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SCO2018 SCO2018 SCO2179 SCO2179 SCO2635 SCO2635 SCO2643 SCO2643 SCO6444 SCO6444 SCO7331 SCO7331
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO2018SC7H2.32c, possible aminopeptidase, len: 835aa; similar to many eg. SW:AMPN_LACDL lysyl aminopeptidase from Lactobacillus delbruckii ssp. lactis (842 aa) fasta scores; opt: 705, z-score: 805.5, E(): 0, (27.7% identity in 622 aa overlap). Also similar to TR:O53194 (EMBL:AL021246) aminopeptidase from Mycobacterium tuberculosis (861 aa) fasta scores; opt: 1490, z-score: 1707.1, E(): 0, (39.6% identity in 867 aa overlap). Contains Pfam match to entry PF01433 Peptidase_M1, Peptidase family M1 and Prosite match to PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. (835 aa)
SCO2179Putative aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (517 aa)
SCO2635SC8E4A.05, probable aminopeptidase, len: 833 aa; similar to SW:AMPN_STRLI (EMBL:L23172) Streptomyces lividans aminopeptidase N (EC 3.4.11.2) PepN, 857 aa; fasta scores: opt: 3002 z-score: 3413.5 E(): 0; 56.5% identity in 832 aa overlap, to TR:O53194 (EMBL:AL021246) Mycobacterium tuberculosis aminopeptidase MTV008.23, 861 aa; fasta scores: opt: 2215 z-score: 2517.8 E(): 0; 50.8% identity in 837 aa overlap and to S. coelicolor St8E4A.13, pepN, 857 aa; fasta scores: opt: 2998 z-score: 2999.1 E(): 0; 55.8% identity in 842 aa overlap. Contains Pfam match to entry PF01433 Peptidase_M1, Pepti [...] (833 aa)
SCO2643SC8E4A.13, pepN, aminopeptidase N, len: 857 aa; identical to SW:AMPN_STRLI (EMBL:L23172) Streptomyces lividans aminopeptidase N (EC 3.4.11.2) PepN, 857 aa and similar to SW:AMPN_LACLA (EMBL:D38040) Lactococcus lactis aminopeptidase N (EC 3.4.11.2) PepN, 848 aa; fasta scores: opt: 738 z-score: 846.7 E(): 0; 33.4% identity in 440 aa overlap and to S. coelicolor SC8E4A.05, 833 aa; fasta scores: opt: 2998 z-score: 2943.4 E(): 0; 55.8% identity in 842 aa overlap. Contains Pfam match to entry PF01433 Peptidase_M1, Peptidase family M1 and match ot Prosite entry PS00142 Neutral zinc metallopep [...] (857 aa)
SCO6444SC9B5.11, probable gamma-glutamyl transferase, len: 647 aa; similar to many gamma-glutamyl transferases eg. TR:Q54353 (EMBL:X79146) LmbA, gamma-glutamyl transferase involved in lincomycin production in Streptomyces lincolnensis 78-11 (601 aa) fasta scores; opt: 871, z-score: 1756.8, E(): 0, (48.1% identity in 619 aa overlap). Also similar to TR:O54174 (EMBL:AL021411) probable transferase (606aa) from Streptomyces coelicolor fasta scores: opt: 953, z-score: 1203.1, E(): 0, (53.7% identity in 635 aa overlap). Contains Pfam match to entry PF01019 G_glu_transpept, Gamma-glutamyltranspeptidase. (647 aa)
SCO7331Conserved hypothetical protein SC4G10.10c; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (363 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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