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SCO0213 SCO0213 SCO0216 SCO0216 SCO0217 SCO0217 SCO0218 SCO0218 SCO0219 SCO0219 SCO2473 SCO2473 SCO2486 SCO2486 SCO2487 SCO2487 SCO2488 SCO2488 SCO2553 SCO2553 SCO2959 SCO2959 SCO4947 SCO4947 SCO4948 SCO4948 SCO4949 SCO4949 SCO4950 SCO4950 SCO6532 SCO6532 SCO6533 SCO6533 SCO6534 SCO6534 SCO6535 SCO6535
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO0213SCJ12.25c, possible nitrate/nitrite transporter protein, len: 412 aa. Similar to Bacillus subtilis SW:NARK_BACSU (EMBL; Z49884) nitrite extrusion protein (395 aa), fasta scores opt: 834 z-score: 877.9 E():0 36.8% identity in 378 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. (412 aa)
SCO0216SCJ12.28, narG2, probable nitrate reductase alpha chain, len: 1233 aa. Highly similar to Streptomyces coelicolor TR:O86717 (EMBL; AL031515) putative nitrate reductase alpha chain NarG SC5C7.20c (1231 aa), fasta scores: opt: 5792 z-score: 6544.7 E(): 0 67.6% identity in 1230 aa overlap and Bacillus subtilis SW:NARG_BACSU (EMBL; Z49884) nitrate reductase alpha chain (EC 1.7.99.4) NarG (1228 aa), fasta scores: opt: 4331 z-score: 4891.8 E(): 0 52.9% identity in 1201 aa overlap. Contains a PS00551 Prokaryotic molybdopterin oxidoreductases signature 1, a Pfam match to entry PF00384 molybdopt [...] (1233 aa)
SCO0217SCJ12.29, narH2, probable nitrate reductase beta chain, len: 522 aa. Highly similar to many e.g. Streptomyces coelicolor TR:O86716 (EMBL; AL031515) putative nitrate reductase beta chain NarH SC5C7.19c (531 aa), fasta scores: opt: 2348 z-score: 2413.0 E(): opt: 2348 z-score: 2413.0 E(): 0 65.3% identity in 496 aa overlap and Bacillus subtilis SW:NARH_BACSU (EMBL; Z49884) nitrate reductase beta chain (EC 1.7.99.4) NarH (487 aa), fasta scores: opt: 2081 z-score: 2139.7 E(): 0 57.1% identity in 485 aa overlap. Contains a PS00190 Cytochrome c family heme-binding site signature, a Pfam match [...] (522 aa)
SCO0218SCJ12.30, narJ2, probable nitrate reductase delta chain, len: 267 aa. Similar to many e.g. Bacillus subtilis SW:NARJ_BACSU (EMBL:Z49884) nitrate reductase delta chain NarJ (EC 1.7.99.4) SC5C7.18c (184 aa), fasta scores: opt: 287 z-score: 314.9 E(): 3.5e-10 32.9% identity in 164 aa overlap and Streptomyces coelicolor TR:O86715 (EMBL:AL031515) nitrate reductase delta chain SC5C7.18c (164 aa), fasta scores: opt: 309 z-score: 338.8 E(): 1.6e-11 40.1% identity in 172 aa overlap. (267 aa)
SCO0219SCJ12.31, narI2, possible nitrate reductase gamma chain, len: 256 aa. Similar to many including: Streptomyces coelicolor TR:O86714 (EMBL:AL031515) putative nitrate reductase gamma chain NarI SC5C7.17c (240 aa), fasta scores: opt: 755 z-score: 891.5 E(): 0 46.8% identity in 235 aa overlap and Bacillus subtilis SW:NARI_BACSU (EMBL:Z49884) nitrate reductase gamma chain (EC 1.7.99.4) (223 aa), fasta scores: opt: 668 z-score: 790.4 E(): 0 43.6% identity in 225 aa overlap. Contains possible membrane spanning hydrophobic domains. (256 aa)
SCO2473SC7A8.12, probable nitrate reductase, len: 819 aa; similar to SW:NASC_BACSU (EMBL:D50453) Bacillus subtilis assimilatory nitrate reductase catalytic subunit (EC 1.7.99.4) NasC, 710 aa; fasta scores: opt: 1568 z-score: 1572.1 E(): 0; 37.9% identity in 816 aa overlap. Contains Pfam matches to entries PF00384 molybdopterin, Prokaryotic molybdopterin oxidoreductases and PF01568 Molydop_binding, Molydopterin dinucleotide binding domain. Contains also glycine/serine rich region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (819 aa)
SCO2486SC7A8.25, nirB, probable nitrite reductase, len: 410 aa; similar to N-terminal region of TR:O53674 (EMBL:AL021929) Mycobacterium tuberculosis nitrite reductase large subunit NirB, 853 aa; fasta scores: opt: 657 z-score: 711.6 E(): 3e-32; 37.8% identity in 431 aa overlap and to SW:NIRB_KLEPN (EMBL:L06800) Klebsiella pneumoniae nitrite reductase [NAD(P)H] large subunit (EC 1.6.6.4) NasB, 957 aa; fasta scores: opt: 636 z-score: 688.3 E(): 6e-3; 35.4% identity in 412 aa overlap. Contains possible N-terminal region signal peptide sequence. (410 aa)
SCO2487SC7A8.26, nirB, probable nitrite reductase large subunit, len: 871 aa; similar to TR:Q00943 (EMBL:Z68122) Pichia angusta nitrite reductase Yni1, 1044 aa; fasta scores: opt: 1960 z-score: 2117.6 E(): 0; 43.2% identity in 868 aa overlap and SW:NIRB_ECOLI (EMBL:X14202) Escherichia coli nitrite reductase [NAD(P)H] large subunit (EC 1.6.6.4) NirB 847 aa; fasta scores:opt: 1609 z-score: 1739.1 E(): 0; 52.1% identity in 845 aa overlap. Contains Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase and two matches to Prosite entries PS00136 Serine proteases, subtilase family, asp [...] (871 aa)
SCO2488SC7A8.27, nirC, probable nitrite reductase small subunit, len: 131 aa; similar to TR:O53675 (EMBL:AL021929) Mycobacterium tuberculosis nitrite reductase small subunit NirD, 118 aa; fasta scores: opt: 353 z-score: 455.1 E(): 5.9e-18; 56.5% identity in 92 aa overlap and to SW:NIRD_ECOLI (EMBL:X14202) Escherichia coli nitrite reductase [NAD(P)H] small subunit (EC 1.6.6.4) NirD, 108 aa; fasta scores: opt: 265 z-score: 346.0 E(): 7e-12; 46.9% identity in 96 aa overlap. (131 aa)
SCO2553SCC77.20c, possible oxidoreductase, len: 364 aa. This CDS has been partially sequenced and the C-terminal 142 aa, of its predicted protein product, are identical to Streptomyces coelicolor TR:Q02797(EMBL:X68792) hypothetical protein in pth270 promoter (fragment). Also highly similar to Mycobacterium tuberculosis TR:O33323(EMBL:AL008967) oxidoreductase (344 aa), fasta scores opt: 912 z-score: 971.6 E(): 0 45.5% identity in 336 aa overlap and Bacillus subtilis TR:O05413(EMBL:U93875) 2-nitropropane dioxygenase (347 aa), fasta scores opt: 702 z-score:749.8 E(): 0 37.8% identity in 339 aa o [...] (364 aa)
SCO2959SCE59.18c, probable nitrate extrusion protein, len: 452 aa; similar to SW:NARK_ECOLI (EMBL:X15996) Escherichia coli nitrite extrusion protein 1 (nitrite facilitator 1) NarK, 463 aa; fasta scores: opt: 526 z-score: 590.8 E(): 1.7e-25; 39.7% identity in 451 aa overlap. Contains possible hydrophobic membrane spanning regions. (452 aa)
SCO49472SCK31.07, narG3, nitrate reductase alpha chain, len: 1227 aa; highly similar to SW:NARG_BACSU (EMBL:Z49884) Bacillus subtilis nitrate reductase alpha chain (EC 1.7.99.4)NarG, 1228 aa; fasta scores: opt: 4080 z-score: 4618.0 E(): 0; 49.5% identity in 1206 aa overlap and to TR:O86717 (EMBL:AL031515) Streptomyces coelicolor NarG, putative nitrate reductase alpha chain SC5C7.20, 1231 aa; fasta scores: opt: 5648 z-score: 5294.1 E(): 0; 66.6% identity in 1232 aa overlap. Contains Pfam matches to entries PF00384 molybdopterin, Prokaryotic molybdopterin oxidoreductases and PF01568 Molydop_bin [...] (1227 aa)
SCO49482SCK31.08, narH3, nitrate reductase beta chain, len: 548 aa; highly similar to SW:NARH_BACSU (EMBL:Z49884) Bacillus subtilis nitrate reductase beta chain NarH, 487 aa; fasta scores: opt: 2088 z-score: 2047.9 E(): 0; 58.2% identity in 483 aa overlap and to TR:O86716 (EMBL:AL031515) Streptomyces coelicolor NarH, putative nitrate reductase beta chain SC5C7.19, 531 aa; fasta scores: opt: 2542 z-score: 2343.2 E(): 0; 71.6% identity in 503 aa overlap. (548 aa)
SCO49492SCK31.09, narJ3, nitrate reductase delta chain, len: 237 aa; similar to SW:NARJ_BACSU (EMBL:Z49884) Bacillus subtilis nitrate reductase delta chain (EC 1.7.99.4) NarJ, 184 aa; fasta scores: opt: 332 z-score: 411.9 E(): 2.1e-15; 35.0% identity in 163 aa overlap and to TR:Q9RI30 (EMBL:AL109989) Streptomyces coelicolor NarJ2 SCJ12.30, 267 aa; fasta scores: opt: 436 z-score: 447.2 E(): 3.3e-19; 41.7% identity in 204 aa overlap. (220 aa)
SCO49502SCK31.10, narI3, nitrate reductase gamma chain, len: 237 aa; highly similar to SW:NARI_BACSU (EMBL:Z49884) Bacillus subtilis nitrate reductase gamma chain (EC 1.7.99.4) NarI, 223 aa; fasta scores: opt: 792 z-score: 991.9 E(): 0; 49.6% identity in 234 aa overlap and to TR:Q9RI29 (EMBL:109989) Streptomyces coelicolor putative nitrate reductase delta chain NarI2 SCJ12.31, 256 aa; fasta scores: opt: 813 z-score: 891.7 E(): 0; 54.3% identity in 230 aa overlap. Contains possible hydrophobic membrane spanning regions. (237 aa)
SCO6532SC5C7.17c, narI, probable nitrate reductase gamma chain; len: 240 aa; similar to many e.g. NARI_BACSU nitrate reductase gamma chain (EC 1.7.99.4) (223 aa), fasta scores; opt: 664 z-score: 1084.3 E(): 0, 41.5% identity in 217 aa overlap. Contains possible hydrophobic membrane spanning regions. (240 aa)
SCO6533SC5C7.18c, narJ, probable nitrate reductase delta chain, len: 164 aa; similar to many e.g. NARJ_BACSU nitrate reductase delta chain (EC 1.7.99.4) (184 aa), fasta scores; opt: 208 z-score: 429.0 E(): 1.2e-16, 30.1% identity in 163 aa overlap. (164 aa)
SCO6534SC5C7.19c, narH, probable nitrate reductase beta chain, len: 531 aa; highly similar to many e.g. NARH_BACSU nitrate reductase beta chain (EC 1.7.99.4) (487 aa), fasta scores; opt: 2099 z-score: 2179.2 E(): 0, 58.0% identity in 495 aa overlap. Contains PS00190 Cytochrome c family heme-binding site signature and Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains, score 61.10, E-value 1.8e-16. (531 aa)
SCO6535SC5C7.20c, narG, probable nitrate reductase alpha chain, len: 1231 aa; highly similar to many e.g. NARG_BACSU nitrate reductase alpha chain (EC 1.7.99.4) (1228 aa), fasta scores; opt: 4306 z-score: 3216.7 E(): 0, 51.5% identity in 1235 aa overlap. Contains PS00551 and PS00490 Prokaryotic molybdopterin oxidoreductases signatures 1 and 2 and Pfam match to entry PF00384 molybdopterin, Prokaryotic molybdopterin oxidoreductases, score 79.90, E-value 1e-24; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1231 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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