STRINGSTRING
SCO3452 SCO3452 SCO3453 SCO3453 SCO3454 SCO3454 SCO3455 SCO3455 SCO3456 SCO3456 SCO3457 SCO3457 SCO5658 SCO5658 SCO5667 SCO5667 SCO5668 SCO5668 SCO5669 SCO5669 SCO5670 SCO5670 SCO5671 SCO5671 SCO5672 SCO5672 SCO5923 SCO5923 SCO5924 SCO5924 SCO5925 SCO5925 SCO5927 SCO5927 SCO5928 SCO5928
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO3452SCE46.09c, probable methyltransferase, len: 359 aa; similar to TR:AAF00618 (EMBL:AF166383) Mus musculus methyltransferase, 336 aa; fasta scores: opt: 868 z-score: 1022.0 E(): 0; 44.7% identity in 320 aa overlap and to SW:GRC2_LACLA (EMBL:L14679) Lactococcus lactis probable menaquinone biosynthesis methyltransferase (EC 2.1.1.-), 252 aa; fasta scores: opt: 221 z-score: 265.2 E(): 2e-07; 38.7% identity in 111 aa overlap. Contains Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5 methyltransferase family. (359 aa)
SCO3453SCE46.10c, probable ABC-transporter ATP binding protein, len: 354 aa; similar to TR:CAB49712 (EMBL:AJ248285) Pyrococcus abyssi ABC-transporter ATP binding protein, 329 aa; fasta scores opt: 708 z-score: 742.4 E(): 0; 43.9% identity in 280 aa overlap and to SW:CYSA_ECOLI (EMBL:M32101) Escherichia coli sulfate transport ATP-binding protein CysA, 365 aa; fasta scores: opt: 668 z-score: 700.3 E(): 1.2e-31; 38.6% identity in 332 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter and two matches to Prosite entries PS00211 ABC transporters family signature and PS00017 [...] (354 aa)
SCO3454SCE46.11c, possible ABC-transporter membrane protein, len: 280 aa; similar to TR:Q44381 (EMBL:U60011) Agrobacterium tumefaciens inner membrane protein MotD, 273 aa; fasta scores: opt: 360 z-score: 418.0 E(): 6.1e-16; 29.3% identity in 256 aa overlap and to SW:POTC_ECOLI (EMBL:M64519) Escherichia coli spermidine/putrescine transport system permease protein PotC, 264 aa; fasta scores: opt: 309 z-score: 360.4 E(): 1e-12; 25.8% identity in 260 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match [...] (280 aa)
SCO3455SCE46.12c, possible ABC-transporter transport protein, len: 285 aa; similar to TR:O57756 (EMBL:AP000001) Pyrococcus horikoshii 284 aa long hypothetical sugar transport membrane protein, 284 aa; fasta scores: opt: 281 z-score: 329.5 E(): 5.2e-11; 26.6% identity in 278 aa overlap and to SW:UGPA_ECOLI (EMBL:X13141) Escherichia coli SN-glycerol-3-phosphate transport system permease protein UgpA, 295 aa; fasta scores: opt: 233 z-score: 274.6 E(): 6e-08; 28.7% identity in 279 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membra [...] (285 aa)
SCO3456SCE46.13c, possible secreted protein, len: 135 aa; similar to TR:CAC41457 (EMBL:AL591782) Rhizobium meliloti conserved hypothetical protein SMC02589, 408 aa; fasta scores: opt: 927 Z-score: 1029.9 E(): 9.8e-50; 37.198% identity in 414 aa overlap. Contains possible N-terminal region signal peptide sequence. (417 aa)
SCO3457SCE46.14, possible transmembrane protein, len: 205 aa; similar to TR:P76226 (EMBL:AE000270) Escherichia coli from bases 1830199 to 1840304, 208 aa; fasta scores: opt: 402 z-score: 471.0 E(): 6.9e-19; 37.4% identity in 206 aa overlap and to TR:CAB50482 (EMBL:AJ248288) Pyrococcus abyssi predicted CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase PgsA, 185 aa; fasta scores: opt: 216 z-score: 259.1 E(): 4.4e-07; 31.2% identity in 205 aa overlap. (205 aa)
SCO5658SC6A9.09c, possible polyamine-binding lipoprotein, len: 399 aa; some similarity to several spermidine. (399 aa)
SCO5667SC8B7.11c, probable ABC-transporter polyamine-binding lipoprotein, len: 399 aa; similar to e.g. POTF_ECOLI putrescine-binding periplasmic protein precursor (370 aa), fasta scores; opt: 327 z-score: 259.5 E(): 3.4e-07, 28.5% identity in 365 aa overlap. Also similar to upstream gene SC6A9.09c (E(): 0, 46.8% identity in 391 aa overlap). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site and PS00017 ATP/GTP-binding site motif A (P-loop). Contains possible N-terminal region signal sequence peptide. (399 aa)
SCO5668Putative polyamine ABC-transporter ATP-binding p rotein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (397 aa)
SCO5669SC8B7.09c, probable polyamine ABC-transporter integr al membrane protein, len: 309 aa; similar to many e.g. POTB _ECOLI spermidine/putrescine transport system permease (275 aa), fasta scores; opt: 548 z-score: 685.1 E(): 6.6e-31, 3 6.9% identity in 274 aa overlap. Contains Pfam match to ent ry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, score 38.20, E-value 1.8e -07. (309 aa)
SCO5670SC8B7.08c, probable polyamine ABC-transporter integr al membrane protein, len: 266 aa; similar to many e.g. POTC _ECOLI spermidine/putrescine transport system permease (264 aa), fasta scores; opt: 579 z-score: 718.8 E(): 8.8e-33, 3 5.5% identity in 251 aa overlap. Contains Pfam match to ent ry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, score 23.00, E-value 0.00 7. (266 aa)
SCO5671SC8B7.07c, possible oxidoreductase, len: 475 aa; some similarity to e.g. ORDL_ECOLI probable oxidoreductase ord L (426 aa), fasta scores; opt: 413 z-score: 280.3 E(): 2.4 e-08, 32.1% identity in 436 aa overlap. (475 aa)
SCO5672Hypothetical protein; SC8B7.06c, unknown, len: 152 aa. (152 aa)
SCO5923SC10A5.28c, ABC-transporter ATP-binding protein, len : 361 aa; similar to many eg. Streptomyces reticuli TR:P964 83 (EMBL:Y08921) MSIK PROTEIN involved in in cellobiose and maltose transport(377 aa), opt: 809 z-score: 1069.1 E(): 0, 40.4% identity in 381 aa overlap. Contains PS00017 ATP/GT P-binding site motif A (P-loop). PS00211 ABC transporters f amily signature and Pfam match to entry ABC_tran PF00005, A BC transporters, score 35.90. (361 aa)
SCO5924SC10A5.29c, probable integral membrane protein, len: 589 aa; similar to many permeases eg. TR:Q44123 (EMBL:U050 42) iron utilisation protein AFUB from Actinobacillus pleur opneumoniae (687 aa), fasta scores; opt: 564 z-score: 426.3 E(): 1.5e-16, 25.0% identity in 547 aa overlap. (589 aa)
SCO5925Hypothetical protein; SC10A5.30c, unknown, len: 83 aa. (83 aa)
SCO5927Hypothetical protein; SC10A5.32c, unknown, len: 73. (73 aa)
SCO5928Hypothetical protein; SC10A5.33c, unknown, len: 234 aa. (234 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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