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SCO3420 SCO3420 SCO5424 SCO5424 SCO5425 SCO5425 SCO5576 SCO5576 SCO6195 SCO6195
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO3420SCE9.27c, probable aldehyde dehydrogenase, len: 486 aa; highly similar to many NAD-linked aldehyde dehydrogenases e.g. SW:XYLC_PSEPU (EMBL:U15151), xylC, Pseudomonas putida benzaldehyde dehydrogenase [NAD+] from TOL plasmid pWW0 (487 aa), fasta scores; opt: 1244 z-score: 1420.3 E(): 0, 41.5% identity in 479 aa overlap. Similar to others from S.coelicolor e.g. TR:O88069 (EMBL:AL031541) probable aldehyde dehydrogenase (483 aa) (40.0% identity in 448 aa overlap). Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase, score 491.30, E-value 7.6e-144, PS00687 Aldehyde dehydroge [...] (486 aa)
SCO5424Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (407 aa)
SCO5425Phosphate acetyltransferase (fragment); Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
SCO5576SC7A1.20, acy, possible acylphosphatase, len: 93aa; similar to SW:ACYP_MYCTU putative acylphosphatase from Mycobacterium tuberculosis (93 aa) opt: 345, z-score: 576.5, E(): 8.2e-25, (58.9% identity in 90 aa overlap) and SW:ACYO_CHICK acylphosphatase from chicken (Gallus gallus) (98 aa) opt: 150, z-score: 208.0, E(): 0.00027, (45.0% identity in 60 aa overlap). Contains PS00150 Acylphosphatase signature 1. While acylphosphatases have been so far only characterized in vertebrates, there are a number of bacterial and archebacterial hypothetical proteins that are highly similar to that enzy [...] (93 aa)
SCO6195SC2G5.16, probable acetyl-coenzyme A synthetase, len:558 aa; similar to many e.g. SW:ACSA_BACSU from Bacillus subtilis (572 aa) fasta scores; opt: 798, z-score: 878.3,E():0, (31.8% identity in 537 aa overlap). Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31. Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31. (558 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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