STRINGSTRING
SCO0437 SCO0437 SCO0438 SCO0438 SCO0439 SCO0439 SCO0440 SCO0440 SCO0441 SCO0441 SCO0442 SCO0442 SCO0443 SCO0443 SCO1407 SCO1407 SCO1408 SCO1408 SCO1409 SCO1409 SCO1410 SCO1410 SCO1411 SCO1411 SCO1412 SCO1412
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO0437SCF51A.15c, hypothetical protein, len: 341 aa; similar to TR:Q9A8Z7 (EMBL:AE005797) Caulobacter crescentus hypothetical protein CC1198, 331 aa; fasta scores: opt: 855 Z-score: 977.0 E(): 8.7e-47; 45.181% identity in 332 aa overlap. (341 aa)
SCO0438Pyrrolidone-carboxylate peptidase (EC 3.4.19.3); Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family. (216 aa)
SCO0439SCF51A.17c, possible membrane protein, len: 324 aa. Contains a possible N-terminal signal sequence and multiple possible membrane spanning hydrophobic domains. (324 aa)
SCO0440SCF51A.18c, possible integral membrane protein, len: 239 aa. Contains multiple possible membrane spanning hydrophobic domains. (239 aa)
SCO0441Conserved hypothetical protein SCF51A.19; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (250 aa)
SCO0442Conserved hypothetical protein; SCF51A.20, unknown, len: 252 aa. Similar to a number of hypothetical proteins e.g. Escherichia coli SW:YBGJ_ECOLI (EMBL; AE000174) hypothetical 23.9 KD protein in phrB-nei intergenic region (218 aa), fasta scores: opt: 477 z-score: 492.1 E(): 4.7e-20 43.5% identity in 214 aa overlap. (252 aa)
SCO0443SCF51A.21, unknown, len: 285 aa. Similar to a number of hypothetical proteins e.g. Mycobacterium tuberculosis TR:P95220 (EMBL; Z86089) hypothetical 32.2 KD protein (300 aa), fasta scores opt: 714 z-score: 663.0 E(): 1.4e-29 45.3% identity in 289 aa overlap. Also similar in parts to Pseudomonas fluorescens TR:CAB48407 (EMBL; AJ243652) urea amidolyase homologue (1213 aa), fasta scores opt: 423 z-score: 390.1 E(): 2.3e-14 37.7% identity in 289 aa overlap. (285 aa)
SCO1407Hypothetical protein; SC6D7.32, unknown, len: > 1425 aa. Weakly similar to several including: Streptomyces coelicolor TR:Q9Z5A4(EMBL:AL035478) putative secreted protein SC2G5.19 (1156 aa), fasta scores opt: 327 z-score: 314.0 E(): 4.1e-10 28.0% identity in 938 aa overlap and Rhodobacter capsulatus TR:O68032(EMBL:AF010496) potential exonuclease (1238 aa), fasta scores opt: 439 z-score: 421.6 E(): 4.1e-16 28.8% identity in 1154 aa overlap. The predicted protein product of this CDS is alanine rich and contains multiple probable coiled-coils between residues: 369 to 401 (33 residues), 406 [...] (1553 aa)
SCO1408Putative membrane protein; SC6D7.31, possible membrane protein, len: 293 aa. Contains a possible membrane spanning hydrophobic domain. (293 aa)
SCO1409Putative membrane protein; SC6D7.30, possible membrane protein, len: 508 aa. Contains a possible membrane spanning hydrophobic domain and a probable coiled-coil between residues 259..286 (28 residues). (508 aa)
SCO1410SC6D7.29, putative GntR-family transcriptional regulator, len: 231 aa. Similar to many other regulators e.g. Bacillus licheniformis SW:GNTR_BACLI(EMBL:D31631) gluconate operon transcriptional repressor (P28 protein) (243 aa), fasta scores opt: 183 z-score: 234.8 E(): 1.1e-05 31.2% identity in 138 aa overlap and Chelatobacter heintzii SW:NTRA_CHEHE(EMBL:U39411) NTA operon transcriptional regulator (210 aa), fasta scores opt: 222 z-score: 284.0 E(): 1.9e-08 31.8% identity in 195 aa overlap. Contains a PS00043 Bacterial regulatory proteins, gntR family signature and a Pfam match to entry [...] (231 aa)
SCO1411SC6D7.28c, possible transmembrane transport protein, len: 440 aa. Highly similar to many other membrane transport proteins e.g. Escherichia coli SW:CIT1_ECOLI(EMBL:M11559) citrate-proton symporter (citrate transporter) (431 aa), fasta scores opt: 349 z-score: 368.9 E(): 3.6e-13 25.1% identity in 438 aa overlap and Yersinia pestis TR:Q9ZC42(EMBL:AL031866) putative transport protein (409 aa), fasta scores opt: 1363 z-score: 1421.9 E():0 49.5% identity in 410 aa overlap. Contains a Prosite hit to PS00217 Sugar transport proteins signature 2 and a Pfam match to entry PF00083 sugar_tr, Suga [...] (440 aa)
SCO1412Conserved hypothetical protein SC6D7.27c; SC6D7.27c, unknown, len: 277 aa. Highly similar to proteins of unknown function from Bacillus subtilis SW:YCSI_BACSU(EMBL:D38161) hypothetical 28.1 KD protein (257 aa), fasta scores opt: 945 z-score: 1112.7 E():0 52.5% identity in 255 aa overlap and Schizosaccharomyces pombe (Fission yeast) SW:YA01_SCHPO(EMBL:Z49811) hypothetical 33.8 KD protein (301 aa), fasta scores opt: 596 z-score: 703.6 E(): 8.1e-32 40.1% identity in 252 aa overlap.; Belongs to the D-glutamate cyclase family. (277 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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