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SCO0436 | SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap. (56 aa) | ||||
SCO0569 | SC5G5.01c, possible 50S ribosomal protein L36 (fragment), len: >28 aa; similar to N-terminal region of SW:RL36_RICPR (EMBL:AJ235271) Rickettsia prowazekii 50S ribosomal protein L36 RpmJ or RP456, 41 aa; fasta scores: opt: 77 Z-score: 156.1 bits: 30.6 E(): 0.44; 48.276% identity in 29 aa overlap; St8B3.03c, possible ribosomal protein L36, len: 40aa: similar to many eg. TR:Q9A383 (EMBL:AE005994) from Caulobacter crescentus (41 aa) fasta scores; opt: 164, Z-score: 272.8, 60.976% identity (62.500% ungapped) in 41 aa overlap and SW:P28528 (RK36_GUITH) from Guillardia theta (Cryptomonas phi) [...] (40 aa) | ||||
SCO0570 | SC5G5.02c, rpmG2, 50S ribosomal protein L33, len: 54 aa; highly similar to SW:R331_STRCO (EMBL:AL049841) Streptomyces coelicolor 50S ribosomal protein L33 RpmG1 or SCE9.35c, 54 aa; fasta scores: opt: 294 Z-score: 436.0 bits: 83.8 E(): 1.1e-16; 81.481% identity in 54 aa overlap. Contains Pfam match to entry PF00471 Ribosomal_L33, Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa) | ||||
SCO0783 | 3SCF60.15, tetM, tetracycline resistance protein, len: 635 aa; identical to SW:TETM_STRLI (EMBL:M74049) Streptomyces lividans tetracycline resistance protein TetM, 639 aa. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family and PF00679 EFG_C, Elongation factor G C-terminus and match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop). (635 aa) | ||||
SCO1150 | SCG8A.04, rpmE2, 50S ribosomal protein L31, len: 90 aa; strongly similar to many eg. SW:O34967 (YTIA_BACSU) hypothetical ribosomal protein in dps-menE intergenic region from Bacillus subtilis (82 aa) fasta scores; opt: 297, z-score: 406.7, E(): 3.3e-15, 47.6% identity in 82 aa overlap and TR:Q9X8K6 (EMBL:AL049841) 50S ribosomal protein L31 from Streptomyces coelicolor (84 aa) fasta scores; opt: 399, z-score: 539.3, E(): 1.4e-22, 67.5% identity in 83 aa overlap. Contains Pfam match to entry PF01197 Ribosomal_L31, Ribosomal protein L31, Prosite match to PS00030 Eukaryotic putative RNA-bi [...] (90 aa) | ||||
SCO1321 | Elongation factor TU-3; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (392 aa) | ||||
SCO1505 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (204 aa) | ||||
SCO1598 | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). (127 aa) | ||||
SCO1599 | SCI35.21c, rpmI, 50S ribosomal protein L35, len: 64 aa; similar to many e.g. RL35_BACSU 50S ribosomal protein L35 (65 aa), fasta scores; opt: 179 z-score: 355.6 E(): 1.5e-12, 45.9% identity in 61 aa overlap; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) | ||||
SCO1600 | Putative translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (217 aa) | ||||
SCO2563 | 30s ribosomal protein S20; Binds directly to 16S ribosomal RNA. (88 aa) | ||||
SCO2596 | SCC88.07c, rpmA, 50S ribosomal protein L27, len: 84 aa; identical to SW:RL27_STRGR (EMBL:D87916) Streptomyces griseus 50S ribosomal protein L27 RpmA, 85 aa. Contains Pfam match to entry PF01016 Ribosomal_L27, Ribosomal L27 proteinand match to Prosite entry PS00831 Ribosomal protein L27 signature; Belongs to the bacterial ribosomal protein bL27 family. (84 aa) | ||||
SCO2597 | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (106 aa) | ||||
SCO2620 | Putative cell division trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (468 aa) | ||||
SCO2966 | Small protein B homologue; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] (159 aa) | ||||
SCO3124 | Ribosomal L25p family protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (198 aa) | ||||
SCO3425 | Putative 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa) | ||||
SCO3427 | SCE9.34c, rpmE, probable 50S ribosomal protein L31, len: 84 aa; similar to many e.g. SW:RK31_GUITH (EMBL:U81044) Guillardia theta chloroplast 50S ribosomal protein L31 (72 aa), fasta scores; opt: 149 z-score: 220.0 E(): 6.2e-05, 48.8% identity in 43 aa overlap. Contains Pfam match to entry PF01197 Ribosomal_L31, Ribosomal protein L31, score 59.20, E-value 8.7e-14 and PS01143 Ribosomal protein L31 signature. (84 aa) | ||||
SCO3428 | SCE9.35c, rpmG, probable 50S ribosomal protein L33, len: 54 aa; similar to many e.g. SW:RL33_ECOLI (EMBL:J01677), rpmG, Escherichia coli 50S ribosomal protein L33 (54 aa), fasta scores; opt: 162 z-score: 270.5 E(): 9.5e-08, 46.9% identity in 49 aa overlap. Contains Pfam match to entry PF00471 Ribosomal_L33, Ribosomal protein L33, score 37.80, E-value 2e-08; Belongs to the bacterial ribosomal protein bL33 family. (54 aa) | ||||
SCO3429 | SCE9.36, rpmB, probable 50S ribosomal protein L28, len: 73 aa; similar to many e.g. SW:RL28_ECOLI (EMBL:J01677), rpmB, Escherichia coli 50S ribosomal protein L28 (77 aa), fasta scores; opt: 235 z-score: 344.6 E(): 7.1e-12, 47.8% identity in 69 aa overlap. Contains Pfam match to entry PF00830 Ribosomal_L28, Ribosomal L28 family, score 88.70, E-value 1.2e-22; Belongs to the bacterial ribosomal protein bL28 family. (73 aa) | ||||
SCO3430 | Putative 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) | ||||
SCO3676 | SCH35.48c, possible integral membrane protein, len: 350aa; Contains possible membrane spanning hydrophobic regions in the C-terminal half and a hydrophobic N-terminal half. (350 aa) | ||||
SCO3906 | Putative 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa) | ||||
SCO3908 | Putative 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (78 aa) | ||||
SCO3909 | 50S ribosomal protein L9; Binds to the 23S rRNA. (148 aa) | ||||
SCO4635 | SCD82.06, rpmG3, 50S ribosomal protein L33, len: 54 aa; highly similar to SW:R331_BACSU (EMBL:D84432) Bacillus subtilis 50S ribosomal protein L33 type 1, RpmG1, 49 aa; fasta scores: opt: 235 z-score: 376.8 E(): 1.4e-13; 65.3% identity in 49 aa overlap. Contains Pfam match to entry PF00471 Ribosomal_L33, Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa) | ||||
SCO4647 | Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. (300 aa) | ||||
SCO4648 | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (144 aa) | ||||
SCO4649 | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (241 aa) | ||||
SCO4652 | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (176 aa) | ||||
SCO4653 | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (127 aa) | ||||
SCO4654 | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1161 aa) | ||||
SCO4659 | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS12 family. (123 aa) | ||||
SCO4660 | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) | ||||
SCO4661 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (708 aa) | ||||
SCO4662 | Elongation factor TU-1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa) | ||||
SCO4701 | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) | ||||
SCO4702 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (214 aa) | ||||
SCO4703 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (219 aa) | ||||
SCO4704 | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (139 aa) | ||||
SCO4705 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (278 aa) | ||||
SCO4706 | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa) | ||||
SCO4707 | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (125 aa) | ||||
SCO4708 | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (277 aa) | ||||
SCO4709 | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (139 aa) | ||||
SCO4710 | SCD31.35, rpmC, 50S ribosomal protein L29, len: 74 aa; highly similar to SW:RL29_BACST (PIR:A02825) Bacillus stearothermophilus 50S ribosomal protein L29 RpmC, 66 aa; fasta scores: opt: 244 z-score: 361.6 E(): 1e-12; 63.9% identity in 61 aa overlap. Contains Pfam match to entry PF00831 Ribosomal_L29, Ribosomal L29 protein and match to Prosite entry PS00323 Ribosomal protein S19 signature. (74 aa) | ||||
SCO4711 | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (95 aa) | ||||
SCO4712 | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) | ||||
SCO4713 | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (107 aa) | ||||
SCO4714 | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa) | ||||
SCO4715 | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) | ||||
SCO4716 | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) | ||||
SCO4717 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa) | ||||
SCO4718 | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (127 aa) | ||||
SCO4719 | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (201 aa) | ||||
SCO4720 | SCD31.45, rpmD, 50S ribosomal protein L30, len: 60 aa; identical to previously sequenced SW:RL30_STRCO (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein L30 RpmD, 60 aa. Contains Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e and match to Prosite entry PS00634 Ribosomal protein L30 signature. (60 aa) | ||||
SCO4721 | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa) | ||||
SCO4725 | Translational initiation factor IF1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa) | ||||
SCO4726 | SC6G4.04, rpmJ, 50S ribosomal protein L36, len: 37 aa; highly similar to many e.g. RL36_BACST 50S ribosomal protein L36 (37 aa), fasta scores; opt: 225 z-score: 380.1 E() : 6.6e-14, 78.4% identity in 37 aa overlap. Contains PS0082 8 Ribosomal protein L36 signature and Pfam match to entry PF00444 L36, Ribosomal protein L36, score 70.40, E-value 3.1 e-22; Belongs to the bacterial ribosomal protein bL36 family. (37 aa) | ||||
SCO4727 | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa) | ||||
SCO4728 | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (134 aa) | ||||
SCO4729 | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa) | ||||
SCO4730 | SC6G4.08, rplQ, 50S ribosomal protein L17, len: 168 aa; highly similar to many e.g. RL17_BACST 50S ribosomal protein L17 (119 aa), fasta scores; opt: 339 z-score: 597.2 E (): 5.3e-26, 47.4% identity in 116 aa overlap. Contains approx 50 aa C-terminal extension, not present in other RplQ. (168 aa) | ||||
SCO4734 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa) | ||||
SCO4735 | SC6G4.13, rpsI, 30S ribosomal protein S9, len: 170 a a; identical to RS9_STRCO 30S ribosomal protein S9 (170 aa) and highly similar to many e.g.RS9_ECOLI (129 aa), fasta s cores; opt: 408 z-score: 663.5 E(): 1.1e-29, 49.2% identity in 124 aa overlap. Contains PS00360 Ribosomal protein S9 s ignature and Pfam match to entry PF00380 S9, Ribosomal prot ein S9, score 162.60, E-value 1e-49; Belongs to the universal ribosomal protein uS9 family. (170 aa) | ||||
SCO5359 | 50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (74 aa) | ||||
SCO5564 | SC7A1.08c, rpmB, 50S ribosomal protein L28, len: 61aa; similar to many including SW:RL28_BACSU RpmB 50S ribosomal protein L28 from Bacillus subtilis (62 aa) fasta scores; opt: 171, z-score: 301.8, E(): 1.6e-09, (41.0% identity in 61 aa overlap). Contains Pfam match to entry PF00830 Ribosomal_L28, Ribosomal L28 family, score 74.50, E-value 2.2e-18; Belongs to the bacterial ribosomal protein bL28 family. (61 aa) | ||||
SCO5591 | SC2E1.08, rpsP, 30S ribosomal protein S16, highly similar to many e.g. RS16_MYCTU (162 aa), fatsa scores; opt:480 z-score: 771.3 E(): 0, 56.3% identity in 144 aa overlap. Contains PS00732 Ribosomal protein S16 signature; Belongs to the bacterial ribosomal protein bS16 family. (139 aa) | ||||
SCO5595 | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa) | ||||
SCO5624 | SC2E1.41, rpsB, 30S ribosomal protein S2, len: 310 aa; almost identical to RS2_STRCO 30S ribosomal protein S2 (242 aa), E(): 0, 96.7% identity in 242 aa overlap and also highly similar to many others e.g. RS2_ECOLI 30S ribosomal protein S2 (240 aa), fasta scores; opt: 744 z-score: 950.7 E(): 0, 50.4% identity in 224 aa overlap. Contains PS00962 Ribosomal protein S2 signature 1 and PS00211 ABC transporters family signature (probably a false positive). Also contains Pfam matches to entry S2 PF00318, Ribosomal protein S2, score 304.89 and to entry 60s_ribosomal PF00428, 60s Acidic ribosom [...] (310 aa) | ||||
SCO5625 | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity); Belongs to the EF-Ts family. (278 aa) | ||||
SCO5704 | Putative transcriptional termination/antitermination factor; Participates in both transcription termination and antitermination. (340 aa) | ||||
SCO5736 | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (95 aa) |