(5 nodes) Mixed, incl. Aldo/keto reductase, conserved site, and TauD/TfdA-like domain network (Streptomyces coelicolor)

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Your Input:
	SCO2938	SCE56.02, possible oxidoreductase, len: 336 aa; similar to TR:CAB61562 (EMBL:AL133171) Streptomyces coelicolor putative aldo/keto reductase (fragment) SCF81.28c, 307 aa; fasta scores: opt: 1370 z-score: 1572.6 E(): 0; 65.2% identity in 305 aa overlap and to SW:NORA_ASPFL (EMBL:U32377) Aspergillus flavus norsolorinic acid reductase (EC 1.1.1.-) NorA, 388 aa; fasta scores: opt: 572 z-score: 659.1 E(): 2.7e-29; 32.8% identity in 329 aa overlap. (336 aa)
	SCO4339	SCD12A.22c, possible reductase, len: 284 aa; similar to SW:STCV_EMENI (EMBL:U34740) Aspergillus nidulans putative sterigmatocystin biosynthesis dehydrogenase StcV, 387 aa; fasta scores: opt: 401 z-score: 462.6 E(): 2.6e-18; 32.0% identity in 284 aa overlap and to TR:O33936 (EMBL:U77454) Saccharopolyspora erythraea EryBII, 333 aa; fasta scores: opt: 970 z-score: 1111.9 E(): 0; 53.7% identity in 287 aa overlap. (284 aa)
	SCO4353	SCD19.08c, hypothetical protein, len: 52 aa; similar to N-terminal domain of TR:Q9S0N9 (EMBL:AB032523) Streptomyces avermitilis DTDP-4-keto-6-deoxy-L-hexose 2,3-reductase AveBVIII, 347 aa; fasta scores: opt: 165 z-score: 253.6 E(): 1.3e-06; 51.0% identity in 49 aa overlap and to N-terminal domain of Streptomyces coelicolor SCD19.07, 330 aa; fasta scores: opt: 293 z-score: 403.7 E(): 7.6e-17; 88.2% identity in 51 aa overlap. (52 aa)
	SCO7356	Oxidoreductase; SC9H11.10c, oxidoreductase, len: 276 aa. Highly similar to many including: Corynebacterium sp. SW:2DKG_CORSP(EMBL:M21193) 2,5-diketo-d-gluconic acid reductase (EC 1.1.1.-) (277 aa), fasta scores opt: 1006 z-score: 1188.8 E(): 0 52.9% identity in 274 aa overlap and Streptomyces coelicolor TR:Q9ZBW7(EMBL:AL034443;) putative oxidoreductase, SC4B5.01C (277 aa), fasta scores opt: 1018 z-score: 1202.9 E():0 56.3% identity in 268 aa overlap. Contains Prosite hits to PS00063 Aldo/keto reductase family putative active site signature, PS00062 Aldo/keto reductase family signature [...] (276 aa)
	SCO7357	SC9H11.11, probable dioxygenase, len: 328 aa. Highly similar to many including: Escherichia coli SW:TAUD_ECOLI(EMBL:D85613) alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.-.-) (282 aa), fasta scores opt: 462 z-score: 559.5 E(): 1.1e-23 35.0% identity in 294 aa overlap and Mycobacterium tuberculosis SW:YY06_MYCTU(EMBL:Z77165) putative dioxygenase RV3406 (EC 1.-.-.-) (295 aa), fasta scores opt: 523 z-score: 632.3 E(): 9.3e-28 41.6% identity in 308 aa overlap. (328 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO2938	SCO4353	gene:17760549	gene:17761998	SCE56.02, possible oxidoreductase, len: 336 aa; similar to TR:CAB61562 (EMBL:AL133171) Streptomyces coelicolor putative aldo/keto reductase (fragment) SCF81.28c, 307 aa; fasta scores: opt: 1370 z-score: 1572.6 E(): 0; 65.2% identity in 305 aa overlap and to SW:NORA_ASPFL (EMBL:U32377) Aspergillus flavus norsolorinic acid reductase (EC 1.1.1.-) NorA, 388 aa; fasta scores: opt: 572 z-score: 659.1 E(): 2.7e-29; 32.8% identity in 329 aa overlap.	SCD19.08c, hypothetical protein, len: 52 aa; similar to N-terminal domain of TR:Q9S0N9 (EMBL:AB032523) Streptomyces avermitilis DTDP-4-keto-6-deoxy-L-hexose 2,3-reductase AveBVIII, 347 aa; fasta scores: opt: 165 z-score: 253.6 E(): 1.3e-06; 51.0% identity in 49 aa overlap and to N-terminal domain of Streptomyces coelicolor SCD19.07, 330 aa; fasta scores: opt: 293 z-score: 403.7 E(): 7.6e-17; 88.2% identity in 51 aa overlap.	0.573
SCO4339	SCO4353	gene:17761984	gene:17761998	SCD12A.22c, possible reductase, len: 284 aa; similar to SW:STCV_EMENI (EMBL:U34740) Aspergillus nidulans putative sterigmatocystin biosynthesis dehydrogenase StcV, 387 aa; fasta scores: opt: 401 z-score: 462.6 E(): 2.6e-18; 32.0% identity in 284 aa overlap and to TR:O33936 (EMBL:U77454) Saccharopolyspora erythraea EryBII, 333 aa; fasta scores: opt: 970 z-score: 1111.9 E(): 0; 53.7% identity in 287 aa overlap.	SCD19.08c, hypothetical protein, len: 52 aa; similar to N-terminal domain of TR:Q9S0N9 (EMBL:AB032523) Streptomyces avermitilis DTDP-4-keto-6-deoxy-L-hexose 2,3-reductase AveBVIII, 347 aa; fasta scores: opt: 165 z-score: 253.6 E(): 1.3e-06; 51.0% identity in 49 aa overlap and to N-terminal domain of Streptomyces coelicolor SCD19.07, 330 aa; fasta scores: opt: 293 z-score: 403.7 E(): 7.6e-17; 88.2% identity in 51 aa overlap.	0.739
SCO4353	SCO2938	gene:17761998	gene:17760549	SCD19.08c, hypothetical protein, len: 52 aa; similar to N-terminal domain of TR:Q9S0N9 (EMBL:AB032523) Streptomyces avermitilis DTDP-4-keto-6-deoxy-L-hexose 2,3-reductase AveBVIII, 347 aa; fasta scores: opt: 165 z-score: 253.6 E(): 1.3e-06; 51.0% identity in 49 aa overlap and to N-terminal domain of Streptomyces coelicolor SCD19.07, 330 aa; fasta scores: opt: 293 z-score: 403.7 E(): 7.6e-17; 88.2% identity in 51 aa overlap.	SCE56.02, possible oxidoreductase, len: 336 aa; similar to TR:CAB61562 (EMBL:AL133171) Streptomyces coelicolor putative aldo/keto reductase (fragment) SCF81.28c, 307 aa; fasta scores: opt: 1370 z-score: 1572.6 E(): 0; 65.2% identity in 305 aa overlap and to SW:NORA_ASPFL (EMBL:U32377) Aspergillus flavus norsolorinic acid reductase (EC 1.1.1.-) NorA, 388 aa; fasta scores: opt: 572 z-score: 659.1 E(): 2.7e-29; 32.8% identity in 329 aa overlap.	0.573
SCO4353	SCO4339	gene:17761998	gene:17761984	SCD19.08c, hypothetical protein, len: 52 aa; similar to N-terminal domain of TR:Q9S0N9 (EMBL:AB032523) Streptomyces avermitilis DTDP-4-keto-6-deoxy-L-hexose 2,3-reductase AveBVIII, 347 aa; fasta scores: opt: 165 z-score: 253.6 E(): 1.3e-06; 51.0% identity in 49 aa overlap and to N-terminal domain of Streptomyces coelicolor SCD19.07, 330 aa; fasta scores: opt: 293 z-score: 403.7 E(): 7.6e-17; 88.2% identity in 51 aa overlap.	SCD12A.22c, possible reductase, len: 284 aa; similar to SW:STCV_EMENI (EMBL:U34740) Aspergillus nidulans putative sterigmatocystin biosynthesis dehydrogenase StcV, 387 aa; fasta scores: opt: 401 z-score: 462.6 E(): 2.6e-18; 32.0% identity in 284 aa overlap and to TR:O33936 (EMBL:U77454) Saccharopolyspora erythraea EryBII, 333 aa; fasta scores: opt: 970 z-score: 1111.9 E(): 0; 53.7% identity in 287 aa overlap.	0.739
SCO7356	SCO7357	gene:17765016	gene:17765017	Oxidoreductase; SC9H11.10c, oxidoreductase, len: 276 aa. Highly similar to many including: Corynebacterium sp. SW:2DKG_CORSP(EMBL:M21193) 2,5-diketo-d-gluconic acid reductase (EC 1.1.1.-) (277 aa), fasta scores opt: 1006 z-score: 1188.8 E(): 0 52.9% identity in 274 aa overlap and Streptomyces coelicolor TR:Q9ZBW7(EMBL:AL034443;) putative oxidoreductase, SC4B5.01C (277 aa), fasta scores opt: 1018 z-score: 1202.9 E():0 56.3% identity in 268 aa overlap. Contains Prosite hits to PS00063 Aldo/keto reductase family putative active site signature, PS00062 Aldo/keto reductase family signature [...]	SC9H11.11, probable dioxygenase, len: 328 aa. Highly similar to many including: Escherichia coli SW:TAUD_ECOLI(EMBL:D85613) alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.-.-) (282 aa), fasta scores opt: 462 z-score: 559.5 E(): 1.1e-23 35.0% identity in 294 aa overlap and Mycobacterium tuberculosis SW:YY06_MYCTU(EMBL:Z77165) putative dioxygenase RV3406 (EC 1.-.-.-) (295 aa), fasta scores opt: 523 z-score: 632.3 E(): 9.3e-28 41.6% identity in 308 aa overlap.	0.628
SCO7357	SCO7356	gene:17765017	gene:17765016	SC9H11.11, probable dioxygenase, len: 328 aa. Highly similar to many including: Escherichia coli SW:TAUD_ECOLI(EMBL:D85613) alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.-.-) (282 aa), fasta scores opt: 462 z-score: 559.5 E(): 1.1e-23 35.0% identity in 294 aa overlap and Mycobacterium tuberculosis SW:YY06_MYCTU(EMBL:Z77165) putative dioxygenase RV3406 (EC 1.-.-.-) (295 aa), fasta scores opt: 523 z-score: 632.3 E(): 9.3e-28 41.6% identity in 308 aa overlap.	Oxidoreductase; SC9H11.10c, oxidoreductase, len: 276 aa. Highly similar to many including: Corynebacterium sp. SW:2DKG_CORSP(EMBL:M21193) 2,5-diketo-d-gluconic acid reductase (EC 1.1.1.-) (277 aa), fasta scores opt: 1006 z-score: 1188.8 E(): 0 52.9% identity in 274 aa overlap and Streptomyces coelicolor TR:Q9ZBW7(EMBL:AL034443;) putative oxidoreductase, SC4B5.01C (277 aa), fasta scores opt: 1018 z-score: 1202.9 E():0 56.3% identity in 268 aa overlap. Contains Prosite hits to PS00063 Aldo/keto reductase family putative active site signature, PS00062 Aldo/keto reductase family signature [...]	0.628