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SCO5112 SCO5112 SCO5113 SCO5113 SCO5114 SCO5114 SCO5115 SCO5115 SCO5116 SCO5116 SCO5117 SCO5117 SCO5118 SCO5118 SCO5119 SCO5119 SCO5120 SCO5120 SCO5121 SCO5121 SCO5476 SCO5476 SCO5477 SCO5477 SCO5478 SCO5478 SCO5479 SCO5479 SCO5480 SCO5480 SCO5911 SCO5911 SCO7563 SCO7563 SCO7564 SCO7564 SCO7565 SCO7565 SCO7566 SCO7566 SCO7567 SCO7567 SCO7677 SCO7677 SCO7678 SCO7678 SCO7679 SCO7679 SCO7680 SCO7680
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO5112SCBAC31E11.08, bldKA, possible ABC transport system integral membrane protein, len: 343 aa; identical to previously sequenced TR:P72406 (EMBL:U68036) Streptomyces coelicolor BldKA, 335 aa. Methionine start codon 9 amino acids upstream from the previous sequence start; possible frameshift from frame 2 into frame 1 in the previously sequenced DNA. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possibl [...] (343 aa)
SCO5113SCBAC31E11.09, bldKB, possible ABC transport system lipoprotein, len: 600 aa; almost identical to TR:P72407 (EMBL:U68036) Streptomyces coelicolor BldKB, 602 aa. Contains 4x Pfam matches to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5, match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop) and correctly situated match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains possible N-terminal region signal peptide sequence. (600 aa)
SCO5114SCBAC31E11.10, bldKC, possible ABC transport system integral membrane protein, len: 325 aa; almost identical to previously sequenced TR:P72408 (EMBL:U68036) Streptomyces coelicolor BldKC, 323 aa. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Also contains possible hydrophobic membrane spanning regions. (325 aa)
SCO5115SCBAC31E11.11, bldKD, putative ABC transporter intracellular ATPase subunit, len: 353 aa; almost identical to previously sequenced TR:P72409 (EMBL:U680360) Streptomyces coelicolor BldKD putative ABC transporter intracellular ATPase subunit, 353 aa and similar to TR:O86574 (EMBL:AL031184) Streptomyces coelicolor SC2A11.13, 366 aa; fasta scores: opt: 1427 Z-score: 1344.1 bits: 257.3 E(): 3.8e-69; 60.340% identity in 353 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter and match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transp [...] (353 aa)
SCO5116SC9E12.01, probable peptide transport system ATP-binding protein (fragment), len: >142 aa; similar to SW:OPPF_ECOLI (EMBL:AE000223) Escherichia coli oligopeptide transport protein ATP-binding protein OppF, 334 aa; fasta scores: opt: 344 z-score: 423.0 E(): 4.3e-16; 56.5% identity in 92 aa overlap and to TR:O86575 (EMBL:AL031184) Streptomyces coelicolor oligopeptide ABC transporter ATP-binding protein SC2A11.14, 496 aa; fasta scores: opt: 488 z-score: 576.6 E(): 1.7e-26; 56.6% identity in 136 aa overlap; SCBAC31E11.12, bldKE, putative ABC transporter intracellular ATPase subunit (fragme [...] (381 aa)
SCO5117SC9E12.02, possible peptide transport system secreted peptide-binding protein, len: 544 aa; similar to SW:OPPA_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide-binding protein OppA precursor, 545 aa; fasta scores: opt: 648 z-score: 642.6 E(): 2.5e-28; 26.1% identity in 552 aa overlap and to TR:P72407 (EMBL:U68036) Streptomyces coelicolor SpoOKA homologue BldKB, 602 aa; blastp scores: Score = 165 (58.1 bits), Expect = 2.9e-10, Sum P(2) = 2.9e-10; Identities = 116/502 (23%), Positives = 202/502 (40%). Contains 2x Pfam matches to entry PF00496 SBP_bac_5, Bacterial extracellular solute-b [...] (544 aa)
SCO5118SC9E12.03, probable peptide transport system integral membrane protein, len: 307 aa; similar to TR: SW:OPPB_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide transport system permease protein OppB, 311 aa; fasta scores: opt: 688 z-score: 788.7 E(): 0; 36.0% identity in 308 aa overlap and to TR:P72408 (EMBL:U68036) Streptomyces coelicolor SpoOKC homologue BldKC, 323 aa; blastp scores: Score = 354 (124.6 bits), Expect = 1.9e-32, P = 1.9e-32; Identities = 82/235 (34%), Positives = 138/235 (58%). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems [...] (307 aa)
SCO5119SC9E12.04, probable peptide transport system integral membrane protein, len: 305 aa; similar to SW:OPPC_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide transport system permease protein OppC, 305 aa; fasta scores: opt: 670 z-score: 745.0 E(): 0; 35.5% identity in 296 aa overlap and to TR:P72406 (EMBL:U68036) Streptomyces coelicolor SpoOKB homologue BldKA, 335 aa; blastp scores: Score = 382 (134.5 bits), Expect = 9.1e-41, Sum P(2) = 9.1e-41; Identities = 88/231 (38%), Positives = 134/231 (58%). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport syste [...] (305 aa)
SCO5120SC9E12.05, probable peptide transport system ATP-binding protein, len: 327 aa; similar to SW:OPPD_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide transport system ATP-binding protein OppD, 358 aa; fasta scores: opt: 1126 z-score: 1167.7 E(): 0; 53.9% identity in 310 aa overlap, to TR:P72409 (EMBL:U68036) Streptomyces coelicolor putative ABC transporter intracellular ATPase subunit BldKD, 353 aa; fasta scores: opt: 1035 z-score: 1074.2 E(): 0; 51.5% identity in 326 aa overlap and to TR:O86574 (EMBL:AL031184) Streptomyces coelicolor oligopeptide ABC transporter ATP-binding protein SC2 [...] (327 aa)
SCO5121SC9E12.06, probable peptide transport system ATP-binding protein, len: 356 aa; similar to SW:APPF_BACSU (EMBL:U20909) Bacillus subtilis oligopeptide transport ATP-binding protein AppF, 329 aa; fasta scores: opt: 1255 z-score: 1332.6 E(): 0; 57.3% identity in 335 aa overlap, to TR:P72410 (EMBL:U68036) Streptomyces coelicolor putative ABC transporter intracellular ATPase subunit BldKE (fragment), 284 aa; fasta scores: opt: 999 z-score: 1063.6 E(): 0; 58.1% identity in 260 aa overlap and to TR:O86575 (EMBL:AL031184) Streptomyces coelicolor oligopeptide ABC transporter ATP-binding protein [...] (356 aa)
SCO5476SC2A11.10, probable oligopeptide transport integral membrane protein, len: 335 aa; similar to mnay e.g. APPC_BACSU oligopeptide transport permease protein appC (303 aa), fasta scores; opt: 465 z-score: 1038.5 E(): 0, 41.4% identity in 309 aa overlap. Also similar to S. coelicolor TR:P72406 (EMBL:U68036) bldKA (335 aa), fasta scores; opt: 912 z-score: 1192.3 E(): 0, 42.1% identity in 330 aa overlap. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp signature and Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membr [...] (335 aa)
SCO5477SC2A11.11, probable oligopeptide-binding lipoprotein, len: 600 aa; similar to e.g. OPPA_BACSU oligopeptide-binding protein oppA precursor (545 aa), fasta scores; opt: 401 z-score: 242.5 E(): 3e-06, 25.5% identity in 554 aa overlap Also similar to S. coelicolor TR:P72407 (EMBL:U68036) bldKB (602 aa), fasta scores; opt: 702 z-score: 583.5 E(): 3e-25, 29.3% identity in 614 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site, and Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-bind [...] (600 aa)
SCO5478SC2A11.12, probable oligopeptide transport system integral membrane protein, len: 332 aa; similar to many e.g. OPPB_ECOLI oligopeptide transport system permease protein (306 aa), fasta scores; opt: 568 z-score: 807.4 E(): 0, 35.0% identity in 337 aa overlap Also similar to S. coelicolor TR:P72408 (EMBL:U68036) bldKC (323 aa), fasta scores; opt: 875 z-score: 1186.1 E(): 0 42.4% identity in 337 aa overlap. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp signature and Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner [...] (332 aa)
SCO5479SC2A11.13, probable oligopeptide ABC transporter ATP-binding protein, len: 365 aa; similar to many e.g. OPPD_BACSU oligopeptide transport ATP-binding protein (336 aa), fasta scores; opt: 1089 z-score: 1413.1 E(): 0, 52.3% identity in 323 aa overlap Also similar to S. coelicolor TR:P72409 (EMBL:U68036) bldKD (353 aa), fasta scores; opt: 1396 z-score: 1731.9 E(): 0, 58.4% identity in 365 aa overlap. Contains PS00017 ATP /GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature and Pfam match to entry PF00005 ABC_tran, ABC transporters, score 203.50, E-value 3.3e-57. (365 aa)
SCO5480SC2A11.14, probable oligopeptide ABC transporter ATP-binding protein, len: 496 aa; similar to many e.g. APPF_BACSU oligopeptide transport ATP-binding protein (329 aa), fasta scores; opt: 1284 z-score: 1056.3 E(): 0, 56.4% identity in 326 aa overlap Also similar to S. coelicolor TR:P72410 (EMBL:U68036) bldKE (284 aa), fasta scores; opt: 1114 z-score: 1091.6 E(): 0, 59.3% identity in 280 aa overlap. Contains PS00017 ATP /GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature and Pfam match to entry PF00005 ABC_tran, ABC transporters, score 202.90, E-value 4.8e-57. C [...] (496 aa)
SCO5911SC10A5.16c, possible oligopeptide binding protein, len: 521; weak similarity to many eg. OPPA_SALTY P06202 periplasmic oligopeptide-binding protein (542 aa), fasta scores; opt: 343 z-score: 306.2 E(): 7.4e-10, 25.0% i dentity in 537 aa overlap. Contains N-terminal signal seque nce. (521 aa)
SCO7563SC5F1.17, possible ABC transporter solute binding lipoprotein, len: 516 aa; similar to TR:Q9KFX3 (EMBL:AP001508) Bacillus halodurans oligopeptide ABC transporter AppA, 516 aa; fasta scores: opt: 708 z-score: 807.2 E(): 0; 29.7% identity in 482 aa overlap. Contains 2x Pfam matches to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 and correctly situated match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains possible N-terminal signal peptide sequence. (516 aa)
SCO7564SC5F1.18, possible oligopeptide ABC transporter integral membrane protein, len: 330 aa; similar to TR:Q9KFX2 (EMBL:AP001508) Bacillus halodurans oligopeptide ABC transporter (permease) AppB, 305 aa; fasta scores: opt: 883 z-score: 1023.7 E(): 0; 44.8% identity in 299 aa overlap and to SW:OPPB_ECOLI (EMBL:AE000223) Escherichia coli oligopeptide transport system permease protein OppB, 306 aa; fasta scores: opt: 680 z-score: 790.0 E(): 0; 36.0% identity in 308 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component [...] (330 aa)
SCO7565SC5F1.19, probable oligopeptide ABC transporter integral membrane protein, len: 301 aa; similar to SW:DPPC_ECOLI (EMBL:L08399) Escherichia coli dipeptide transport system permease protein DppC, 300 aa; fasta scores: opt: 805 z-score: 912.6 E(): 0; 45.2% identity in 270 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. Also contains possible hydrophobic membrane spanning regions. (301 aa)
SCO7566SC5F1.20, probable oligopeptide ABC transporter ATP-binding protein, len: 288 aa; similar to SW:OPPD_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide transport ATP-binding protein OppD, 358 aa; fasta scores: opt: 934 z-score: 1022.9 E(): 0; 54.2% identity in 262 aa overlap and to TR:CAC05750 (EMBL:AL391751) Streptomyces coelicolor putative peptide transport system ATP-binding protein SC9E12.05, 327 aa; fasta scores: opt: 905 z-score: 714.2 E(): 4e-34; 53.5% identity in 260 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter and match to Prosite entry PS00017 AT [...] (288 aa)
SCO7567SC5F1.21, probable oligopeptide ABC transporter ATP-binding protein, len: 316 aa; similar to SW:OPPF_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide transport ATP-binding protein OppF, 308 aa; fasta scores: opt: 811 z-score: 836.7 E(): 0; 46.9% identity in 273 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter and matches to Prosite entries PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transporters family signature. (316 aa)
SCO7677SC4C2.12, possible secreted solute-binding protein, len: 528 aa; similar to TR:P96429 (EMBL:Z79692) Sinorhizobium meliloti periplasmic binding protein ORF23, 537 aa; fasta scores: opt: 644 z-score: 679.5 E(): 2.6e-30; 28.8% identity in 525 aa overlap. Contains Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 and correctly situated match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains possible N-terminal region signal peptide sequence. (528 aa)
SCO7678SC4C2.13, possible metal transport integral membrane protein, len: 316 aa; similar to SW:NIKB_ECOLI (EMBL:X73143) Escherichia coli nickel transport system permease protein NikB, 314 aa; fasta scores: opt: 490 z-score: 547.6 E(): 5.8e-23; 30.4% identity in 313 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Also contains possible hydrophobic membrane spanning regions and possible N-terminal signal peptide sequence. (316 aa)
SCO7679SC4C2.14, possible transport system integral membrane protein, len: 284 aa; similar to SW:Y4TQ_RHISN (EMBL:Z68203) Rhizobium sp. probable peptide ABC transporter permease protein Y4tQ, 291 aa; fasta scores: opt: 433 z-score: 466.4 E(): 1.9e-18; 33.2% identity in 277 aa overlap. Contains possible hydrophobic membrane spanning regions. (284 aa)
SCO7680SC4C2.15, possible ABC transporter ATP-binding protein, len: 541 aa; similar to TR:AAG05449 (EMBL:AE004632) Pseudomonas aeruginosa probable ATP-binding component of ABC transporter PA2061, 536 aa; fasta scores: opt: 861 z-score: 716.8 E(): 2.2e-32; 37.4% identity in 522 aa overlap. Contains 2x Pfam matches to entry PF00005 ABC_tran, ABC transporter and 2x matches to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop) and 2x to PS00211 ABC transporters family signature. (541 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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