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| | SCO3478 | SCE65.14c, probable dehydrogenase, len: 344 aa; similar to TR:O50095 (EMBL:AP000006) Pyrococcus horikoshii 307aa long hypothetical phosphoglycerate dehydrogenase PH1387, 307 aa; fasta scores: opt: 687 z-score: 777.1 E(): 0; 40.5% identity in 291 aa overlap and to SW:SERA_METTH (EMBL:AE000870;) Methanobacterium thermoautotrophicum D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) SerA, 525 aa; fasta scores: opt: 664 z-score: 748.1 E(): 0; 39.0% identity in 282 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases and match to Prosite [...] (344 aa) |
| | SCO0179 | SCJ1.28c,possible zinc-containing dehydrogenase, len: 356 aa. Similar to many including: Thermoanaerobacter brockii SW:ADH_THEBR (EMBL; X64841) NADP-dependent alcohol dehydrogenase (EC 1.1.1.2) (352 aa), fasta scores opt: 556 z-score: 601.1 E(): 4e-26 33.7% identity in 338 aa overlap and Halobacterium volcanii TR:O34179 (EMBL; U95372) dehydrogenase (389 aa), fasta scores opt: 715 z-score: 770.1 E(): 0 37.0% identity in 351 aa overlap. Contains a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and a PS00059 Zinc-containing alcohol dehydrogenases signature. (356 aa) |
| | SCO0199 | SCJ12.11c, probable alcohol dehydrogenase, len: 340 aa. Highly similar to many e.g. Bacillus stearothermophilus SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC 1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score: 1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. (340 aa) |
| | SCO0259 | SCF1.01, partial CDS, probable alcohol dehydrogenase, len: >167aa; similar the C-terminal region of many eg. SW:ADH3_SULSO NAD-dependent alcohol dehydrogenase from Sulfolobus solfataricus (347 aa) fasta scores; opt: 274, z-score: 304.7, E(): 1.3e-09, (31.8% identity in 170 aa overlap). Also similar to C-terminal region of TR:BAA82700 (EMBL:AB017438) from Streptomyces coelicolor (346 aa) fasta scores; opt: 372, z-score: 409.3, E(): 2e-15, (40.7% identity in 167 aa overlap); SCF20.05, probable alcohol dehydrogenase (zinc-binding), len: >236aa; similar to many eg. alcohol dehydrogenases e [...] (341 aa) |
| | SCO0263 | SCF1.05c, possible oxidoreductase, len: 371 aa; weakly similar to many e.g. TR:O69945 (EMBL:AL023862) putative oxidoreductase from Streptomyces coelicolor (430 aa) fasta scores; opt: 224, z-score: 247.7, E(): 2e-06, (26.0% identity in 392 aa overlap). Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (371 aa) |
| | SCO0338 | SCF12.17c, possible dehydrogenase, len: 179 aa; similar to the C-terminal many proposed glucose-6-phosphate dehydrogenase eg. TR:AAD36231 (EMBL:AE001772) from Thermotoga maritima (496 aa) fasta scores; opt: 314, z-score: 381.8, E(): 6.5e-14, (42.5% identity in 146 aa overlap). Contains Pfam match to entry PF00479 G6PD, Glucose-6-phosphate dehydrogenase. (179 aa) |
| | SCO0339 | SCF12.18, possible dehydrogenase, len: 189 aa; similar to a region from many proposed dehydrogenases e.g. SW:SERA_METJA D-3-phosphoglycerate dehydrogenase from Methanococcus jannaschii (524 aa) fasta scores; opt: 415, z-score: 508.1, E(): 6e-21, 40.8% identity in 179 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases. (189 aa) |
| | SCO0348 | SCF41.07, possible 2-hydroxyacid-family dehydrogenase, len: 339 aa. Similar to Mycobacterium leprae SW:SERA_MYCLE (EMBL; Z99263) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH) MLCB637.25 (528 aa), fasta scores opt: 452 z-score: 525.4 E(): 6.5e-22 36.7% identity in 286 aa overlap and Pyrococcus abyssi TR:CAB49675 (EMBL; AJ248285) SERA-like protein (307 aa), fasta scores opt: 437 z-score: 511.6 E(): 3.8e-21 32.0% identity in 309 aa overlap. Contains a Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases. (339 aa) |
| | SCO0382 | SCF62.08, probable UDP-glucose/GDP-mannose family dehydrogenase (putative secreted protein), len: 441 aa. Highly similar to many e.g. Pseudomonas syringae (pv. phaseolicola) SW: ALGD_PSESH (EMBL; AF001555) GDP-mannose 6-dehydrogenase (EC 1.1.1.132) (438 aa), fasta scores opt: 1453 z-score: 1666.9 E(): 0 49.2% identity in 445 aa overlap. Contains a Pfam match to entry PF00984 UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase family. (441 aa) |
| | SCO0387 | SCF62.13. possible bi-domain oxidoreductase, len: 726 aa. The N-terminus is similar to many Zinc-binding dehydrogenases e.g. Sinorhizobium meliloti TR:O31186 (EMBL; AF031940) alcohol dehydrogenase (340 aa), fasta scores pt: 224 z-score: 241.8 E(): 4.1e-06 25.5% identity in 333 aa overlap. The C-terminus is similar to other oxidoreductases e.g. Zymomonas mobilis SW:GFO_ZYMMO (EMBL; M97379) glucose-fructose oxidoreductase precursor (EC 1.1.99.28) (439 aa), fasta scores opt: 243 z-score: 260.3 E(): 3.8e-07 26.1% identity in 272 aa overlap. Note this CDS is also weakly similar to the C-ter [...] (726 aa) |
| | SCO0420 | SCF51.19c, possible homoserine dehydrogenase, len: 344 aa; similar to SW:DHOM_SYNY3 (EMBL:D64001) Synechocystis sp. (strain PCC 6803) homoserine dehydrogenase (EC 1.1.1.3) (HDH), 433 aa; fasta scores: opt: 284 z-score: 307.6 E(): 9.2e-10; 29.0% identity in 335 aa overlap and to TR:O26517 (EMBL:AE000826) Methanobacterium thermoautotrophicum homoserine dehydrogenase homologue MTH417, 340 aa; fasta scores: opt: 332 z-score: 359.9 E(): 1.1e-12; 30.1% identity in 335 aa overlap. Contains Prosite match to entry PS01042 Homoserine dehydrogenase signature. (344 aa) |
| | SCO0462 | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (309 aa) |
| | SCO0541 | SCF11.21, probable alpha-galactosidase, len: 441 aa; similar to SW:AGAL_BACSU (EMBL:AF008220) Bacillus subtilis alpha-galactosidase (EC 3.2.1.22) (Melibiase) MelA, 432 aa; fasta scores: opt: 1068 z-score: 1240.5 E(): 0; 39.3% identity in 427 aa overlap. (441 aa) |
| | SCO0645 | Putative Zinc-containing dehydrogenase; SCF91.05c, possible Zinc-containing dehydrogenase, len: 337 aa. Similar to many dehydrogenases including: Alcaligenes eutrophus SW:ADH_ALCEU(EMBL:J03362) alcohol dehydrogenase (EC 1.1.1.1) (366 aa), fasta scores opt: 272 z-score: 296.1 E(): 4e-09 27.0% identity in 371 aa overlap and Streptomyces coelicolor TR:Q53927(EMBL:X62373) hydroxyacyl-CoA dehydrogenase (329 aa), fasta scores opt: 308 z-score: 335.0 E(): 2.8e-11 31.8% identity in 333 aa overlap. Contains a Prosite hit to PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam mat [...] (337 aa) |
| | SCO0663 | Putative 2-hydroxyacid-family dehydrogenase; SCF91.23, possible 2-hydroxyacid-family dehydrogenase, len: 343 aa. Similar in parts to several D-3-phosphoglycerate dehydrogenases e.g. Mycobacterium tuberculosis SW:SERA_MYCTU (EMBL:AL021287) (528 aa), fasta scores opt: 450 z-score: 536.4 E(): 1.7e-22 34.1% identity in 261 aa overlap. Also similar to Streptomyces coelicolor TR:CAB55710(EMBL:AL117387) possible dehydrogenase SCF41.07 (339 aa), fasta scores opt: 927 z-score: 1106.0 E(): 0 48.6% identity in 325 aa overlap. Contains a Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2- [...] (343 aa) |
| | SCO0714 | SCF42.24, possible oxidoreductase, len: 295 aa. Identical to the previously sequenced Streptomyces coelicolor TR:Q9ZIW7 (EMBL:AF009336) Orf1 (fragment) (>195 aa). Also weakly similar to Sinorhizobium meliloti TR:O68965 (EMBL:AF059313) myo-inositol dehydrogenase (EC 1.1.1.18) (330 aa), fasta scores opt: 242 z-score: 275.5 E(): 5.9e-08 26.5% identity in 302 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (295 aa) |
| | SCO0975 | 6-phosphogluconate 1-dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa) |
| | SCO0984 | SCBAC19F3.11, possible 3-hydroxyacyl-CoA dehydrogenase, len: 289 aa; similar to many e.g. SW:P52041 (HBD_CLOAB) 3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum (282 aa) fasta scores; opt: 697, Z-score: 765.4, 40.702% identity (41.281% ungapped) in 285 aa overlap and TR:O88051 (EMBL:AL031541) putative 3-hydroxyacyl-CoA dehydrogenase SCI35.13 from Streptomyces coelicolor (303 aa) fasta scores; opt: 1134, Z-score: 1238.6, 61.538% identity (61.538% ungapped) in 286 aa overlap. Contains Pfam match to entry PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding doma [...] (289 aa) |
| | SCO1049 | SCG20A.29c, probable secreted oxidoreductase, len: 387 aa; similar to SW:GFO_ZYMMO (EMBL:M97379) Zymomonas mobilis glucose-fructose oxidoreductase precursor (EC 1.1.99.28) Gfo, 439 aa; fasta scores: opt: 287 z-score: 318.4 E(): 2.9e-10; 26.6% identity in 350 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family and possible N-terminal region signal peptide sequence. (387 aa) |
| | SCO1337 | 2SCG61.19c, possible oxidoreductase, len: 301 aa; similar to SW:P37168 (MVIM_SALTY) virulence factor MviM from Salmonella typhimurium (307 aa) fasta scores; opt: 467, z-score: 533.5, E(): 3.1e-22, 33.9% identity in 304 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (301 aa) |
| | SCO1461 | SCL6.18c, guaB2, probable inosine monophosphate dehydrogenase, len: 483 aa; similar to SW:IMDH_BACSU (EMBL:X55669) Bacillus subtilis inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) GuaB, 513 aa; fasta scores: opt: 970 z-score: 1018.4 E(): 0; 37.4% identity in 471 aa overlap. Contains Pfam match to entry PF01574 IMPDH_N, IMP dehydrogenase / GMP reductase N terminus, two matches to entry PF00571 CBS, CBS domain and to entry PF00478 IMPDH_C, IMP dehydrogenase / GMP reductase C terminus. (483 aa) |
| | SCO1498 | SC9C5.22c, aroE, shikimate 5-dehydrogenase, len: 255 aa; similar to SW:AROE_PSEAE (EMBL:X85015) Pseudomonas aeruginosa shikimate 5-dehydrogenase (EC 1.1.1.25) AroE, 274 aa; fasta scores: opt: 294 z-score: 335.8 E(): 3.1e-11; 31.3% identity in 259 aa overlap. Contains Pfam match to entry PF01488 Shikimate_DH, Shikimate / quinate 5-dehydrogenase. (255 aa) |
| | SCO1591 | SCI35.13, probable 3-hydroxyacyl-CoA dehydrogenase, len: 303 aa; similar to many e.g. SW:MMGB_BACSU probable 3-hydroxybutyryl-CoA dehydrogenase (287 aa), fasta scores; opt: 764 z-score: 1162.2 E(): 0, 45.6% identity in 283 aa overlap and SW:HBD_CLOAB 3-hydroxybutyryl-CoA dehydrogenase (282 aa), fasta scores; opt: 733 z-score: 1075.7 E(): 0, 43.6% identity in 282 aa overlap. Contains Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, score 361.30, E-value 1.1e-104. (303 aa) |
| | SCO1682 | SCI30A.03, probable zinc-binding alcohol dehydrogenase, len: 358 aa; similar to many both prokaryote and eukaryote e.g. SW:DHSO_BACSU sorbitol dehydrogenase from Bacillus subtilis (352 aa) fasta scores; opt: 616, z-score: 638.0, E(): 3.3e-28, (32.7% identity in 352 aa overlap) and DHSO_SHEEP sorbitol dehydrogenase from Ovis aries (sheep) (354 aa) fasta scores; opt: 606, z-score: 627.7, E(): 1.2e-27, (34.6% identity in 344 aa overlap). Conatins Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. (358 aa) |
| | SCO1884 | Hypothetical protein; SCI7.02c, unknown, len: 281aa. (281 aa) |
| | SCO1885 | SCI7.03c, possible oxidoreductase, len: 385 aa; similar to many proteins of undefined function eg. TR:Q45376 (EMBL:X90711) from a locus required for lipopolysaccharide biosynthesis in Bordetella pertussis (350 aa) fasta scores; opt: 232, z-score: 266.7, E(): 1.6e-07, (28.0% identity in 275 aa overlap). Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (385 aa) |
| | SCO1901 | SCI7.19, probable zinc-binding dehydrogenase, len: 329 aa; similar to many e.g. SW:DHSO_BACSU sorbitol dehydrogenase from Bacillus subtilis (352 aa) fasta scores; opt: 552, z-score: 626.6, E(): 1.4e-27, (30.1% identity in 345 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite match to PS00059 Zinc-containing alcohol dehydrogenases signature. (329 aa) |
| | SCO1937 | Putative glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa) |
| | SCO2054 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (441 aa) |
| | SCO2118 | SCE10.12c, dldh2, probable D-lactate dehydrogenase, len: 331 aa; highly similar to many members of the D-isomer specific 2-hydroxyacid dehydrogenases family, especially lactate dehydrogenases e.g. SW:LDHD_ECOLI (EMBL:U36928), LdhA, Escherichia coli D-lactate dehydrogenase (329 aa), fasta scores; opt: 843 z-score: 1010.7 E(): 0, 44.4% identity in 320 aa overlap. Similar to other dehydrogenases from S.coelicolor e.g. SC66T3.05 (EMBL:AL079348), dldh, S.coelicolor probable D-lactate dehydrogenase 337 aa) (36.3% identity in 325 aa overlap). Contains Pfam match to entry PF00389 2-Hacid_DH, D [...] (331 aa) |
| | SCO2285 | SCC75A.31, possible oxidoreductase, len: 351 aa. Similar to many Eukaryotic dimeric dihydrodiol dehydrogenases e.g. Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) TR:BAA83489(EMBL:AB021932) dimeric dihydrodiol dehydrogenase (EC 1.3.1.20) (334 aa), fasta scores opt: 741 z-score: 868.2 E():0 39.1% identity in 335 aa overlap. Also similar to Prokaryotic oxidoreductases e.g. Streptomyces antibioticus TR:AAD55450(EMBL:AF055579) putative 3-ketoreductase (328 aa), fasta scores opt: 434 z-score: 510.8 E(): 4.5e-21 34.0% identity in 300 aa overlap. Contains a Pfam match to entry [...] (351 aa) |
| | SCO2304 | SCC30.12c, possible dehydrogenase, len: 333 aa; similar to SW:DHB4_HUMAN (EMBL:X87176) Homo sapiens, estradiol 17 beta-dehydrogenase 4 (EC 1.1.1.62) Hsd17b4, 736 aa; fasta scores: opt: 611 z-score: 633.2 E(): 8e-28; 34.7% identity in 288 aa overlap. Contains Pfam match to entry PF01575 MaoC_like, MaoC like domain. (333 aa) |
| | SCO2377 | SC4A7.05c, probable aldo/keto reductase, len: 338 aa; similar to TR:Q9X5G7 (EMBL:AF124928) Streptomyces clavuligerus putative aldo/keto reductase family 2 enzyme Cvm1, 344 aa; fasta scores: opt: 916 z-score: 1035.7 E(): 0; 47.7% identity in 331 aa overlap. (338 aa) |
| | SCO2402 | SC4A7.30, possible dehydrogenase, len: 338 aa; similar to SW:TDH_ECOLI (EMBL:X06690) Escherichia coli threonine 3-dehydrogenase (EC 1.1.1.103) Tdh, 341 aa; fasta scores: opt: 468 z-score: 507.9 E(): 6.6e-21; 28.4% identity in 328 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and match to Prosite entry PS00059 Zinc-containing alcohol dehydrogenases signature. (338 aa) |
| | SCO2661 | SC6D10.04, possible sugar hydrolase, len: 421 aa; similar to SW:CELF_ECOLI (EMBL:X52890) Escherichia coli 6-phospho-beta-glucosidase (EC 3.2.1.86) CelF, 450 aa; fasta scores: opt: 556 z-score: 624.0 E(): 2.4e-27; 36.0% identity in 431 aa overlap and to SW:AGAL_ECOLI (EMBL:X04894) Escherichia coli alpha-galactosidase (EC 3.2.1.22) (melibiase) MelA, 451 aa; fasta scores: opt: 300 z-score: 338.4 E(): 1.9e-11; 25.5% identity in 459 aa overlap. (421 aa) |
| | SCO2688 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (381 aa) |
| | SCO2696 | SCC61A.17, possible 2-hydroxyacid-family dehydrogenase, len: 330 aa; similar to many e.g. SW:P35136 (SERA_BACSU) D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 519, z-score: 581.8, E(): 6e-25, 35.7% identity in 294 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases. (330 aa) |
| | SCO2752 | SCC57A.23c, possible oxidoreductase, len: 378 aa. Weakly similar to several other putative oxidoreductases e.g. Streptomyces coelicolor TR:O69945 (EMBL:AL023862) putative oxidoreductase (430 aa), fasta scores opt: 252 z-score: 300.4 E(): 2.4e-09 28.8% identity in 278 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (378 aa) |
| | SCO2847 | Putative oxidoreductase; SCE20.21, possible oxidoreductase, len: 360 aa. Similar to several other putative oxidoreductases e.g. Escherichia coli SW:YDGJ_ECOLI(EMBL:AE000258) hypothetical oxidoreductase (346 aa), fasta scores opt: 873 z-score: 972.9 E():0 45.0% identity in 353 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (360 aa) |
| | SCO2951 | SCE59.10c, probable malate oxidoreductase, len: 471 aa; similar to SW:MAOX_BACST (EMBL:M19485) Bacillus stearothermophilus NAD-dependent malic enzyme (EC 1.1.1.38) (NAD-ME) 478 aa; fasta scores: opt: 1778 z-score: 1887.0 E(): 0; 58.8% identity in 471 aa overlap and to SW:MAO2_ECOLI (EMBL:AE000333) Escherichia coli NADP-dependent malic enzyme (EC 1.1.1.40) MaeB, 759 aa; fasta scores: opt: 1092 z-score: 1158.4 E(): 0; 46.4% identity in 394 aa overlap Contains two Pfam matches to entry PF00390 malic, Malic enzyme. (471 aa) |
| | SCO3052 | SCBAC19G2.07, probable UDP-glucose 6-dehydrogenase, len: 447aa: similar to many eg. SW:O54068 (UDG_RHIME) UDP-glucose 6-dehydrogenase RkpK from Rhizobium meliloti EC:1.1.1.22 (437 aa) fasta scores; opt: 1101, Z-score: 1198.1, 43.080% identity (44.780% ungapped) in 448 aa overlap. Contains Pfam match to entry PF00984 UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase family. (447 aa) |
| | SCO3477 | SCE65.13c, possible dehydrogenase, len: 344 aa; similar to TR:CAB50292 (EMBL:AJ248287) Pyrococcus abyssi threonine 3-dehydrogenase (EC 1.1.1.103) 348 aa; fasta scores: opt: 567 z-score: 616.8 E(): 5.6e-27; 33.8% identity in 328 aa overlap and to SW:TDH_BACSU (EMBL:Z99112) threonine 3-dehydrogenase (EC 1.1.103) Tdh, 347 aa; fasta scores: opt: 544 z-score: 592.1 E(): 1.3e-25; 31.4% identity in 331 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. (344 aa) |
| | SCO3594 | SC66T3.05, dldh, probable D-lactate dehydrogenase, len: 337 aa; highly similar to many e.g. TR:O33805 (EMBL:U8296) Streptomyces toyocaensis D-lactate dehydrogenase (330 aa), fasta scores; opt: 1470 z-score: 1711.8 E(): 0,71.4% identity in 318 aa overlap. Also similar to D-specific alpha-keto acid dehydrogenases from vancomycin-resistant bacteria e.g. SW:VANH_ENTFC (EMBL:M64304), VanH, Enterococcus faecium alpha-keto acid dehydrogenase (322 aa) (61.4% identity in 316 aa overlap). Similar to other S.coelicolor putative dehydrogenases e.g. part of SerA (EMBL:AL035569) S.coelicolor probabl [...] (337 aa) |
| | SCO3834 | SCH69.04c, probable 3-Hydroxyacyl-CoA dehydrogenase, len: 504aa; similar to many eg. TR:O84980 (EMBL:AF029714) PhaC, 3-Hydroxyacyl-CoA dehydrogenase from Pseudomonas putida (505 aa) fasta scores; opt: 1512, z-score: 1634.7, E(): 0, (50.0% identity in 498 aa overlap). Contains Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase. (504 aa) |
| | SCO3877 | SCH18.14c, probable 6-phosphogluconate dehydrogenase, len: 291 aa; identical to previously sequenced TR:Q53917 (EMBL:L27063) Streptomyces coelicolor 6-phosphogluconate dehydrogenase, 291 aa and highly similar to TR:O88014 (EMBL:AL031107) S. coelicolor SC5A7.08c probable 6-phosphogluconate dehydrogenase, 293 aa; fasta scores: opt: 1654 z-score: 1688.1 E(): 0; 83.4% identity in 289 aa overlap. Contains Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogenasesand match to Prosite entry. (291 aa) |
| | SCO4055 | 2SCD60.21c, probable alcohol dehydrogenase, len: 377 aa; similar to SW:FADH_PSEPU (EMBL:D21201) Pseudomonas putida glutathione-independent formaldehyde dehydrogenase (EC 1.2.1.46) FdhA, 398 aa; fasta scores: opt: 1048 z-score: 1080.0 E(): 0; 47.9% identity in 390 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and match to Prosite entry PS00059 Zinc-containing alcohol dehydrogenases signature. (377 aa) |
| | SCO4106 | SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...] (376 aa) |
| | SCO4109 | SCD17.13, possible oxidoreductase, partial CDS, len: >136 aa. Similar to several including: Streptomyces fradiae TR:AAD41821 (EMBL; AF147704) NDP-Hexose 2,3-Enoyl reductase TYLCII (329 aa), fasta scores opt: 251 z-score: 325.2 E(): 9.3e-11 41.9% identity in 124 aa overlap and Saccharopolyspora erythraea (Streptomyces erythraeus) TR:O33936 (EMBL; U77454)EryBII (333 aa), fasta scores opt: 245 z-score: 317.5 E(): 2.5e-10 39.3% identity in 135 aa overlap; SCD17A.01, possible oxidoreductase (fragment), len: >218 aa; similar to TR:Q9RJC4 (EMBL:AL133171) Streptomyces coelicolor putative aldo/ [...] (314 aa) |
| | SCO4271 | SCD95A.04, probable NADP-dependent alcohol dehydrogenase, len: 378 aa; similar to SW:ADH_MYCTU (EMBL:AL021287) Mycobacterium tuberculosis NADP-dependent alcohol dehydrogenase (EC 1.1.1.2) Adh, 346 aa; fasta scores: opt: 986 z-score: 1074.5 E(): 0; 45.0% identity in 349 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and match to Prosite entry PS00059 Zinc-containing alcohol dehydrogenases signature. (378 aa) |
| | SCO4643 | UDP-N-acetylenoylpyruvoylglucosamine reductase; Cell wall formation. (383 aa) |
| | SCO4770 | Inosine 5' monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (501 aa) |
| | SCO4771 | SCD63.03, possible inosine-5'-monophosphate dehydrogenase, len: 374 aa; N-terminal region identical to previously sequenced TR:O86845 (EMBL:AJ010601) Streptomyces coelicolor hypothetical 38.9 kD protein (fragment), 84 aa and whole CDS similar to SW:IMDH_ECOLI (EMBL:X02209) Escherichia coli inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) GuaB, 488 aa; fasta scores: opt: 275 z-score: 311.9 E(): 6.1e-10; 29.0% identity in 376 aa overlap. Contains Pfam matches to entries PF01574 IMPDH_N, IMP dehydrogenase / GMP reductase N terminus PF00478 IMPDH_C, IMP dehydrogenase / GMP reductase C [...] (374 aa) |
| | SCO4773 | SCD63.05c, probable nucleotide-sugar dehydrogenase, len: 405 aa; similar to SW:WECC_ECOLI (EMBL:M87049) Escherichia coli UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (EC 1.1.1.-) WecC, 420 aa; fasta scores: opt: 565 z-score: 606.3 E(): 2.4e-26; 31.7% identity in 420 aa overlap. Contains Pfam match to entry PF00984 UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase family. (405 aa) |
| | SCO4827 | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits remarkably higher catalytic efficiency for oxaloacetate reduction than for malate oxidation in vitro. Shows a high specificity for NAD(H), being almost inactive with NADP(H). (329 aa) |
| | SCO4943 | 2SCK31.03, probable oxidoreductase, len: 330 aa; similar to TR:AAG05923 (EMBL:AE004681) Pseudomonas aeruginosa probable oxidoreductase PA2535, 331 aa; fasta scores: opt: 1001 z-score: 1136.6 E(): 0; 48.2% identity in 328 aa overlap. Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family. (330 aa) |
| | SCO4945 | 2SCK31.05, probable dehydrogenase, len: 346 aa; highly similar to SW:ADH_MYCTU (EMBL:AL021287) Mycobacterium bovis NADP-dependent alcohol dehydrogenase AdhC, 346 aa; fasta scores: opt: 1508 z-score: 1698.9 E(): 0; 64.5% identity in 346 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and matches to Prosite entries PS00059 Zinc-containing alcohol dehydrogenases signature and PS00017 ATP/GTP-binding site motif A (P-loop). (346 aa) |
| | SCO5050 | SCK7.23, possible nucleotide-sugar dehydrogenase, len: 443 aa; similar to TR:CAB82012 (EMBL:AL161755) Streptomyces coelicolor putative nucleotide-sugar dehydrogenase SCD63.05c, 405 aa; fasta scores: opt: 736 z-score: 812.9 E(): 0; 36.2% identity in 423 aa overlap. Contains Pfam match to entry PF00984 UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase family. (443 aa) |
| | SCO5072 | SCBAC20F6.15, ORF1 hydroxylacyl-CoA dehydrogenase, len: 307 aa; identical to previously sequenced TR:Q53926 (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA dehydrogenase ORF1, 307 aa. Contains Pfam matches to entries PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain and PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain. Contains possible hydrophobic membrane spanning region. (307 aa) |
| | SCO5261 | 2SC7G11.23, probable malate oxidoreductase, len: 409 aa; similar to SW:MAOX_BACST (EMBL:M19485) Bacillus stearothermophilus NAD-dependent malic enzyme (EC 1.1.1.38), 478 aa; fasta scores: opt: 1385 z-score: 1470.9 E(): 0; 55.0% identity in 391 aa overlap. Contains 2x Pfam matches to entry PF00390 malic, Malic enzyme. (409 aa) |
| | SCO5354 | SCBAC5H2.23, thrA, homoserine dehydrogenase, len: 429 aa; highly similar to SW:DHOM_CORGL (EMBL:Y00546) Corynebacterium glutamicum homoserine dehydrogenase (EC 1.1.1.3) Hom or ThrA, 445 aa; fasta scores: opt: 1592 z-score: 1742.3 E(): 0; 57.7% identity in 423 aa overlap. Contains Pfam matches to entries PF00742 Homoserine_dh, Homoserine dehydrogenase and PF01842 ACT, ACT domain and match to Prosite entry PS01042 Homoserine dehydrogenase signature. Note: Can participate in the biosynthesis of Methionine, Lysine and Threonine (plus following steps to Valine, Leucine and Isoleucine). (429 aa) |
| | SCO5385 | 2SC6G5.29, possible 3-hydroxybutyryl-coA dehydrogenase, len: 282 aa; similar to many eg. SW:P52041 (HBD_CLOAB) 3-hydroxybutyryl-coA dehydrogenase from Clostridium acetobutylicum (282 aa) fasta scores; opt: 806, z-score: 947.0, E(): 0, 44.6% identity in 280 aa overlap. Contains Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase and Prosite match to PS00067 3-hydroxyacyl-CoA dehydrogenase signature. (282 aa) |
| | SCO5509 | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. (310 aa) |
| | SCO5514 | Acetolactate synthase small subunit; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa) |
| | SCO5515 | SC8D9.27, serA, D-3-phosphoglycerate dehydrogenase, len: 529 aa; member of a family including egs. SW:SERA_MYCLE putative SerA, D-3-phosphoglycerate dehydrogenase from Mycobacterium leprae (528 aa) fasta scores; opt: 1889, z-score: 2032.0, E(): 0, (56.9% identity in 524 aa overlap) and SW:SERA_BACSU SerA, D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 1176, z-score: 1266.5, E(): 0, (39.7% identity in 529 aa overlap). Contains PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature, PS00670 D-isomer specific 2-hydroxyacid dehyd [...] (529 aa) |
| | SCO5522 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (347 aa) |
| | SCO5559 | SC7A1.03, gpsA, glycerol-3-phosphate dehydrogenase, len: 366aa; similar to many eg. SW:GPDA_BACSU glycerol-3-phosphate dehydrogenase from Bacillus subtilis (345 aa) fasta scores; opt: 874, z-score: 1221.4, E(): 0, (41.8% identity in 330 aa overlap). Contains a possible PS00017 ATP /GTP-binding site motif A (P-loop) and Pfam match to entry PF01210 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase, score 295.10, E-value 8.8e-85. (336 aa) |
| | SCO5694 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (418 aa) |
| | SCO5893 | Oxidoreductase; SC3F7.13, redK, probable oxidoreductase, len: 347 aa; similar to many eukaryotic steroid dehydrogenases eg. TR:Q62878 (EMBL:L17138) 3 hydroxysteroid dehydrogenase from Rattus norvegicus (373 aa), fasta scores; opt: 103 z-score: 378.9 E(): 6.6e-14, 30.4% identity in 355 aa overlap; and to Mycobacterium tuberculosis putative dehydrogenase TR:O06373 (EMBL:Z95436) MTCY15C10.18 (314 aa), fasta scores; opt: 204 z-score: 417.9 E(): 4.4e-16, 27.7% identity in 339 aa overlap. (347 aa) |
| | SCO6026 | SC1C3.14c, probable fatty acid oxidation complex alpha-subunit, similar to many e.g. FADB_ECOLI (729 aa), fasta scores; opt: 782 z-score: 863.1 E(): 0, 29.8% identity in671 aa overlap. Contains Pfam match to entry ECH PF00378, Enoyl-CoA hydratase/isomerase, score 49.78. (709 aa) |
| | SCO6058 | SC9B1.05, possible hydrolase, len: 265aa; similar to hypotheticals eg. TR:P71968 (EMBL:Z80225) from Mycobacterium tuberculosis (258 aa) fasta scores; opt: 536, z-score: 585.9, E(): 2.6e-25, (44.3% identity in 235 aa overlap). Also similar to several proposed ribofavin deaminases eg. SW:RIBG_BACAM ribofavin-specific deaminase from Bacillus subtilis (371 aa) fasta scores; opt: 157, z-score: 177.0, E(): 0.015, (28.3% identity in 180 aa overlap). (265 aa) |
| | SCO6255 | SCAH10.20, possible dehydrogenase, len: 337 aa; similar to SW:STRI_STRGR (EMBL:Y00459) Stretomyces griseus streptomycin resistance protein StrI, 348 aa; fasta scores: opt: 582 z-score: 670.0 E(): 6.1e-30; 39.5% identity in 344 aa overlap and to SW:MI2D_BACSU (EMBL;M76431) Bacillus subtilis myo-inositol dehydrogenase (EC 1.1.1.18) Idh or IolG OR e83G, 330 aa; fasta scores: opt: 534 z-score: 615.6 E(): 6.5e-27; 28.8% identity in 351 aa overlap. Contains match to Pfam entry PF01408 GFO_IDH_MocA, oxidoreductase family. (337 aa) |
| | SCO6297 | Putative 3-hydroxyacyl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (318 aa) |
| | SCO6475 | SC9C7.11c, probable oxidoreductase, len: 601aa; similar to many eg. TR:Q45815 (EMBL:M31799) NAD-dependent beta-hydroxybutyryl coenzyme dehydrogenase from Clostridium acetobutylicum (282 aa) fasta scores; opt: 801, z-score: 936.4, E(): 0, (41.1% identity in 280 aa overlap). Appears to be a fusion of two dehydrogesase as each half contains Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase. (601 aa) |
| | SCO6562 | SC4B5.12c, probable oxidoreductase, len: 323; similar to several hypothetical /putative= probable 2-dehydropantoate 2-reductase from Archaeoglobus fulgidus (294 aa), fasta scores; opt: 245, z-score: 404.0, E(): 3.3e-15, (29.1% identity in 313 aa overlap). (323 aa) |
| | SCO6570 | SC3F9.05, possible oxidoreductase, len: 430 aa; similar to e.g. Zymomonas mobilisTR:P75002 (EMBL:Z80356) glucose-fructose oxidoreductase (433 aa), fasta scores; opt: 310 z-score: 305.5 E(): 8.4e-10, 27.2% identity in 426 aa overlap. (430 aa) |
| | SCO6648 | Hypothetical protein SC4G2.22; SC4G2.22, unknown, len: 112 aa. (112 aa) |
| | SCO6649 | Hypothetical protein SC4G2.23; SC4G2.23, unknown, len: 224 aa. (224 aa) |
| | SCO6658 | SC5A7.08c, probable 6-phosphogluconate dehydrogenase, len: 293 aa; similar to many eukaryotic e.g. 6PGD_BACSU 6-phosphogluconate dehydrogenase, decarboxylating (468 aa), fasta sores; opt: 445 z-score: 616.2 E(): 4.4e-27, 36.6% identity in 287 aa overlap.also highly similar to S. coelicolor 6-phosphogluconate dehydrogenase (EMBL:L27063) TR:Q53917 (291 aa), fasta sores; opt: 1654 z-score: 2054.7 E(): 0, 83.4% identity in 289 aa overlap. Contains PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature and Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogen [...] (293 aa) |
| | SCO6661 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (592 aa) |
| | SCO6670 | SC5A7.20, probable glucosidase, len: 441 aa; similar to e.g. CELF_ECOLI 6-phospho-beta-glucosidase (450 aa), fasta scores; opt: 537 z-score: 628.7 E(): 8.8e-28, 31.8% identity in 456 aa overlap. (441 aa) |
| | SCO6706 | SC4C6.16, probable glutathione-dependent aldehyde dehydrogenase, len: 396 aa; similar to many e.g. SW:FADH_METMR (EMBL:L33464), fdh, Methylobacter marinus glutathione-dependent formaldehyde dehydrogenase (424 aa), fasta scores; opt: 1126 z-score: 1211.8 E(): 0, 44.1% identity in 406 aa overlap. Similar to (EMBL:AL049485), SC6A5.31c, S.coelicolor probable zinc-binding alcohol dehydrogenase (363 aa) (31.0% identity in 316 aa overlap). Contains Pfam match to entry PF00107, adh_zinc, Zinc-binding dehydrogenases and PS00059 Zinc-containing alcohol dehydrogenases signature. (396 aa) |
| | SCO6732 | SC5F2A.15, possible fatty acid oxidative multifunctional enzyme, len: 726aa; similar to SW:FAOB_PSEFR fatty oxidation complex alpha subunit from Pseudomonas fragi (715 aa) fasta scores; opt: 1174, z-score: 1211.3, E(): 0, (33.2% identity in 717 aa overlap). Also similar to TR:O53872 (EMBL:AL022004) hypothetical protein from Mycobacterium tuberculosis (720 aa) fasta scores; opt: 3034, z-score: 3128.4, E(): 0, (64.3% identity in 717 aa overlap). Also similar to SC6A5.38 (EMBL:AL049485) possible fatty oxidation protein from Streptomyces coelicolor (733 aa) fasta scores; opt: 4069, z-score [...] (726 aa) |
| | SCO6789 | SC6A5.38, possible fatty oxidation protein, len: 733aa; similar to many eg. SW:FADB_ECOLI FadB, a multifunctional protein from the Escherichia coli fadBA operon, encoding the fatty acid-oxidizing multienzyme complex (729 aa) fasta scores; opt: 1119, z-score: 1146.7, E(): 0, (32.3% identity in 691 aa overlap). Contains Pfam matches to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family and entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase and a Prosite match to PS00923 Aspartate and glutamate racemases signature 1. (733 aa) |
| | SCO6799 | Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate.; Belongs to the zinc-containing alcohol dehydrogenase family. (342 aa) |
| | SCO6984 | Putative oxidoreductase; SC8F11.10c, possible oxidoreductase, len: 358 aa. Similar to many including: Sinorhizobium meliloti TR:O68965(EMBL:) myo-inositol dehydrogenase (EC 1.1.1.18) IdhA (330 aa), fasta scores opt: 715 z-score: 789.8 E(): 0 39.6% identity in 338 aa overlap and Streptomyces coelicolor TR:CAB60174(EMBL:AL132824) putative dehydrogenase, SCAH10.20C (337 aa), fasta scores opt: 1068 z-score: 1176.0 E(): 0 50.8% identity in 333 aa overlap. Note codon 25 offers an alternative translational start site. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (358 aa) |
| | SCO6988 | Putative oxidoreductase; SC8F11.14c, possible oxidoreductase, len: 387 aa. Similar to several including: Sinorhizobium meliloti TR:O68965(EMBL:) myo-inositol dehydrogenase (EC 1.1.1.18) IdhA (330 aa), fasta scores opt: 287 z-score: 332.8 E(): 4.2e-11 30.1% identity in 356 aa overlap and Streptomyces coelicolor TR:O69945(EMBL:AL023862) putative oxidoreductase, SC3F9.05 (430 aa), fasta scores opt: 721 z-score: 825.3 E():0 34.6% identity in 390 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (387 aa) |
| | SCO6991 | Hypothetical protein SC8F11.17; SC8F11.17, unknown, len: 68 aa. (68 aa) |
| | SCO7000 | SC8F11.26c, idh, isocitrate dehydrogenase, len: 739 aa. Shares 97.8% sequence identity with that previously sequenced and characterised: Streptomyces coelicolor isocitrate dehydrogenase Idh, 741 aa TR:Q9X5M9(EMBL:AF127018); Belongs to the monomeric-type IDH family. (739 aa) |
| | SCO7087 | Putative oxidoreductase; SC3A4.13c, possible oxidoreductase, len: 312 aa. Similar to many including: Streptomyces coelicolor TR:CAB61562(EMBL:AL133171) putative aldo/keto reductase (fragment), SCF81.28C (307 aa), fasta scores opt: 351 z-score: 407.7 E():3e-15 30.7% identity in 309 aa overlap. (312 aa) |
| | SCO7154 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa) |
| | SCO7194 | SC8A11.22, possible polysaccharide biosynthesis protein, len: 271 aa; similar to N-terminal region of SW:SPSK_BACSU (EMBL:X73124) Bacillus subtilis spore coat polysaccharide biosynthesis protein SpsK, 432 aa; fasta scores: opt: 278 z-score: 331.5 E(): 5.3e-11; 28.1% identity in 242 aa overlap. (271 aa) |
| | SCO7254 | Putative myo-inositol dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (342 aa) |
| | SCO7362 | Oxidoreductase; SC9H11.16c, oxidoreductase, len: 346 aa. Previously sequenced: Streptomyces coelicolor TR:BAA82700EMBL:AB017438) Orf3 (346 aa). Also highly similar to Corynebacterium sp. ST-10 TR:Q9ZN85(EMBL:AB020760) phenylacetaldehyde reductase (385 aa), fasta scores opt: 1382 z-score: 1438.5 E(): 0 65.2% identity in 316 aa overlap and many alcohol dehydrogenases e.g. from Sulfolobus solfataricus SW:ADH1_SULSO(EMBL:S51211) NAD-dependent alcohol dehydrogenase (EC 1.1.1.1) (347 aa), fasta scores opt: 595 z-score: 624.4 E(): 2.5e-27 32.7% identity in 355 aa overlap. Contains a Prosite h [...] (346 aa) |
| | SCO7484 | Hypothetical protein; SCBAC17A6.17c, unknown, len: 78 aa: no significant database matches. (78 aa) |
| | SCO7485 | SCBAC17A6.18c, possible oxidoreductase, len: 228aa; similar to many eg. TR:Q9L2J5 (EMBL:AL137165) putative oxidoreductase SCF42.24 from Streptomyces coelicolor (295 aa) fasta scores; opt: 450, Z-score: 508.6, 43.850% identity (45.304% ungapped) in 187 aa overlap and TR:BAB49857 (EMBL:AP003000) probable oxidoreductase from Rhizobium loti (319 aa) fasta scores; opt: 243, Z-score: 278.7, 31.980% identity (35.795% ungapped) in 197 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. (228 aa) |
| | SCO7490 | SCBAC17A6.23, possible oxidoreductase, len: 381aa; similar to many eg. TR:Q9F1Z9 (EMBL:AB033991) BtrE from Bacillus circulans (349 aa) fasta scores: opt: 710, Z-score: 676.3, 38.873% identity (41.071% ungapped) in 355 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. N-terminus rich in pro/val/ser. (381 aa) |
| | SCP1.159c | SCP1.159c, possible oxidoreductase subunit, len: 90aa; similar to the extreme C-terminus of many glycerol-3-phosphate dehydrogenases eg. SW:P37606 (GPDA_ECOLI) glycerol-3-phosphate dehydrogenase from Escherichia coli (339 aa) fasta scores; opt: 176, z-score: 239.8 E(): 6.9e-06, 39.5% identity in 76 aa overlap and TR:Q9ZBS0 (EMBL:AL034447) glycerol-3-phosphate dehydrogenase from Streptomyces coelicolor (336 aa) fasta scores; opt: 252, z-score: 338.2, E(): 2.3e-11, 53.1% identity in 81 aa overlap. Also similar to neighbouring CDS SCP1.162c fasta scores; opt: 238, z-score: 294.0, E(): 7.6 [...] (69 aa) |
| | SCP1.162c | SCP1.162c, possible oxidoreductase subunit, len: 65aa; similar to the extreme C-terminus of many glycerol-3-phosphate dehydrogenases eg. TR:Q9ZBS0 (EMBL:AL034447) glycerol-3-phosphate dehydrogenase from Streptomyces coelicolor (336 aa) fasta scores; opt: 302, z-score: 432.6, E(): 1.3e-16, 76.9% identity in 65 aa overlap. Also similar to neighbouring CDS SCP1.162c fasta scores; opt: 238, z-score: 294.0, E(): 7.6e-12, 50.7% identity in 75 aa overlap. (65 aa) |
| | mmyG | SCP1.239c, mmyG, possible oxidoreductase, len: 393aa; previously sequenced and annotated as TR:Q9JN86 (EMBL:AJ276673). Similar to many eg. TR:Q9RK99 (EMBL:AL117322) putative oxidoreductase from Streptomyces coelicolor (371 aa) fasta scores; opt: 675, z-score: 754.9, E(): 0, 36.4% identity in 357 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (393 aa) |
