(3 nodes) L-methionine salvage from S-adenosylmethionine network (Streptomyces coelicolor)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCO5431	SC6A11.07c, possible secreted nucleosidase, len: 287 aa; similar to many e.g. SW:P24247 (PFS_ECOLI) MTA/SAH nucleosidase (P46) from Escherichia coli (232 aa) fasta scores: opt: 211, z-score: 251.7, E(): 1.3e-06, 27.1% identity in 210 aa overlap. Contains Pfam match to entry PF01048 PNP_UDP_1, Phosphorylase family (which includes some nucleosidases) and possible N-terminal signal sequence. (287 aa)
	SCO3014	Putative translation initiation factor; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (380 aa)
	SCO4327	Conserved hypothetical protein SCD12A.10c; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). Does not accept aminodeoxyfutalosine (AFL) as a substrate; Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily. (209 aa)