STRINGSTRING
SCO0291 SCO0291 SCO0353 SCO0353 SCO0434 SCO0434 SCO0454 SCO0454 SCO2907 SCO2907 SCO2945 SCO2945 SCO0532 SCO0532 SCO0539 SCO0539 SCO0661 SCO0661 SCO0811 SCO0811 SCO0901 SCO0901 SCO0951 SCO0951 SCO2979 SCO2979 SCO3196 SCO3196 SCO3455 SCO3455 SCO3483 SCO3483 SCO3504 SCO3504 SCO4057 SCO4057 SCO5232 SCO5232 SCO5233 SCO5233 SCO5429 SCO5429 SCO6006 SCO6006 SCO6086 SCO6086 SCO6230 SCO6230 SCO6567 SCO6567 SCO6602 SCO6602 SCO1057 SCO1057 SCO1064 SCO1064 SCO1538 SCO1538 SCO1659 SCO1659 SCO1887 SCO1887 SCO1899 SCO1899 SCO2229 SCO2229 SCO2230 SCO2230 SCO2231 SCO2231 SCO2405 SCO2405 SCO2433 SCO2433 SCO2659 SCO2659 SCO2746 SCO2746 SCO2796 SCO2796 SCO2905 SCO2905 SCO2906 SCO2906 SCO7504 SCO7504 SCO7166 SCO7166 SCO7410 SCO7410 SCO7012 SCO7012 SCO7029 SCO7029 SCO7488 SCO7488 SCO7776 SCO7776 SCO7556 SCO7556 SCO0066 SCO0066 SCO0136 SCO0136 SCO0137 SCO0137 SCO0271 SCO0271
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO0291SCF85.19, possible binding protein dependent transport protein, len: 300 aa. Similar to many including: Streptomyces lividans TR:Q9ZI17 (EMBL; AF043654) BxlF (317 aa), fasta scores opt: 873 z-score: 1049.2 E(): 0 44.0% identity in 298 aa overlap and Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661)putative binding protein dependent transport protein SCE134.05C (327 aa), fasta scores opt: 551 z-score: 664.3 E(): 1.2e-29 32.7% identity in 294 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and a PS0040 [...] (300 aa)
SCO0353SCF41.12, possible binding-protein-dependent transport protein, len: 303 aa. Similar to many including: Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661) putative binding protein dependent transport protein SCE134.05c (327 aa), fasta scores opt: 560 z-score: 661.2 E(): 1.8e-29 35.5% identity in 301 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains multiple potential membrane-spanning hydrophobic domains. (303 aa)
SCO0434SCF51A.12, malX, sugar phosphotransferase, len: 549 aa. Highly similar to Escherichia coli SW:PTOA_ECOLI (EMBL; M60722) PTS system, maltose and glucose-specific II ABC component (maltose and glucose-permease II ABC component) (phosphotransferase enzyme II, ABC component) (EC 2.7.1.69) (523 aa), fasta scores opt: 1852 z-score: 2064.1 E():0 59.5% identity in 543 aa overlap. Contains a Pfam match to entry PF00367 PTS_EIIB, phosphotransferase system, EIIB and a Prosite hit to PS01035 PTS EIIB domains cysteine phosphorylation site signature. Contains multiple possible membrane spanning hydr [...] (549 aa)
SCO0454SCF51A.32, probable binding-protein dependent transport protein, len: 313 aa. Similar to many including: Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661) putative protein SCE134.05C (327 aa), fasta scores opt: 479 z-score: 546.7 E(): 4.3e-23 31.4% identity in 315 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and a Prosite hit to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains multiple possible membrane spanning hydrophobic domains. (313 aa)
SCO2907Putative PTS transmembrane component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine (GlcNAc) transport. High-affinity permease, which exhibits a narrow specificity for GlcNAc. Essential for C-signaling between vegetative growth and development. (416 aa)
SCO2945SCE59.04c, possible sugar transporter membrane protein, len: 316 aa; similar to TR:CAB59589 (EMBL:AL132662) Streptomyces coelicolor putative sugar transporter inner membrane protein SCF11.12, 302 aa; fasta scores: and to TR:CAB55533 (EMBL:AL117322) Streptomyces coelicolor putative binding-protein-dependent transport protein SCF1.13, 317 aa; fasta scores: opt: 527 z-score: 611.6 E(): 1.2e-26; 33.1% identity in 302 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains also possible hydrophobic membrane [...] (316 aa)
SCO0532SCF11.12, probable sugar transporter membrane protein, len: 302 aa; similar to TR:CAB55533 (EMBL:Y07706) Streptomyces coelicolor inner membrane protein MalF, 300 aa; fasta scores: opt: 493 z-score: 600.8 E(): 4.3e-26; 32.6% identity in 291 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and a prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature. (302 aa)
SCO0539SCF11.19, probable sugar transporter membrane protein, len: 316 aa; similar to TR:CAB52981 (EMBL:AL109950) Streptomyces coelicolor putative integral membrane permease, 319 aa; fasta scores: opt: 606 z-score: 689.2 E(): 5.1e-31; 34.9% identity in 312 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and a prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature. Contains probable N-terminal signal sequence. (316 aa)
SCO0661SCF91.21, possible binding protein dependent transport protein, len: 328 aa. Similar to many membrane transport proteins e.g. Escherichia coli SW:UGPA_ECOLI(EMBL:X13141) SN-glycerol-3-phosphate transport system permease protein (295 aa), fasta scores opt: 393 z-score: 465.7 E(): 1.5e-18 28.7% identity in 282 aa overlap and Streptomyces coelicolor TR:CAB41203(EMBL:AL049661) putative binding protein dependent transport protein (327 aa), fasta scores opt: 452 z-score: 533.8 E(): 2.4e-22 28.2% identity in 326 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-de [...] (328 aa)
SCO0811Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (505 aa)
SCO0901Hypothetical protein SCM1.34c; SCM1.34c, unknown, len: 362 aa. Contains an inverted repeat. (362 aa)
SCO0951SCM11.06c, probable transport system permease protein, len: 310 aa; similar to TR:P73352 (EMBL:D90905) Synechocystis sp. lactose transport system permease protein LacF, 298 aa; fasta scores: opt: 750 z-score: 885.7 E(): 0; 44.9% identity in 292 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and to prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. (310 aa)
SCO2979SCE50.07, possible integral membrane transport protein, len: 427 aa; N-terminal and C-terminal regions both similar to TR:Q55472 (EMBL:D64006) Synechocystis sp. membrane bound sugar transport protein, 279 aa; fasta scores: opt: 307 z-score: 333.7 E(): 3.8e-11; 26.5% identity in 412 aa overlap. Contains Pfam match in C-terminal region to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match also in C-terminal region to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains possible N-termina [...] (427 aa)
SCO3196SCE22.13c, probable fructose-specific permease, len: 699 aa; similar to SW:PTFB_ECOLI (EMBL:M23196) Escherichia coli PTS system, fructose-specific IIBC component (EIIBC-fru) FruA 563 aa; fasta scores: opt: 1006 z-score: 1038.9 E(): 0; 43.7% identity in 583 aa overlap. Contains match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible hydrophobic membrane spanning regions in C-terminal domain. (699 aa)
SCO3455SCE46.12c, possible ABC-transporter transport protein, len: 285 aa; similar to TR:O57756 (EMBL:AP000001) Pyrococcus horikoshii 284 aa long hypothetical sugar transport membrane protein, 284 aa; fasta scores: opt: 281 z-score: 329.5 E(): 5.2e-11; 26.6% identity in 278 aa overlap and to SW:UGPA_ECOLI (EMBL:X13141) Escherichia coli SN-glycerol-3-phosphate transport system permease protein UgpA, 295 aa; fasta scores: opt: 233 z-score: 274.6 E(): 6e-08; 28.7% identity in 279 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membra [...] (285 aa)
SCO3483SCE65.19c, probable integral membrane transport protein, len: 315 aa; similar to TR:O50452 (EMBL:AL021006) Mycobacterium tuberculosis probable sugar transport protein MTV006.08, 307 aa; fasta scores: opt: 542 z-score: 668.9 E(): 7e-30; 32.6% identity in 288 aa overlap. Contains match to Pfam entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and possible N-terminal region signal peptide sequence. (315 aa)
SCO3504SCE134.05c, possible binding protein dependent transport protein, len: 327aa; similar to many egs. SW:YURN_BACSU hypothetical ABC transporter permease from Bacillus subtilis (292 aa) fasta scores; opt: 586, z-score: 707.9, E(): 4.1e-32, (32.4% identity in 287 aa overlap) and SW:UGPA_ECOLI Sn-glycerol-3-phosphate transport permease from Escherichia coli (295 aa) fasta scores; opt: 583, z-score: 704.3, E(): 6.5e-32, (33.8% identity in 290 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to [...] (327 aa)
SCO40572SCD60.23c, probable transport integral membrane protein, len: 296 aa; similar to SW:AQP3_HUMAN (EMBL:AB001325) Homo sapiens aquaporin 3 Aqp3, 292 aa; fasta scores: opt: 571 z-score: 644.7 E(): 2.4e-28; 40.4% identity in 275 aa overlap. Contains Pfam match to entry PF00230 MIP, Major intrinsic protein and match to Prosite entry PS00221 MIP family signature; Belongs to the MIP/aquaporin (TC 1.A.8) family. (296 aa)
SCO5232Putative sugar transporter sugar binding protein; Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Binds specifically to (GlcNAc)2. Can also bind to GlcNAc, (GlcNAc)3, (GlcNAc)4 and (GlcNAc)5, but it exhibits the highest affinity for (GlcNAc)2. Involved in the control of morphological differentiation. (425 aa)
SCO5233Putative sugar transporter integral membrane protein; Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. (328 aa)
SCO5429SC6A11.05c, possible integral membrane transport protein, len: 313 aa; similar to many proposed transport proteins e.g. TRNEW:CAB55533(EMBL:AL117322) putative integral membrane transport protein from Streptomyces coelicolor (317 aa) fasta scores; opt: 561, z-score: 649.2, E(): 9.4e-29, 34.4% identity in 314 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible membrane-spanning hydrophobic regions. (313 aa)
SCO6006Probable transmembrane transport protein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. (353 aa)
SCO6086SCBAC1A6.10, probable transport system integral membrane protein, len: 315 aa; similar to TR:P73352 (EMBL:D90905) Synechocystis sp. lactose transport system permease protein LacF, 298 aa; fasta scores: opt: 630 z-score: 734.0 E(): 0; 38.6% identity in 298 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and possible hydrophobic membrane spanning regions. (315 aa)
SCO6230SC2H4.12c, probable sugar transport system permease protein, len: 324 aa; similar to many e.g. AMYD_THETU potential starch degradation products transport system permease (292 aa), fasta scores; opt: 479 z-score: 571.8 E(): 1.3e-24, 28.8% identity in 281 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, score 58.80, E-value 1.2e-13. (324 aa)
SCO6567SC3F9.02, ABC transporter ATP binding protein, len:505 aa; similar to many sugar transport proteins e.g. ARAG_ECOLI l-arabinose transport atp-binding protein (504 aa), fasta scores; opt: 1312 z-score: 1412.8 E(): 0, 42.1% identity in 501 aa overlap andRBSA_HAEIN ribose transport atp-binding protein rbsA (493 aa), fasta scores; opt: 1160 z-score: 1216.7 E(): 0, 40.7% identity in 489 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature and Pfam match to entry ABC_tran PF00005, ABC transporters, score 197.70. (505 aa)
SCO6602SC8A6.23, probable transmembrane sugar transport pro tein, len: 342 aa; similar to e.g. S. coelicolor TR:P72398 (EMBL:Y07706) putative maltose permease malF (334 aa), fast a scores; opt: 494 z-score: 521.6 E(): 8.2e-22, 32.6% ident ity in 322 aa overlap. Contains PS00017 ATP/GTP-binding sit e motif A (P-loop), PS00402 Binding-protein-dependent trans port systems inner membrane comp signature and Pfam match t o entry PF00528 BPD_transp, Binding-protein-dependent trans port systems inner membrane component, score 42.00, E-value 1.3e-08. (342 aa)
SCO1057SCG22.03, possible sugar transport integral membrane protein, len: 321 aa; similar to TR:Q9RK91 (EMBL:AL117322) Streptomyces coelicolor putative binding-protein-dependent transport protein SCF1.13, 317 aa; fasta scores: opt: 681 z-score: 798.6 E(): 0; 35.0% identity in 317 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (321 aa)
SCO1064SCG22.10c, probable sugar transport integral membrane protein, len: 311 aa; similar to TR:AAF37728 (EMBL:AF086819) Thermomonospora fusca cellobiose transport permease BglA, 302 aa; fasta scores: opt: 664 z-score: 802.8 E(): 0; 38.6% identity in 280 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (311 aa)
SCO1538SCL2.28c, probable transport system membrane protein, len: 328 aa; similar to SW:YESP_BACSU (EMBL:Z99107) Bacillus subtilis probable ABC transporter permease protein YesP, 309 aa; fasta scores: opt: 1013 z-score: 1146.0 E(): 0; 48.8% identity in 301 aa overlap and to TR:CAB59596 (EMBL:AL132662) Streptomyces coelicolor probable sugar transporter inner membrane protein SCF11.19, 316 aa; fasta scores: opt: 608 z-score: 690.8 E(): 4.4e-31; 32.8% identity in 320 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component [...] (328 aa)
SCO1659Putative glycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
SCO1887SCI7.05c, possible integral membrane transport protein, len: 298aa; similar to many eg. TR:O51924 (EMBL:AF012836) inner membrane protein, MalF from the trehalose/maltose transport system of the hyperthermophilic archaeon Thermococcus litoralis (300 aa) fasta scores; opt: 681, z-score: 814.3, E(): 0, (37.5% identity in 285 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible membrane spanni [...] (311 aa)
SCO1899SCI7.17, possible integral membrane sugar transport protein, len: 314aa; similar to many eg. TR:O30832 (EMBL:AF018073) sorbitol/mannitol transport inner membrane protein from Rhodobacter sphaeroides (290 aa) fasta scores; opt: 722, z-score: 829.0, E(): 0, (40.6% identity in 276 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible membrane spanning hydrophobic regions. (314 aa)
SCO2229SC10B7.24c, malG, putative maltose permease, len: 303 aa; identical to previously sequenced TR:P72399 (EMBL:Y07706) Streptomyces coelicolor putative maltose permease MalG, 302 aa and similar to SW:MALG_ECOLI (EMBL:X02871) Escherichia coli maltose transport system permease protein MalG, 296 aa; fasta scores: opt: 476 z-score: 570.0 E(): 2.3e-24; 34.1% identity in 293 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane [...] (303 aa)
SCO2230SC10B7.25c, malF, putative maltose permease, len: 334 aa; identical to previously sequenced TR:P72398 (EMBL:Y07706) Streptomyces coelicolor putative maltose permease MalF, 334 aa and similar to SW:MALF_ECOLI (EMBL:J01648) Escherichia coli maltose transport system permease protein MalF, 514 aa; fasta scores: opt: 424 z-score: 504.4 E(): 1e-20; 33.9% identity in 239 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane c [...] (334 aa)
SCO2231SC10B7.26c, malE, putative maltose-binding protein, len: 423 aa; identical to previously sequenced TR:P72397 (EMBL:Y07706) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa and similar to SW:MALX_STRPN (EMBL:L08611) Streptococcus pneumoniae maltose/maltodextrin-binding protein precursor MalX, 423 aa; fasta scores: opt: 431 z-score: 470.1 E(): 8.4e-19; 28.1% identity in 434 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and two matches to Prosite entries PS00013 Prokaryotic membrane lipoprotein lipid a [...] (423 aa)
SCO2405SC4A7.24, probable sugar-transport ATP binding protein, len: 513 aa; similar to TR:AAD45713 (EMBL:AF160811) Bacillus stearothermophilus L-arabinose transport, ATP binding protein AraG, 513 aa; fasta scores: opt: 2220 z-score: 2417.4 E(): 0; 65.5% identity in 510 aa overlap and to SW:ALSA_ECOLI (EMBL:U14003) Escherichia coli D-allose transport ATP-binding protein AlsA, 510 aa; fasta scores: opt: 1200 z-score: 1308.3 E(): 0; 40.7% identity in 514 aa overlap. Contains two Pfam matches to entry PF00005 ABC_tran, ABC transporter and two matches to Prosite entries PS00017 ATP/GTP-binding sit [...] (525 aa)
SCO2433SCC24.04c, possible sugar transporter membrane protein, len: 313 aa; similar to TR: CAB59596(EMBL:AL132662) Streptomyces coelicolor probable sugar transporter inner membrane protein SCF11.19, 316 aa; fasta scores: opt: 533 z-score: 637.4 E(): 4.5e-28; 36.2% identity in 304 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions. (313 aa)
SCO2659SC6D10.02, possible sugar transport system permease protein, len: 314 aa; similar to TR:Q9X6C4 (EMBL:AF135398) Thermus brockianus putative integral membrane protein BdtF, 280 aa; fasta scores: opt: 498 z-score: 582.4 E(): 5e-25; 35.4% identity in 288 aa overlap and to SW:LACF_AGRRD (EMBL:X66596) Agrobacterium radiobacter lactose transport system permease protein LacF, 298 aa; fasta scores: opt: 437 z-score: 511.6 E(): 4.4e-21; 31.1% identity in 315 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match [...] (314 aa)
SCO2746ABC transporter protein, ATP binding component; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (517 aa)
SCO27962SCC13.04, probable cellobiose transport permease, len: 337 aa; highly similar to TR:Q9X9R6 (EMBL:AJ009797) Streptomyces reticuli permease CebF protein, 305 aa; fasta scores: opt: 1416 z-score: 1722.4 E(): 0; 67.9% identity in 296 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible hydrophobic membrane spanning regions. (337 aa)
SCO2905Hypothetical protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine (GlcNAc) transport. (77 aa)
SCO2906SCE19A.06, possible PTS transmembrane component, len: 431 aa; similar to many PTS (phosphoenolpyruvate-dependent sugar phosphotransferase system) transmembrane and sugar-binding components e.g. TR:Q57071 (EMBL:X93360), GlcA, PtsG, Staphylococcus carnosus PTS system, glucose-specific IIABC component (675 aa), fasta scores; opt: 1120 z-score: 1260.6 E(): 0, 43.4% identity in 431 aa overlap. Similar to the adjacent CDS SCE19A.07, possible PTS transmembrane component (416 aa) (4.1% identity in 429 aa overlap).The homologous PTS family proteins have a C-terminal extension not present in thi [...] (431 aa)
SCO7504SCBAC17A6.37, possible integral membrane binding-protein-dependent transport protein, len: 316aa; similar to many eg. TR:Q9L0B3 (EMBL:AL163003) putative sugar transporter integral membrane protein from Streptomyces coelicolor (313 aa) fasta scores: opt: 949, Z-score: 1058.2, 48.867% identity (50.671% ungapped) in 309 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component; Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane span [...] (316 aa)
SCO7166SC9A4.28c, probable sugar-transporter integral membrane protein, len: 310 aa; similar to TR:Q9RJV7 (EMBL:AL117387) Streptomyces coelicolor putative binding protein dependent transport protein SCF41.12, 303 aa; fasta scores: opt: 913 z-score: 1073.6 E(): 0; 46.9% identity in 309 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible hydrophobic membrane spanning regions. (310 aa)
SCO7410SC6D11.06c, possible binding-protein dependent transport protein, len: 308 aa. Similar to many other transport proteins e.g. Streptomyces coelicolor TR:CAB61178(EMBL:AL132973) putative binding protein dependent transport protein, SCF91.21 (328 aa), fasta scores opt: 622 z-score: 709.6 E(): 4.2e-32 35.9% identity in 315 aa overlap. Contains possible membrane spanning hydrophobic domains and a Prosite hit to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inne [...] (308 aa)
SCO7012SC1H10.01c, possible binding protein dependent transport protein, partial CDS, len: > 288 aa. Almost identical to Streptomyces lividans TR:O86872(EMBL:U22894) integral membrane protein, AglF (231 aa), fasta scores opt: 1469 z-score: 1755.6 E(): 0 96.9% identity in 224 aa overlap. Also similar to Streptomyces coelicolor TR:CAB59596(EMBL:AL132662) probable sugar transporter inner membrane protein, SCF11.19 (316 aa), fasta scores opt: 575 z-score: 690.1 E(): 5.1e-31 38.1% identity in 273 aa overlap. Contains a Prosite hit to PS00402 Binding-protein-dependent transport systems inner membra [...] (319 aa)
SCO7029SC1H10.18, possible binding-protein-dependent transport protein, len: 318 aa. Almost identical to Streptomyces lividans TR:Q9ZI17 (EMBL:AF043654) putative permease, BxlF (317 aa), fasta scores opt:2000 z-score: 2320.3 E():0 98.1% identity in 318 aa overlap. Also similar to Streptococcus mutans SW:MSMF_STRMU(EMBL:M77351) multiple sugar-binding transport system permease protein, MsmF (290 aa), fasta scores opt: 447 z-score: 524.7 E(): 8.3e-22 29.9% identity in 271 aa overlap and Streptomyces coelicolor TR:CAB54176(EMBL:AL110470) putative binding-protein-dependent transport protein, SCF85 [...] (318 aa)
SCO7488SCBAC17A6.21c, possible integral membrane binding protein dependent transport protein, len: 343aa; similar to many eg. SW:Q04698 (MALC_STRPN) maltodextrin transport permease from Streptococcus pneumoniae (435 aa) fasta scores: opt: 376, Z-score: 423.7, 26.959% identity (29.153% ungapped) in 319 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to S00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane spanning regions. (343 aa)
SCO7776Hypothetical protein; SC5E9.24, unknown, len: 106 aa; some similarity to TR:Q9Z3X0 (EMBL:AF073359) 4-oxalocrotonate isomerase from Sphingomonas sp. DJ77 (77 aa) fasta scores; opt: 91, z-score: 135.8, E(): 4.3, 32.8% identity in 61 aa overlap. (106 aa)
SCO7556SC5F1.10, possible sugar transport permease, len: 331 aa; similar to TR:Q9X9R6 (EMBL:AJ009797) Streptomyces reticuli CebF protein, 305 aa; fasta scores: opt: 1258 z-score: 1401.2 E(): 0; 57.6% identity in 311 aa overlap and to TR:CAC10105 (EMBL:AL442165) Streptomyces coelicolor putative cellobiose transport permease 2SCC13.04, 337 aa; fasta scores: opt: 1343 z-score: 1424.3 E(): 0; 56.5% identity in 336 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-depe [...] (331 aa)
SCO0066SCJ4.47, possible integral membrane permease, part of a possible binding protein dependent transport system, len: 319 aa; similar to many eg. SW:LACF_AGRRD lactose transport system permease from Agrobacterium radiobacter (298 aa) fasta scores; opt: 460, z-score: 522.1, E(): 1e-21, (30.5% identity in 272 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. (319 aa)
SCO0136SCJ21.17c, probable integral membrane protein, len: 516 aa; similar to SGAT_ECOLI putative transport protein SGAT (484 aa), fasta scores; opt: 339 z-score: 341.6 E(): 1.1e-11, 28.5% identity in 414 aa overlap. Contains probable membrane spanning hydrophobic domains. (516 aa)
SCO0137Possible sugar-transport protein; SCJ21.18c, unknown, partial CDS, len >170 aa; SCJ33.01c, putative sugar-transport protein, partial CDS, len: > 138 aa. Similar to many e.g. Escherichia coli SW: PTXA_ECOLI (EMBL; U14003) unknown pentitol phosphotransferase enzyme II, A component (EC 2.7.1.69) (154 aa), fasta scores opt: 313 z-score: 403.6 E(): 4.1e-15 38.3% identity in 133 aa overlap. Overlaps with and extends into CDS SCJ21.18c. Contains a Pfam match to entry PF00359 PTS_EIIA_2, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. (266 aa)
SCO0271SCF1.13, possible binding-protein-dependent transport protein, len: 317aa; similar to many predicted membrane transporters eg. TR:CAB41203 (EMBL:AL049661) putative binding-protein-dependent transport protein from Streptomyces coelicolor (327 aa) fasta scores; opt: 624, z-score: 720.7, E(): 8.8e-33, (35.9% identity in 320 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible membrane spanning hydrophobic [...] (317 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.