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SCO0136 SCO0136 SCO0137 SCO0137 SCO0338 SCO0338 SCO0339 SCO0339 SCO0434 SCO0434 SCO0578 SCO0578 SCO0579 SCO0579 SCO0616 SCO0616 SCO0617 SCO0617 SCO0782 SCO0782 SCO0798 SCO0798 SCO0851 SCO0851 SCO0852 SCO0852 SCO0975 SCO0975 SCO0982 SCO0982 SCO0983 SCO0983 SCO1077 SCO1077 SCO1117 SCO1117 SCO1169 SCO1169 SCO1170 SCO1170 SCO1171 SCO1171 SCO1172 SCO1172 SCO1173 SCO1173 SCO1192 SCO1192 SCO1214 SCO1214 SCO1224 SCO1224 SCO1225 SCO1225 SCO1390 SCO1390 SCO1391 SCO1391 SCO1464 SCO1464 SCO1679 SCO1679 SCO1897 SCO1897 SCO1935 SCO1935 SCO1936 SCO1936 SCO1937 SCO1937 SCO1939 SCO1939 SCO1942 SCO1942 SCO1945 SCO1945 SCO1946 SCO1946 SCO1947 SCO1947 SCO1957 SCO1957 SCO2014 SCO2014 SCO2119 SCO2119 SCO2145 SCO2145 SCO2298 SCO2298 SCO2401 SCO2401 SCO2462 SCO2462 SCO2627 SCO2627 SCO2789 SCO2789 SCO2905 SCO2905 SCO2906 SCO2906 SCO2907 SCO2907 SCO3096 SCO3096 SCO3122 SCO3122 SCO3123 SCO3123 SCO3196 SCO3196 SCO3197 SCO3197 SCO3198 SCO3198 SCO3473 SCO3473 SCO3474 SCO3474 SCO3475 SCO3475 SCO3476 SCO3476 SCO3478 SCO3478 SCO3494 SCO3494 SCO3495 SCO3495 SCO3649 SCO3649 SCO3877 SCO3877 SCO4209 SCO4209 SCO4283 SCO4283 SCO4284 SCO4284 SCO4285 SCO4285 SCO4736 SCO4736 SCO4740 SCO4740 SCO4920 SCO4920 SCO4988 SCO4988 SCO5047 SCO5047 SCO5059 SCO5059 SCO5236 SCO5236 SCO5423 SCO5423 SCO5426 SCO5426 SCO5515 SCO5515 SCO5841 SCO5841 SCO5852 SCO5852 SCO6110 SCO6110 SCO6260 SCO6260 SCO6466 SCO6466 SCO6497 SCO6497 SCO6658 SCO6658 SCO6659 SCO6659 SCO6661 SCO6661 SCO6662 SCO6662 SCO6663 SCO6663 SCO6818 SCO6818 SCO7040 SCO7040 SCO7443 SCO7443 SCO7511 SCO7511 SCO7568 SCO7568 SCO7629 SCO7629 SCO7638 SCO7638
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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Predicted Interactions
gene neighborhood
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SCO0136SCJ21.17c, probable integral membrane protein, len: 516 aa; similar to SGAT_ECOLI putative transport protein SGAT (484 aa), fasta scores; opt: 339 z-score: 341.6 E(): 1.1e-11, 28.5% identity in 414 aa overlap. Contains probable membrane spanning hydrophobic domains. (516 aa)
SCO0137Possible sugar-transport protein; SCJ21.18c, unknown, partial CDS, len >170 aa; SCJ33.01c, putative sugar-transport protein, partial CDS, len: > 138 aa. Similar to many e.g. Escherichia coli SW: PTXA_ECOLI (EMBL; U14003) unknown pentitol phosphotransferase enzyme II, A component (EC 2.7.1.69) (154 aa), fasta scores opt: 313 z-score: 403.6 E(): 4.1e-15 38.3% identity in 133 aa overlap. Overlaps with and extends into CDS SCJ21.18c. Contains a Pfam match to entry PF00359 PTS_EIIA_2, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. (266 aa)
SCO0338SCF12.17c, possible dehydrogenase, len: 179 aa; similar to the C-terminal many proposed glucose-6-phosphate dehydrogenase eg. TR:AAD36231 (EMBL:AE001772) from Thermotoga maritima (496 aa) fasta scores; opt: 314, z-score: 381.8, E(): 6.5e-14, (42.5% identity in 146 aa overlap). Contains Pfam match to entry PF00479 G6PD, Glucose-6-phosphate dehydrogenase. (179 aa)
SCO0339SCF12.18, possible dehydrogenase, len: 189 aa; similar to a region from many proposed dehydrogenases e.g. SW:SERA_METJA D-3-phosphoglycerate dehydrogenase from Methanococcus jannaschii (524 aa) fasta scores; opt: 415, z-score: 508.1, E(): 6e-21, 40.8% identity in 179 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases. (189 aa)
SCO0434SCF51A.12, malX, sugar phosphotransferase, len: 549 aa. Highly similar to Escherichia coli SW:PTOA_ECOLI (EMBL; M60722) PTS system, maltose and glucose-specific II ABC component (maltose and glucose-permease II ABC component) (phosphotransferase enzyme II, ABC component) (EC 2.7.1.69) (523 aa), fasta scores opt: 1852 z-score: 2064.1 E():0 59.5% identity in 543 aa overlap. Contains a Pfam match to entry PF00367 PTS_EIIB, phosphotransferase system, EIIB and a Prosite hit to PS01035 PTS EIIB domains cysteine phosphorylation site signature. Contains multiple possible membrane spanning hydr [...] (549 aa)
SCO0578SCF55.02c, possible triosephosphate isomerase, len: 259 aa; similar to SW:TPIS_MYCTU (EMBL:Z95844) Mycobacterium tuberculosis triosephosphate isomerase (EC 5.3.1.1) TpiA, 261 aa; fasta scores: opt: 437 z-score: 490.8 E(): 5.8e-20; 38.9% identity in 221 aa overlap. Contains match to Pfam entry PF00121 TIM, Triosephosphate isomerase. (259 aa)
SCO0579Putative ribose 5-phosphate isomerase; SCF55.03c, possible sugar-phosphate isomerase, len: 170 aa; similar to SW:RPIB_ECOLI (EMBL:X82203) Escherichia coli ribose 5-phosphate isomerase B (EC 5.3.1.6) (phosphoriboisomerase B) RpiB, 149 aa; fasta scores: opt: 299 z-score: 364.4 E(): 6.3e-13; 38.5% identity in 148 aa overlap. (170 aa)
SCO0616SCF55.40c, hypothetical protein, len: 791 aa; similar to various hypothetical proteins, e.g. SW:YK06_MYCTU (EMBL:Z74025) Mycobacterium tuberculosis hypothetical 145.8 KD protein RV2006, 1327 aa; fasta scores: opt: 2445 z-score: 2870.6 E(): 0; 50.0% identity in 790 aa overlap. (791 aa)
SCO0617SCF56.01c, hypothetical protein (partial CDS), len: >634 aa; similar to various hypothetical proteins, e.g. TR:P74690 (EMBL:D90917) Synechocystis sp. hypothetical 92.4 kD protein, 821 aa; fasta scores: opt: 2107 z-score: 2288.7 E(): 0; 58.1% identity in 513 aa overlap; SCF55.41c, hypothetical protein, len: 210 aa; similar to various hypothetical proteins, e.g. TR:P74690 (EMBL:D90917) Synechocystis sp. (strain PCC 6803) hypothetical 92.4 KD protein, 821 aa; fasta scores: opt: 1405 z-score: 1694.1 E(): 0; 56.1% identity in 328 aa overlap. (817 aa)
SCO07823SCF60.14c, prsA, ribose-phosphate pyrophosphokinase, len: 317 aa; similar to SW:KPRS_SYNP7 (EMBL:D14994) Synechococcus sp. ribose-phosphate pyrophosphokinase (EC 2.7.6.1) PrsA, 331 aa; fasta scores: opt: 795 z-score: 931.4 E(): 0; 42.7% identity in 307 aa overlap. Contains Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain. (317 aa)
SCO0798SCF43.09, putative secreted protein, len: 411 aa. Weakly similar to several proteins of undefined function e.g. Lactococcus lactis TR:O86271(EMBL:AJ001008) OrfB (341 aa), fasta scores opt: 579 z-score: 550.5 E(): 2.8e-23 31.1% identity in 347 aa overlap. (411 aa)
SCO0851SCM2.04c, possible PfkB-family carbohydrate kinase, len: 354 aa. Similar to many carbohydrate kinases including Bacillus subtilis SW:KDGK_BACSU(EMBL:L47838) 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) KdgK (324 aa), fasta scores opt: 497 z-score: 554.8 E(): 1.6e-23 35.0% identity in 311 aa overlap and Bacillus stearothermophilus TR:Q9ZFM1(EMBL:AF098273) 2-keto-3-deoxy-gluconate kinase (314 aa), fasta scores opt: 541 z-score: 603.5 E(): 3.1e-26 36.7% identity in 308 aa overlap. Contains a Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase. (354 aa)
SCO0852SCM2.05c, possible aldolase, len: 210 aa. Similar to Bacillus subtilis SW:ALKH_BACSU (EMBL:L47838) 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) (196 aa), fasta scores opt: 383 z-score: 406.3 E(): 3e-15 38.5% identity in 179 aa overlap. Contains a Pfam match to entry PF01081 Aldolase, KDPG and KHG aldolase. (210 aa)
SCO09756-phosphogluconate 1-dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
SCO0982SCBAC19F3.09, aceA, isocitrate lyase, len: 426 aa: strongly similar to many e.g. SW:O53752 (ACEA_MYCTU) isocitrate lyase from Mycobacterium tuberculosis (428 aa) fasta scores; opt: 2144, Z-score: 2405.5, 74.822% identity (75.000% ungapped) in 421 aa overlap. Contains Pfam matches to entry PF00463 ICL, Isocitrate lyase family and Prosite match to PS00161 Isocitrate lyase signature. (426 aa)
SCO0983SCBAC19F3.10, aceB2, malate synthase, len: 530 aa; strongly similar to many e.g. SW:Q9ZH77 (MASY_STRCL) malate synthase AceB from Streptomyces clavuligerus (541 aa) fasta scores; opt: 1923, Z-score: 2204.2, 58.889% identity (61.390% ungapped) in 540 aa overlap and TR:Q9RKU9 (EMBL:AL132824) malate synthase AceB1 (StAH10.08c) from Streptomyces coelicolor (540 aa) fasta scores; opt: 1930, Z-score: 2212.2, 61.895% identity (63.090% ungapped) in 475 aa overlap. Contains Pfam match to entry PF01274 Malate_synthase, Malate synthase and Prosite match to PS00510 Malate synthase signature. (530 aa)
SCO1077SCG22.23c, probable sugar kinase, len: 317 aa; similar to SW:GLK_BACSU (EMBL:D84432) Bacillus subtilis glucokinase (EC 2.7.1.2) GlcK, 321 aa; fasta scores: opt: 495 z-score: 504.0 E(): 1.3e-20; 31.4% identity in 312 aa overlap. Contains match to Prosite entry PS01125 ROK family signature. (317 aa)
SCO11172SCG38.10c, possible secreted protein, len: 345 aa; similar to TR:Q9RD79 (EMBL:AL136502) Streptomyces coelicolor hypothetical 41.5 kDa protein SCF43.09, 411 aa; fasta scores: opt: 813 z-score: 857.3 E(): 0; 44.1% identity in 358 aa overlap. Contains possible N-terminal region signal peptide sequence. (345 aa)
SCO11692SCG11.03c, xylA, xylose isomerase, len: 387 aa; identical to SW:XYLA_STRRU (EMBL:M73789) Streptomyces rubiginosus xylose isomerase XylA, 387 aa. Contains Pfam match to entry PF00259 Xylose_isom, Xylose isomerase and matches to Prosite entries PS00172 Xylose isomerase signature 1 and PS00173 Xylose isomerase signature 2. (387 aa)
SCO1170Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family. (481 aa)
SCO1171SCG11A.02, possible xylose repressor, len: 402 aa; similar to SW:XYLR_BACSU (EMBL:M27248) Bacillus subtilis xylose repressor xylR, 384 aa; fasta scores: opt: 612 z-score: 642.4 E(): 2.1e-28; 29.4% identity in 381 aa overlap. Contains match to Pfam entry PF00480 ROK, ROK family and a possible helix-turn-helix motif at residues 43..64 (+3.15 SD). (402 aa)
SCO1172SCG11A.03, probable amidase (putative secreted protein), len: 201 aa; similar to SW:AMPD_ECOLI (EMBL:X15237) Escherichia coli anhydro-N-acetylmuramyl-tripeptide amidase AmpD, 183aa; fasta scores: opt: 211 z-score: 267.1 E(): 1.7e-07; 39.5% identity in 114 aa overlap and to Streptomyces coelicolor SC2A11.21c; fasta scores: opt: 674 z-score: 751.6 E(): 0; 50.0% identity in 202 aa overlap. Contains match to Pfam entry PF01510 Amidase_2, N-acetylmuramoyl-L-alanine amidase. Contains possible N-terminal region signal peptide sequence. (201 aa)
SCO1173SCG11A.04, possible transcriptional regulator, len: aa; similar to TR:O31551 (EMBL:Z99108) Bacillus subtilis transcriptional regulator AcoR, 605 aa; fasta scores: opt: 393 z-score: 446.5 E(): 1.7e-17; 34.7% identity in 199 aa overlap. (419 aa)
SCO1192SCG11A.23, hypothetical protein, len:122 aa; similar to various hypothetical proteins, e.g. TR:O53744 (EMBL:AL021933) Mycobacterium tuberculosis hypothetical 17.2 KD protein MTV038.03, 163 aa; fasta scores: opt: 478 z-score: 600.7 E(): 4.4e-26; 66.7% identity in 111 aa overlap. (122 aa)
SCO12146-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (341 aa)
SCO12242SCG58.24c, possible sugar-phosphate isomerase, len: 152 aa; similar to SW:RPIB_ECOLI (EMBL:X82203) Escherichia coli ribose 5-phosphate isomerase B (EC 5.3.1.6) RpiB, 149 aa; fasta scores: opt: 248 z-score: 314.7 E(): 4.6e-10; 36.6% identity in 134 aa overlap. (152 aa)
SCO12252SCG58.25, probable osmoprotectant transporter, len: 504 aa; similar to SW:PROP_ECOLI (EMBL:M83089) Escherichia coli proline/betaine transporter ProP, 500 aa; fasta scores: opt: 1534 z-score: 1728.8 E(): 0; 44.7% identity in 465 aa overlap. Contains Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter and matches to Prosite entries PS00217 Sugar transport proteins signature 2 and PS00216 Sugar transport proteins signature 1. Also contains possible hydrophobic membrane spanning regions. (504 aa)
SCO1390SC1A8A.10, possible PTS system sugar phosphotransferase component IIA, len: 176a; similar to many e.g. TR:BAA82669 (EMBL:AB030569) putative phosphoenolpyruvate:carbohydrate phosphotransferase system family from Streptomyces griseus (149 aa) fasta scores; opt: 897, z-score: 951.7, E(): 0, 88.6% identity in 149 aa overlap and SW:P42015 (PTGA_BACST) PTS system, glucose-specific IIABC component from Bacillus stearothermophilus (324 aa) fasta scores; opt: 359, z-score: 386.4, E(): 4.3e-14, 40.6% identity in 143 aa overlap. Contains Pfam match to entry PF00358 PTS_EIIA_1, phosphoenolpyruvate [...] (149 aa)
SCO1391Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)
SCO1464Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
SCO1679SCI52.21, probable gluconokinase, len: 175 aa; similar to SW:IDNK_ECOLI (EMBL:U14003) Escherichia coli thermosensitive gluconokinase (EC 2.7.1.12) IdnK or GntV or B4268, 187 aa; fasta scores: opt: 434 Z-score: 502.9 bits: 99.6 E(): 2e-20; 43.125% identity in 160 aa overlap. Contains match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop). (175 aa)
SCO1897SCI7.15, probable transcriptional regulator, len: 258 aa; similar to many e.g. SW:GATR_ECOLI galacticol utilisation operon repressor from Escherichia coli (259 aa) fasta scores; opt: 399, z-score: 477.4, E(): 2.9e-19, (33.8% identity in 237 aa overlap). Contains Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family. Also contains a helix-turn-helix motif (+3.53 SD) 26-47aa. (258 aa)
SCO1935Transketolase A; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (695 aa)
SCO1936Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
SCO1937Putative glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
SCO1939Putative 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (261 aa)
SCO1942SCC54.02c, pgi2, glucose-6-phosphate isomerase, len: 551 aa; Member of family of proteins conserved across prokaryotes and eukaryotes. Almost identical to another from Streptomyces coelicolor TR:O88015 (EMBL:AL031107) pgi, glucose-6-phosphate isomerase (550 aa) fasta scores; opt: 3305, z-score: 3849.4, E(): 0, (91.9% identity in 542 aa overlap). Also similar to SW:G6PI_ECOLI pgi, glucose-6-phosphate isomerase from Escherichia coli (549 aa) fasta scores; opt: 1950, z-score: 2271.0, E(): 0, (54.6% identity in 548 aa overlap) and SW:G6PI_MOUSE gpi, glucose-6-phosphate isomerase from Mus m [...] (551 aa)
SCO1945Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P). (258 aa)
SCO1946SCC54.06c, pgk, phosphoglycerate kinase, len: 403 aa; member of a family of proteins highly conserved across prokaryotes and eukaryotes, e.g. SW:PGK_BACSU Pgk, phosphoglycerate kinase from Bacillus subtilis (394 aa) fasta scores; opt: 1263, z-score: 1322.3, E(): 0, (51.2% identity in 404 aa overlap) and SW:PGKH_SPIOL phosphoglycerate kinase from Spinacia oleracea (Spinach) (433 aa) fasta scores; opt: 1200, z-score: 1256.1, E(): 0, (49.9% identity in 407 aa overlap). Contains PS00111 Phosphoglycerate kinase signature and Pfam match to entry PF00162 PGK, Phosphoglycerate kinases, score 6 [...] (403 aa)
SCO1947Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the glyceraldehyde-3-phosphate dehydrogenase [...] (336 aa)
SCO1957SCC54.17, probable fructokinase, len: 302 aa; similar to many e.g. SW:SCRK_RHILT Frk, fructokinase from Rhizobium leguminosarum biovar trifolii (326 aa) fasta scores; opt: 617, z-score: 682.4, E(): 1.1e-30, (41.0% identity in 288 aa overlap). Contains PS00584 pfkB family of carbohydrate kinases signature 2 and Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase, score 132.90, E-value 9.6e-41. (302 aa)
SCO2014SC7H2.28c, pyk1, pyruvate kinase, len: 478 aa; strongly similar to many e.g. SW:KPYK_CORGL pyruvate kinase from Corynebacterium glutamicum (475 aa) fasta scores; opt: 1800, z-score: 2008.1, E(): 0, (59.6% identity in 473 aa overlap). Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. (478 aa)
SCO21196-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (342 aa)
SCO2145Putative glycerate kinase; SC6G10.18, unknown, len: 432aa; similar to many hypothetical proteins eg. SW:YXAA_BACSU hypothetical protein from Bacillus subtilis (382 aa) fasta scores; opt: 1005, z-score: 1049.9, E(): 0, (44.1% identity in 381 aa overlap). Note predicted C-terminal overlap with downstream CDS. Simialr also to SW:GRK_BACSU (EMBL:AB005554) Bacillus subtilis glycerate kinase (EC 2.7.1.31) GlxK or S14A, 382 aa; fasta scores: opt: 1005 Z-score:1015.2 E(): 6.5e-49; 44.094% identity in 381 aa overlap. (432 aa)
SCO2298SCC30.06, kdgA, KHG/KDPG aldolase, len: 219 aa; highly similar to SW:ALKH_ECOLI (EMBL:X68871) Escherichia coli KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) (phospho-2-dehydro-3-deoxygluconate aldolase) (phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)] KdgA, 213 aa; fasta scores: opt: 757 z-score: 811.9 E(): 0; 55.0% identity in 202 aa overlap. Contains Pfam match to entry PF01081 Aldolase, KD [...] (219 aa)
SCO2401SC4A7.29, possible dehydratase, len: 388 aa; similar to C-terminal region of SW:DGOA_ECOLI (EMBL:L10328) Escherichia coli galactonate dehydratase (EC 4.2.1.6) GdoA, 587 aa; fasta scores: opt: 751 z-score: 864.7 E(): 0; 35.0% identity in 383 aa overlap. Contains Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme family. (388 aa)
SCO2462SC7A8.01, probable sugar kinase (fragment), len: >434 aa; similar to TR:CAB61582 (EMBL:AL133210) Streptomyces coelicolor xylulose kinase (fragment) XylB, 432 aa; fasta scores: opt: 822 z-score: 871.9 E(): 0; 38.8% identity in 418 aa overlap and to SW:XYLB_STRRU (EMBL:M73789) Streptomyces rubiginosus xylulose kinase (EC 2.7.1.17) XylB, 481 aa; fasta scores: opt: 814 z-score: 862.8 E(): 0; 39.5% identity in 423 aa overlap. Contains Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases and PS00445 FGGY family of carbohydrate kinases signature 2; SCC24.33, probable sugar ki [...] (482 aa)
SCO2627SC8E4.02c, probable sugar-phosphate isomerase, len: 159 aa; similar to TR:O53192 (EMBL:AL021246) Mycobacterium tuberculosis putative isomerase MTV008.21c, 162 aa; fasta scores: opt: 665 z-score: 811.6 E(): 0; 62.1% identity in 153 aa overlap and to SW:RPIB_ECOLI (EMBL:X82203) Escherichia coli ribose 5-phosphate isomerase B (EC 5.3.1.6) (phosphoriboisomerase B) RpiB, 149 aa; fasta scores: opt: 294 z-score: 366.6 E(): 5.2e-13; 37.5% identity in 144 aa overlap. (159 aa)
SCO2789Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa)
SCO2905Hypothetical protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine (GlcNAc) transport. (77 aa)
SCO2906SCE19A.06, possible PTS transmembrane component, len: 431 aa; similar to many PTS (phosphoenolpyruvate-dependent sugar phosphotransferase system) transmembrane and sugar-binding components e.g. TR:Q57071 (EMBL:X93360), GlcA, PtsG, Staphylococcus carnosus PTS system, glucose-specific IIABC component (675 aa), fasta scores; opt: 1120 z-score: 1260.6 E(): 0, 43.4% identity in 431 aa overlap. Similar to the adjacent CDS SCE19A.07, possible PTS transmembrane component (416 aa) (4.1% identity in 429 aa overlap).The homologous PTS family proteins have a C-terminal extension not present in thi [...] (431 aa)
SCO2907Putative PTS transmembrane component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine (GlcNAc) transport. High-affinity permease, which exhibits a narrow specificity for GlcNAc. Essential for C-signaling between vegetative growth and development. (416 aa)
SCO3096Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
SCO3122Putative nucleotidyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (482 aa)
SCO3123Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (324 aa)
SCO3196SCE22.13c, probable fructose-specific permease, len: 699 aa; similar to SW:PTFB_ECOLI (EMBL:M23196) Escherichia coli PTS system, fructose-specific IIBC component (EIIBC-fru) FruA 563 aa; fasta scores: opt: 1006 z-score: 1038.9 E(): 0; 43.7% identity in 583 aa overlap. Contains match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible hydrophobic membrane spanning regions in C-terminal domain. (699 aa)
SCO3197SCE22.14c, probable 1-phosphofructokinase, len: 315 aa; similar to SW:K1PF_RHOCA (EMBL:X53150) Rhodobacter capsulatus 1-phosphofructokinase (EC 2.7.1.56) (fructose 1-phosphate kinase) FruK, 316 aa; fasta scores: opt: 555 z-score: 576.5 E(): 1.2e-24; 37.8% identity in 315 aa overlap. Contains Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase and match to Prosite entry PS00583 pfkB family of carbohydrate kinases signature 1. (315 aa)
SCO3198SCE22.15c, probable deoR-family transcriptional regulator, len: 253 aa; similar to TR:Q9X9X5 (EMBL:AL096743) Streptomyces coelicolor putative transcriptional regulator SCI7.15, 258 aa; fasta scores: opt: 609 z-score: 704.8 E(): 8.5e-32; 43.1% identity in 248 aa overlap and to SW:GATR_ECOLI (EMBL:AE000298) Escherichia coli galactitol utilization operon repressor GatR, 259 aa; fasta scores: opt: 438 z-score: 509.7 E(): 6.3e-21; 33.6% identity in 256 aa overlap. Contains Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family. (253 aa)
SCO3473SCE65.09c, probable aldolase, len: 215 aa; similar to SW:ALKH_BACSU (EMBL:L47838) Bacillus subtilis KHG/KDPG aldolase AlkH, 347 aa; fasta scores: opt: 457 z-score: 523.2 E(): 9.1e-22; 39.5% identity in 200 aa overlap and to Streptomyces coelicolor SCE65.31c, 225 aa; fasta scores: opt: 424 z-score: 429.4 E(): 1.5e-18; 37.7% identity in 215 aa overlap. Contains Pfam match to entry PF01081 Aldolase, KDPG and KHG aldolase and match to Prosite entry PS00160 KDPG and KHG aldolases Schiff-base forming residue. (215 aa)
SCO3474SCE65.10c, possible sugar kinase, len: 333 aa; similar to SW:KDGK_BACSU (EMBL:L47838) Bacillus subtilis 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) KdgK, 324 aa; fasta scores: opt: 500 z-score: 585.4 E(): 3.1e-25; 34.1% identity in 299 aa overlap. Contains Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase. (333 aa)
SCO3475SCE65.11c, possible isomerase, len: 377 aa; similar to SW:ATB_RHOOP (EMBL:X99622) Rhodococcus opacus muconate cycloisomerase I (EC 5.5.1.1) CatB, 373 aa; fasta scores: opt: 390 z-score: 443.3 E(): 2.6e-17; 31.1% identity in 357 aa overlap. Contains Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme family PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. (377 aa)
SCO3476Putative short-chain dehydrogenase; SCE65.12c, probable dehydrogenase, len: 251 aa; similar to SW:KDUD_BACSU (EMBL:L47838) Bacillus subtilis 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125) KduD, 254 aa; fasta scores: opt: 833 z-score: 937.8 E(): 0; 52.0% identity in 248 aa overlap and to Streptomyces coelicolor SCI30A.02, 253 aa; fasta scores: opt: 605 z-score: 622.2 E(): 2.7e-29; 44.1% identity in 245 aa overlap. Contains Pfam matches to entry PF00106 adh_short, short chain dehydrogenase and to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus and match to [...] (251 aa)
SCO3478SCE65.14c, probable dehydrogenase, len: 344 aa; similar to TR:O50095 (EMBL:AP000006) Pyrococcus horikoshii 307aa long hypothetical phosphoglycerate dehydrogenase PH1387, 307 aa; fasta scores: opt: 687 z-score: 777.1 E(): 0; 40.5% identity in 291 aa overlap and to SW:SERA_METTH (EMBL:AE000870;) Methanobacterium thermoautotrophicum D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) SerA, 525 aa; fasta scores: opt: 664 z-score: 748.1 E(): 0; 39.0% identity in 282 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases and match to Prosite [...] (344 aa)
SCO3494SCE65.30c, probable sugar kinase, len: 326 aa; similar to TR:Q9ZFM1 (EMBL:AF098273) Bacillus stearothermophilus 2-keto-3-deoxy-gluconate kinase KdgK, 314 aa; fasta scores: opt: 598 z-score: 671.6 E(): 4.9e-30; 37.0% identity in 308 aa overlap and to SW:KDGK_BACSU (EMBL:L47838) Bacillus subtilis 2-dehydro-3-deoxygluconokinase (EC 2.7.1.4) KdgK, 324 aa; fasta scores: opt: 560 z-score: 629.2 E(): 1.1e-27; 35.4% identity in 311 aa overlap. Contains match to Pfam entry PF00294 pfkB, pfkB family carbohydrate kinase and match to Prosite entry PS00584 pfkB family of carbohydrate kinases signature 2. (326 aa)
SCO3495SCE65.31c probable aldolase, len: 225 aa; similar to TR:AAD35160 (EMBL:AE001693) Thermotoga maritima 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase TM0066, 205 aa; fasta scores: opt: 437 z-score: 460.7 E(): 2.8e-18; 39.1% identity in 174 aa overlap and to SW:ALKH_BACSU (EMBL:L47838) Bacillus subtilis Khg/KdpG aldolase KdgA, 196 aa; fasta scores: opt: 379 z-score: 401.8 E(): 5.3e-15; 37.9% identity in 177 aa overlap. Contains match to Pfam entry PF01081 Aldolase, KDPG and KHG aldolase. (225 aa)
SCO3649Putative fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
SCO3877SCH18.14c, probable 6-phosphogluconate dehydrogenase, len: 291 aa; identical to previously sequenced TR:Q53917 (EMBL:L27063) Streptomyces coelicolor 6-phosphogluconate dehydrogenase, 291 aa and highly similar to TR:O88014 (EMBL:AL031107) S. coelicolor SC5A7.08c probable 6-phosphogluconate dehydrogenase, 293 aa; fasta scores: opt: 1654 z-score: 1688.1 E(): 0; 83.4% identity in 289 aa overlap. Contains Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogenasesand match to Prosite entry. (291 aa)
SCO4209Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
SCO4283SCD95A.16c, probable sugar kinase, len: 310 aa; similar to SW:LACC_LACLA (EMBL:M60447) Lactococcus lactis tagatose-6-phosphate kinase (EC 2.7.1.144) (phosphotagatokinase) LacC, 310 aa; fasta scores: opt: 559 z-score: 579.1 E(): 8.5e-25; 35.9% identity in 304 aa overlap. Contains Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase and match to Prosite entry PS00583 pfkB family of carbohydrate kinases signature 1 and PS00584 pfkB family of carbohydrate kinases signature 2. (310 aa)
SCO4284SCD95A.17c, probable N-acetylglucosamine-6-phosphate deacetylase, len: 381 aa; similar to SW:NAGA_BACSU (EMBL:AF017113) Bacillus subtilis N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) NagA, 396 aa; fasta scores: opt: 656 z-score: 741.7 E(): 0; 34.5% identity in 386 aa overlap. (381 aa)
SCO4285SCD95A.18, possible sugar kinase, len: 326 aa; similar to TR:CAB60179 (EMBL:AL132824) Streptomyces coelicolor putative sugar kinase SCAH10.25, 382 aa; fasta scores: opt: 449 z-score: 453.3 E(): 8.7e-18; 37.2% identity in 301 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and 5x degenerate repeat: (S/A)AP. (326 aa)
SCO4736Putative phospho-sugar mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
SCO4740Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (615 aa)
SCO4920SCK13.12, probable deoR-family transcriptional regulator, len: 317 aa; similar to SW:GATR_ECOLI (EMBL:AE000298) Escherichia coli galactitol utilization operon repressor GatR, 259 aa; fasta scores: opt: 442 z-score: 423.7 E(): 4.6e-16; 34.6% identity in 237 aa overlap. Contains Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family and match to Prosite entry PS00894 Bacterial regulatory proteins, deoR family signature. Also contains possible helix-turn-helix motif at residues 8..29 (+4.06 SD). (317 aa)
SCO49882SCK36.11, probable carbohydrate kinase, len: 351 aa; similar to TR:Q9K6K5 (EMBL:AP001519) Bacillus halodurans 2-keto-3-deoxygluconate kinase (EC 2.7.1.45) KdgK or BH3724, 317 aa; fasta scores: opt: 578 Z-score: 638.8 bits: 126.5 E(): 5.7e-28; 38.835% identity in 309 aa overlap. Contains Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase. (351 aa)
SCO5047SCK7.20c, conserved hypothetical protein, len: 343 aa; similar to SW:GLPX_ECOLI (EMBL:Z11767) Escherichia coli hypothetical protein GlpX, 336 aa; fasta scores: opt: 789 z-score: 868.1 E(): 0; 46.5% identity in 325 aa overlap. (343 aa)
SCO5059SCBAC20F6.02, ppgK, polyphosphate glucokinase, len: 246 aa; highly similar to SW:PPGK_MYCTU (EMBL:U44834) Mycobacterium tuberculosis polyphosphate glucokinase (EC 2.7.1.63) PpgK or RV2702 or MTCY05A6.23, 265 aa; fasta scores: opt: 912 Z-score: 1042.8 bits: 200.5 E(): 1.7e-50; 57.322% identity in 239 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family. (246 aa)
SCO5236Putative glucosamine phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (261 aa)
SCO5423SC8F4.27c, pyk2, pyruvate kinase, len: 476 aa; strongly similar to many e.g. SW:Q46078 (KPYK_CORGL) pyruvate kinase from Corynebacterium glutamicum (Brevibacterium flavum) (475 aa) fasta scores; opt: 1693, z-score: 1907.7, E(): 0, 55.3% identity in 474 aa overlap and TRNEW:CAB52070 (EMBL:AL109732) pyruvate kinase from Streptomyces coelicolor (478 aa) fasta scores; opt: 2185, z-score: 2461.2, E(): 0, 69.3% identity in 473 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. (476 aa)
SCO54266-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (341 aa)
SCO5515SC8D9.27, serA, D-3-phosphoglycerate dehydrogenase, len: 529 aa; member of a family including egs. SW:SERA_MYCLE putative SerA, D-3-phosphoglycerate dehydrogenase from Mycobacterium leprae (528 aa) fasta scores; opt: 1889, z-score: 2032.0, E(): 0, (56.9% identity in 524 aa overlap) and SW:SERA_BACSU SerA, D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 1176, z-score: 1266.5, E(): 0, (39.7% identity in 529 aa overlap). Contains PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature, PS00670 D-isomer specific 2-hydroxyacid dehyd [...] (529 aa)
SCO5841Phosphocarrier protein hpr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. (93 aa)
SCO5852SC9B10.19, agaY, possible tagatose-bisphosphate aldolase, len: 282 aa; similar to eg. AGAY_ECOLI P42908 tagatose-bisphosphate aldolase agaY (286 aa), fasta scores; opt: 585 z-score: 725.0 E(): 3.2e-33, 37.6% identity in 279 aa overlap. (282 aa)
SCO6110SCBAC1A6.34c, probable sugar kinase, len: 308 aa; similar to SW:GLK_STRCO (EMBL:X65932) Streptomyces coelicolor glucokinase (EC 2.7.1.2) Glk or SC6E10.20c, 317 aa; fasta scores: opt: 391 z-score: 407.0 E(): 4.3e-15; 34.4% identity in 314 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and match to Prosite entry PS01125 ROK family signature. (308 aa)
SCO6260SCAH10.25, possible sugar kinase, len: 382 aa; similar to SW:GLK_STRCO (EMBL:X65932) Streptomyces coelicolor glucokinase (EC 2.7.1.2) (glucose kinase) Glk, 317 aa; fasta scores: opt: 1022 z-score: 1142.9 E(): 0; 46.6% identity in 311 aa overlap and to TR:CAB51974 EMBL:SC6E10 Streptomyces coelicolor SC6E10.20c, 317 aa; fasta scores: opt: 1022 z-score: 1035.4 E(): 0; 46.6% identity in 311 aa overlap. Contains a match to Pfam entry PF00480 ROK, ROK family and Prosite entry PS01125 ROK family signature. (382 aa)
SCO6466Putative transferase; SC9C7.02, conserved hypothetical protein, len: 380 aa; similar to many e.g. SW:YXAA_BACSU hypothetical protein from Bacillus subtilis (382 aa) fasta scores; opt: 1045, z-score: 998.9, E(): 0, (46.3% identity in 374 aa overlap) and to SW:GRK_BACSU (EMBL:AB005554) Bacillus subtilis glycerate kinase (EC 2.7.1.31) GlxK, 382 aa; fasta scores: opt: 1045 Z-score: 991.1 E(): 1.4e-47; 46.257% identity in 374 aa overlap. (380 aa)
SCO6497SC1E6.06, tktA2, probable transketolase, len: 615 aa; highly similar to eukaryotic transketolases e.g. TKT_HUMAN transketolase (EC 2.2.1.1) (623 aa), fasta scores; opt: 1909 z-score: 2169.3 E(): 0, 50.0% identity in 614 aa overlap; less similar to prokaryotic transketolases e.g. TKT_RHOSH transketolase (657 aa), fasta scores; opt: 477 z-score: 830.4 E(): 0, 31.3% identity in 635 aa overlap. Contains PS00802 Transketolase signature 2 and Pfam match to entry PF00456 transketolase, Transketolase, score 397.70, E-value 1.1e-115. Also similar to S. coelicolor tkt (SC5A7.13c) E(): 4.2e-20, 2 [...] (615 aa)
SCO6658SC5A7.08c, probable 6-phosphogluconate dehydrogenase, len: 293 aa; similar to many eukaryotic e.g. 6PGD_BACSU 6-phosphogluconate dehydrogenase, decarboxylating (468 aa), fasta sores; opt: 445 z-score: 616.2 E(): 4.4e-27, 36.6% identity in 287 aa overlap.also highly similar to S. coelicolor 6-phosphogluconate dehydrogenase (EMBL:L27063) TR:Q53917 (291 aa), fasta sores; opt: 1654 z-score: 2054.7 E(): 0, 83.4% identity in 289 aa overlap. Contains PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature and Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogen [...] (293 aa)
SCO6659SC5A7.09c, pgi, glucose-6-phosphate isomerase, len: 550 aa; highly similar to many e.g. G6PI_ECOLI glucose-6-phosphate isomerase (EC 5.3.1.9) (549 aa), fasta sores; opt: 1878 z-score: 1900.7 E(): 0, 53.6% identity in 545 aa overlap. Contains PS00174 Phosphoglucose isomerase signature 2 and Pfam match to entry PF00342 PGI, Phosphoglucose isomerase, score 897.30, E-value 4.4e-266. (550 aa)
SCO6661Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (592 aa)
SCO6662Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (381 aa)
SCO6663SC5A7.13c, tktB, probable transketolase, len: 698 aa; highly similar to many e.g. TKT2_ECOLI transketolase 2 (EC 2.2.1.1) (667 aa), fasta scores; opt: 1191 z-score: 1912.7 E(): 0, 46.0% identity in 683 aa overlap. Contains PS00802 Transketolase signature 2 and Pfam match to entry PF00456 transketolase, Transketolase, score 1163.10, E-value 0; Belongs to the transketolase family. (698 aa)
SCO6818Putative phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
SCO7040SC4G1.06c, gap2, glyceraldehyde-3-phosphate dehydrogenase, len: 481 aa; highly similar to TR:O68923 (EMBL:AF058302) Streptomyces roseofulvus glyceraldehyde-3-phosphate dehydrogenase homolog GapX, 461 aa; fasta scores: opt: 2562 z-score: 2921.8 E(): 0; 84.5% identity in 459 aa overlap and to many eukaryotic homologos, e.g. SW:G3PA_MAIZE (EMBL:X15408) Zea mays glyceraldehyde-3-phosphate dehydrogenase A, chloroplast precursor (EC 1.2.1.12) GapA, 403 aa; fasta scores: opt: 793 z-score: 907.5 E(): 0; 39.6% identity in 366 aa overlap. Contains Pfam match to entry PF00044 gpdh, glyceraldehyde [...] (481 aa)
SCO7443Phosphoglucomutase; SC6D11.39, pgm, phosphoglucomutase (EC 5.4.2.2), len: 546 aa. Highly similar to many phosphoglucomutases e.g. Escherichia coli SW:PGMU_ECOLI(EMBL:U08369) phosphoglucomutase (EC 5.4.2.2) (546 aa), fasta scores opt: 2216 z-score: 2396.0 E():0 60.8% identity in 538 aa overlap. Contains a Prosite hit to PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature and a Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase. (546 aa)
SCO7511SCBAC25F8.03, gap2, glyceraldehyde 3-phosphate dehydrogenase, len: 332 aa; highly similar to SW:G3P_STRAU (EMBL:U21191) Streptomyces aureofaciens glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12) Gap, 332 aa; fasta scores: opt: 1898 Z-score: 2070.6 bits: 391.5 E(): 1e-107; 88.855% identity in 332 aa overlap and to TR:CAB38137 (EMBL:AL035591) Streptomyces coelicolor glyceraldehyde 3-phosphate dehydrogenase Gap or SCC54.07c, 337 aa; fasta scores: opt: 1272 Z-score: 1174.4 bits: 225.7 E(): 1.1e-59; 57.831% identity in 332 aa overlap. Contains Pfam matches to entries PF00044 gpdh, Gly [...] (332 aa)
SCO7568SC5F1.22c, possible regulatory protein, len: 319 aa; similar to TR:O50502 (EMBL:AL009199) Streptomyces coelicolor probable transcriptional repressor protein SC7B7.05, 403 aa; fasta scores: opt: 377 z-score: 404.3 E(): 5.5e-15; 29.3% identity in 290 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family. (319 aa)
SCO7629SC10F4.02, spaA, probable starvation sensing protein, len: 413 aa; identical to previously sequenced TR:P95726 (EMBL:X94190) Streptomyces coelicolor spaA gene, 413 aa. Contains Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme family and match to Prosite entry PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. (413 aa)
SCO7638Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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