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SCO0061 SCO0061 SCO0062 SCO0062 SCO0063 SCO0063 SCO0064 SCO0064 SCO0065 SCO0065 SCO0066 SCO0066 SCO0067 SCO0067 SCO0068 SCO0068 SCO0069 SCO0069 SCO0271 SCO0271 SCO0272 SCO0272 SCO0273 SCO0273 SCO0275 SCO0275 SCO0290 SCO0290 SCO0291 SCO0291 SCO0292 SCO0292 SCO0425 SCO0425 SCO0453 SCO0453 SCO0454 SCO0454 SCO0455 SCO0455 SCO0456 SCO0456 SCO0457 SCO0457 SCO0531 SCO0531 SCO0532 SCO0532 SCO0533 SCO0533 SCO0537 SCO0537 SCO0538 SCO0538 SCO0539 SCO0539 SCO0540 SCO0540 SCO0660 SCO0660 SCO0661 SCO0661 SCO0662 SCO0662 SCO0663 SCO0663 SCO0664 SCO0664 SCO0733 SCO0733 SCO0734 SCO0734 SCO0735 SCO0735 SCO0914 SCO0914 SCO0948 SCO0948 SCO0949 SCO0949 SCO0950 SCO0950 SCO0951 SCO0951 SCO0952 SCO0952 SCO0953 SCO0953 SCO1049 SCO1049 SCO1055 SCO1055 SCO1056 SCO1056 SCO1057 SCO1057 SCO1058 SCO1058 SCO1062 SCO1062 SCO1063 SCO1063 SCO1064 SCO1064 SCO1065 SCO1065 SCO1066 SCO1066 SCO1067 SCO1067 SCO1537 SCO1537 SCO1538 SCO1538 SCO1539 SCO1539 SCO1707 SCO1707 SCO1878 SCO1878 SCO1882 SCO1882 SCO1884 SCO1884 SCO1885 SCO1885 SCO1886 SCO1886 SCO1887 SCO1887 SCO1891 SCO1891 SCO1892 SCO1892 SCO1894 SCO1894 SCO1896 SCO1896 SCO1898 SCO1898 SCO1899 SCO1899 SCO1900 SCO1900 SCO1901 SCO1901 SCO1902 SCO1902 SCO2229 SCO2229 SCO2230 SCO2230 SCO2231 SCO2231 SCO2431 SCO2431 SCO2432 SCO2432 SCO2433 SCO2433 SCO2434 SCO2434 SCO2435 SCO2435 SCO2436 SCO2436 SCO2437 SCO2437 SCO2438 SCO2438 SCO2750 SCO2750 SCO2751 SCO2751 SCO2752 SCO2752 SCO2753 SCO2753 SCO2754 SCO2754 SCO2795 SCO2795 SCO2796 SCO2796 SCO2797 SCO2797 SCO2944 SCO2944 SCO2945 SCO2945 SCO2946 SCO2946 SCO3482 SCO3482 SCO3483 SCO3483 SCO3484 SCO3484 SCO3503 SCO3503 SCO3504 SCO3504 SCO3505 SCO3505 SCO4240 SCO4240 SCO5232 SCO5232 SCO5233 SCO5233 SCO5234 SCO5234 SCO5427 SCO5427 SCO5428 SCO5428 SCO5429 SCO5429 SCO5430 SCO5430 SCO6004 SCO6004 SCO6005 SCO6005 SCO6006 SCO6006 SCO6007 SCO6007 SCO6008 SCO6008 SCO6086 SCO6086 SCO6087 SCO6087 SCO6088 SCO6088 SCO6089 SCO6089 SCO6090 SCO6090 SCO6229 SCO6229 SCO6230 SCO6230 SCO6231 SCO6231 SCO6232 SCO6232 SCO6233 SCO6233 SCO6600 SCO6600 SCO6601 SCO6601 SCO6602 SCO6602 SCO6603 SCO6603 SCO7011 SCO7011 SCO7012 SCO7012 SCO7013 SCO7013 SCO7014 SCO7014 SCO7015 SCO7015 SCO7016 SCO7016 SCO7017 SCO7017 SCO7027 SCO7027 SCO7028 SCO7028 SCO7029 SCO7029 SCO7030 SCO7030 SCO7031 SCO7031 SCO7165 SCO7165 SCO7166 SCO7166 SCO7405 SCO7405 SCO7406 SCO7406 SCO7408 SCO7408 SCO7409 SCO7409 SCO7410 SCO7410 SCO7411 SCO7411 SCO7484 SCO7484 SCO7485 SCO7485 SCO7486 SCO7486 SCO7487 SCO7487 SCO7488 SCO7488 SCO7489 SCO7489 SCO7490 SCO7490 SCO7491 SCO7491 SCO7492 SCO7492 SCO7493 SCO7493 SCO7502 SCO7502 SCO7503 SCO7503 SCO7504 SCO7504 SCO7505 SCO7505 SCO7555 SCO7555 SCO7556 SCO7556 SCO7557 SCO7557
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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SCO0061Conserved hypothetical protein; SCJ4.42c, unknown, len: 434 aa; similar to SW:YDEG_SCHPO hypothetical protein from Schizosaccharomyces pombe (fission yeast) (509 aa) fasta scores; opt: 665, z-score: 791.0, E(): 0, (37.6% identity in 423 aa overlap) and to TR:Q9KEQ9 (EMBL:AP001509) Bacillus halodurans BH0790 protein, 454 aa; fasta scores: opt: 1262 Z-score: 1468.0 bits: 280.8 E(): 3.9e-74; 45.433% identity in 416 aa overlap. (434 aa)
SCO0062SCJ4.43c, probable LacI family transcriptional regulator, len: 367 aa; similar to many transcriptional regulators e.g. SW:GALR_ECOLI galactose operon repressor (343 aa) fasta scores; opt: 549, z-score: 636.2, E(): 4.5e-28, (32.5% identity in 332 aa overlap). Contains Pfam matches to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family and entry PF00356 lacI, Bacterial regulatory proteins, lacI family. Contains possible helix-turn-helix motif (+3.86 SD) 26-47. (367 aa)
SCO0063SCJ4.44c, possible glucokinase, len: 311 aa; similar to many eg. SW:GLK_STRCO glucokinase from Streptomyces coelicolor (317 aa) fasta scores; opt: 175, z-score: 195.7, E(): 0.0015, (28.2% identity in 326 aa overlap). Contains Pfam match to entry PF00480 ROK, ROK family. (311 aa)
SCO0064Hypothetical protein; SCJ4.45c, unknown, len: 572 aa. (572 aa)
SCO0065SCJ4.46, possible extracellular binding protein, part of a possible binding protein dependent transport system, len: 437 aa; similar to many egs. TR:Q9Z492 (EMBL:AF043654) BxlE, extracellular binding protein from Streptomyces lividans (434 aa) fasta scores; opt: 256, z-score: 290.5, E(): 8.1e-09, (23.3% identity in 446 aa overlap) and SW:YC14_PYRHO hypothetical ABC transporter extracellular binding protein from Pyrococcus horikoshii OT3 (441 aa) fasta scores; opt: 348, z-score: 393.3, E(): 1.5e-14, (25.4% identity in 343 aa overlap). Contains Prosite match to PS00013 Prokaryotic membra [...] (437 aa)
SCO0066SCJ4.47, possible integral membrane permease, part of a possible binding protein dependent transport system, len: 319 aa; similar to many eg. SW:LACF_AGRRD lactose transport system permease from Agrobacterium radiobacter (298 aa) fasta scores; opt: 460, z-score: 522.1, E(): 1e-21, (30.5% identity in 272 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. (319 aa)
SCO0067SCJ4.48, probable integral membrane permease, len: 273 aa; similar to many e.g. TR:Q9Z3R7 (EMBL:AF045609) putative inner membrane permease from the alpha-glucosides binding protein dependent transport system of Rhizobium (Sinorhizobium) meliloti (305 aa) fasta scores; opt: 393, z-score: 457.6, E(): 4e-18, (32.3% identity in 229 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains possible membrane spanning hydrophobic regions. (273 aa)
SCO0068SCJ4.49, possible hydrolase (putative secreted protein), len: 401aa; N-terminal region similar to that of TR:Q9Z4P9 (EMBL:AB024331) alpha-1,6-D-mannanase from Bacillus circulans (589 aa) fasta scores; opt: 218, z-score: 251.2, E(): 1.2e-06, (26.2% identity in 229 aa overlap). (401 aa)
SCO0069Hypothetical protein; SCJ4.50, unknown, len: 1052 aa. (1052 aa)
SCO0271SCF1.13, possible binding-protein-dependent transport protein, len: 317aa; similar to many predicted membrane transporters eg. TR:CAB41203 (EMBL:AL049661) putative binding-protein-dependent transport protein from Streptomyces coelicolor (327 aa) fasta scores; opt: 624, z-score: 720.7, E(): 8.8e-33, (35.9% identity in 320 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible membrane spanning hydrophobic [...] (317 aa)
SCO0272SCF1.14, possible binding-protein-dependent transport protein, len: 296aa; similar to many predicted membrane transporters eg. TR:O53483 (EMBL:AL021899) sugar transport protein from Mycobacterium tuberculosis (280 aa) fasta scores; opt: 594, z-score: 708.0, E(): 4.5e-32, (34.6% identity in 283 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible membrane spanning hydrophobic regions. (296 aa)
SCO0273Putative substrate binding protein; SCF85.01, unknown, partial CDS, len: >264 aa. Weakly similar to several hypotheticals e.g. Mycobacterium tuberculosis TR:O53485 (EMBL; AL021899) lipoprotein component of sugar transport system (439 aa), fasta scores opt: 258 z-score: 307.2 E(): 9.3e-10 27.9% identity in 222 aa overlap and Thermotoga maritima TR:AAD35892 (EMBL; AE001748) sugar ABC transporter, periplasmic sugar-binding protein TM0810 (420 aa), fasta scores opt: 169 z-score: 203.2 E(): 0.00058 25.1% identity in 263 aa overlap; SCF1.15, partial CDS, possible substrate binding protein (e [...] (449 aa)
SCO0275SCF85.03, possible transcriptional repressor protein, len: 385 aa. Low similarity to many repressor proteins e.g. Anaerocellum thermophilum SW:XYLR_ANATH (EMBL; Z69782)xylose repressor (399 aa), fasta scores opt: 325 z-score: 375.7 E(): 1.4e-13 23.3% identity in 395 aa overlap and Streptomyces coelicolor TR:O50502 (EMBL; AL009199) probable transcriptional repressor protein SC7B7.05 (403 aa), fasta scores opt: 402 z-score: 463.7 E(): 1.8e-18 29.7% identity in 404 aa overlap. Contains a Pfam match to entry PF00480 ROK, ROK family and has a possible helix turn helix motif between aa 30..51. (385 aa)
SCO0290SCF85.18, probable solute-binding protein, len: 436 aa. Similar to many including: Streptomyces lividans TR:Q9Z492 (EMBL; AF043654) BxlE precursor (434 aa), fasta scores opt: 946 z-score: 1058.6 E(): 0 33.7% identity in 427 aa overlap and Streptococcus mutans SW:MSME_STRMU (EMBL; M77351) multiple sugar-binding protein precursor MsmE (420 aa), fasta scores opt: 258 z-score: 291.6 E(): 6.9e-09 24.2% identity in 351 aa overlap. Contains a Pfam match to entry PF01547 SBP_bacterial_1, PS00013 Prokaryotic membrane lipoprotein lipid attachment site and a PS00017 ATP/GTP-binding site motif A ( [...] (436 aa)
SCO0291SCF85.19, possible binding protein dependent transport protein, len: 300 aa. Similar to many including: Streptomyces lividans TR:Q9ZI17 (EMBL; AF043654) BxlF (317 aa), fasta scores opt: 873 z-score: 1049.2 E(): 0 44.0% identity in 298 aa overlap and Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661)putative binding protein dependent transport protein SCE134.05C (327 aa), fasta scores opt: 551 z-score: 664.3 E(): 1.2e-29 32.7% identity in 294 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and a PS0040 [...] (300 aa)
SCO0292SC5G9.01, probable sugar ABC-transporter integral membrane protein, partial CDS, len: >148 aa; similar to e.g. TR:O51925 (EMBL:AF012836), malG, Thermococcus litoralis inner membrane protein from trehalose/maltose ABC-transporter system (278 aa), fasta scores; opt: 296 z-score: 384.7 E(): 4.6e-14, 32.2% identity in 146 aa overlap. Also similar to many putative ABC-transporter components e.g. SW:YOR2_CALSR (EMBL:L18965) Caldicellulosiruptor sp. (strain Rt8B.4) putative membrane bound sugar transport protein ORF2 (275 aa) (43.0% identity in 142 aa overlap). Contains hydrophobic, possible [...] (298 aa)
SCO0425Hypothetical protein SCF51A.03c; SCF51A.03c, unknown, len: 316 aa. Similar to Streptomyces coelicolor TR:CAB46385 (EMBL; AL096743) hypothetical 30.5 KD protein SCI7.02C (281 aa), fasta scores opt: 424 z-score: 490.6 E(): 5.7e-20 36.6% identity in 292 aa overlap. (316 aa)
SCO0453SCF51A.31, probable secreted solute-binding lipoprotein, len: 429 aa. Weakly similar to many putative solute-binding proteins e.g. Bacillus subtilis SW:YURO_BACSU (EMBL; Z99120) hypothetical ABC transporter extracellular binding protein YurO (422 aa), fasta scores opt: 235 z-score: 270.1 E(): 1.1e-07 19.9% identity in 422 aa overlap. Contains a Pfam match to entry PF01547 SBP_bacterial_1, an appropriately positioned Prosite hit to PS00013, a prokaryotic membrane lipoprotein lipid attachment site and also contains a possible N-terminal signal sequence. (429 aa)
SCO0454SCF51A.32, probable binding-protein dependent transport protein, len: 313 aa. Similar to many including: Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661) putative protein SCE134.05C (327 aa), fasta scores opt: 479 z-score: 546.7 E(): 4.3e-23 31.4% identity in 315 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and a Prosite hit to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains multiple possible membrane spanning hydrophobic domains. (313 aa)
SCO0455SCF51A.33, putative binding-protein dependent transport protein, len: 274 aa. Similar to many e.g. Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) TR:O30833 (EMBL; AF018073) sorbitol/mannitol transport inner membrane protein (276 aa), fasta scores opt: 452 z-score: 556.9 E(): 1.2e-23 32.0% identity in 272 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains multiple possible membrane spanning hydrophobic domains. (275 aa)
SCO0456SCF51A.34, possible LacI family transcriptional regulator, len: 347 aa. Highly similar to several including: Escherichia coli SW:CYTR_ECOLI (EMBL; X03683) transcriptional repressor CytR (341 aa), fasta scores opt: 504 z-score: 574.2 E(): 1.3e-24 31.6% identity in 339 aa overlap and Streptomyces coelicolor TR:O86598 (EMBL; AL031514) putative transcriptional regulator SC2H4.15 (342 aa), fasta scores opt: 807 z-score: 915.3 E(): 0 44.4% identity in 333 aa overlap. Contains a Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, a Pfam match to entry PF00532 Peripla [...] (347 aa)
SCO0457Conserved hypothetical protein SCF51A.35; SCF51A.35, unknown, len: 644 aa; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (644 aa)
SCO0531SCF11.11, probable sugar transporter sugar binding protein, len: 422 aa; similar to TR:P72397 (EMBL:Y07706) Streptomyces coelicolor MalE, putative maltose-binding protein, 423 aa; fasta scores: opt: 367 z-score: 390.0 E(): 2.4e-14; 27.2% identity in 419 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, bacterial extracellular solute-binding protein and a prosite match correctly situated to entry PS00013 prokaryotic membrane lipoprotein lipid attachment site. Contains probable N-terminal signal sequence. (422 aa)
SCO0532SCF11.12, probable sugar transporter membrane protein, len: 302 aa; similar to TR:CAB55533 (EMBL:Y07706) Streptomyces coelicolor inner membrane protein MalF, 300 aa; fasta scores: opt: 493 z-score: 600.8 E(): 4.3e-26; 32.6% identity in 291 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and a prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature. (302 aa)
SCO0533SCF11.13, possible sugar transporter membrane protein, len: 285 aa; similar to TR:CAB46387 (EMBL:AL096743) Streptomyces coelicolor putative integral membrane transport protein MalG, 296 aa; fasta scores: opt: 538 z-score: 675.0 E(): 3.2e-30; 33.7% identity in 279 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature. (285 aa)
SCO0537SCF11.17, hypothetical secreted protein, len: 275 aa; highly similar to TR:P95755 (EMBL:D89734) Streptomyces griseus hypothetical protein adjacent to SgaA, 258 aa; fasta scores: opt: 858 z-score: 936.4 E(): 0; 54.9% identity in 264 aa overlap and to TR:CAB51262 (EMBL:AL096872) Streptomyces coelicolor putative endo alpha-1,4 polygalactosaminidase SC5F7.23c, 282 aa; fasta scores: opt: 303 z-score: 336.5 E(): 2.3e-11; 33.6% identity in 223 aa overlap. Contains probable N-terminal signal sequence. (275 aa)
SCO0538SCF11.18, probable sugar transporter sugar binding lipoprotein, len: 449 aa; similar to TR:AAD35680 (EMBL:AE001734) Thermotoga maritima putative sugar ABC transporter periplasmic sugar-binding protein TM0595, 419 aa; fasta scores: opt: 333 z-score: 361.2 E(): 9.5e-13; 24.1% identity in 406 aa overlap. Contains a Pfam match to entry PF01547 SBP_bacterial_1, bacterial extracellular solute-binding protein and probable N-terminal signal sequence. (442 aa)
SCO0539SCF11.19, probable sugar transporter membrane protein, len: 316 aa; similar to TR:CAB52981 (EMBL:AL109950) Streptomyces coelicolor putative integral membrane permease, 319 aa; fasta scores: opt: 606 z-score: 689.2 E(): 5.1e-31; 34.9% identity in 312 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and a prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature. Contains probable N-terminal signal sequence. (316 aa)
SCO0540SCF11.20, probable sugar transport membrane protein, len: 299 aa; similar to TR:Q06111 (EMBL:X66092) Clostridium perfringens putative transport system permease protein, 275 aa; fasta scores: opt: 704 z-score: 838.6 E(): 0; 38.4% identity in 255 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and a prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature. Contains porbable N-terminal signal sequence. (299 aa)
SCO0660SCF91.20, probable solute-binding lipoprotein, len: 443 aa. Similar to several solute-binding proteins e.g. Agrobacterium radiobacter SW:LACE_AGRRD(EMBL:X66596) lactose-binding protein precursor (422 aa), fasta scores opt: 270 z-score: 303.1 E(): 1.6e-09 23.5% identity in 387 aa overlap and Streptomyces coelicolor TR:P72397(EMBL:Y07706) putative maltose-binding protein MalE (423 aa), fasta scores opt: 345 z-score: 386.1 E(): 4e-14 25.5% identity in 459 aa overlap. Contains a Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein. Also contains an ap [...] (443 aa)
SCO0661SCF91.21, possible binding protein dependent transport protein, len: 328 aa. Similar to many membrane transport proteins e.g. Escherichia coli SW:UGPA_ECOLI(EMBL:X13141) SN-glycerol-3-phosphate transport system permease protein (295 aa), fasta scores opt: 393 z-score: 465.7 E(): 1.5e-18 28.7% identity in 282 aa overlap and Streptomyces coelicolor TR:CAB41203(EMBL:AL049661) putative binding protein dependent transport protein (327 aa), fasta scores opt: 452 z-score: 533.8 E(): 2.4e-22 28.2% identity in 326 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-de [...] (328 aa)
SCO0662SCF91.22, possible binding protein dependent transport protein, len: 287 aa. Similar to many membrane transport proteins e.g. Agrobacterium radiobacter SW:LACG_AGRRD(EMBL:X66596) lactose transport system permease protein (273 aa), fasta scores opt: 439 z-score: 546.1 E(): 4.8e-23 28.5% identity in 267 aa overlap and Bacillus subtilis TR:O05095(EMBL:X89810) putative integral protein (281 aa), fasta scores opt: 480 z-score: 596.3 E(): 7.7e-26 30.8% identity in 266 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane com [...] (287 aa)
SCO0663Putative 2-hydroxyacid-family dehydrogenase; SCF91.23, possible 2-hydroxyacid-family dehydrogenase, len: 343 aa. Similar in parts to several D-3-phosphoglycerate dehydrogenases e.g. Mycobacterium tuberculosis SW:SERA_MYCTU (EMBL:AL021287) (528 aa), fasta scores opt: 450 z-score: 536.4 E(): 1.7e-22 34.1% identity in 261 aa overlap. Also similar to Streptomyces coelicolor TR:CAB55710(EMBL:AL117387) possible dehydrogenase SCF41.07 (339 aa), fasta scores opt: 927 z-score: 1106.0 E(): 0 48.6% identity in 325 aa overlap. Contains a Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2- [...] (343 aa)
SCO0664SCF91.24, hypothetical protein, len: 631 aa; similar to TR:CAC48915 (EMBL:AL603643) Rhizobium meliloti (Sinorhizobium meliloti) hypothetical protein SMB20536, 617 aa; fasta scores: opt: 524 Z-score: 553.7 E(): 3.3e-23; 30.182% identity in 550 aa overlap. (631 aa)
SCO07333SC5B7.11c, hypothetical protein, len: 61 aa; similar to TR:Q9K3Z9 (EMBL:AL359949) Streptomyces coelicolor hypothetical 6.5 kDa protein 2SCG61.16, 59 aa; fasta scores: opt: 196 z-score: 304.8 E(): 1.9e-09; 59.3% identity in 54 aa overlap. (61 aa)
SCO07343SC5B7.12c, probable transcriptional repressor, len: 424 aa; similar to SW:MLC_ECOLI (EMBL:D32222) Escherichia coli transcriptional regulator Mlc protein, 406 aa; fasta scores: opt: 387 z-score: 414.7 E(): 1.4e-15; 24.1% identity in 344 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and possible helix-turn-helix motif at residues 64..85 (+6.19 SD). (424 aa)
SCO07353SC5B7.13, possible oxidoreductase, len: 400 aa; low similarity to TR:Q9KDG5 (EMBL:AP001511) Bacillus halodurans NADH-dependent dehydrogenase BH1248, 340 aa; fasta scores: opt: 243 z-score: 286.8 E(): 1.9e-08; 24.8% identity in 242 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (400 aa)
SCO0914SCM10.02c, possible lipoprotein, len: 422 aa; similar to TR:CAB59588 (EMBL:AL132662) Streptomyces coelicolor putative sugar transporter sugar binding protein SCF11.11, 422 aa; fasta scores: opt: 1543 z-score: 1682.7 E(): 0; 57.6% identity in 427 aa overlap and to SW: MALE_ENTAE Enterobacter aerogenes maltose-binding periplasmic protein precursor MalE, 396 aa; fasta scores: opt: 224 z-score: 248.5 E(): 1.9e-06; 23.9% identity in 427 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and match correctly situated to Prosite ent [...] (422 aa)
SCO0948SCM11.03c, possible alpha-mannosidase, len: 1007 aa; similar to TR:AAC00190 (EMBL:AF044414) Homo sapiens alpha-mannosidase 6A8B, 1062 aa; fasta scores: opt: 1326 z-score: 1446.5 E(): 0; 37.8% identity in 1013 aa overlap and to SW:MAN1_RAT (EMBL:M57547) Rattus norvegicus alpha-mannosidase (EC 3.2.1.24), 1040 aa; fasta scores: opt: 1285 z-score: 1401.8 E(): 0; 35.9% identity in 1041 aa overlap. (1007 aa)
SCO0949SCM11.04c, hypothetical protein, len: 415 aa; similar to TR:CAB56687 (EMBL:AL121596) Streptomyces coelicolor hypothetical 71.4 kD protein SCF51A.35, 644 aa; fasta scores: opt: 205 z-score: 234.7 E(): 1.1e-05; 26.0% identity in 408 aa overlap; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (415 aa)
SCO0950SCM11.05c, probable transport system permease protein, len: 306 aa; similar to TR:P73854 (EMBL:D90910) Synechocystis sp. lactose transport system permease protein LacG, 270 aa; fasta scores: opt: 688 z-score: 826.9 E(): 0; 39.2% identity in 273 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. (306 aa)
SCO0951SCM11.06c, probable transport system permease protein, len: 310 aa; similar to TR:P73352 (EMBL:D90905) Synechocystis sp. lactose transport system permease protein LacF, 298 aa; fasta scores: opt: 750 z-score: 885.7 E(): 0; 44.9% identity in 292 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and to prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. (310 aa)
SCO0952SCM11.07c, possible solute-binding protein, len: 430 aa; similar to TR:P73325 (EMBL:D90905) Synechocystis sp SrrA, 433 aa; fasta scores: opt: 611 z-score: 678.3 E(): 2.1e-30; 29.8% identity in 430 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and possible N-terminal region signal peptide sequence. (430 aa)
SCO0953SCM11.08, probable lacI-family transcriptional regulator, len: 349 aa; similar to TR:O86598 (EMBL:AL031514) Streptomyces coelicolor putative transcriptional regulator, SC2H4.15, 342 aa; fasta scores opt: 949 z-score: 1067.0 E(): 0; 44.6% identity in 341 aa overlap and to SW:ASCG_ECOLI (EMBL:M73326) Escherichia coli cryptic asc operon repressor, 336 aa; fasta scores: opt: 409 z-score: 463.9 E(): 1.8e-18; 28.4% identity in 334 aa overlap. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family, score 37.90, E-value 3.1e-09 and PF00532 Peripla_BP_like, Pe [...] (349 aa)
SCO1049SCG20A.29c, probable secreted oxidoreductase, len: 387 aa; similar to SW:GFO_ZYMMO (EMBL:M97379) Zymomonas mobilis glucose-fructose oxidoreductase precursor (EC 1.1.99.28) Gfo, 439 aa; fasta scores: opt: 287 z-score: 318.4 E(): 2.9e-10; 26.6% identity in 350 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family and possible N-terminal region signal peptide sequence. (387 aa)
SCO1055Putative sugar hydrolase; SCG22.01c, probable hydrolase (fragment), len: >346 aa; similar to N-terminal part of TR:P96793 (EMBL:U89276) Lactobacillus pentosus alpha-xylosidase XylQ, 762 aa; fasta scores: opt: 1174 z-score: 1386.0 E(): 0; 50.0% identity in 346 aa overlap. Contains Pfam match to entry PF01055 Glyco_hydro_31, Glycosyl hydrolases family 31; SCG20A.35c, probable sugar hydrolase (fragment), len: >443 aa; similar to TR:P96793 (EMBL:U89276) Lactobacillus pentosus alpha-xylosidase XylQ, 762 aa; fasta scores: opt: 1319 z-score: 1518.7 E(): 0; 47.1% identity in 437 aa overlap. Co [...] (756 aa)
SCO1056SCG22.02, possible sugar transport sugar binding protein, len: 419 aa; similar to TR:CAB90879 (EMBL:AL355752) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa; fasta scores: opt: 433 z-score: 507.0 E(): 9.2e-21; 28.7% identity in 380 aa overlap and to SW:MALX_STRPN (EMBL:L08611) Streptococcus pneumoniae maltose/maltodextrin-binding protein precursor MalX, 423 aa; fasta scores: opt: 255 z-score: 299.6 E(): 3.3e-09; 23.9% identity in 372 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and correctly situ [...] (419 aa)
SCO1057SCG22.03, possible sugar transport integral membrane protein, len: 321 aa; similar to TR:Q9RK91 (EMBL:AL117322) Streptomyces coelicolor putative binding-protein-dependent transport protein SCF1.13, 317 aa; fasta scores: opt: 681 z-score: 798.6 E(): 0; 35.0% identity in 317 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (321 aa)
SCO1058SCG22.04, possible sugar transport integral membrane protein, len: 275 aa; similar to TR:Q9RUF0 (EMBL:AE001988) Deinococcus radiodurans ABC transporter, permease protein, MalFG family, DR1436 aa; fasta scores: opt: 550 z-score: 629.9 E(): 1.3e-27; 32.9% identity in 283 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (275 aa)
SCO1062SCG22.08c, possible hydrolase, len: 693 aa; similar to SW:BGLR_ECOLI (EMBL:M14641) Escherichia coli beta-glucuronidase (EC 3.2.1.31) GusA, 603 aa; fasta scores: opt: 386 z-score: 439.2 E(): 5.5e-17; 25.3% identity in 582 aa overlap and to TR:Q9RIU6 (EMBL: AL133278) Streptomyces coelicolor putative hydrolase SCM11.15c, 872 aa; fasta scores: opt: 977 z-score: 1111.4 E(): 0; 37.1% identity in 596 aa overlap; Belongs to the glycosyl hydrolase 2 family. (693 aa)
SCO1063SCG22.09c, possible sugar transport integral membrane protein, len: 297 aa; similar to SW:LACG_AGRRD (EMBL:X66596) Agrobacterium radiobacter lactose transport system permease protein LacG, 273 aa; fasta scores: opt: 514 z-score: 627.5 E(): 1.8e-27; 35.1% identity in 282 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains also possible hydrophobic membrane spanning regions. (297 aa)
SCO1064SCG22.10c, probable sugar transport integral membrane protein, len: 311 aa; similar to TR:AAF37728 (EMBL:AF086819) Thermomonospora fusca cellobiose transport permease BglA, 302 aa; fasta scores: opt: 664 z-score: 802.8 E(): 0; 38.6% identity in 280 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (311 aa)
SCO1065SCG22.11c, possible sugar transport sugar binding protein, len: 453 aa; similar to SW:LACE_AGRRD (EMBL:X66596) Agrobacterium radiobacter lactose-binding protein precursor LacE, 422 aa; fasta scores: opt: 273 z-score: 296.9 E(): 4.6e-09; 23.8% identity in 420 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and possible N-terminal region signal peptide sequence. (453 aa)
SCO1066SCG22.12, probable lacI-family transcriptional regulator, len: 340 aa; similar to SW:CYTR_ECOLI (EMBL:X03683) Escherichia coli transcriptional repressor CytR, 341 aa; fasta scores: opt: 608 z-score: 692.2 E(): 4.4e-31; 34.2% identity in 339 aa overlap. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family and match to Prosite entry PS00356 Bacterial regulatory proteins, lacI family signature and possible helix-turn-helix motif at residues 4..25 (+6.04 SD). (340 aa)
SCO1067SCG22.13, possible integral membrane transport protein, len: 390 aa; similar to TR:Q9RRI8 (EMBL:AE002079) Deinococcus radiodurans transport protein, putative DR2502, 471 aa; fasta scores: opt: 774 z-score: 797.8 E(): 0; 40.3% identity in 387 aa overlap. Contains possible hydrophobic membrane spanning regions. (390 aa)
SCO1537SCL2.27c, probable transport system membrane protein, len: 303 aa; similar to SW:YESQ_BACSU (EMBL:Z99107) Bacillus subtilis probable ABC transporter permease protein YesQ, 296 aa; fasta scores:opt: 868 z-score: 1048.4 E(): 0; 45.1% identity in 295 aa overlap and to TR:CAB59597 (EMBL:AL132662) Streptomyces coelicolor probable sugar transport inner membrane protein SCF11.20, 299 aa; fasta scores: opt: 636 z-score: 769.8 E(): 0; 37.7% identity in 308 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match [...] (303 aa)
SCO1538SCL2.28c, probable transport system membrane protein, len: 328 aa; similar to SW:YESP_BACSU (EMBL:Z99107) Bacillus subtilis probable ABC transporter permease protein YesP, 309 aa; fasta scores: opt: 1013 z-score: 1146.0 E(): 0; 48.8% identity in 301 aa overlap and to TR:CAB59596 (EMBL:AL132662) Streptomyces coelicolor probable sugar transporter inner membrane protein SCF11.19, 316 aa; fasta scores: opt: 608 z-score: 690.8 E(): 4.4e-31; 32.8% identity in 320 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component [...] (328 aa)
SCO1539Putative lipoprotein; SCL2.29c, possible secreted protein, len: 433 aa; similar to TR:O31518 (EMBL:Z99107) Bacillus subtilis YesO protein, 412 aa; fasta scores: opt: 606 z-score: 680.7 E(): 1.7e-30; 27.7% identity in 411 aa overlap and to TR:CAB59595 (EMBL:AL132662) Streptomyces coelicolor probable sugar transporter sugar binding lipoprotein SCF11.18, 442 aa; fasta scores: opt: 312 z-score: 352.1 E(): 3.4e-12; 24.4% identity in 454 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and match to Prosite entry PS00013 Prokaryo [...] (433 aa)
SCO1707SCI30A.28c, probable ABC sugar transporter, ATP-binding subunit, len: 445aa; similar to many eg. TR:AAD24578 (EMBL:AF126010) trehalose/maltose transport ATP-hydrolysing subunit from hyperthermophilic archaeon Thermococcus litoralis (372 aa) fasta scores; opt: 975, z-score: 1068.2, E(): 0, (50.1% identity in 335 aa overlap). Contains Pfam match to entry PF00005 ABC_tran, ABC transporter and Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). (445 aa)
SCO1878SCI39.25c, possible secreted protein, len: 265 aa. Contains possible N-terminal region signal peptide sequence. (265 aa)
SCO1882SCI39.29c, probable secreted sugar-binding protein, len: 452 aa; similar to TR:P72397 (EMBL:Y07706) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa; fasta scores: opt: 433 Z-score: 459.6 bits: 94.2 E(): 5.2e-18; 30.716% identity in 433 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and possible N-terminal region signal peptide sequence. (452 aa)
SCO1884Hypothetical protein; SCI7.02c, unknown, len: 281aa. (281 aa)
SCO1885SCI7.03c, possible oxidoreductase, len: 385 aa; similar to many proteins of undefined function eg. TR:Q45376 (EMBL:X90711) from a locus required for lipopolysaccharide biosynthesis in Bordetella pertussis (350 aa) fasta scores; opt: 232, z-score: 266.7, E(): 1.6e-07, (28.0% identity in 275 aa overlap). Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (385 aa)
SCO1886SCI7.04c, possible integral membrane transport protein, len: 298aa; similar to many eg. SW:YURM_BACSU hypothetical ABC transporter from Bacillus subtilis (300 aa) fasta scores; opt: 582, z-score: 650.2, E(): 6.9e-29, (31.7% identity in 293 aa overlap) and TR:O87858 (EMBL:AL031013) putative transmembrane sugar transport protein from Streptomyces coelicolor (279 aa) fasta scores; opt: 540, z-score: 604.3, E(): 2.5e-26, (34.7% identity in 277 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match [...] (298 aa)
SCO1887SCI7.05c, possible integral membrane transport protein, len: 298aa; similar to many eg. TR:O51924 (EMBL:AF012836) inner membrane protein, MalF from the trehalose/maltose transport system of the hyperthermophilic archaeon Thermococcus litoralis (300 aa) fasta scores; opt: 681, z-score: 814.3, E(): 0, (37.5% identity in 285 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible membrane spanni [...] (311 aa)
SCO1891SCI7.09c, hypothetical protein, len: 199 aa; similar to TR:P71985 (EMBL:Z81360) hypothetical protein from Mycobacterium tuberculosis (189 aa) fasta scores; opt: 210, z-score: 248.3, E(): 1.7e-06, (32.4% identity in 182 aa overlap). (199 aa)
SCO1892SCI7.10, possible integral membrane efflux protein, len: 415aa; similar to many egs. TR:CAB41206 (EMBL:AL049661) putative integral membrane efflux protein from Streptomyces coelicolor (500 aa) fasta scores; opt: 347, z-score: 354.0, E(): 2.2e-12, (29.7% identity in 408 aa overlap) and SW:TCR3_ECOLI tetracycline resistance protein from Escherichia coli (396 aa) fasta scores; opt: 241, z-score: 249.6, E(): 1.4e-06, (25.9% identity in 398 aa overlap). Contains possible membrane spanning hydrophobic regions. (415 aa)
SCO1894SCI7.12c, alanine-rich protein, len: 390aa. (390 aa)
SCO1896Conserved hypothetical protein; SCI7.14, unknown, len: 269aa; similar to many eg. SW:YTBQ_BACSU hypothetical protein from Bacillus subtilis (253 aa) fasta scores; opt: 262, z-score: 310.1, E(): 6.1e-10, (27.8% identity in 241 aa overlap). (269 aa)
SCO1898SCI7.16, possible sugar binding protein, len: 456aa; similar to many eg. TR:O30831 (EMBL:AF018073) periplasmic sorbitol binding protein from Rhodobacter sphaeroides (436 aa) fasta scores; opt: 1203, z-score: 1347.3, E(): 0, (42.8% identity in 423 aa overlap). Contains possible N-terminal signal sequence. (456 aa)
SCO1899SCI7.17, possible integral membrane sugar transport protein, len: 314aa; similar to many eg. TR:O30832 (EMBL:AF018073) sorbitol/mannitol transport inner membrane protein from Rhodobacter sphaeroides (290 aa) fasta scores; opt: 722, z-score: 829.0, E(): 0, (40.6% identity in 276 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible membrane spanning hydrophobic regions. (314 aa)
SCO1900SCI7.18, possible integral membrane sugar transport protein, len: 292aa; similar to many eg. TR:O30833 (EMBL:AF018073) sorbitol/mannitol transport inner membrane protein from Rhodobacter sphaeroides (276 aa) fasta scores; opt: 659, z-score: 770.4, E(): 0, (40.6% identity in 276 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Also contains possible membrane spanning hydrophobic regions. (292 aa)
SCO1901SCI7.19, probable zinc-binding dehydrogenase, len: 329 aa; similar to many e.g. SW:DHSO_BACSU sorbitol dehydrogenase from Bacillus subtilis (352 aa) fasta scores; opt: 552, z-score: 626.6, E(): 1.4e-27, (30.1% identity in 345 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite match to PS00059 Zinc-containing alcohol dehydrogenases signature. (329 aa)
SCO1902Hypothetical hydrophilic protein; SCI7.20, unknown, hydrophilic, len: 129aa. (129 aa)
SCO2229SC10B7.24c, malG, putative maltose permease, len: 303 aa; identical to previously sequenced TR:P72399 (EMBL:Y07706) Streptomyces coelicolor putative maltose permease MalG, 302 aa and similar to SW:MALG_ECOLI (EMBL:X02871) Escherichia coli maltose transport system permease protein MalG, 296 aa; fasta scores: opt: 476 z-score: 570.0 E(): 2.3e-24; 34.1% identity in 293 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane [...] (303 aa)
SCO2230SC10B7.25c, malF, putative maltose permease, len: 334 aa; identical to previously sequenced TR:P72398 (EMBL:Y07706) Streptomyces coelicolor putative maltose permease MalF, 334 aa and similar to SW:MALF_ECOLI (EMBL:J01648) Escherichia coli maltose transport system permease protein MalF, 514 aa; fasta scores: opt: 424 z-score: 504.4 E(): 1e-20; 33.9% identity in 239 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane c [...] (334 aa)
SCO2231SC10B7.26c, malE, putative maltose-binding protein, len: 423 aa; identical to previously sequenced TR:P72397 (EMBL:Y07706) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa and similar to SW:MALX_STRPN (EMBL:L08611) Streptococcus pneumoniae maltose/maltodextrin-binding protein precursor MalX, 423 aa; fasta scores: opt: 431 z-score: 470.1 E(): 8.4e-19; 28.1% identity in 434 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and two matches to Prosite entries PS00013 Prokaryotic membrane lipoprotein lipid a [...] (423 aa)
SCO2431SCC24.02c, abfA, alpha-L-arabinofuranosidase, len: 501 aa; almost identical to SW:ABFA_STRLI (EMBL:U04630) Streptomyces lividans alpha-L-arabinofuranosidase (EC 3.2.1.55) AbfA, 662 aa. (501 aa)
SCO2432SCC24.03c, possible sugar transporter membrane protein, len: 287 aa; similar to TR:CAB59597 (EMBL:AL132662) Streptomyces coelicolor probable sugar transport inner membrane protein SCF11.20, 299 aa; fasta scores: opt: 673 z-score: 788.9 E(): 0; 35.3% identity in 278 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (287 aa)
SCO2433SCC24.04c, possible sugar transporter membrane protein, len: 313 aa; similar to TR: CAB59596(EMBL:AL132662) Streptomyces coelicolor probable sugar transporter inner membrane protein SCF11.19, 316 aa; fasta scores: opt: 533 z-score: 637.4 E(): 4.5e-28; 36.2% identity in 304 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (313 aa)
SCO2434SCC24.05c, possible sugar transporter sugar binding protein, len: 452 aa; similar to TR:CAB59595 (EMBL:AL132662) Streptomyces coelicolor, probable sugar transporter sugar binding lipoprotein SCF11.18, 442 aa; fasta scores: opt: 274 z-score: 320.2 E(): 2.1e-10; 23.3% identity in 443 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein. Contains possible N-terminal signal peptide sequence. (452 aa)
SCO2435Conserved hypothetical protein; SCC24.06, unknown, len: 175 aa; similar to TR:Q9F1V4 (EMBL:AB041825) Streptomyces ambofaciens ORF1 (genes for calcium binding) hypothetical protein, 131 aa; fasta scores: opt: 452 Z-score: 555.1 E(): 2.8e-23; 64.655% identity in 116 aa overlap. (175 aa)
SCO2436SCC24.07, possible integral membrane protein, len: 394 aa. Contains possible hydrophobic membrane spanning regions. (394 aa)
SCO2437SCC24.08, possible integral membrane protein, len: 403 aa. Contains possible hydrophobic membrane spanning regions. (403 aa)
SCO2438SCC24.09, possible secreted protein, len: 468 aa; similar to various hypothetical proteins, e.g. TR:O86550 (EMBL:AL031350) Streptomyces coelicolor hypothetical 50.7 kD protein SC1F2.13c, 476 aa; fasta scores: opt: 931 z-score: 995.7 E(): 0; 43.2% identity in 458 aa overlap. Contains possible N-terminal region signal peptide sequence. (468 aa)
SCO2750SCC57A.21c, hypothetical protein, len: 287 aa; similar to TR:CAC41509 (EMBL:AL591782) Rhizobium meliloti (Sinorhizobium meliloti) conserved hypothetical protein SMC04130, 274 aa; fasta scores: opt: 796 Z-score: 889.6 E(): 6.4e-42; 47.191% identity in 267 aa overlap. (287 aa)
SCO2751Conserved hypothetical protein SCC57A.22c; SCC57A.22c, unknown, len: 388 aa. (388 aa)
SCO2752SCC57A.23c, possible oxidoreductase, len: 378 aa. Weakly similar to several other putative oxidoreductases e.g. Streptomyces coelicolor TR:O69945 (EMBL:AL023862) putative oxidoreductase (430 aa), fasta scores opt: 252 z-score: 300.4 E(): 2.4e-09 28.8% identity in 278 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (378 aa)
SCO2753SCC57A.24, possible LacI-family transcriptional regulator, len: 348 aa. Similar to many other putative Streptomyces coelicolor LacI-family regulators including: TR:Q9X862 (EMBL:AL049661) SCE134.07 (353 aa), fasta scores opt: 489 z-score: 554.3 E(): 1.8e-23 33.8% identity in 358 aa overlap and TR:O86795 (EMBL:AL031317) SC6G4.32 (355 aa), fasta scores opt: 460 z-score: 521.7 E(): 1.2e-21 37.1% identity in 353 aa overlap. Contains a Prosite hit to PS00356 Bacterial regulatory proteins, lacI family signature and Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI fami [...] (348 aa)
SCO2754Hypothetical protein SCC57A.25; SCC57A.25, unknown, len: 268 aa. Weakly similar to Streptomyces coelicolor TR:Q9Z596(EMBL:AL035478) putative oxidoreductase (279 aa), fasta scores opt: 185 z-score: 212.6 E(): 0.00019 29.6% identity in 247 aa overlap. (268 aa)
SCO27952SCC13.03, probable sugar binding secreted protein, len: 441 aa; highly similar to TR:Q9X9R7 (EMBL:AJ009797) Streptomyces reticuli Cbp protein precursor (fragment) CebE, 444 aa; fasta scores: opt: 1490 z-score: 1672.5 E(): 0; 51.2% identity in 445 aa overlap and similar to SW:LACE_AGRRD (EMBL:X66596) Agrobacterium radiobacter Lactose-binding protein precursor LacE, 422 aa; fasta scores: opt: 263 z-score: 298.4 E(): 4.1e-09; 23.1% identity in 398 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and correctly situated match [...] (441 aa)
SCO27962SCC13.04, probable cellobiose transport permease, len: 337 aa; highly similar to TR:Q9X9R6 (EMBL:AJ009797) Streptomyces reticuli permease CebF protein, 305 aa; fasta scores: opt: 1416 z-score: 1722.4 E(): 0; 67.9% identity in 296 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible hydrophobic membrane spanning regions. (337 aa)
SCO27972SCC13.05, probable cellobiose transport permease, len: 303 aa; highly similar to TR:Q9X9R5 (EMBL:AJ009797) Streptomyces reticuli permease CebG protein, 275 aa; fasta scores: opt: 1262 z-score: 1477.0 E(): 0; 67.8% identity in 276 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible hydrophobic membrane spanning regions. (303 aa)
SCO2944SCE59.03c, possible sugar transporter membrane protein, len: 281 aa; similar to TR:CAB59590 (EMBL:AL132662) Streptomyces coelicolor putative sugar transporter inner membrane protein SCF11.13, 285 aa; fasta scores: opt: 730 z-score: 883.7 E(): 0; 42.1% identity in 278 aa overlap and to TR:AAF11008 (EMBL:AE001988) Deinococcus radiodurans ABC transporter, permease protein, MalFG family DR1436, 283 aa; fasta scores: opt: 645 z-score: 781.7 E(): 0; 38.2% identity in 272 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane co [...] (281 aa)
SCO2945SCE59.04c, possible sugar transporter membrane protein, len: 316 aa; similar to TR:CAB59589 (EMBL:AL132662) Streptomyces coelicolor putative sugar transporter inner membrane protein SCF11.12, 302 aa; fasta scores: and to TR:CAB55533 (EMBL:AL117322) Streptomyces coelicolor putative binding-protein-dependent transport protein SCF1.13, 317 aa; fasta scores: opt: 527 z-score: 611.6 E(): 1.2e-26; 33.1% identity in 302 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains also possible hydrophobic membrane [...] (316 aa)
SCO2946SCE59.05c, possible sugar transporter sugar-binding protein, len: 432 aa; similar to TR:CAB59588 (EMBL:AL132662) Streptomyces coelicolor putative sugar transporter sugar-binding protein SCF11.11, 422 aa; fasta scores: opt: 538 z-score: 581.0 E(): 6e-25; 27.0% identity in 429 aa overlap and to SW:MALX_STRPN (EMBL:L08611) Streptococcus pneumoniae maltose/maltodextrin-binding protein precursor MalX, 423 aa; fasta scores: opt: 299 z-score: 325.5 E(): 1e-10; 26.0% identity in 431 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein [...] (432 aa)
SCO3482SCE65.18c, possible sugar-permease, len: 293 aa; similar to TR:P72399 (EMBL:Y07706) Streptomyces coelicolor putative maltose permease MalG, 302 aa; fasta scores: opt: 491 z-score: 561.6 E(): 6.6e-24; 28.2% identity in 301 aa overlap. Contains match to Pfam entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains possible N-terminal region signal peptide sequence. (293 aa)
SCO3483SCE65.19c, probable integral membrane transport protein, len: 315 aa; similar to TR:O50452 (EMBL:AL021006) Mycobacterium tuberculosis probable sugar transport protein MTV006.08, 307 aa; fasta scores: opt: 542 z-score: 668.9 E(): 7e-30; 32.6% identity in 288 aa overlap. Contains match to Pfam entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and possible N-terminal region signal peptide sequence. (315 aa)
SCO3484SCE65.20c, possible secreted sugar-binding protein, len: 436 aa; similar to TR:P72397 (EMBL:Y07706) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa; fasta scores: opt: 361 z-score: 398.4 E(): 8.1e-15; 26.2% identity in 409 aa overlapand to TR:O87856 (EMBL:AL031013) Streptomyces coelicolor putative secreted sugar binding protein SC8A6.22, 438 aa; fasta scores: opt: 344 z-score: 379.6 E(): 9e-14; 23.6% identity in 365 aa overlap. Contains match to Pfam entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and match to Prosite entry correctly [...] (436 aa)
SCO3503SCE134.04c, possible binding protein dependent transport protein, len: 279aa; similar to many egs. SW:YURM_BACSU hypothetical ABC transporter permease from Bacillus subtilis (300 aa) fasta scores; opt: 424, z-score: 513.6, E(): 2.7e-21, (32.4% identity in 281 aa overlap) and SW:UGPE_ECOLI Sn-glycerol-3-phosphate transport permease from Escherichia coli (281 aa) fasta scores; opt: 350, z-score: 425.7, E(): 2.1e-16, (29.6% identity in 284 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. (279 aa)
SCO3504SCE134.05c, possible binding protein dependent transport protein, len: 327aa; similar to many egs. SW:YURN_BACSU hypothetical ABC transporter permease from Bacillus subtilis (292 aa) fasta scores; opt: 586, z-score: 707.9, E(): 4.1e-32, (32.4% identity in 287 aa overlap) and SW:UGPA_ECOLI Sn-glycerol-3-phosphate transport permease from Escherichia coli (295 aa) fasta scores; opt: 583, z-score: 704.3, E(): 6.5e-32, (33.8% identity in 290 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to [...] (327 aa)
SCO3505SCE134.06c, possible secreted substrate binding protein, len: 429aa; weak similarity to many egs. TR:O87856 (EMBL:AL031013) putative secreted sugar binding protein from Streptomyces coelicolor (438 aa) fasta scores; opt: 368, z-score: 408.8, E(): 1.9e-15, (26.2% identity in 428 aa overlap) and SW:MALE_ECOLI maltose-binding protein from Escherichia coli (396 aa) fasta scores; opt: 188, z-score: 211.5, E(): 0.00018, (23.0% identity in 374 aa overlap). Contains probable N-terminal signal sequence and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (429 aa)
SCO4240ABC transporter ATP-binding protein; Part of the ABC transporter complexes DasABC-MsiK and NgcEFG- MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for energy coupling to the transport system. (378 aa)
SCO5232Putative sugar transporter sugar binding protein; Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Binds specifically to (GlcNAc)2. Can also bind to GlcNAc, (GlcNAc)3, (GlcNAc)4 and (GlcNAc)5, but it exhibits the highest affinity for (GlcNAc)2. Involved in the control of morphological differentiation. (425 aa)
SCO5233Putative sugar transporter integral membrane protein; Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. (328 aa)
SCO5234Putative sugar transporter integral membrane protein; Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. (276 aa)
SCO5427Hypothetical protein SC6A11.03c; SC6A11.03c, unknown, len: 237 aa; no significant database similarities. (237 aa)
SCO5428SC6A11.04c, possible integral membrane transport protein, len: 296aa; similar to many proposed transport proteins e.g. TR:Q9X9Y6(EMBL:AL096743) putative integral membrane transport protein from Streptomyces coelicolor (298 aa) fasta scores: opt: 515, z-score: 609.9, E(): 1.5e-26, 33.9% identity in 295 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite matches to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible membrane-spanning hydrophobic regions. (296 aa)
SCO5429SC6A11.05c, possible integral membrane transport protein, len: 313 aa; similar to many proposed transport proteins e.g. TRNEW:CAB55533(EMBL:AL117322) putative integral membrane transport protein from Streptomyces coelicolor (317 aa) fasta scores; opt: 561, z-score: 649.2, E(): 9.4e-29, 34.4% identity in 314 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible membrane-spanning hydrophobic regions. (313 aa)
SCO5430SC6A11.06c, possible extracellular solute-binding lipoprotein, len: 458 aa; similar to many proposed solute-binding proteins e.g. TR:P72397 (EMBL:Y07706) putative maltose-binding protein from Streptomyces coelicolor (423 aa) fasta scores; opt: 284, z-score: 316.1, E(): 3.4e-10, 29.1% identity in 443 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein, Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site and possible N-terminal signal sequence. (458 aa)
SCO6004SC7B7.01c, putative secreted ATP/GTP binding protein, partial ORF, len: >626 aa; contains possible N-terminal signal sequence and PS00017 ATP/GTP-binding site motif A (P-loop); SCBAC1C11.07c, conserved hypothetical protein (fragment), len: >676 aa; similar to C-terminal domain of TR:Q9WXI8 (EMBL:AB025248) Bacillus sp. M-90 alpha-1,2-mannosidase precursor AmaN2, 1976 aa; fasta scores: opt: 1575 z-score: 1715.3 E(): 0; 45.7% identity in 705 aa overlap. (1268 aa)
SCO6005Putative lipoprotein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Binds (GlcNAc)2. Can also bind GlcNAc; Belongs to the bacterial solute-binding protein 1 family. (469 aa)
SCO6006Probable transmembrane transport protein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. (353 aa)
SCO6007Probable transmembrane transport protein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. (302 aa)
SCO6008SC7B7.05, probable transcriptional repressor protein, len 403 aa; similar to many eg. XYLR_ANATH Q44406 xylose repressor from Anaerocellum thermophilum (399 aa), fasta scores; opt: 548 z-score: 767.3 E(): 0, 33.1% identity in 393 aa overlap. Contains PS01125 ROK family signature and helix-turn-helix motif at aa positions 29-50 (Score 2016, +6.05 SD). (403 aa)
SCO6086SCBAC1A6.10, probable transport system integral membrane protein, len: 315 aa; similar to TR:P73352 (EMBL:D90905) Synechocystis sp. lactose transport system permease protein LacF, 298 aa; fasta scores: opt: 630 z-score: 734.0 E(): 0; 38.6% identity in 298 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and possible hydrophobic membrane spanning regions. (315 aa)
SCO6087SCBAC1A6.11, probable transport system integral membrane protein, len: 277 aa; similar to TR:Q9L1V0 (EMBL:AL138851) Streptomyces coelicolor putative sugar transporter inner membrane protein SCE59.03c, 281 aa; fasta scores: opt: 661 z-score: 794.5 E(): 0; 42.2% identity in 268 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and possible hydrophobic membrane spanning regions. (277 aa)
SCO6088SCBAC1A6.12, possible solute-binding transport protein, len: 430 aa; similar to TR:Q9PAP7 (EMBL:AE004053) Xylella fastidiosa ABC transporter sugar-binding protein XF2448, 430 aa; fasta scores: opt: 351 z-score: 392.9 E(): 2.6e-14; 26.2% identity in 428 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and properly situated match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains possible N-terminal region signal peptide sequence. (430 aa)
SCO6089SCBAC1A6.13, antibiotic resistance rRNA adenine methyltransferase, len: 260 aa; identical to TR:Q54386 (EMBL:M74717) Streptomyces lividans lincomycin resistance methylase Lrm, 260 aa and similar to many other macrolide antibiotic resistance proteins, e.g. SW:ERMS_STRFR (EMBL:M19269) Streptomyces fradiae rRNA adenine N-6-methyltransferase (EC 2.1.1.48) ErmSF, 319 aa; fasta scores: opt: 1003 z-score: 1217.4 E(): 0; 64.2% identity in 257 aa overlap. Contains Pfam match to entry PF00398 RrnaAD, Ribosomal RNA adenine dimethylase and match to Prosite entry PS01131 Ribosomal RNA adenine dimet [...] (260 aa)
SCO6090SCBAC1A6.14, antibiotic resistance macrolide glycosyltransferase, len: 418 aa; identical to SW:MGT_STRLI (EMBL:M74717) Streptomyces lividans macrolide glycosyltransferase (EC 2.4.1.*) Mgt, 418 aa. Contains Pfam match to entry PF00201 UDPGT, UDP-glucoronosyl and UDP-glucosyl transferases and match to Prosite entry PS00375 UDP-glycosyltransferases signature; Belongs to the UDP-glycosyltransferase family. (418 aa)
SCO6229SC2H4.11c, probable sugar transport system permease protein, len: 293 aa; similar to many e.g. MALD_STRPN maltodextrin transport system permease protein (277 aa), fasta scores; opt: 394 z-score: 585.4 E(): 2.3e-25, 29.1% identity in 268 aa overlap. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp signature. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, score 58.30, E-value 1.6e-13. (293 aa)
SCO6230SC2H4.12c, probable sugar transport system permease protein, len: 324 aa; similar to many e.g. AMYD_THETU potential starch degradation products transport system permease (292 aa), fasta scores; opt: 479 z-score: 571.8 E(): 1.3e-24, 28.8% identity in 281 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, score 58.80, E-value 1.2e-13. (324 aa)
SCO6231SC2H4.13c, probable sugar transport system sugar-binding lipoprotein, len: 440 aa; some similarity to several, e.g. TR:Q46443 (EMBL:M57692) Thermoanaerobacterium thermosulfurigenes maltose-binding protein precursor (446 aa), fasta scores; opt: 239 z-score: 192.4 E(): 0.0018, 23.5% identity in 366 aa overlap. Contains N-terminal signal sequence with appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site sugar transport system sugar-binding lipoprotein. (440 aa)
SCO6232SC2H4.14, probable beta-mannosidase, len: 820 aa; similar to several eukaryotic beta-mannosidases, e.g. MANB_HUMAN beta-mannosidase precursor (EC 3.2.1.25) (879 aa), fasta scores; opt: 679 z-score: 909.3 E(): 0, 31.4% identity in 684 aa overlap. (820 aa)
SCO6233SC2H4.15, probable transcriptional regulator, len: 342 aa; similar to many members of the lacI family e.g. CCPA_BACME glucose-resistance amylase regulator (Bacillus megaterium) (332 aa), fasta scores; opt: 448 z-score: 548.6 E(): 2.6e-23, 29.8% identity in 336 aa overlap. Contains helix-turn-helix motif from aa 9-30 (Score 1778, +5.24 SD) and Pfam matches to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, score 30.40, E-value 4.7e-07 and to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, score 44.00, E-value 3.4e-09. (342 aa)
SCO6600SC8A6.21c, probable transcriptional regulator, len: 441 aa; some similarity to members of the ROK family e.g. XYLR_ANATH xylose repressor (399 aa), fasta scores; opt: 365 z-score: 361.7 E(): 6.6e-13, 27.2% identity in 397 aa over lap. Contains Pfam match to entry PF00480 ROK, ROK family, score 38.10, E-value 3e-10. (441 aa)
SCO6601SC8A6.22, probable secreted sugar binding protein, l en: 438 aa; similar to e.g. S. coelicolor TR:P72397 (EMBL:Y 07706) putative maltose-binding pootein malE (423 aa), fast a scores; opt: 425 z-score: 307.7 E(): 6.7e-10, 28.9% ident ity in 439 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane l ipoprotein lipid attachment site. (438 aa)
SCO6602SC8A6.23, probable transmembrane sugar transport pro tein, len: 342 aa; similar to e.g. S. coelicolor TR:P72398 (EMBL:Y07706) putative maltose permease malF (334 aa), fast a scores; opt: 494 z-score: 521.6 E(): 8.2e-22, 32.6% ident ity in 322 aa overlap. Contains PS00017 ATP/GTP-binding sit e motif A (P-loop), PS00402 Binding-protein-dependent trans port systems inner membrane comp signature and Pfam match t o entry PF00528 BPD_transp, Binding-protein-dependent trans port systems inner membrane component, score 42.00, E-value 1.3e-08. (342 aa)
SCO6603SC8A6.24, probable transmembrane sugar transport pro tein, len: 279 aa; similar to e.g. S. coelicolor TR:P72399 (EMBL:Y07706) putative maltose permease malG (302 aa), fast a scores; opt: 542 z-score: 755.1 E(): 0, 36.7% identity in 270 aa overlap. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp signature and Pfam m atch to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, score 75.20, E -value 1.3e-18. (279 aa)
SCO7011SC8F11.37c, possible membrane transport protein, len: 291 aa. Identical to Streptomyces lividans TR:O86873(EMBL:U22894) integral membrane protein, AglG (291 aa), fasta scores opt: 1890 z-score: 2239.5 E():0 100.0% identity in 291 aa overlap. Also similar to many putative sugar transport proteins e.g. Clostridium perfringens TR:Q06111(EMBL:X66092) putative transport system permease protein (275 aa), fasta scores opt: 515 z-score: 616.2 E(): 6.9e-27 32.4% identity in 259 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membr [...] (291 aa)
SCO7012SC1H10.01c, possible binding protein dependent transport protein, partial CDS, len: > 288 aa. Almost identical to Streptomyces lividans TR:O86872(EMBL:U22894) integral membrane protein, AglF (231 aa), fasta scores opt: 1469 z-score: 1755.6 E(): 0 96.9% identity in 224 aa overlap. Also similar to Streptomyces coelicolor TR:CAB59596(EMBL:AL132662) probable sugar transporter inner membrane protein, SCF11.19 (316 aa), fasta scores opt: 575 z-score: 690.1 E(): 5.1e-31 38.1% identity in 273 aa overlap. Contains a Prosite hit to PS00402 Binding-protein-dependent transport systems inner membra [...] (319 aa)
SCO7013Putative sugar-binding lipoprotein; SC1H10.02C, possible sugar-binding lipoprotein, len: 471 aa. Identical to Streptomyces lividans TR:Q54334(EMBL:U22894) sugar binding lipoprotein precursor, AlgE (471 aa), fasta scores opt: 3154 z-score: 3469.8 E():0 100.0% identity in 471 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prosite hit to PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (471 aa)
SCO7014SC1H10.03c, probable LacI-family transcriptional regulatory protein, len: 337 aa. Identical to Streptomyces lividans protein encoded on the 1 kb TR:Q57276 (EMBL:X65466) right direct repeat sequence contained within the amplifiable AUD1 element (337 aa), fasta scores opt: 2188 z-score: 2534.7 E():0 99.7% identity in 337 aa overlap. Also highly similar to Streptomyces coelicolor SW:MALR_STRCO (EMBL:Y07706) maltose operon transcriptional repressor, MalR or SC10B7.03c (344 aa), fasta scores opt: 1114 z-score: 1293.5 E():0 53.3% identity in 336 aa overlap. This gene is duplicated on this co [...] (337 aa)
SCO7015SC1H10.04c, possible secreted glycosyl hydrolase, len: 1433 aa. Identical to Streptomyces lividans TR:P75020(EMBL:U22894) chitinase homolog found within the 4.7 kb amplifiable unit of the AUD1 element (1433 aa), fasta scores opt: 9322 z-score: 9526.2 E():0 99.5% identity in 1433 aa overlap. C-terminal similar to TR:BAB62749 (EMBL:AB055506) mycodextranase from Streptomyces sp. J-13-3 fasta scores; opt: 865, Z-score: 887.6, 32.953% identity (36.861% ungapped) in 613 aa overlap. Also weakly similar, in parts, to Bacillus circulans SW:CHI1_BACCI(EMBL:M57601) chitinase A1 precursor (EC 3.2. [...] (1433 aa)
SCO7016SC1H10.05c, possible LacI-family transcriptional regulatory protein, len: 336 aa. Identical to Streptomyces lividans protein encoded on the 1 kb TR: Q57094(EMBL:U22894) left direct repeat sequence contained within the amplifiable AUD1 element (336 aa), fasta scores opt: 2173 z-score: 2549.4 E():0 99.4% identity in 336 aa overlap. Also highly similar to Streptomyces coelicolor SW:MALR_STRCO (EMBL:Y07706) maltose operon transcriptional repressor, MalR or SC10B7.03c (344 aa), fasta scores opt: 1137 z-score: 1336.5 E():0 53.7% identity in 341 aa overlap. This gene is duplicated on this cos [...] (336 aa)
SCO7017SC1H10.06c, possible membrane protein, len: 297 aa. Similar to several including: Streptomyces coelicolor TR:Q9XAL0 (EMBL:AL079348) putative membrane protein, SC66T3.03 (330 aa), fasta scores opt: 561 z-score: 634.9 E(): 6.4e-28 50.8% identity in 315 aa overlap. Contains possible membrane spanning hydrophobic domains. (301 aa)
SCO7027SC1H10.16c, probable LacI-family transcriptional regulator, len: 339 aa. Highly similar to Streptomyces lividans TR:Q9ZI18 (EMBL:AF043654) LacI-GalR family regulatory protein, BxlR (338 aa), fasta scores opt: 2136 z-score: 2395.5 E(): 0 96.5% identity in 340 aa overlap and Escherichia coli SW:CYTR_ECOLI (EMBL:X03683) transcriptional repressor, CytR (341 aa), fasta scores opt: 553 z-score: 625.0 E(): 2.2e-27 32.7% identity in 330 aa overlap. Also highly similar to Streptomyces coelicolor TR:O86795(EMBL:AL031317) putative transcriptional regulator, SC6G4.32 (355 aa), fasta scores opt: 13 [...] (339 aa)
SCO7028Putative sugar-binding lipoprotein; SC1H10.17, possible sugar-binding lipoprotein, len: 434 aa. Identical to Streptomyces lividans TR:Q9Z492 (EMBL:AF043654) putative sugar-binding protein, BxlE (434 aa), fasta scores opt: 2892 z-score: 3295.8 E():0 99.5% identity in 434 aa overlap. Also similar to Streptococcus mutans SW:MSME_STRMU(EMBL:M77351) multiple sugar-binding protein precursor, MsmE (420 aa), fasta scores opt: 308 z-score: 353.5 E(): 2.9e-12 24.0% identity in 383 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prosite hit to PS00013 Pr [...] (434 aa)
SCO7029SC1H10.18, possible binding-protein-dependent transport protein, len: 318 aa. Almost identical to Streptomyces lividans TR:Q9ZI17 (EMBL:AF043654) putative permease, BxlF (317 aa), fasta scores opt:2000 z-score: 2320.3 E():0 98.1% identity in 318 aa overlap. Also similar to Streptococcus mutans SW:MSMF_STRMU(EMBL:M77351) multiple sugar-binding transport system permease protein, MsmF (290 aa), fasta scores opt: 447 z-score: 524.7 E(): 8.3e-22 29.9% identity in 271 aa overlap and Streptomyces coelicolor TR:CAB54176(EMBL:AL110470) putative binding-protein-dependent transport protein, SCF85 [...] (318 aa)
SCO7030SC1H10.19, possible binding-protein-dependent transport protein, len: 310 aa. Almost identical to Streptomyces lividans TR:Q9ZI16 (EMBL:AF043654) putative permease, BxlG (272 aa), fasta scores opt: 1714 z-score: 2067.9 E():0 98.5% identity in 272 aa overlap. Also similar to Streptococcus mutans SW:MSMG_STRMU(EMBL:M77351) multiple sugar-binding transport system permease protein, MsmG (277 aa), fasta scores opt: 441 z-score: 537.9 E(): 1.5e-22 28.0% identity in 254 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane co [...] (272 aa)
SCO7031beta-D-xylosidase; SC1H10.20, beta-D-xylosidase, len: 797 aa. Highly similar to Streptomyces lividans TR:Q9ZI15 (EMBL:AF043654) beta-D-xylosidase, BxlA (861 aa), fasta scores opt: 4473 z-score: 4774.4 E(): 0 89.2% identity in 789 aa overlap. Also highly similar to Streptomyces coelicolor TR:CAB55650(EMBL:AL117385) putative beta-xylosidase, SC5G9.02 (796 aa), fasta scores opt: 4215 z-score: 4499.4 E(): 0 79.1% identity in 788 aa overlap. Contains a Pfam matches to entries PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain and Pfam match to entry PF01915 Glyco_hydro_3_C [...] (797 aa)
SCO7165SC9A4.27c, probable sugar-binding integral membrane transport protein, len: 319 aa; similar to TR:Q9RJV6 (EMBL:AL117387) Streptomyces coelicolor putative binding-protein-dependent transport protein SCF41.13, 280 aa; fasta scores: opt: 1039 z-score: 1201.7 E(): 0; 57.2% identity in 264 aa overlap and to SW:MSMG_STRMU (EMBL:M77351) Streptococcus mutans multiple sugar-binding transport system permease protein MsmG, 277 aa; fasta scores: opt: 512 z-score: 596.7 E(): 9.1e-26; 32.4% identity in 275 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transpo [...] (303 aa)
SCO7166SC9A4.28c, probable sugar-transporter integral membrane protein, len: 310 aa; similar to TR:Q9RJV7 (EMBL:AL117387) Streptomyces coelicolor putative binding protein dependent transport protein SCF41.12, 303 aa; fasta scores: opt: 913 z-score: 1073.6 E(): 0; 46.9% identity in 309 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible hydrophobic membrane spanning regions. (310 aa)
SCO7405Putative acetyltransferase (fragment); SC6D11.01c, possible acetyltransferase, partial CDS, len: > 72 aa. Similar to the N-terminus of Escherichia coli SW:THGA_ECOLI(EMBL:J01636) galactoside O-acetyltransferase (EC 2.3.1.18) (203 aa), fasta scores opt: 138 z-score: 187.9 E(): 0.0048 38.3% identity in 60 aa overlap. Overlaps and extends into CDS SC10G8.33c on the adjoining cosmid.; SC10G8.33c, possible acetyltransferase, partial CDS, len: > 175 aa. Highly similar to a number of acetyltransferases e.g. Escherichia coli SW:THGA_ECOLI(EMBL:J01636) galactoside o-acetyltransferase (EC 2.3.1. [...] (215 aa)
SCO7406Putative secreted protein; SC6D11.02C, possible secreted protein, len: 691 aa. Contains a 8xGT repeat region within the C-terminus and a possible N-terminal signal sequence. (691 aa)
SCO7408SC6D11.04c, probable solute-binding lipoprotein, len: 451 aa. Similar to several other transport proteins including: Agrobacterium radiobacter SW:LACE_AGRRD(EMBL:X66596) lactose-binding protein precursor, LacE (422 aa), fasta scores opt: 347 z-score: 393.9 E(): 1.6e-14 24.0% identity in 425 aa overlap and Streptomyces coelicolor TR:CAB61177(EMBL:AL132973) probable solute-binding lipoprotein, SCF91.20 (443 aa), fasta scores opt: 550 z-score: 621.9 E(): 3.2e-27 26.2% identity in 455 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prosite hit to [...] (451 aa)
SCO7409SC6D11.05c, possible binding-protein dependent transport protein, len: 316 aa. Similar to many including: Streptomyces coelicolor TR:CAB61179(EMBL:AL132973) putative binding protein dependent transport protein, SCF91.22 (287 aa), fasta scores opt: 875 z-score: 1002.5 E(): 0 45.9% identity in 281 aa overlap. Contains possible membrane spanning hydrophobic domains and a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. (316 aa)
SCO7410SC6D11.06c, possible binding-protein dependent transport protein, len: 308 aa. Similar to many other transport proteins e.g. Streptomyces coelicolor TR:CAB61178(EMBL:AL132973) putative binding protein dependent transport protein, SCF91.21 (328 aa), fasta scores opt: 622 z-score: 709.6 E(): 4.2e-32 35.9% identity in 315 aa overlap. Contains possible membrane spanning hydrophobic domains and a Prosite hit to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inne [...] (308 aa)
SCO7411SC6D11.07, possible LacI-family transcriptional regulator, len: 352 aa. Similar to several including Escherichia coli SW:LACI_ECOLI (EMBL:V00294) lactose operon repressor LacI (360 aa), fasta scores opt: 595 z-score: 670.0 E(): 6.7e-30 34.8% identity in 333 aa overlap and Streptomyces coelicolor TR:O86618 (EMBL:AL031155) putative transcriptional regulator SC3A7.17 (361 aa), fasta scores opt: 887 z-score: 995.3 E(): 0 46.0% identity in 350 aa overlap. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family and PF00532 Peripla_BP_like, Periplasmic bindin [...] (352 aa)
SCO7484Hypothetical protein; SCBAC17A6.17c, unknown, len: 78 aa: no significant database matches. (78 aa)
SCO7485SCBAC17A6.18c, possible oxidoreductase, len: 228aa; similar to many eg. TR:Q9L2J5 (EMBL:AL137165) putative oxidoreductase SCF42.24 from Streptomyces coelicolor (295 aa) fasta scores; opt: 450, Z-score: 508.6, 43.850% identity (45.304% ungapped) in 187 aa overlap and TR:BAB49857 (EMBL:AP003000) probable oxidoreductase from Rhizobium loti (319 aa) fasta scores; opt: 243, Z-score: 278.7, 31.980% identity (35.795% ungapped) in 197 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. (228 aa)
SCO7486SCBAC17A6.19c, possible ROK-family transcriptional regulator, len: 405 aa; similar to many e.g. TR:P95610 (EMBL:X99622) putative regulator from Rhodococcus erythropolis (397 aa) fasta scores: opt: 548, Z-score: 588.4, 36.776% identity (38.220% ungapped) in 397 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and Prosite match to PS01125 ROK family signature. (405 aa)
SCO7487SCBAC17A6.20c, possible integral membrane binding protein dependent transport protein, len: 294aa; similar to many eg. TR:BAB49483 (EMBL:AP002999) permease protein of sugar ABC transporter from Rhizobium loti (296 aa) fasta scores: opt: 608, Z-score: 696.1, 35.570% identity (36.934% ungapped) in 298 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane spanning regions. (294 aa)
SCO7488SCBAC17A6.21c, possible integral membrane binding protein dependent transport protein, len: 343aa; similar to many eg. SW:Q04698 (MALC_STRPN) maltodextrin transport permease from Streptococcus pneumoniae (435 aa) fasta scores: opt: 376, Z-score: 423.7, 26.959% identity (29.153% ungapped) in 319 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to S00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane spanning regions. (343 aa)
SCO7489SCBAC17A6.22c, possible binding protein dependent transport lipoprotein, len: 467aa; weakly similar to many eg. SW:P76042 (YCJN_ECOLI) putative ABC transporter from Escherichia coli (430 aa) fasta scores: opt: 346, Z-score: 385.6, 26.009% identity (29.668% ungapped) in 446 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (467 aa)
SCO7490SCBAC17A6.23, possible oxidoreductase, len: 381aa; similar to many eg. TR:Q9F1Z9 (EMBL:AB033991) BtrE from Bacillus circulans (349 aa) fasta scores: opt: 710, Z-score: 676.3, 38.873% identity (41.071% ungapped) in 355 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. N-terminus rich in pro/val/ser. (381 aa)
SCO7491SCBAC17A6.24, conserved hypothetical protein, len: 266aa; similar to many eg. SW:P76044 (YCJR_ECOLI) hypothetical protein from Escherichia coli (265 aa) fasta scores: opt: 571, Z-score: 667.8, 36.502% identity (37.209% ungapped) in 263 aa overlap. (266 aa)
SCO7492Hypothetical protein; SCBAC17A6.25, unknown, len: 454 aa; no significant database matches. (454 aa)
SCO7493SCBAC17A6.26, conserved hypothetical protein, len: 645 aa; similar to many e.g. TR:Q9K6N7 (EMBL:AP001519) BH3691 protein from Bacillus halodurans (702 aa) fasta scores: opt: 1188, Z-score: 1277.9, 34.802% identity (37.175% ungapped) in 658 aa overlap. (645 aa)
SCO7502SCBAC17A6.35c, possible LacI-family transcriptional regulator, len: 346 aa; similar to many e.g. SW:P46828 (CCPA_BACME) glucose-resistance amylase regulator CcpA from Bacillus megaterium (332 aa) fasta scores: opt: 528, Z-score: 565.6, 30.769% identity (31.902% ungapped) in 338 aa overlap and TR:Q9K433 (EMBL:AL359779) putative LacI-family transcriptional regulator from Streptomyces coelicolor (340 aa) fasta scores: opt: 993, Z-score: 1055.5, 49.422% identity (51.506% ungapped) in 346 aa overlap. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and suga [...] (346 aa)
SCO7503SCBAC17A6.36, putative extracellular solute-binding protein, len: 445aa; similar to many eg. TR:Q9L0B2 (EMBL:AL163003) putative sugar transporter sugar binding protein from Streptomyces coelicolor (452 aa) fasta scores: opt: 853, Z-score: 952.9, 37.275% identity (38.259% ungapped) in 389 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and a possible N-terminal signal sequence. (445 aa)
SCO7504SCBAC17A6.37, possible integral membrane binding-protein-dependent transport protein, len: 316aa; similar to many eg. TR:Q9L0B3 (EMBL:AL163003) putative sugar transporter integral membrane protein from Streptomyces coelicolor (313 aa) fasta scores: opt: 949, Z-score: 1058.2, 48.867% identity (50.671% ungapped) in 309 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component; Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane span [...] (316 aa)
SCO7505SCBAC17A6.38, possible integral membrane binding-protein-dependent transport protein, len: 299aa; similar to many eg. TR:Q9L0B4 (EMBL:AL163003) putative sugar transporter integral membrane protein from Streptomyces coelicolor (313 aa) fasta scores: opt: 905, Z-score: 1049.4, 50.000% identity (51.799% ungapped) in 288 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component; Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane span [...] (299 aa)
SCO7555SC5F1.09, possible solute binding lipoprotein, len: 436 aa; similar to TR:Q9L151 (EMBL:AL158061) Streptomyces coelicolor probable solute binding lipoprotein SC6D11.04c, 451 aa; fasta scores: opt: 386 z-score: 436.1 E(): 9.3e-17; 27.5% identity in 459 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and correctly situated match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains possible N-terminal signal peptide sequence. (436 aa)
SCO7556SC5F1.10, possible sugar transport permease, len: 331 aa; similar to TR:Q9X9R6 (EMBL:AJ009797) Streptomyces reticuli CebF protein, 305 aa; fasta scores: opt: 1258 z-score: 1401.2 E(): 0; 57.6% identity in 311 aa overlap and to TR:CAC10105 (EMBL:AL442165) Streptomyces coelicolor putative cellobiose transport permease 2SCC13.04, 337 aa; fasta scores: opt: 1343 z-score: 1424.3 E(): 0; 56.5% identity in 336 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-depe [...] (331 aa)
SCO7557SC5F1.11, possible sugar transport integral membrane protein, len: 307 aa; similar to TR:Q9X9R5 (EMBL:AJ009797) Streptomyces reticuli CebG protein, 275 aa; fasta scores: opt: 1165 z-score: 1331.6 E(): 0; 62.8% identity in 274 aa overlap and to TR:CAC10106 (EMBL:AL442165) Streptomyces coelicolor putative cellobiose transport permease 2SCC13.05, 303 aa; fasta scores: opt: 1236 z-score: 1261.9 E(): 0; 61.1% identity in 296 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Also contains possible hydrophobic me [...] (307 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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