(8 nodes) Mixed, incl. DhaK domain, and Ketol-acid reductoisomerase, N-terminal network (Streptomyces coelicolor)

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Your Input:
	SCO0460	Hypothetical protein SCF51A.38; SCF51A.38, unknown, len: 169 aa. (169 aa)
	SCO0461	SCF76.01, possible hydrolase, partial CDS, len: >228 aa. Similar to several hypothetical proteins e.g. from Saccharomyces cerevisiae SW:YN93_YEAST (EMBLL:Z71679) (290 aa), fasta scores opt: 609 z-score: 749.0 E():0 42.4% identity in 229 aa overlap. Also weakly similar to Xanthobacter autotrophicus SW:HALO_XANAU (EMBL:M26950) haloalkane dehalogenase (EC 3.8.1.5) (310 aa), fasta scores opt: 151 z-score: 190.4 E():0.003 22.9% identity in 231 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold; SCF51A.39, possible hydrolase, partial CDS, len: >113 aa. [...] (289 aa)
	SCO0576	SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap. (291 aa)
	SCO0577	SCF55.01c, hypothetical protein, len: >231 aa; similar to SW:YIHM_ECOLI (EMBL:L19201) Escherichia coli hypothetical 36.9 KD protein in GlnA-Rbn intergenic region, 326 aa; fasta scores: opt: 188 z-score: 232.7 E(): 1.4e-05; 22.1% identity in 217 aa overlap; SC5G5.09c, conserved hypothetical protein (fragment), len: >92 aa; similar to C-terminal region of TR:BAB38218 (EMBL:AP002567) Escherichia coli O157:H7 hypothetical 37.1 kDa protein ECS4795, 326 aa; fasta scores: opt: 106 Z-score: 142.9 bits: 33.0 E(): 2.4; 25.882% identity in 85 aa overlap. (266 aa)
	SCO0580	SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap. (593 aa)
	SCO0581	SCF55.05c, probable transporter protein, len: 455 aa; similar to SW:TUB4_AGRVI (EMBL:U25634) Agrobacterium vitis putative tartrate transporter Tub4, 433 aa; fasta scores: opt: 894 z-score: 1016.3 E(): 0; 42.8% identity in 432 aa overlap and to SW:PHT1_PSEPU (EMBL:D13229) Pseudomonas putida phthalate transporter Pht1, 451 aa; fasta scores: opt: 745 z-score: 847.5 E(): 0; 30.8% identity in 435 aa overlap. Contains match to Pfam entry PF00083 sugar_tr, Sugar (and other) transporter. (455 aa)
	SCO7706	SCBAC12C8.07c, putative DNA-binding protein, len: 284aa: similar to many from Streptomyces coelicolor eg. TR:Q9ADL0 (EMBL:AL451182) putative DNA-binding protein 2SCK31.04c (291 aa) fasta scores; opt: 731, Z-score: 816.6, 47.778% identity in 270 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. (284 aa)
	SCO7707	SCBAC12C8.08, conserved hypothetical protein, len: 94aa: similar to TR:AAK64828 (EMBL:AE007210) hypothetical protein from Rhizobium meliloti pSymA Megaplasmid (83 aa) fasta scores; opt: 346, Z-score: 453.2, 65.753% identity (65.753% ungapped) in 73 aa overlap. (94 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO0460	SCO0461	gene:17758043	gene:17758044	Hypothetical protein SCF51A.38; SCF51A.38, unknown, len: 169 aa.	SCF76.01, possible hydrolase, partial CDS, len: >228 aa. Similar to several hypothetical proteins e.g. from Saccharomyces cerevisiae SW:YN93_YEAST (EMBLL:Z71679) (290 aa), fasta scores opt: 609 z-score: 749.0 E():0 42.4% identity in 229 aa overlap. Also weakly similar to Xanthobacter autotrophicus SW:HALO_XANAU (EMBL:M26950) haloalkane dehalogenase (EC 3.8.1.5) (310 aa), fasta scores opt: 151 z-score: 190.4 E():0.003 22.9% identity in 231 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold; SCF51A.39, possible hydrolase, partial CDS, len: >113 aa. [...]	0.872
SCO0461	SCO0460	gene:17758044	gene:17758043	SCF76.01, possible hydrolase, partial CDS, len: >228 aa. Similar to several hypothetical proteins e.g. from Saccharomyces cerevisiae SW:YN93_YEAST (EMBLL:Z71679) (290 aa), fasta scores opt: 609 z-score: 749.0 E():0 42.4% identity in 229 aa overlap. Also weakly similar to Xanthobacter autotrophicus SW:HALO_XANAU (EMBL:M26950) haloalkane dehalogenase (EC 3.8.1.5) (310 aa), fasta scores opt: 151 z-score: 190.4 E():0.003 22.9% identity in 231 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold; SCF51A.39, possible hydrolase, partial CDS, len: >113 aa. [...]	Hypothetical protein SCF51A.38; SCF51A.38, unknown, len: 169 aa.	0.872
SCO0576	SCO0577	gene:17758159	gene:17758160	SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap.	SCF55.01c, hypothetical protein, len: >231 aa; similar to SW:YIHM_ECOLI (EMBL:L19201) Escherichia coli hypothetical 36.9 KD protein in GlnA-Rbn intergenic region, 326 aa; fasta scores: opt: 188 z-score: 232.7 E(): 1.4e-05; 22.1% identity in 217 aa overlap; SC5G5.09c, conserved hypothetical protein (fragment), len: >92 aa; similar to C-terminal region of TR:BAB38218 (EMBL:AP002567) Escherichia coli O157:H7 hypothetical 37.1 kDa protein ECS4795, 326 aa; fasta scores: opt: 106 Z-score: 142.9 bits: 33.0 E(): 2.4; 25.882% identity in 85 aa overlap.	0.970
SCO0576	SCO0580	gene:17758159	gene:17758163	SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap.	SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap.	0.858
SCO0576	SCO0581	gene:17758159	gene:17758164	SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap.	SCF55.05c, probable transporter protein, len: 455 aa; similar to SW:TUB4_AGRVI (EMBL:U25634) Agrobacterium vitis putative tartrate transporter Tub4, 433 aa; fasta scores: opt: 894 z-score: 1016.3 E(): 0; 42.8% identity in 432 aa overlap and to SW:PHT1_PSEPU (EMBL:D13229) Pseudomonas putida phthalate transporter Pht1, 451 aa; fasta scores: opt: 745 z-score: 847.5 E(): 0; 30.8% identity in 435 aa overlap. Contains match to Pfam entry PF00083 sugar_tr, Sugar (and other) transporter.	0.903
SCO0577	SCO0576	gene:17758160	gene:17758159	SCF55.01c, hypothetical protein, len: >231 aa; similar to SW:YIHM_ECOLI (EMBL:L19201) Escherichia coli hypothetical 36.9 KD protein in GlnA-Rbn intergenic region, 326 aa; fasta scores: opt: 188 z-score: 232.7 E(): 1.4e-05; 22.1% identity in 217 aa overlap; SC5G5.09c, conserved hypothetical protein (fragment), len: >92 aa; similar to C-terminal region of TR:BAB38218 (EMBL:AP002567) Escherichia coli O157:H7 hypothetical 37.1 kDa protein ECS4795, 326 aa; fasta scores: opt: 106 Z-score: 142.9 bits: 33.0 E(): 2.4; 25.882% identity in 85 aa overlap.	SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap.	0.970
SCO0577	SCO0580	gene:17758160	gene:17758163	SCF55.01c, hypothetical protein, len: >231 aa; similar to SW:YIHM_ECOLI (EMBL:L19201) Escherichia coli hypothetical 36.9 KD protein in GlnA-Rbn intergenic region, 326 aa; fasta scores: opt: 188 z-score: 232.7 E(): 1.4e-05; 22.1% identity in 217 aa overlap; SC5G5.09c, conserved hypothetical protein (fragment), len: >92 aa; similar to C-terminal region of TR:BAB38218 (EMBL:AP002567) Escherichia coli O157:H7 hypothetical 37.1 kDa protein ECS4795, 326 aa; fasta scores: opt: 106 Z-score: 142.9 bits: 33.0 E(): 2.4; 25.882% identity in 85 aa overlap.	SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap.	0.863
SCO0577	SCO0581	gene:17758160	gene:17758164	SCF55.01c, hypothetical protein, len: >231 aa; similar to SW:YIHM_ECOLI (EMBL:L19201) Escherichia coli hypothetical 36.9 KD protein in GlnA-Rbn intergenic region, 326 aa; fasta scores: opt: 188 z-score: 232.7 E(): 1.4e-05; 22.1% identity in 217 aa overlap; SC5G5.09c, conserved hypothetical protein (fragment), len: >92 aa; similar to C-terminal region of TR:BAB38218 (EMBL:AP002567) Escherichia coli O157:H7 hypothetical 37.1 kDa protein ECS4795, 326 aa; fasta scores: opt: 106 Z-score: 142.9 bits: 33.0 E(): 2.4; 25.882% identity in 85 aa overlap.	SCF55.05c, probable transporter protein, len: 455 aa; similar to SW:TUB4_AGRVI (EMBL:U25634) Agrobacterium vitis putative tartrate transporter Tub4, 433 aa; fasta scores: opt: 894 z-score: 1016.3 E(): 0; 42.8% identity in 432 aa overlap and to SW:PHT1_PSEPU (EMBL:D13229) Pseudomonas putida phthalate transporter Pht1, 451 aa; fasta scores: opt: 745 z-score: 847.5 E(): 0; 30.8% identity in 435 aa overlap. Contains match to Pfam entry PF00083 sugar_tr, Sugar (and other) transporter.	0.923
SCO0580	SCO0576	gene:17758163	gene:17758159	SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap.	SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap.	0.858
SCO0580	SCO0577	gene:17758163	gene:17758160	SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap.	SCF55.01c, hypothetical protein, len: >231 aa; similar to SW:YIHM_ECOLI (EMBL:L19201) Escherichia coli hypothetical 36.9 KD protein in GlnA-Rbn intergenic region, 326 aa; fasta scores: opt: 188 z-score: 232.7 E(): 1.4e-05; 22.1% identity in 217 aa overlap; SC5G5.09c, conserved hypothetical protein (fragment), len: >92 aa; similar to C-terminal region of TR:BAB38218 (EMBL:AP002567) Escherichia coli O157:H7 hypothetical 37.1 kDa protein ECS4795, 326 aa; fasta scores: opt: 106 Z-score: 142.9 bits: 33.0 E(): 2.4; 25.882% identity in 85 aa overlap.	0.863
SCO0580	SCO0581	gene:17758163	gene:17758164	SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap.	SCF55.05c, probable transporter protein, len: 455 aa; similar to SW:TUB4_AGRVI (EMBL:U25634) Agrobacterium vitis putative tartrate transporter Tub4, 433 aa; fasta scores: opt: 894 z-score: 1016.3 E(): 0; 42.8% identity in 432 aa overlap and to SW:PHT1_PSEPU (EMBL:D13229) Pseudomonas putida phthalate transporter Pht1, 451 aa; fasta scores: opt: 745 z-score: 847.5 E(): 0; 30.8% identity in 435 aa overlap. Contains match to Pfam entry PF00083 sugar_tr, Sugar (and other) transporter.	0.820
SCO0581	SCO0576	gene:17758164	gene:17758159	SCF55.05c, probable transporter protein, len: 455 aa; similar to SW:TUB4_AGRVI (EMBL:U25634) Agrobacterium vitis putative tartrate transporter Tub4, 433 aa; fasta scores: opt: 894 z-score: 1016.3 E(): 0; 42.8% identity in 432 aa overlap and to SW:PHT1_PSEPU (EMBL:D13229) Pseudomonas putida phthalate transporter Pht1, 451 aa; fasta scores: opt: 745 z-score: 847.5 E(): 0; 30.8% identity in 435 aa overlap. Contains match to Pfam entry PF00083 sugar_tr, Sugar (and other) transporter.	SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap.	0.903
SCO0581	SCO0577	gene:17758164	gene:17758160	SCF55.05c, probable transporter protein, len: 455 aa; similar to SW:TUB4_AGRVI (EMBL:U25634) Agrobacterium vitis putative tartrate transporter Tub4, 433 aa; fasta scores: opt: 894 z-score: 1016.3 E(): 0; 42.8% identity in 432 aa overlap and to SW:PHT1_PSEPU (EMBL:D13229) Pseudomonas putida phthalate transporter Pht1, 451 aa; fasta scores: opt: 745 z-score: 847.5 E(): 0; 30.8% identity in 435 aa overlap. Contains match to Pfam entry PF00083 sugar_tr, Sugar (and other) transporter.	SCF55.01c, hypothetical protein, len: >231 aa; similar to SW:YIHM_ECOLI (EMBL:L19201) Escherichia coli hypothetical 36.9 KD protein in GlnA-Rbn intergenic region, 326 aa; fasta scores: opt: 188 z-score: 232.7 E(): 1.4e-05; 22.1% identity in 217 aa overlap; SC5G5.09c, conserved hypothetical protein (fragment), len: >92 aa; similar to C-terminal region of TR:BAB38218 (EMBL:AP002567) Escherichia coli O157:H7 hypothetical 37.1 kDa protein ECS4795, 326 aa; fasta scores: opt: 106 Z-score: 142.9 bits: 33.0 E(): 2.4; 25.882% identity in 85 aa overlap.	0.923
SCO0581	SCO0580	gene:17758164	gene:17758163	SCF55.05c, probable transporter protein, len: 455 aa; similar to SW:TUB4_AGRVI (EMBL:U25634) Agrobacterium vitis putative tartrate transporter Tub4, 433 aa; fasta scores: opt: 894 z-score: 1016.3 E(): 0; 42.8% identity in 432 aa overlap and to SW:PHT1_PSEPU (EMBL:D13229) Pseudomonas putida phthalate transporter Pht1, 451 aa; fasta scores: opt: 745 z-score: 847.5 E(): 0; 30.8% identity in 435 aa overlap. Contains match to Pfam entry PF00083 sugar_tr, Sugar (and other) transporter.	SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap.	0.820
SCO7706	SCO7707	gene:17765366	gene:17765367	SCBAC12C8.07c, putative DNA-binding protein, len: 284aa: similar to many from Streptomyces coelicolor eg. TR:Q9ADL0 (EMBL:AL451182) putative DNA-binding protein 2SCK31.04c (291 aa) fasta scores; opt: 731, Z-score: 816.6, 47.778% identity in 270 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix.	SCBAC12C8.08, conserved hypothetical protein, len: 94aa: similar to TR:AAK64828 (EMBL:AE007210) hypothetical protein from Rhizobium meliloti pSymA Megaplasmid (83 aa) fasta scores; opt: 346, Z-score: 453.2, 65.753% identity (65.753% ungapped) in 73 aa overlap.	0.613
SCO7707	SCO7706	gene:17765367	gene:17765366	SCBAC12C8.08, conserved hypothetical protein, len: 94aa: similar to TR:AAK64828 (EMBL:AE007210) hypothetical protein from Rhizobium meliloti pSymA Megaplasmid (83 aa) fasta scores; opt: 346, Z-score: 453.2, 65.753% identity (65.753% ungapped) in 73 aa overlap.	SCBAC12C8.07c, putative DNA-binding protein, len: 284aa: similar to many from Streptomyces coelicolor eg. TR:Q9ADL0 (EMBL:AL451182) putative DNA-binding protein 2SCK31.04c (291 aa) fasta scores; opt: 731, Z-score: 816.6, 47.778% identity in 270 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix.	0.613