOC105997418Glutathione S-transferase. (196 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (187 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (285 aa)
Prkaa1Non-specific serine/threonine protein kinase. (538 aa)
Keap1Kelch-like ECH-associated protein 1. (619 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
Map3k7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (596 aa)
Mmp272 kDa type IV collagenase. (126 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta. (732 aa)
RelaTranscription factor p65 isoform X1. (236 aa)
TnfTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (220 aa)
Txndc8Thioredoxin domain-containing protein 8. (137 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ENSDORP00000011621annotation not available (186 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
Hsp90ab1Heat shock protein HSP 90-beta. (723 aa)
Ass1Argininosuccinate synthase. (412 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
LOC105997438Glutathione S-transferase. (213 aa)
Mapk10Mitogen-activated protein kinase. (486 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (149 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Prkaa2Non-specific serine/threonine protein kinase. (549 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (933 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (184 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
Mgst2Microsomal glutathione S-transferase 2. (123 aa)
Gsto2Glutathione S-transferase omega-2; Belongs to the GST superfamily. (245 aa)
PlatPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
Acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (303 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (439 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (418 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
Gstt1Glutathione S-transferase theta-1-like isoform X1; Belongs to the GST superfamily. (240 aa)
KdrVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1352 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Trpv4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (869 aa)
Akt1Non-specific serine/threonine protein kinase. (188 aa)
Itga2bIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (891 aa)
Hsp90aa1Heat shock protein HSP 90-alpha. (733 aa)
Hsp90b1Endoplasmin. (804 aa)
Mgst3Microsomal glutathione S-transferase 3. (164 aa)
Mast3Microtubule associated serine/threonine kinase 3. (71 aa)
Mapk9Mitogen-activated protein kinase. (382 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (210 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Pias4E3 SUMO-protein ligase PIAS4. (517 aa)
LOC105997419Glutathione S-transferase. (189 aa)
LOC105989276Glutathione S-transferase P; Belongs to the GST superfamily. (210 aa)
Bcl2Apoptosis regulator Bcl-2. (196 aa)
Mapk12Mitogen-activated protein kinase. (351 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5. (144 aa)
Il1r2Interleukin-1 receptor type 2 isoform X1. (390 aa)
Gstm3Glutathione S-transferase Mu 3; Belongs to the GST superfamily. (226 aa)
Nqo1NAD(P)H dehydrogenase [quinone] 1. (277 aa)
Bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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