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SCO4490 SCO4490 SCO4491 SCO4491 SCO4492 SCO4492 SCO4494 SCO4494 SCO4506 SCO4506
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO4490SCD69.10, putative decarboxylase, len: 485 aa; similar to SW:Y209_ARCFU (EMBL:AE001091) Archaeoglobus fulgidus hypothetical protein AF0209, 481 aa; fasta scores: opt: 1557 z-score: 1800.8 E(): 0; 48.6% identity in 484 aa overlap and to SW:P26615 (UBID_ECOLI) 3-Octaprenyl-4-hydroxybenzoate carboxy-lyase from Escherichia coli (497 aa) fasta scores; opt: 1293, Z-score: 1478.5, 40.162% identity (41.336% ungapped) in 493 aa overlap. Contains Pfam match to entry PF01977 UPF0096, Protein of unknown function. (485 aa)
SCO4491SCD69.11, probable octaprenyltransferase, len: 301 aa; similar to TR:AAF10428 (EMBL:AE001939) Deinococcus radiodurans 4-hydroxybenzoate octaprenyltransferase DR0851, 313 aa; fasta scores: opt: 794 z-score: 949.5 E(): 0; 44.7% identity in 302 aa overlap and to SW:UBIA_ECOLI (EMBL:M93136) Escherichia coli 4-hydroxybenzoate octaprenyltransferase (EC 2.5.1.-) UbiA, 290 aa; fasta scores: opt: 299 z-score: 362.7 E(): 9.7e-13; 27.9% identity in 276 aa overlap. Contains Pfam match to entry PF01040 UbiA, UbiA prenyltransferase family. Contains also possible hydrophobic membrane spanning regions. (301 aa)
SCO4492Putative octaprenyl carboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (216 aa)
SCO4494Conserved hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
SCO4506Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnA subfamily. (282 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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