STRINGSTRING
SCO1011 SCO1011 SCO1012 SCO1012 SCO1013 SCO1013 SCO1014 SCO1014 SCO1015 SCO1015 SCO1016 SCO1016 SCO1336 SCO1336 SCO1422 SCO1422 SCO1423 SCO1423 SCO1424 SCO1424 SCO2034 SCO2034 SCO2074 SCO2074 SCO7822 SCO7822 SCP1.162c SCP1.162c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO10112SCG2.24c, hypothetical protein, len: 634 aa; similar to TR:Q00509 (EMBL:X6451) Streptomyces ambofaciens hypothetical SrmR protein, 604 aa; fasta scores: opt: 952 z-score: 1028.3 E(): 0; 36.5% identity in 600 aa overlap. Contains Pfam match to entry PF01590 GAF, GAF domain. (634 aa)
SCO10122SCG2.25c, probable oxidoreductase, len: 266 aa; similar to SW:BDHA_ALCEU (EMBL:AF145230) Alcaligenes eutrophus D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) HbdH1, 258 aa; fasta scores: opt: 586 z-score: 655.1 E(): 5.8e-29; 39.3% identity in 257 aa overlap. Contains Pfam matches to entries PF00106 adh_short, short chain dehydrogenase and PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus and match to Prosite entry PS00061 Short-chain dehydrogenases/reductases family signature; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
SCO10132SCG2.26c, possible mut-like protein, len: 159 aa; similar to TR:Q9K3X1 (EMBL:AL359988) Streptomyces coelicolor putative mut-like protein SCD10.05c, 184 aa; fasta scores: opt: 203 z-score: 264.6 E(): 3.2e-07; 35.7% identity in 126 aa overlap. Contains Pfam match to entry PF00293 mutT, Bacterial mutT protein and match to Prosite entry PS00893 mutT domain signature. (159 aa)
SCO1014Putative transferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (537 aa)
SCO1015Hypothetical protein 2SCG2.29c; 2SCG2.29c, unknown, len: 114 aa. (114 aa)
SCO10162SCG2.30c, possible secreted protein, len: 274 aa. Contains possible N-terminal region signal peptide sequence. Rich in alanine and proline amino acid residues. High content in G+C (79.8%). (274 aa)
SCO1336Putative lipoprotein N-acyltransferase (integral membrane); Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (524 aa)
SCO1422Putative membrane protein; SC6D7.17, possible membrane protein, len: 194 aa. Contains possible membrane spanning hydrophobic domains. (194 aa)
SCO1423Putative glycosyl transferase; SC6D7.16, possible glycosyl transferase, len: 302 aa. Similar to many eukaryotic dolichol-phosphate-mannose synthases e.g. Mus musculus (Mouse) TR:O70152 (EMBL:AB004789) (260 aa), fasta scores opt: 474 z-score: 560.2 E(): 7.9e-24 37.9% identity in 227 aa overlap. Also similar to a number of Prokaryotic proteins of undefined function e.g. Mycobacterium leprae TR:O32929 (EMBL:Z98604) hypothetical 30.1 KD protein (277 aa), fasta scores opt: 917 z-score: 1076.0 E():0 52.0% identity in 281 aa overlap. Contains a Pfam match to entry PF00535 Glycos_transf_2, Gly [...] (302 aa)
SCO1424Conserved hypothetical protein SC6D7.15; SC6D7.15, unknown, len: 536 aa. Highly similar to a protein of undefined function from Mycobacterium tuberculosis TR:O53494(EMBL:AL021899) hypothetical 55.9 KD protein (534 aa), fasta scores opt: 1708 z-score: 1846.6 E():0 53.7% identity in 534 aa overlap. (536 aa)
SCO2034Putative prolipoprotein diacyleglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (343 aa)
SCO2074Putative signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (204 aa)
SCO7822Probable prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.; Belongs to the Lgt family. (317 aa)
SCP1.162cSCP1.162c, possible oxidoreductase subunit, len: 65aa; similar to the extreme C-terminus of many glycerol-3-phosphate dehydrogenases eg. TR:Q9ZBS0 (EMBL:AL034447) glycerol-3-phosphate dehydrogenase from Streptomyces coelicolor (336 aa) fasta scores; opt: 302, z-score: 432.6, E(): 1.3e-16, 76.9% identity in 65 aa overlap. Also similar to neighbouring CDS SCP1.162c fasta scores; opt: 238, z-score: 294.0, E(): 7.6e-12, 50.7% identity in 75 aa overlap. (65 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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