STRINGSTRING
SCO6209 SCO6209 SCO6211 SCO6211 SCO6255 SCO6255 SCO6298 SCO6298 SCO6303 SCO6303 SCO6306 SCO6306 SCO6307 SCO6307 SCO6308 SCO6308 mmfH mmfH SCO6340 SCO6340 SCO6442 SCO6442 SCO6445 SCO6445 SCO6469 SCO6469 SCO6523 SCO6523 SCO6525 SCO6525 SCO6570 SCO6570 SCO6583 SCO6583 SCO6618 SCO6618 SCO6658 SCO6658 SCO6698 SCO6698 SCO6700 SCO6700 SCO6701 SCO6701 SCO6706 SCO6706 SCO6730 SCO6730 SCO6731 SCO6731 SCO6732 SCO6732 SCO6765 SCO6765 SCO6776 SCO6776 SCO6777 SCO6777 SCO6782 SCO6782 SCO6785 SCO6785 SCO6787 SCO6787 SCO6788 SCO6788 SCO6789 SCO6789 SCO6791 SCO6791 SCO6799 SCO6799 SCO6818 SCO6818 SCO6938 SCO6938 SCO6967 SCO6967 SCO6975 SCO6975 SCO6976 SCO6976 SCO6984 SCO6984 SCO6985 SCO6985 SCO6988 SCO6988 SCO7004 SCO7004 SCO7049 SCO7049 SCO7071 SCO7071 SCO7160 SCO7160 SCO7223 SCO7223 SCO7254 SCO7254 SCO7268 SCO7268 SCO7471 SCO7471 SCO7472 SCO7472 SCO7473 SCO7473 SCO7484 SCO7484 SCO7485 SCO7485 SCO7587 SCO7587 SCO7595 SCO7595 SCO7625 SCO7625 SCO7626 SCO7626 SCO7641 SCO7641 SCO7659 SCO7659 SCO7705 SCO7705 SCO7708 SCO7708 SCO7791 SCO7791 SCO7791a SCO7791a mmyG mmyG SCO5299 SCO5299 SCO5236 SCO5236 SCO5208 SCO5208 SCO5167 SCO5167 SCO5091 SCO5091 SCO5080 SCO5080 SCO5066 SCO5066 SCO4987 SCO4987 SCO4979 SCO4979 SCO4939 SCO4939 SCO4932 SCO4932 SCO4901 SCO4901 SCO4889 SCO4889 SCO4870 SCO4870 SCO4859 SCO4859 SCO4837 SCO4837 SCO4781 SCO4781 SCO4580 SCO4580 SCO4502 SCO4502 SCO4382 SCO4382 SCO4307 SCO4307 SCO4196 SCO4196 SCO4182 SCO4182 SCO4089 SCO4089 SCO3877 SCO3877 SCO3800 SCO3800 SCO3725 SCO3725 SCO3646 SCO3646 SCO3645 SCO3645 SCO3573 SCO3573 SCO3572 SCO3572 SCO3477 SCO3477 SCO3416 SCO3416 SCO3396 SCO3396 SCO3313 SCO3313 SCO3247 SCO3247 SCO3245 SCO3245 SCO3138 SCO3138 SCO3130 SCO3130 SCO3084 SCO3084 SCO3079 SCO3079 SCO3073 SCO3073 SCO3070 SCO3070 SCO3051 SCO3051 SCO2999 SCO2999 SCO2927 SCO2927 SCO2850 SCO2850 SCO2847 SCO2847 SCO2779 SCO2779 SCO2774 SCO2774 SCO2752 SCO2752 SCO2749 SCO2749 SCO2727 SCO2727 SCO2602 SCO2602 SCO2556 SCO2556 SCO2543 SCO2543 SCO2542 SCO2542 SCO2538 SCO2538 SCO2482 SCO2482 SCO2462 SCO2462 SCO0576 SCO0576 SCO0578 SCO0578 SCO0613 SCO0613 SCO0714 SCO0714 SCO0729 SCO0729 SCO1895 SCO1895 SCO1901 SCO1901 SCO1945 SCO1945 SCO1961 SCO1961 SCO2032 SCO2032 SCO2119 SCO2119 SCO2190 SCO2190 SCO2250 SCO2250 SCO0087 SCO0087 SCO0130 SCO0130 SCO0179 SCO0179 SCO0249 SCO0249 SCO0252 SCO0252 SCO0263 SCO0263 SCO0312 SCO0312 SCO0346 SCO0346 SCO0350 SCO0350 SCO0361 SCO0361 SCO0362 SCO0362 SCO0387 SCO0387 SCO0479 SCO0479 SCO0484 SCO0484 SCO0486 SCO0486 SCO2285 SCO2285 SCO0509 SCO0509 SCO0913 SCO0913 SCO0975 SCO0975 SCO1007 SCO1007 SCO1049 SCO1049 SCO1112 SCO1112 SCO1170 SCO1170 SCO1197 SCO1197 SCO1198 SCO1198 SCO1209 SCO1209 SCO1214 SCO1214 SCO1234 SCO1234 SCO1235 SCO1235 SCO1236 SCO1236 SCO1286 SCO1286 SCO1308 SCO1308 SCO1324 SCO1324 SCO1337 SCO1337 SCO1338 SCO1338 SCO1378 SCO1378 SCO1424 SCO1424 SCO1428 SCO1428 SCO1454 SCO1454 SCO1464 SCO1464 SCO1477 SCO1477 SCO1509 SCO1509 SCO1522 SCO1522 SCO1609 SCO1609 SCO1660 SCO1660 SCO1682 SCO1682 SCO1690 SCO1690 SCO1696 SCO1696 SCO1701 SCO1701 SCO1705 SCO1705 SCO1715 SCO1715 SCO1750 SCO1750 SCO0907 SCO0907 SCO0775 SCO0775 SCO0770 SCO0770 SCO0741 SCO0741 SCO0740 SCO0740 SCO1773 SCO1773 SCO1844 SCO1844 SCO1861 SCO1861 SCO1867 SCO1867 SCO1884 SCO1884 SCO1885 SCO1885 SCO5364 SCO5364 SCO5399 SCO5399 SCO5426 SCO5426 SCO5470 SCO5470 SCO5471 SCO5471 SCO5472 SCO5472 SCO5519 SCO5519 SCO5525 SCO5525 SCO5526 SCO5526 SCO5546 SCO5546 SCO5680 SCO5680 SCO5693 SCO5693 SCO5773 SCO5773 SCO5860 SCO5860 SCO5879 SCO5879 SCO5938 SCO5938 SCO5948 SCO5948 SCO5975 SCO5975 SCO5984 SCO5984 SCO6026 SCO6026 SCO6027 SCO6027 SCO6033 SCO6033 SCO6106 SCO6106 SCO6201 SCO6201 SCO6205 SCO6205
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
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Your Input:
SCO6209Hypothetical protein SC2G5.30; SC2G5.30, unknown, len: 191 aa; limited similarity to TR:O32141 (EMBL:Z99120) hypothetical protein from Bacillus subtilis (494 aa) fasta scores; opt: 204, z-score: 241.2,E(): 3.8e-06, (27.8% identity in 162 aa overlap). (191 aa)
SCO6211Putative uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (311 aa)
SCO6255SCAH10.20, possible dehydrogenase, len: 337 aa; similar to SW:STRI_STRGR (EMBL:Y00459) Stretomyces griseus streptomycin resistance protein StrI, 348 aa; fasta scores: opt: 582 z-score: 670.0 E(): 6.1e-30; 39.5% identity in 344 aa overlap and to SW:MI2D_BACSU (EMBL;M76431) Bacillus subtilis myo-inositol dehydrogenase (EC 1.1.1.18) Idh or IolG OR e83G, 330 aa; fasta scores: opt: 534 z-score: 615.6 E(): 6.5e-27; 28.8% identity in 351 aa overlap. Contains match to Pfam entry PF01408 GFO_IDH_MocA, oxidoreductase family. (337 aa)
SCO6298SCBAC8D1.11c, conserved hypothetical protein, len: 308 aa; similar to TR:Q9HTH7 (EMBL:AE004951) Pseudomonas aeruginosa hypothetical protein PA5387, 294 aa; fasta scores: opt: 1301 Z-score: 1431.2 bits: 272.9 E(): 3.9e-72; 64.746% identity in 295 aa overlap. (308 aa)
SCO6303Putative hydroxylase; SCIF3.05c, conserved hypothetical protein, len: 323 aa; similar to TR:Q9X4X0 (EMBL:AF119621) Pseudomonas abietaniphila hypothetical protein which C-terminus is similar to isomerase/decarboxylase, DitH, 336 aa; fasta scores: opt: 481 z-score: 532.1 E(): 4.2e-22; 38.4% identity in 310 aa overlap. Contains Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family. (323 aa)
SCO6306SCIF3.08c, possible oxidoreductase, len: 376 aa; similar to TR:AAG05975 (EMBL:AE004687) Pseudomonas aeruginosa probable FAD-dependent monooxygenase PA2587, 382 aa; fasta scores: opt: 443 z-score: 500.7 E(): 2.4e-20; 31.4% identity in 354 aa overlap. Contains Pfam match to entry PF01494 FAD_binding_3, FAD binding domain and PF01360 Monooxygenase, Monooxygenase. (376 aa)
SCO6307SCIF3.09c, putative cyclase, len: 320 aa; similar to TRNEW:AAK64254 (EMBL:AF373840) hypothetical polyketide cyclase from nicotine degradation cluster of Arthrobacter nicotinovorans Plasmid pA01 (310 aa) fasta scores; opt: 394, Z-score: 442.9, E(): 4.9e-17, 31.000% identity (32.517% ungapped) in 300 aa overlap. (320 aa)
SCO6308SCIF3.10c, possible hydrolase, len: 333 aa; similar to TR:Q9RJW4 (EMBL:AL117387) Streptomyces coelicolor putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase SCF41.05, 292 aa; fasta scores: opt: 496 z-score: 573.9 E(): 2e-24; 36.3% identity in 311 aa overlap. Contains Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family. (333 aa)
mmfHSCP1.244, mmfH, possible oxidoreductase involvedin 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis, len: 400aa; previously sequenced and annotated as hypothetical protein TR:Q9JN91 (EMBL:AJ276673). similar to many possible oxidoreductases eg. TR:O68921 (EMBL:AF058302) putative enoyl reductase, FrnT from polyketide antibiotic frenolicin biosynthetic cluster of Streptomyces roseofulvus (396 aa) fasta scores; opt: 867, z-score: 921.4, E(): 0, 48.0% identity in 329 aa overlap. (400 aa)
SCO6340SC3A7.08, unknown, len: 211 aa; similar to hypothetical proteins e.g. S. coelicolor TR:O54167 (EMBL:AL021411) SC7H1.08C (202 aa), fasta scores; opt: 243 z-score: 810.6 E(): 0, 43.8% identity in 210 aa overlap. (211 aa)
SCO6442SC9B5.09, probable alcohol dehydrogenase, len: 367aa; similar to many eg. SW:XYLB_PSEPU aryl-alcohol dehydrogenase from Pseudomonas putida (366 aa) fasta scores; opt: 928, z-score: 888.5, E(): 0, (42.6% identity in 366 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. (367 aa)
SCO6445SC9B5.12, probable inositol monophosphatase, len: 281aa; similar to many eg. SW:MYO3_LYCES myo-inositol-1(or 4)-monophosphatase 3 from Lycopersicon esculentum (tomato) (268 aa) fasta scores; opt: 286, z-score: 396.1, E(): 9e-15, (30.9% identity in 275 aa overlap). Contains PS00629 Inositol monophosphatase family signature 1 and PS00630 Inositol monophosphatase family signature 2. Contains 2x Pfam match to entry PF00459 inositol_P, Inositol monophosphatase family. (281 aa)
SCO6469SC9C7.05c, possible acyl-CoA dehydrogenase, len: 401aa; similar to many from prokaryotes and eukaryotes egs. SW:ACDB_BACSU acyl-CoA dehydrogenase from Bacillus subtilis (379 aa) fasta scores; opt: 520, z-score: 1209.6, E(): 0, (38.9% identity in 386 aa overlap) and SW:ACDM_MOUSE acyl-CoA dehydrogenase from Mus musculus (mouse) (421 aa) fasta scores; opt: 484, z-score: 1178.1, E(): 0, (40.3% identity in 390 aa overlap). Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (401 aa)
SCO6523SC5C7.08, unknown, len: 346 aa; similar to hypothetical proteins from M. tuberculosis YZ34_MYCTU MTCY31.34 (372 aa), fasta scores; opt: 678 z-score: 492.0 E(): 3.7e-20, 42.3% identity in 298 aa overlap, and to Saccharomyces cerevisiae TR:Q02883 (EMBL:U43281) LPG6P (468 aa), fasta scores; opt: 491 z-score: 495.9 E(): 2.2e-20, 35.5% identity in 262 aa overlap. (346 aa)
SCO6525SC5C7.10c, unknown, len: 255 aa; similar to hypothetical proteins from many organisms e.g. M. tuberculosis YZ34_MYCTU MTCY31.34 (372 aa), fasta scores; opt: 221 z-score: 293.2 E(): 4.4e-09, 30.7% identity in 251 aa overlap. (255 aa)
SCO6570SC3F9.05, possible oxidoreductase, len: 430 aa; similar to e.g. Zymomonas mobilisTR:P75002 (EMBL:Z80356) glucose-fructose oxidoreductase (433 aa), fasta scores; opt: 310 z-score: 305.5 E(): 8.4e-10, 27.2% identity in 426 aa overlap. (430 aa)
SCO6583Putative transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate (By similarity); Belongs to the CoA-transferase III family. Frc subfamily. (410 aa)
SCO6618Hypothetical protein SC1F2.15c; SC1F2.15c, unknown, len: 226 aa. (226 aa)
SCO6658SC5A7.08c, probable 6-phosphogluconate dehydrogenase, len: 293 aa; similar to many eukaryotic e.g. 6PGD_BACSU 6-phosphogluconate dehydrogenase, decarboxylating (468 aa), fasta sores; opt: 445 z-score: 616.2 E(): 4.4e-27, 36.6% identity in 287 aa overlap.also highly similar to S. coelicolor 6-phosphogluconate dehydrogenase (EMBL:L27063) TR:Q53917 (291 aa), fasta sores; opt: 1654 z-score: 2054.7 E(): 0, 83.4% identity in 289 aa overlap. Contains PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature and Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogen [...] (293 aa)
SCO6698SC4C6.08c, pcaB, probable 3-carboxy-cis,cis-muconate cycloisomerase, len: 454 aa; similar to e.g. SW:PCAB_BRAJA (EMBL:Y10223), pcaB, 3-carboxy-cis,cis-muconate cycloisomerase (451 aa), fasta scores; opt: 996 z-score: 1027.1 E(): 0, 43.3% identity in 448 aa overlap. Contains Pfam match to entry PF00206 lyase_1, Lyase and PS00163 Fumarate lyases signature. (454 aa)
SCO6700SC4C6.10c, pcaH, protocatechuate 3,4-dioxygenase beta subunit, len: 257 aa; highly similar to pcaH (EMBL:AF109386) Streptomyces sp. 2065 protocatechuate 3,4-dioxygenase beta subunit (257 aa), fasta scores; opt: 1686 z-score: 1951.2 E(): 0 91.1% identity in 257 aa overlap. Contains Pfam match to entry PF00775 Dioxygenase, Dioxygenase and PS00083 Intradiol ring-cleavage dioxygenases signature. (257 aa)
SCO6701SC4C6.11c, pcaF, beta-ketoadipyl-CoA thiolase, len: 400 aa; highly similar to pcaF (EMBL:AF117893) Streptomyces sp. 2065 beta-ketoadipyl-CoA thiolase (400 aa), fasta scores; opt: 2314 z-score: 2497.6 E(): 0, 87.4% identity in 397 aa overlap. Highly similar others from S.coelicolor e.g. (EMBL:AL049587), SC5F2A.14, S.coelicolor probable thiolase (404 aa) (40.2% identity in 423 aa overlap). Contains Pfam match to entry PF00108 thiolase, Thiolase, PS00099 Thiolases active site, PS00098 Thiolases acyl-enzyme intermediate signature and PS00737 Thiolases signature 2; Belongs to the thiolase-l [...] (400 aa)
SCO6706SC4C6.16, probable glutathione-dependent aldehyde dehydrogenase, len: 396 aa; similar to many e.g. SW:FADH_METMR (EMBL:L33464), fdh, Methylobacter marinus glutathione-dependent formaldehyde dehydrogenase (424 aa), fasta scores; opt: 1126 z-score: 1211.8 E(): 0, 44.1% identity in 406 aa overlap. Similar to (EMBL:AL049485), SC6A5.31c, S.coelicolor probable zinc-binding alcohol dehydrogenase (363 aa) (31.0% identity in 316 aa overlap). Contains Pfam match to entry PF00107, adh_zinc, Zinc-binding dehydrogenases and PS00059 Zinc-containing alcohol dehydrogenases signature. (396 aa)
SCO6730SC5F2A.13, possible racemase, len: 398aa; similar to many egs. TR:O06543 (EMBL:Z95584) hypothetical protein from Mycobacterium tuberculosis (360 aa) fasta scores; opt: 1338, z-score: 1408.4, E(): 0, (57.1% identity in 361 aa overlap) and TR:O09176 (EMBL:U89906) alpha-methylacyl-CoA racemase from Mus musculus (moues) (361 aa) fasta scores; opt: 953, z-score: 1005.2, E(): 0, (44.2% identity in 344 aa overlap). Also similar to SC6A5.34 (EMBL:AL049485) probable fatty acid co-A racemase from Streptomyces coelicolor (387 aa) fasta scores; opt: 1787, z-score: 1558.9, E(): 0, (69.9% identity i [...] (398 aa)
SCO6731SC5F2A.14, probable thiolase, len: 404aa; similar to many egs. TR:O53871 (EMBL:AL022004) putative beta-ketoadypyl coA tiolase from Mycobacterium tuberculosis (403 aa) fasta scores; opt: 1842, z-score: 1989.2, E(): 0, (67.6% identity in 404 aa overlap) and TR:O53017 (EMBL:X97452) acetyl coA thiolase from Escherichia coli (401 aa) fasta scores; opt: 819, z-score: 887.9, E(): 0, (41.7% identity in 424 aa overlap). Also similar to SC6A5.37 (EMBL:AL049485) probable acetyl coA acetyltransferase from Streptomyces coelicolor (404 aa) fasta scores; opt: 2480, z-score: 2352.6, E(): 0, (95.0% ide [...] (404 aa)
SCO6732SC5F2A.15, possible fatty acid oxidative multifunctional enzyme, len: 726aa; similar to SW:FAOB_PSEFR fatty oxidation complex alpha subunit from Pseudomonas fragi (715 aa) fasta scores; opt: 1174, z-score: 1211.3, E(): 0, (33.2% identity in 717 aa overlap). Also similar to TR:O53872 (EMBL:AL022004) hypothetical protein from Mycobacterium tuberculosis (720 aa) fasta scores; opt: 3034, z-score: 3128.4, E(): 0, (64.3% identity in 717 aa overlap). Also similar to SC6A5.38 (EMBL:AL049485) possible fatty oxidation protein from Streptomyces coelicolor (733 aa) fasta scores; opt: 4069, z-score [...] (726 aa)
SCO6765SC6A5.14, possible lipoprotein, len: 213 aa; similar to SW:TYRT_STRLN proposed tyrosinase co-factor from the melanin biosynthesis in Streptomyces lincolnensis (140 aa) fasta scores; opt: 115, z-score: 142.8, E(): 1.2, (29.2% identity in 120 aa overlap). Contains Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (213 aa)
SCO6776Conserved hypothetical protein; SC6A5.25, unknown, len: 370 aa; similar to SW:YZ34_MYCTU hypothetical protein from Mycobacterium tuberculosis (372 aa) fasta scores; opt: 1125, z-score: 1301.0, E(): 0, (51.3% identity in 335 aa overlap). Contains Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop). (370 aa)
SCO6777SC6A5.26c, possible beta-lactamase, len: 310 aa; similar to SW:BLA1_XANMA L1 metallo-beta-lactamase from Xanthomonas maltophilia (290 aa) fasta scores; opt: 161, z-score: 198.8, E(): 0.0009, (25.5% identity in 247 aa overlap). (310 aa)
SCO6782SC6A5.31c, probable zinc-binding alcohol dehydrogenase, len: 363aa; similar to many eg. TR:Q59096 (EMBL:U61983) benzyl alcohol dehydrogenase from Acinetobacter calcoaceticus (371 aa) fasta scores; opt: 948, z-score: 937.8, E(): 0, (42.8% identity in 360 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite match to PS00059 Zinc-containing alcohol dehydrogenases signature. (363 aa)
SCO6785SC6A5.34, probable fatty acid co-A racemase, len: 387aa; similar to egs. TR:O06543 (EMBL:Z95584) hypothetical protein from Mycobacterium tuberculosis (360 aa) fasta scores; opt: 1304, z-score: 1373.1, E(): 0, (52.8% identity in 362 aa overlap) and TR:O09176 (EMBL:U89905) alpha-methylacyl-CoA racemase from rat liver (Rattus norvegicus) (361 aa) fasta scores; opt: 985, z-score: 1039.0, E(): 0, (44.4% identity in 342 aa overlap); Belongs to the CoA-transferase III family. (387 aa)
SCO6787SC6A5.36, acdH3, probable acyl-CoA dehydrogenase, len: 382 aa; similar to many (prokaryote and eukaryote) egs. TR:O33229 (EMBL:Z98209) probable acyl-CoA dehydrogenase from Mycobacterium tuberculosis (386 aa) fasta scores; opt: 1583, z-score: 1842.1, E(): 0, (62.7% identity in 378 aa overlap) and SW:ACDL_HUMAN acyl-CoA dehydrogenase from Homo sapiens (Human) (430 aa) fasta scores; opt: 1265, z-score: 1472.3, E(): 0, (51.8% identity in 380 aa overlap). Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and Prosite matches to PS00072 Acyl-CoA dehydrogenases signature [...] (382 aa)
SCO6788SC6A5.37, probable acetyl coA acetyltransferase (thiolase), len: 404aa; similar to many eg. TR:O53017 (EMBL:X97452) acetyl coA acetyltransferase (thiolase) from Escherichia coli (401 aa) fasta scores; opt: 831, z-score: 891.0, E(): 0, (41.9% identity in 422 aa overlap). Contains Pfam match to entry PF00108 thiolase, Thiolase and Prosite matches to PS00737 Thiolases signature 2 and PS00099 Thiolases active site; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
SCO6789SC6A5.38, possible fatty oxidation protein, len: 733aa; similar to many eg. SW:FADB_ECOLI FadB, a multifunctional protein from the Escherichia coli fadBA operon, encoding the fatty acid-oxidizing multienzyme complex (729 aa) fasta scores; opt: 1119, z-score: 1146.7, E(): 0, (32.3% identity in 691 aa overlap). Contains Pfam matches to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family and entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase and a Prosite match to PS00923 Aspartate and glutamate racemases signature 1. (733 aa)
SCO6791SC6A5.40c, partial CDS, probable acyl-coA dehydrogenase, len: 395aa; similar to many eg. TR:O34421 (EMBL:Z99113) from Bacillus subtilis (380 aa) fasta scores; opt: 777, z-score: 903.0, E(): 0, (36.6% identity in 383 aa overlap) and SW:ACDS_HUMAN acyl-coA dehydrogenase from Homo sapiens (Human) (412 aa) fasta scores; opt: 643, z-score: 747.6, E(): 0, (32.3% identity in 387 aa overlap). Contains three Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and a Prosite match to PS00072 Acyl-CoA dehydrogenases signature 1. (379 aa)
SCO6799Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate.; Belongs to the zinc-containing alcohol dehydrogenase family. (342 aa)
SCO6818Putative phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
SCO6938SC1G8.10c, probable acyl-CoA dehydrogenase, len: 417 aa. Similar to Bacillus subtilis TR:ACDB_BACSU (EMBL:U29084) acyl-CoA dehydrogenase (EC 1.3.99.-) MmgC (379 aa), fasta scores opt: 651 z-score: 737.5 E(): 0 31.1% identity in 380 aa overlap and Streptomyces coelicolor TR:CAB87216 (EMBL:AL163641) acyl-CoA dehydrogenase, SCC105.10 (386 aa), fasta scores opt: 575 z-score: 651.8 E(): 7.6e-29 31.7% identity in 382 aa overlap. Contains a Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and contains possible membrane spanning hydrophobic domains. (417 aa)
SCO6967SC6F7.20, pcaF, beta-ketoadipyl-CoA thiolase, len: 395 aa. Highly similar to many including: Pseudomonas putida SW:PCAF_PSEPU(EMBL:U10895) beta-ketoadipyl CoA thiolase (EC 2.3.1.-) (400 aa), fasta scores opt: 1352 z-score: 1491.2 E(): 0 53.9% identity in 399 aa overlap and Streptomyces coelicolor TR:Q9XAM9(EMBL:AL079355) beta-ketoadipyl-CoA thiolase, SC4C6.11C (400 aa), fasta scores opt: 1450 z-score: 1598.9 E(): 0 56.9% identity in 401 aa overlap. Contains a Pfam match to entry PF00108 thiolase, Thiolase and Prosite hits to PS00098 Thiolases acyl-enzyme intermediate signature, PS00737 [...] (395 aa)
SCO6975Putative acetolactate synthase; SC8F11.01c, possible amino acid synthase, partial CDS, len: > 237 aa. Similar to several enzymes requiring TPP as a cofactor including: Spirulina platensis SW:ILVB_SPIPL(EMBL:M75907) acetolactate synthase (EC 4.1.3.18) IlvY (579 aa), fasta scores opt: 166 z-score: 195.5 E(): 0.0019 27.7% identity in 238 aa overlap. Also highly similar, in parts, to the Bacillus subtilis SW:IOLD_BACSU(EMBL:D14399) hypothetical protein, IolD found within the inositol utilisation operon (580 aa), fasta scores opt: 577 z-score: 669.1 E(): 7.7e-30 47.2% identity in 178 aa ove [...] (624 aa)
SCO6976Conserved hypothetical protein; SC8F11.02c, unknown, len: 298 aa. Similar to the Bacillus subtilis SW:IOLB_BACSU(EMBL:D14399) hypothetical protein, IolB, found within the inositol utilisation operon (271 aa), fasta scores opt: 443 z-score: 516.6 E(): 2.4e-21 34.9% identity in 281 aa overlap. (298 aa)
SCO6984Putative oxidoreductase; SC8F11.10c, possible oxidoreductase, len: 358 aa. Similar to many including: Sinorhizobium meliloti TR:O68965(EMBL:) myo-inositol dehydrogenase (EC 1.1.1.18) IdhA (330 aa), fasta scores opt: 715 z-score: 789.8 E(): 0 39.6% identity in 338 aa overlap and Streptomyces coelicolor TR:CAB60174(EMBL:AL132824) putative dehydrogenase, SCAH10.20C (337 aa), fasta scores opt: 1068 z-score: 1176.0 E(): 0 50.8% identity in 333 aa overlap. Note codon 25 offers an alternative translational start site. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (358 aa)
SCO6985Hypothetical protein SC8F11.11c; SC8F11.11c, unknown, len: 387 aa. (387 aa)
SCO6988Putative oxidoreductase; SC8F11.14c, possible oxidoreductase, len: 387 aa. Similar to several including: Sinorhizobium meliloti TR:O68965(EMBL:) myo-inositol dehydrogenase (EC 1.1.1.18) IdhA (330 aa), fasta scores opt: 287 z-score: 332.8 E(): 4.2e-11 30.1% identity in 356 aa overlap and Streptomyces coelicolor TR:O69945(EMBL:AL023862) putative oxidoreductase, SC3F9.05 (430 aa), fasta scores opt: 721 z-score: 825.3 E():0 34.6% identity in 390 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (387 aa)
SCO7004SC8F11.30, probable carbohydrate kinase,len: 479 aa. Highly similar to many e.g. Bacillus subtilis SW:GLPK_BACSU(EMBL:M34393) glycerol kinase (EC 2.7.1.30), GlpK (496 aa), fasta scores opt: 688 z-score: 766.4 E():0 35.1% identity in 496 aa overlap. Contains a Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases. (479 aa)
SCO7049SC4G1.15, probable glutaminase, len: 307 aa; similar to TR:O87405 (EMBL:AF057158) Rhizobium etli glutaminase A, 309 aa; fasta scores: opt: 990 z-score: 1158.2 E(): 0; 52.3% identity in 304 aa overlap and to middle part of SW:GLSK_RAT (EMBL:M65150) Rattus norvegicus glutaminase, kidney isoform precursor (EC 3.5.1.2) GlsK, 647 aa; fasta scores: opt: 577 z-score: 672.7 E(): 5.3e-30; 35.2% identity in 293 aa overlap; Belongs to the glutaminase family. (307 aa)
SCO7071SC4G1.37c, conserved hypothetical protein, len: 130 aa; similar to TR:Q9RZR3 (EMBL:AE001826) Deinococcus radiodurans conserved hypothetical protein DRB0052, 133 aa; fasta scores: opt: 250 z-score: 278.2 E(): 5e-08; 42.2% identity in 135 aa overlap. (130 aa)
SCO7160SC9A4.22c, conserved hypothetical protein, len: 277 aa; similar to TR:Q9RJW0 (EMBL:AL117387) Streptomyces coelicolor hypothetical 31.6 kDa protein SCF41.09, 294 aa; fasta scores: opt: 504 z-score: 582.4 E(): 5.7e-25; 38.1% identity in 281 aa overlap. (277 aa)
SCO7223Putative monooxygenase; SC2H12.22, possible monooxygenase, len: 373 aa. Similar to many other monooxygenases e.g. Sphingomonas sp. TR:P96555(EMBL:AB000564) salicylate hydroxylase (395 aa), fasta scores opt: 347 z-score: 390.9 E(): 2.7e-14 27.0% identity in 378 aa overlap and Streptomyces coelicolor TR:Q9RK22(EMBL:AL109974) putative monooxygenase, SCF34.03C (388 aa), fasta scores opt: 998 z-score: 1113.7 E():0 47.2% identity in 343 aa overlap. Contains a Pfam match to entry PF01360 Monooxygenase, Monooxygenase. (373 aa)
SCO7254Putative myo-inositol dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (342 aa)
SCO7268SC5H1.24c, add, probable adenosine deaminase, len: 359 aa; similar to many e.g. SW:ADD_ECOLI (EMBL:M59033), Add, Escherichia coli adenosine deaminase (333 aa), fasta scores; opt: 369 z-score: 434.3 E(): 7.2e-17, 32.8% identity in 338 aa overlap. Weakly similar to TR:O86737 (EMBL:AL031035) S.coelicolor possible adenosine deaminase (387 aa) (28.9% identity in 342 aa overlap). Contains Pfam match to entry PF00962 A_deaminase, Adenosine/AMP deaminase, score 220.40, E-value 2.6e-62; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deami [...] (359 aa)
SCO7471SCBAC17A6.04, possible phenylacetic acid degradation protein PaaA, len: 328 aa: similar to many e.g. SW:P76077 (PAAA_ECOLI) phenylacetic acid degradation protein PaaA from Escherichia coli (309 aa) fasta scores; opt: 1540, Z-score: 1801.2, 69.967% identity (69.967% ungapped) in 303 aa overlap. (328 aa)
SCO7472SCBAC17A6.05, possible phenylacetic acid degradation protein PaaB, len: 103 aa: similar to many e.g. SW:P76078 (PAAB_ECOLI) phenylacetic acid degradation protein PaaB from Escherichia coli (95 aa) fasta scores; opt: 427, Z-score: 565.4, 66.667% identity (66.667% ungapped) in 90 aa overlap. (103 aa)
SCO7473SCBAC17A6.06, possible phenylacetic acid degradation protein PaaC, len: 275 aa: similar to many e.g. SW:P76079 (PAAC_ECOLI) phenylacetic acid degradation protein PaaC from Escherichia coli (248 aa) fasta scores; opt: 470, Z-score: 547.8, 41.057% identity (44.105% ungapped) in 246 aa overlap. (275 aa)
SCO7484Hypothetical protein; SCBAC17A6.17c, unknown, len: 78 aa: no significant database matches. (78 aa)
SCO7485SCBAC17A6.18c, possible oxidoreductase, len: 228aa; similar to many eg. TR:Q9L2J5 (EMBL:AL137165) putative oxidoreductase SCF42.24 from Streptomyces coelicolor (295 aa) fasta scores; opt: 450, Z-score: 508.6, 43.850% identity (45.304% ungapped) in 187 aa overlap and TR:BAB49857 (EMBL:AP003000) probable oxidoreductase from Rhizobium loti (319 aa) fasta scores; opt: 243, Z-score: 278.7, 31.980% identity (35.795% ungapped) in 197 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. (228 aa)
SCO7587SC5F1.41, possible integral membrane protein, len: 455 aa; similar to TR:Q9L0X9 (EMBL:AL159178) Streptomyces coelicolor putative membrane protein SCH22A.03c, 429 aa; fasta scores: opt: 1974 z-score: 2163.7 E(): 0; 69.7% identity in 423 aa overlap. Contains possible hydrophobic membrane spanning regions. (455 aa)
SCO7595Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (391 aa)
SCO7625SC2H2.23, probable monooxygenase, len: 373 aa; similar to SW:TETX_BACFR (EMBL:M37699) Bacteroides fragilis tetracycline resistance protein TetX, 388 aa; fasta scores: opt: 598 z-score: 663.7 E(): 2e-29; 31.3% identity in 367 aa overlap. Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase. (373 aa)
SCO7626SC2H2.24c, probable monooxygenase, len: 492 aa; similar to SW:MHPA_ECOLI (EMBL:D86239) Escherichia coli 3-(3-hydroxy-phenyl)propionate hydroxylase (EC 1.14.13.-) MhpA, 554 aa; fasta scores: opt: 521 z-score: 602.2 E(): 5.2e-26; 32.6% identity in 356 aa overlap. Contains Pfam matches to entries PF01494 FAD_binding_3, FAD binding domain and PF01360 Monooxygenase, Monooxygenase. (492 aa)
SCO7641SC10F4.14, possible dehydrogenase, len: 398 aa; similar to many other Streptomyces coelicolor putative dehydrogenases, e.g. TR:Q9RD04 (EMBL:AL133422) putative dehydrogenase SCM1.40c, 296 aa; fasta scores: opt: 352 z-score: 383.2 E(): 8.2e-14; 33.5% identity in 260 aa overlap. (398 aa)
SCO7659SC10F4.32c, probable oxidoreductase, len: 373 aa; similar to SW:TETX_BACFR (EMBL:M37699) Bacteroides fragilis tetracycline resistance protein TetX, 388 aa; fasta scores: opt: 524 z-score: 576.3 E(): 1.4e-24; 30.2% identity in 374 aa overlap and to TR:CAB94636 (EMBL:AL359215) Streptomyces coelicolor hypothetical protein SC2H12.22, 373 aa; fasta scores: opt: 1709 z-score: 1482.3 E(): 0; 71.2% identity in 375 aa overlap. Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase. (373 aa)
SCO7705SCBAC12C8.06, possible oxidoreductase, len: 396aa: similar to many eg. SW:Q01911 (TETX_BACFR) tetracycline resistance oxidoreductase from Bacteroides fragilis (388 aa) fasta scores; opt: 612, Z-score: 673.8, 31.818% identity (33.427% ungapped) in 374 aa overlap and TR:Q9F3M8 (EMBL:AL450350) putative oxidoreductase SC10F4.32c from Streptomyces coelicolor (373 aa) fasta scores; opt: 1391, Z-score: 1524.2, 59.116% identity (60.795% ungapped) in 362 aa overlap. Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase. (396 aa)
SCO7708SCBAC12C8.09c, conserved hypothetical protein, len: 216aa: similar to many eg. TR:O86609 (EMBL:AL031155) hypothetical protein from Streptomyces coelicolor (211 aa) fasta scores; opt: 764, Z-score: 865.8, 54.673% identity (55.981% ungapped) in 214 aa overlap. (216 aa)
SCO7791SC5E9.38c, possible secreted oxidoreductase, len: 401 aa; similar to many e.g. TR:O53772 (EMBL:AL021942) putative oxidoreductase from Mycobacterium tuberculosis (388 aa) fasta scores; opt: 524, z-score: 584.4, E(): 4.4e-25, 32.4% identity in 373 aa overlap. Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase. (401 aa)
SCO7791aSC10B8A.01c, possible secreted oxidoreductase, len: 409 aa; similar to TR:O53772 (EMBL:AL021942) putative oxidoreductase from Mycobacterium tuberculosis (388 aa) fasta scores; opt: 305, z-score: 305.8, E(): 1.5e-09, 31.6% identity in 358 aa overlap. Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase. (409 aa)
mmyGSCP1.239c, mmyG, possible oxidoreductase, len: 393aa; previously sequenced and annotated as TR:Q9JN86 (EMBL:AJ276673). Similar to many eg. TR:Q9RK99 (EMBL:AL117322) putative oxidoreductase from Streptomyces coelicolor (371 aa) fasta scores; opt: 675, z-score: 754.9, E(): 0, 36.4% identity in 357 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (393 aa)
SCO5299SC6G9.34, possible membrane protein, len: 312 aa; unknown function, similar to proteins from Mycobacterium leprae and Mycobacterium tuberculosis e.g. TR:O33063 (EMBL:Z99494) Mycobacterium leprae hypothetical protein (341 aa), fasta scores; opt: 316 z-score: 387.1 E(): 3.1e-14, 27.1% identity in 255 aa overlap (divergent at C-terminus). Contains hydrophobic, possible membrane-spanning region. (312 aa)
SCO5236Putative glucosamine phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (261 aa)
SCO5208Putative monophosphatase; Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine. (266 aa)
SCO5167SCP8.30, conserved hypothetical protein, len: 260 aa; similar to TR:O05856 (EMBL:Z95120) Mycobacterium tuberculosis hypothetical 25.1 kD protein MTCY07D11.16, 231 aa; fasta scores: opt: 599 z-score: 647.2 E(): 1.4e-28; 42.5% identity in 233 aa overlap. Contains 4x degenerate repeat:T(G/A)G. (260 aa)
SCO5091Cyclase; SCBAC28G1.17, actIV, cyclase, len: 297 aa; identical to previously sequenced TR:Q02057 (EMBL:X63449) Streptomyces coelicolor dehydrogenase ActI ORF5, 297 aa. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily. (297 aa)
SCO5080Putative hydrolase; SCBAC28G1.06, actVA5, possible hydrolase, len: 381 aa; identical to previously sequenced TR:Q53907 (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes of the actinorhodin biosynthetic gene cluster, ActVA5, 381 aa and similar to TR:Q9F0J3 (EMBL:AF218066) Streptomyces arenae hydrolase NcnH, 405 aa; fasta scores: opt: 1391 Z-score: 1521.5 bits: 290.3 E(): 3.9e-77; 56.522% identity in 368 aa overlap. (381 aa)
SCO5066SCBAC20F6.09, possible beta-lactamase, len: 304 aa; similar to TR:Q9X7X2 (EMBL:AL049485) Streptomyces coelicolor putative beta-lactamase SC6E5.26c, 310 aa; fasta scores: opt: 598 Z-score: 696.3 bits: 136.9 E(): 3.4e-31; 53.115% identity in 305 aa overlap and to SW:BLA1_XANMA (EMBL:X75074) Xanthomonas maltophilia metallo-beta-lactamase L1 precursor (beta-lactamase, type II) (EC 3.5.2.6), 290 aa; fasta scores: opt: 146 Z-score: 175.9 bits: 40.6 E(): 0.033; 25.952% identity in 289 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily and match to [...] (304 aa)
SCO49872SCK36.10c, possible D-amino acid deaminase, len: 433 aa; similar to TR:Q45085 (EMBL:AF158699) Burkholderia cepacia D-serine deaminase Dsd, 432 aa; fasta scores: opt: 919 Z-score: 1026.2 bits: 199.0 E(): 1.5e-49; 41.259% identity in 429 aa overlap. Contains match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop). (433 aa)
SCO4979Putative phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (609 aa)
SCO4939Hypothetical protein SCK31.31c; SCK13.31c, unknown, len: 260 aa. (260 aa)
SCO4932SCK13.24, hutH, histidine ammonia-lyase, len: 512 aa; highly similar to SW:HUTH_STRGR (EMBL:M77841) Streptomyces griseus histidine ammonia-lyase (EC 4.3.1.3) HutH, 516 aa; fasta scores: opt: 2928 z-score: 3294.6 E(): 0; 88.5% identity in 513 aa overlap. Contains Pfam match to entry PF00221 PAL, Phenylalanine and histidine ammonia-lyases and matches to Prosite entries PS00217 Sugar transport proteins signature 2 and PS00488 Phenylalanine and histidine ammonia-lyases signature; Belongs to the PAL/histidase family. (512 aa)
SCO49012SCK8.27, probable adenosine deaminase, len: 396 aa; similar to SW:ADD_ECOLI (EMBL:M59033) Escherichia coli adenosine deaminase (EC 3.5.4.4) Add, 333 aa; fasta scores: opt: 421 z-score: 505.2 E(): 1.4e-20; 32.2% identity in 338 aa overlap and to TR:Q9X7T2 (EMBL:AL049863) Streptomyces coelicolor putative adenosine deaminase SC5H1.24c, 359 aa; fasta scores: opt: 1373 z-score: 1637.4 E(): 0; 60.7% identity in 351 aa overlap. Contains Pfam match to entry PF00962 A_deaminase, Adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases famil [...] (396 aa)
SCO48892SCK8.15, probable cytidine deaminase, len: 130 aa; similar to SW:CDD_HUMAN (EMBL:L27943) Homo sapiens cytidine deaminase (EC 3.5.4.5) Cda or Cdd, 146 aa; fasta scores: opt: 297 z-score: 380.0 E(): 1.3e-13; 36.2% identity in 130 aa overlap and to TR:53367 (EMBL:AL021841) Mycobacterium tuberculosis cytidine deaminase Cdd or MTV016.15c, 133 aa; fasta scores: opt: 518 z-score: 652.9 E(): 8.4e-29; 61.1% identity in 126 aa overlap. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region and match to Prosite entry PS00903 Cytidine and de [...] (130 aa)
SCO4870SCK20.11c, probable monooxygenase, len: 483 aa; similar to TR:P95598 (EMBL:U56415) Corynebacterium equii rifampin monooxygenase Iri, 479 aa; fasta scores: opt: 691 z-score: 714.1 E(): 3.1e-32; 35.0% identity in 488 aa overlap and to TR:O86481 (EMBL:AJ007932) Streptomyces argillaceus oxygenase MtmOII, 531 aa; fasta scores: opt: 590 z-score: 609.9 E(): 1.9e-26; 33.3% identity in 520 aa overlap. Contains Pfam match to entry PF01494 FAD_binding_3, FAD binding domain and match PF01360 Monooxygenase, Monooxygenase. (483 aa)
SCO4859Hypothetical protein; SC5G8.27c, unknown, len: 183 aa; similar to TR:Q9Z593 (EMBL:AL035478) hypothetical protein from Streptomyces coelicolor (191 aa) fasta scores; opt: 164, z-score: 195.7, E(): 0.0019, 32.6% identity in 187 aa overlap. (183 aa)
SCO4837Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (481 aa)
SCO4781SCD63.13, possible cholesterol oxidase, len: 602 aa; similar to TR:Q59530 (EMBL:U00015) Mycobacterium leprae probable cholesterol oxidase precursor (EC 1.1.3.6) ChoD, 585 aa; fasta scores: opt: 1114 z-score: 1181.0 E(): 0; 60.5% identity in 583 aa overlapand to SW:CHOD_BREST (EMBL:D00712) Brevibacterium sterolicum cholesterol oxidase precursor (EC 1.1.3.6) ChoD, 552 aa; fasta scores: opt: 228 z-score: 244.5 E(): 3.4e-06; 26.9% identity in 576 aa overlap. (602 aa)
SCO4580SCD16A.03, probable fumarylacetoacetase, len: 418aa; similar to several from eukaryotes eg. SW:FAAA_HUMAN fumarylacetoacetase from human (419 aa) fasta scores; opt: 1192, z-score: 1370.0, E(): 0, (44.6% identity in 426 aa overlap). (418 aa)
SCO4502SCD35.09, probable ketoacyl CoA thiolase, len: 428 aa; similar to TR:O86361 (EMBL:AL021929) Mycobacterium tuberculosis FadA2, 440 aa; fasta scores: opt: 1585 z-score: 1791.9 E(): 0; 63.0% identity in 446 aa overlap and to SW:THIK_ECOLI (EMBL:M87049) Escherichia coli 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (fatty oxidation complex beta subunit) (beta-ketothiolase) (acetyl-CoA acyltransferase) FadA, 387 aa; fasta scores: opt: 453 z-score: 515.8 E(): 2.7e-21; 30.9% identity in 430 aa overlap. Contains Pfam match to entry PF00108 thiolase, Thiolase; Belongs to the thiolase-like superfamily. [...] (428 aa)
SCO4382SCD10.14, probable acyl CoA dehydrogenase, len: 382 aa; similar to SW:ACDB_MYCTU (EMBL:Z79700) Mycobacterium tuberculosis probable acyl CoA dehydrogenase MTCY10D7.02, 388 aa; fasta scores: opt: 1694 z-score: 1964.7 E(): 0; 64.3% identity in 387 aa overlap. Contains 2 Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (382 aa)
SCO4307Conserved hypothetical protein SCD95A.40c; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (311 aa)
SCO41962SCD46.10c, possible organophosphate acid anhydrase, len: 404aa; similar to TR:Q50432 (EMBL:M91040) organophosphate acid anhydrase from Mycobacterium sp. (409 aa) fasta scores; opt: 762, z-score: 836.3, E(): 0, 44.8% identity in 402 aa overlap and TR:Q9S1C6 (EMBL:AB007293) organophosphorus insecticide hydrolase from Arthrobacter sp. (415 aa) fasta scores; opt: 705, z-score: 774.0, E(): 0, 42.6% identity in 408 aa overlap. (404 aa)
SCO4182Conserved hypothetical protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (141 aa)
SCO4089Valine dehydrogenase (EC 1.4.1.-); Oxidative deamination of branched-chain amino acids. Oxidizes L-valine and L-alpha-aminobutyric acid efficiently, and L-isoleucine and L-leucine less efficiently. Does not act on D-valine. The catabolism of L-valine is the major source of fatty acid precursors for macrolide biosynthesis and a vital source of antibiotic precursors. Uses NAD; no activity was found with NADP. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (364 aa)
SCO3877SCH18.14c, probable 6-phosphogluconate dehydrogenase, len: 291 aa; identical to previously sequenced TR:Q53917 (EMBL:L27063) Streptomyces coelicolor 6-phosphogluconate dehydrogenase, 291 aa and highly similar to TR:O88014 (EMBL:AL031107) S. coelicolor SC5A7.08c probable 6-phosphogluconate dehydrogenase, 293 aa; fasta scores: opt: 1654 z-score: 1688.1 E(): 0; 83.4% identity in 289 aa overlap. Contains Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogenasesand match to Prosite entry. (291 aa)
SCO3800SCGD3.01, possible acyl-CoA dehydrogenase, partial CDS, len: >491 aa; weakly similar to TR:P97088 (EMBL:Z92974), bcd, Clostridium thermosaccharolyticum butyryl-CoA dehydrogenase (379 aa), fasta scores; opt: 176 z-score: 203.7 E(): 0.00051, 28.0% identity in 318 aa overlap. Also highly similar to putative acyl-CoA dehydrogenases from mycobacteria e.g. TR:O69506 (EMBL:AL022486) Mycobacterium leprae probable acyl-CoA dehydrogenase (611 aa) (64.3% identity in 493 aa overlap). Contains two Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase; SCAC2.08, possible dehydrogenase (f [...] (608 aa)
SCO3725SCH22A.03c, possible membrane protein, len: 429 aa. similar to TR:Q9F388 (EMBL:AL450165) from Streptomyces coelicolor. Contains possible hydrophobic membrane spanning regions. (429 aa)
SCO3646Putative oxidoreductase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (271 aa)
SCO3645Putative hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (410 aa)
SCO3573SCH17.07c, hypothetical protein, len: 312 aa; unknown function, similar to TR:O53287 (EMBL:AL021287) Mycobacterium tuberculosis hypothetical protein (288 aa), fasta scores; opt: 648 z-score: 739.5 E(): 0, 50.0% identity in 260 aa overlap. Weakly similar to TR:O05487 (EMBL:M93187), TnpA, Arthrobacter sp. plasmid pASU1 transposase (229 aa) (25.4% identity in 256 aa overlap). (312 aa)
SCO3572SCH17.06c, possible hydrolase, len: 256 aa; weakly similar to eukaryotic glyoxalase e.g. SW:GL2M_ARATH (EMBL:U90928), glx2-1, Arabidopsis thaliana hydroxyacylglutathione hydrolase (331 aa), fasta scores; opt: 186 z-score: 218.1 E(): 8e-05, 29.2% identity in 161 aa overlap. Similar to many hypothetical proteins e.g. TR:O69645 (EMBL:AL022121) Mycobacterium tuberculosis putative hydrolase (264 aa) (54.7% identity in 247 aa overlap). (256 aa)
SCO3477SCE65.13c, possible dehydrogenase, len: 344 aa; similar to TR:CAB50292 (EMBL:AJ248287) Pyrococcus abyssi threonine 3-dehydrogenase (EC 1.1.1.103) 348 aa; fasta scores: opt: 567 z-score: 616.8 E(): 5.6e-27; 33.8% identity in 328 aa overlap and to SW:TDH_BACSU (EMBL:Z99112) threonine 3-dehydrogenase (EC 1.1.103) Tdh, 347 aa; fasta scores: opt: 544 z-score: 592.1 E(): 1.3e-25; 31.4% identity in 331 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. (344 aa)
SCO3416SCE9.23, gad, probable glutamate decarboxylase, len: 475 aa; similar to many e.g. SW:DCEA_ECOLI (EMBL:M84024), gadA, Escherichia coli glutamate decarboxylase alpha (466 aa), fasta scores; opt: 1433 z-score: 1665.2 E(): 0, 50.0% identity in 426 aa overlap. Contains Pfam match to entry PF00282 pyridoxal_deC, Pyridoxal-dependent decarboxylase conserved domain, score 276.70, E-value 1.1e-79; Belongs to the group II decarboxylase family. (475 aa)
SCO3396SCE9.03c, possible membrane protein, len: 370 aa; unknown function, similar to SW:YLI2_CORGL (EMBL:X60312) Corynebacterium glutamicum hypothetical protein (426 aa), fasta scores; opt: 274 z-score: 307.1 E(): 8.8e-10, 23.9% identity in 351 aa overlap and TR:P94973 (EMBL:Z85982) Mycobacterium tuberculosis hypothetical protein (489 aa) (23.1% identity in 386 aa overlap). Contains hydrophobic regions at N-terminus, possibly a membrane anchor. (377 aa)
SCO3313SCE68.11c, conserved hypothetical protein, len: 305 aa; unknown function, N-terminal half similar to hypothetical proteins from Mycobacterium tuberculosis, Mycobacterium paratuberculosis and Streptomyces lividans, e.g. SW:Y08L_MYCTU (EMBL:Z77137) Mycobacterium tuberculosis hypothetical protein (149 aa), fasta scores; opt: 297 z-score: 354.1 E(): 2.1e-12, 42.7% identity in 124 aa overlap. (305 aa)
SCO3247SCE29.16c, possible acyl CoA oxidase, len: 600 aa; similar to many acyl CoA oxidases, especially from eukaryotes e.g. SW:CAOP_RAT acyl CoA oxidase from Rattus norvegicus (rat) (661 aa) fasta scores; opt: 462, z-score: 477.6, E(): 2.7e-19, (27.8% identity in 425 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). (600 aa)
SCO3245SCE29.14c, possible salicylate hydroxylase (putative secreted protein), len: 420 aa; similar to many e.g. TR:P96555 (EMBL:AB000564) salicylate hydroxylase from Sphingomonas sp. AJ1 (395 aa) fasta scores; opt: 830, z-score: 827.2, E(): 0, (41.9% identity in 320 aa overlap) and TR:G4104775 (EMBL:AF039534) salicylate hydroxylase from Pseudomonas stutzeri strain AN10 (389 aa) fasta scores; opt: 707, z-score: 706.0, E(): 5.1e-32, (34.7% identity in 401 aa overlap). Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase, score 91.00, E-value 2.4e-23. Contains possible N-terminal r [...] (420 aa)
SCO3138SCE66.17c, galT, galactose-1-phosphate uridylyltransferase (EC 2.7.7.10), len: 353aa; similar to many especially SW:P13212 (GAL7_STRLI) galactose-1-phosphate uridylyltransferase from Streptomyces lividans (354 aa) fasta scores; opt: 1998, z-score: 2363.0, E(): 0, 87.2% identity in 352 aa overlap. Contains Pfam match to entry PF01087 GalP_UDP_transf, Galactose-1-phosphate uridyl transferase and Prosite match to PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. (353 aa)
SCO3130SCE66.09, possible dehydratase, len: 391 aa; similar to many e.g. SW:P31572 (CAIB_ECOLI) L-carnitine dehydratase from Escherichia coli (405 aa) fasta scores; opt: 440, z-score: 478.4, E(): 3.6e-19, 28.7% identity in 401 aa overlap; Belongs to the CoA-transferase III family. (391 aa)
SCO3084SCE25.25c, pobA, p-hydroxybenzoate hydroxylase, len: 389 aa; highly similar to SW:PHHY_PSEAE (EMBL:M23173) Pseudomonas aeruginosa p-hydroxybenzoate hydroxylase (EC 1.14.13.2) (4-hydroxybenzoate 3-monooxygenase) (PhbH) PobA, 394 aa; fasta scores: opt: 1334 z-score: 1559.4 E(): 0; 50.9% identity in 389 aa overlap and to TR:Q06519 (EMBL:L13747) Pseudomonas fluorescens p-hydroxybenzoate hydroxylase (EC 1.14.13.2) (4-hydroxybenzoate 3-monooxygenase), 397 aa; fasta scores: opt: 1395 z-score: 1630.5 E(): 0; 54.5% identity in 389 aa overlap. Contains Pfam matches to entries PF01494 FAD_binding [...] (389 aa)
SCO3079SCE25.20, probable thiolase, len: 406 aa; similar to SW:CATF_ACICA (EMBL:AF009224) Acinetobacter calcoaceticus beta-ketoadipyl CoA thiolase (EC 2.3.1.-) CatF, 401 aa; fasta scores: opt: 957 z-score: 1066.1 E(): 0; 40.0% identity in 415 aa overlap and to TR:CAB45575 (EMBL:AL079355) Streptomyces coelicolor PcaF, beta-ketoadipyl CoA thiolase SC4C6.11c, 400 aa; fasta scores: opt: 895 z-score: 916.7 E(): 0; 38.9% identity in 409 aa overlap. Contains Pfam match to entry PF00108 thiolase, Thiolase and match to Prosite entry PS00737 Thiolases signature 2; Belongs to the thiolase-like superfami [...] (406 aa)
SCO3073Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (572 aa)
SCO3070SCE25.11c, probable chlorohydrolase, len: 391 aa; similar to SW:HUTI_BACSU (EMBL:D31856) Bacillus subtilis imidazolonepropionase (EC 3.5.2.7) (imidazolone-5-propionate hydrolase) HutI, 421 aa; fasta scores: opt: 659 z-score: 767.1 E(): 0; 36.1% identity in 404 aa overlap. Contains Pfam match to entry PF01685 ATZ_TRZ, Chlorohydrolase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (391 aa)
SCO3051SCBAC19G2.06c, fadE, acyl-CoA dehydrogenase, len: 385 aa: similar to many e.g. TR:Q9RIQ5 (EMBL:AJ250495) fatty acid acyl CoA dehydrogenase FadE from Streptomyces lividans (385 aa) fasta scores; opt: 2480, Z-score: 2753.5, 99.740% identity (99.740% ungapped) in 385 aa overlap and SW:P45867 (ACDA_BACSU) acyl CoA dehydrogenase from Bacillus subtilis (379 aa) fasta scores; opt: 1214, Z-score: 1351.1, 53.600% identity (54.472% ungapped) in 375 aa overlap. Also similar to TR:Q9RKY7 (EMBL:AL133213) SC6D7.11 Acd acyl CoA dehydrogenase from Streptomyces coelicolor (391 aa) fasta scores; opt: 10 [...] (385 aa)
SCO2999SCE33.01c, hypothetical protein (fragment), len: >187 aa; similar to TR:Q9X7B2 (EMBL:AL049913) Mycobacterium leprae hypothetical 177.9 kD protein MCLB1610.10, 1622 aa; fasta scores: opt: 154 z-score: 172.5 E(): 0.038; 29.7% identity in 155 aa overlap; SCE99.06c, conserved hypothetical protein (fragment), len: >1515 aa; similar to TR:AAG06456 (EMBL:AE004731) Pseudomonas aeruginosa conserved hypothetical protein PA3068, 1620 aa; fasta scores: opt: 4170 z-score: 4589.7 E(): 0; 46.3% identity in 1521 aa overlap. (1653 aa)
SCO2927SCE19A.27c, probable 4-hydroxyphenylpyruvate dioxygenase, len: 381 aa; highly similar to many e.g. SW:HPPD_STRAW (EMBL:U11864) Streptomyces avermitilis 4-hydroxyphenylpyruvate dioxygenase (380 aa), fasta scores; opt: 2347 z-score: 2634.5 E(): 0, 91.9% identity in 381 aa overlap. Similar to TR:Q9Z4X7 (EMBL:AL035640) S. coelicolor probable 4-hydroxyphenylpyruvic acid dioxygenase (325 aa) (36.4% identity in 330 aa overlap); Belongs to the 4HPPD family. (381 aa)
SCO2850Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; SCE20.24c, possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, len: 285 aa. Similar to many including: Mycobacterium tuberculosis TR:O53242 (EMBL:AL021287) possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (239 aa), fasta scores opt: 544 z-score: 651.1 E(): 7e-29 40.3% identity in 221 aa overlap and similar in parts to the C-terminus of Escherichia coli SW:HPCE_ECOLI (EMBL:X75028) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) (405 aa), fasta scores opt: 467 z-score: 556.6 E(): 1.3e-23 40.2% identity in 214 aa [...] (285 aa)
SCO2847Putative oxidoreductase; SCE20.21, possible oxidoreductase, len: 360 aa. Similar to several other putative oxidoreductases e.g. Escherichia coli SW:YDGJ_ECOLI(EMBL:AE000258) hypothetical oxidoreductase (346 aa), fasta scores opt: 873 z-score: 972.9 E():0 45.0% identity in 353 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (360 aa)
SCO2779SCC105.10, acdH, acyl-CoA dehydrogenase, len: 386 aa; identical to previously sequenced TR:Q9XCG6 (EMBL:AF142581) Streptomyces coelicolor acyl-CoA dehydrogenase AcdH, 386 aa. Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and matches to Prosite entries PS00072 Acyl-CoA dehydrogenases signature 1 and PS00073 Acyl-CoA dehydrogenases signature 2. (386 aa)
SCO2774SCC105.05c, acdH2, probable acyl-CoA dehydrogenase, len: 385 aa; similar to TR:Q9X7Y2 (EMBL:AL049485) Streptomyces coelicolor probable acyl-CoA dehydrogenase SC6A5.36, 382 aa; fasta scores: opt: 1170 z-score: 1351.4 E(): 0; 47.9% identity in 382 aa overlap. Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and match to Prosite entry PS00073 Acyl-CoA dehydrogenases signature 2. (385 aa)
SCO2752SCC57A.23c, possible oxidoreductase, len: 378 aa. Weakly similar to several other putative oxidoreductases e.g. Streptomyces coelicolor TR:O69945 (EMBL:AL023862) putative oxidoreductase (430 aa), fasta scores opt: 252 z-score: 300.4 E(): 2.4e-09 28.8% identity in 278 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (378 aa)
SCO2749Carbohydrate transport protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (129 aa)
SCO2727Hypothetical protein SCC46.12c; SCC46.12c, improbable CDS predicted by HMM, len: 125 aa. (125 aa)
SCO2602Hypothetical protein SCC88.13c; SCC88.13c, unknown, len: 707 aa. (707 aa)
SCO2556Conserved hypothetical protein SCC77.23; SCC77.23, unknown, len: 247 aa. Similar to Mycobacterium tuberculosis TR:O07720(EMBL:Z97193) hypothetical 26.9 KD protein (250 aa), fasta scores opt: 618 z-score: 666.7 E(): 9.6e-30 45.0% identity in 238 aa overlap. (247 aa)
SCO2543SCC77.10c, possible dihydrodipicolinate synthase. len: 322 aa. Similar to many dihydrodipicolinate synthases including: Bacillus subtilis SW:DAPA_BACSU (EMBL:L08471) dihydrodipicolinate synthase (EC 4.2.1.52) (290 aa), fasta scores opt: 341 z-score: 396.9 E(): 1e-14 26.8% identity in 284 aa overlap and Streptomyces coelicolor TR:Q9X9X7 (EMBL:AL096743) putative dihydropicolinate synthase SCI7.13C (316 aa), fasta scores opt: 927 z-score: 1065.7 E():0 53.1% identity in 294 aa overlap. Contains a Pfam match to entry PF00701 DHDPS; Belongs to the DapA family. (322 aa)
SCO2542Putative glucarate dehydratase; Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D- glucarate (5-kdGluc).; Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. (431 aa)
SCO2538Hypothetical protein SCC77.05; SCC77.05, unknown, len: 132 aa. Similar to Mycobacterium tuberculosis TR:O05833(EMBL:Z95208) hypothetical 11.1 KD protein (113 aa), fasta scores opt: 254 z-score: 298.3 E(): 3.2e-09 53.1% identity in 96 aa overlap and Mycobacterium leprae TR:Q49767(EMBL:U00016) hypothetical 11.1 KD protein (108 aa), fasta scores opt: 186 z-score: 224.0 E(): 4.4e-05 39.4% identity in 99 aa overlap. (132 aa)
SCO2482SC7A8.21, possible dehydrogenase (putative secreted protein), len: 311 aa; similar to various hypothetical dehydrogenases, e.g. TR:Q9YE14 (EMBL:AP000060) Aeropyrum pernix 287 aa long hypothetical 3-hydroxyisobutyrate dehydrogenase APE0756, 287 aa; fasta scores: opt: 196 z-score: 223.5 E(): 4.7e-05; 27.0% identity in 293 aa overlap. Contains possible N-terminal region signal peptide sequence. (311 aa)
SCO2462SC7A8.01, probable sugar kinase (fragment), len: >434 aa; similar to TR:CAB61582 (EMBL:AL133210) Streptomyces coelicolor xylulose kinase (fragment) XylB, 432 aa; fasta scores: opt: 822 z-score: 871.9 E(): 0; 38.8% identity in 418 aa overlap and to SW:XYLB_STRRU (EMBL:M73789) Streptomyces rubiginosus xylulose kinase (EC 2.7.1.17) XylB, 481 aa; fasta scores: opt: 814 z-score: 862.8 E(): 0; 39.5% identity in 423 aa overlap. Contains Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases and PS00445 FGGY family of carbohydrate kinases signature 2; SCC24.33, probable sugar ki [...] (482 aa)
SCO0576SC5G5.08c, possible oxidoreductase, len: 291 aa; low similarity to many ketol-acid reductoisomerases, e.g. SW:ILVC_METTH (EMBL:AE000905) Methanobacterium thermoautotrophicum ketol-acid reductoisomerase (EC 1.1.1.86) IlvC or MTH1442, 333 aa; fasta scores: opt: 159 Z-score: 188.7 bits: 43.1 E(): 0.0065; 25.301% identity in 166 aa overlap. (291 aa)
SCO0578SCF55.02c, possible triosephosphate isomerase, len: 259 aa; similar to SW:TPIS_MYCTU (EMBL:Z95844) Mycobacterium tuberculosis triosephosphate isomerase (EC 5.3.1.1) TpiA, 261 aa; fasta scores: opt: 437 z-score: 490.8 E(): 5.8e-20; 38.9% identity in 221 aa overlap. Contains match to Pfam entry PF00121 TIM, Triosephosphate isomerase. (259 aa)
SCO0613SCF55.37, arcA, arginine deiminase, len: 420 aa; similar to SW:ARCA_PSEAE (EMBL:X14694) Pseudomonas aeruginosa arginine deiminase (EC 3.5.3.6) ArcA, 417 aa; fasta scores: opt: 1807 z-score: 2137.4 E(): 0; 61.7% identity in 412 aa overlap. (420 aa)
SCO0714SCF42.24, possible oxidoreductase, len: 295 aa. Identical to the previously sequenced Streptomyces coelicolor TR:Q9ZIW7 (EMBL:AF009336) Orf1 (fragment) (>195 aa). Also weakly similar to Sinorhizobium meliloti TR:O68965 (EMBL:AF059313) myo-inositol dehydrogenase (EC 1.1.1.18) (330 aa), fasta scores opt: 242 z-score: 275.5 E(): 5.9e-08 26.5% identity in 302 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (295 aa)
SCO07293SC5B7.07, conserved hypothetical protein, len: 140 aa; similar to TR:O27449 (EMBL:AE000902) Methanobacterium thermoautotrophicum conserved protein MTH1398, 133 aa; fasta scores: opt: 122 z-score: 167.4 E(): 0.085; 26.7% identity in 116 aa overlap. (140 aa)
SCO1895SCI7.13c, probable dihydropicolinate synthase, len: 316 aa; similar to many egs. SW:KDGD_PSEPU 5-dehydro-4-deoxyglutarate dehydratase from Pseudomonas putida (303 aa) fasta scores; opt: 731, z-score: 838.6, E(): 0, (41.1% identity in 302 aa overlap) and SW:DAPA_BACSU dihydropicolinate synthase from Bacillus subtilis (290 aa) fasta scores; opt: 374, z-score: 432.9, E(): 8.8e-17, (29.2% identity in 288 aa overlap). Contains Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate synthetase family. (316 aa)
SCO1901SCI7.19, probable zinc-binding dehydrogenase, len: 329 aa; similar to many e.g. SW:DHSO_BACSU sorbitol dehydrogenase from Bacillus subtilis (352 aa) fasta scores; opt: 552, z-score: 626.6, E(): 1.4e-27, (30.1% identity in 345 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite match to PS00059 Zinc-containing alcohol dehydrogenases signature. (329 aa)
SCO1945Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P). (258 aa)
SCO1961Dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. (157 aa)
SCO2032Hypothetical protein; SC4G6.01, partial CDS, unknown, len: >35 aa; SC3A3.10, hypothetical protein, len: 404 aa; unknown function, similar to both bacterial dehydratases e.g. SW:CAIB_ECOLI (EMBL:X67748) Escherichia coli L-carnitine dehydratase (405 aa), fasta scores; opt: 579 z-score: 647.7 E(): 1e-28, 28.9% identity in 409 aa overlap and to eukaryotic isomerases e.g. TR:O43673 (EMBL:AF047020) Homo sapiens alpha-methylacyl-CoA racemase (382 aa) (31.2% identity in 398 aa overlap). Similar to others from S.coelicolor e.g. SC5F2A.13 (EMBL:AL049587) S.coelicolor possible racemase (398 aa) ( [...] (404 aa)
SCO21196-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (342 aa)
SCO2190Conserved hypothetical protein; SC5F7.11, unknown, len: 369aa; similar to SW:Y00R_MYCTU hypothetical protein from Mycobacterium tuberculosis (301 aa) fasta scores; opt: 885, z-score: 925.1, E(): 0, (46.9% identity in 290 aa overlap). (369 aa)
SCO2250Hypothetical protein SC1G2.12; SC1G2.12, unknown, len: 275 aa. Weakly similar to a protein of undefined function from Mycobacterium tuberculosis TR:O07720(EMBL:Z97193) hypothetical 26.9 KD protein (250 aa), fasta scores 0pt: 176 z-score: 214.1 E(): 0.00015 28.4% identity in 250 aa overlap. (275 aa)
SCO0087SCJ11.16c, putative secreted protein, len: 349 aa; similar to TR:P97061 (EMBL:Z81324) hypothetical protein downstream of a beta-lactam regulatory protein in Streptomyces clavuligerus (338 aa) fasta scores; opt: 548, z-score: 613.6, E(): 8.1e-27, (40.6% identity in 330 aa overlap). (349 aa)
SCO0130SCJ21.11, possible beta-lactamase, len; 304 aa; some similarity to S. coelicolor TR:CAB39710 (EMBL:AL049485) putative beta-lactamase SC6A5.26C (310 aa), fasta scores; opt: 197 z-score: 236.5 E(): 8e-06, 28.1% identity in 295 aa overlap, and TR:O34760 (EMBL:AF008220) Bacillus subtilis YtnP (256 aa), fasta scores; opt: 189 z-score: 228.5 E(): 2.2e-05, 25.1% identity in 191 aa overlap and similar to TR:Q9ALW1 (EMBL:AF338729) Plesiomonas sp. M6 methyl parathion hydrolase Mpd, 331 aa; fasta scores: opt: 511 Z-score: 578.8 bits: 115.3 E(): 1.3e-24; 31.61% identity in 310 aa overlap. (304 aa)
SCO0179SCJ1.28c,possible zinc-containing dehydrogenase, len: 356 aa. Similar to many including: Thermoanaerobacter brockii SW:ADH_THEBR (EMBL; X64841) NADP-dependent alcohol dehydrogenase (EC 1.1.1.2) (352 aa), fasta scores opt: 556 z-score: 601.1 E(): 4e-26 33.7% identity in 338 aa overlap and Halobacterium volcanii TR:O34179 (EMBL; U95372) dehydrogenase (389 aa), fasta scores opt: 715 z-score: 770.1 E(): 0 37.0% identity in 351 aa overlap. Contains a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and a PS00059 Zinc-containing alcohol dehydrogenases signature. (356 aa)
SCO0249SCJ9A.28c, possible monooxygenase, len: 504 aa; similar to many e.g. TR:Q9ZGM8 (EMBL:AF077869) oxygenase involved in the last step of mithramycin biosynthesis in Streptomyces argillaceus (533 aa) fasta scores; opt: 1215, z-score: 1311.5, E(): 0, (45.0% identity in 513 aa overlap). Contains Pfam matches to entry PF01360 Monooxygenase, Monooxygenase and Pfam match to entry PF01494 FAD_binding_3, and Prosite match to PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains possible uncleavable N-terminal signal sequence. (504 aa)
SCO0252SCJ9A.31c, possible oxidoreductase, len: 415 aa; similar to many e.g. TR:AAD25066 (EMBL:AF121000) tetracycline resistance associated oxidoreductase homolog from Corynebacterium glutamicum (402 aa) fasta scores; opt: 672, z-score: 786.6, E(): 0, (32.8% identity in 390 aa overlap) and SW:TETX_BACFR tetracycline resistance oxidoreductase from Bacteroides fragilis transposons (388 aa) fasta scores; opt: 275, z-score: 324.5, E(): 1e-10, (24.9% identity in 377 aa overlap). Contains Pfam match to entry PF01360 Monooxygenase, Monooxygenase. (415 aa)
SCO0263SCF1.05c, possible oxidoreductase, len: 371 aa; weakly similar to many e.g. TR:O69945 (EMBL:AL023862) putative oxidoreductase from Streptomyces coelicolor (430 aa) fasta scores; opt: 224, z-score: 247.7, E(): 2e-06, (26.0% identity in 392 aa overlap). Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (371 aa)
SCO0312SC5G9.21, probable acyl-CoA dehydrogenase, len: 389 aa; similar to both bacterial and eukaryotic acyl-CoA dehydrogenases e.g. SW:ACDS_HUMAN (EMBL:M26393), AcaDS, Homo sapiens mitochondrial acyl-CoA dehydrogenase short-chain specific precursor (412 aa), fasta scores; opt: 653 z-score: 771.4 E(): 0, 34.8% identity in 376 aa overlap. Also similar to SCI30A.22C (EMBL:AL096811) Streptomyces coelicolor probable acyl-CoA dehydrogenase. Contains 2 Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (389 aa)
SCO0346SCF41.05, possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, len: 292 aa. Similar to many e.g. Mycobacterium leprae TR:O33119 (EMBL; Z99263) possible 2-hydroxyhepta-2, 4-diene-1,7- dioate isomerase (242 aa), fasta scores opt: 491 z-score: 566.1 E(): 3.5e-24 40.6% identity in 212 aa overlap, Streptomyces coelicolor TR:O86527 (EMBL; AL031124) hypothetical 28.2 KD protein SC1C2.27 (261 aa), fasta scores opt: 465 z-score: 479.6 E(): 1.9e-21 40.0% identity in 220 aa overlap and to the C-terminus of Escherichia coli SW:HPCE_ECOLI (EMBL; X75028) homoprotocatechuate catabolism bifunctiona [...] (292 aa)
SCO0350Conserved hypothetical protein; SCF41.09, unknown, len: 334 aa. Similar to several hypotheticals including: Rhizobium sp. SW:Y4MH_RHISN (EMBL; AE000085) hypothetical 33.9 KD protein Y4MH (297 aa), fasta scores opt: 262 z-score: 309.5 E(): 6.9e-10 23.8% identity in 303 aa overlap. (294 aa)
SCO0361Conserved hypothetical protein SCF41.20c; SCF41.20c, unknown, len: 390 aa. Highly similar, over available sequence, to Caulobacter crescentus TR: Q46022 (EMBL; X98879) xylX gene (fragment) (>140 aa), fasta scores opt: 276 z-score: 326.5 E(): 7.8e-11 50.0% identity in 122 aa overlap. (390 aa)
SCO0362SCF41.21, possible racemase, len: 403 aa. Weakly similar to Eukaryotic and Prokaryotic racemases e.g. Homo sapiens (Human) TR:O43673 (EMBL; AF047020) alpha-methylacyl-CoA racemase (EC 5.1.99.4) (382 aa), fasta scores opt: 466 z-score: 544.7 E(): 5.5e-23 31.1% identity in 392 aa overlap and Streptomyces coelicolor TR:CAB40680 (EMBL; AL049587) putative racemase SC5F2A.13 (398 aa), fasta scores opt: 508 z-score: 593.2 E(): 1.1e-25 34.5% identity in 383 aa overlap; Belongs to the CoA-transferase III family. (403 aa)
SCO0387SCF62.13. possible bi-domain oxidoreductase, len: 726 aa. The N-terminus is similar to many Zinc-binding dehydrogenases e.g. Sinorhizobium meliloti TR:O31186 (EMBL; AF031940) alcohol dehydrogenase (340 aa), fasta scores pt: 224 z-score: 241.8 E(): 4.1e-06 25.5% identity in 333 aa overlap. The C-terminus is similar to other oxidoreductases e.g. Zymomonas mobilis SW:GFO_ZYMMO (EMBL; M97379) glucose-fructose oxidoreductase precursor (EC 1.1.99.28) (439 aa), fasta scores opt: 243 z-score: 260.3 E(): 3.8e-07 26.1% identity in 272 aa overlap. Note this CDS is also weakly similar to the C-ter [...] (726 aa)
SCO0479SCF76.19c, putative phosphatase, len: 274 aa. Almost identical to Streptomyces lividans TR:O70034 (EMBL; AJ223365) Sbl1 gene (274 aa), fasta scores opt: 1764 z-score: 2005.4 E():0 97.1% identity in 274 aa overlap. Also weakly similar to many inositol monophosphatases e.g. Mycobacterium smegmatis TR:O51845 (EMBL; AF005905) inositol monophosphate phosphatase (276 aa), fasta scores opt: 299 z-score: 346.7 E(): 6e-12 33.1% identity in 269 aa overlap and Escherichia coli SW: SUHB_ECOLI (EMBL; M34828) extragenic suppressor protein SuhB (267 aa), fasta scores opt: 269 z-score: 313.0 E(): 4.6e [...] (274 aa)
SCO0484SCF34.03c, possible monooxygenase, len: 388 aa; similar to SW:TETX_BACFR (EMBL:M37699), TetX, Bacteroides fragilis tetracycline resistance protein from transposon Tn4351/Tn4400 (388 aa), fasta scores; opt: 582 z-score: 637.6 E(): 3.7e-28, 33.9% identity in 351 aa overlap. Also similar to monooxygenases e.g. TR:P96555 (EMBL:AB000564) Sphingomonas sp. salicylate hydroxylase (395 aa) (27.2% identity in 360 aa overlap). Similar to others from S.coelicolor e.g. TR:Q9Z4Y6 (EMBL:AL035707) S.coelicolor possible salicylate hydroxylase (420 aa) (32.9% identity in 340 aa overlap). Contains Pfam m [...] (388 aa)
SCO0486SCF34.05c, possible monooxygenase, len: 407 aa; similar to TR:Q9ZI64 (EMBL:AF039534), NahW, Pseudomonas stutzeri salicylate hydroxylase (389 aa), fasta scores; opt: 328 z-score: 383.8 E(): 5.1e-14, 27.0% identity in 403 aa overlap and to the N-terminal half of some epoxidases e.g. SW:ABA2_LYCES (EMBL:Z83835) Lycopersicon esculentum zeaxanthin epoxidase precursor (669 aa) (26.8% identity in 336 aa overlap). Also similar to many putative oxidoreductases e.g. TR:O54177 (EMBL:AL021411) Streptomyces coelicolor possible oxidoreductase (397 aa) (56.1% identity in 403 aa overlap). Contains Pfa [...] (407 aa)
SCO2285SCC75A.31, possible oxidoreductase, len: 351 aa. Similar to many Eukaryotic dimeric dihydrodiol dehydrogenases e.g. Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) TR:BAA83489(EMBL:AB021932) dimeric dihydrodiol dehydrogenase (EC 1.3.1.20) (334 aa), fasta scores opt: 741 z-score: 868.2 E():0 39.1% identity in 335 aa overlap. Also similar to Prokaryotic oxidoreductases e.g. Streptomyces antibioticus TR:AAD55450(EMBL:AF055579) putative 3-ketoreductase (328 aa), fasta scores opt: 434 z-score: 510.8 E(): 4.5e-21 34.0% identity in 300 aa overlap. Contains a Pfam match to entry [...] (351 aa)
SCO0509Glycerol kinase 2 (ATP:glycerol 3-phosphotransferase) (EC 2.7.1.30); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (507 aa)
SCO0913Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (323 aa)
SCO09756-phosphogluconate 1-dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
SCO10072SCG2.20c, possible oxidoreductase, len: 380 aa; similar to TR:O54177 (EMBL:AL021411) Streptomyces coelicolor putative oxidoreductase SC7H1.18, 397 aa; fasta scores: opt: 842 z-score: 944.5 E(): 0; 41.6% identity in 368 aa overlap. Contains Pfam matches to entries PF01494 FAD_binding_3, FAD binding domain and PF01360 Monooxygenase, Monooxygenase. (380 aa)
SCO1049SCG20A.29c, probable secreted oxidoreductase, len: 387 aa; similar to SW:GFO_ZYMMO (EMBL:M97379) Zymomonas mobilis glucose-fructose oxidoreductase precursor (EC 1.1.99.28) Gfo, 439 aa; fasta scores: opt: 287 z-score: 318.4 E(): 2.9e-10; 26.6% identity in 350 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family and possible N-terminal region signal peptide sequence. (387 aa)
SCO11122SCG38.05, probable oxidoreductase, len: 567 aa; similar to SW:AIDB_ECOLI (EMBL:L20915) Escherichia coli putative acyl-CoA dehydrogenase; adaptive response AidB protein, 541 aa; fasta scores: opt: 1437 z-score: 1553.6 E(): 0; 45.8% identity in 517 aa overlap. Contains 2x Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and match to Prosite entry PS00073 Acyl-CoA dehydrogenases signature 2. (567 aa)
SCO1170Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family. (481 aa)
SCO1197SCG11A.28c, possible acyl-CoA dehydrogenase, len:362 aa; low similarity to TR:AAD44195 (EMBL:AF142581) Streptomyces coelicolor acyl-CoA dehydrogenase AcdH, 386 aa; fasta scores: opt: 266 z-score: 294.1 E(): 5.2e-09; 28.3% identity in 392 aa overlap and to SW:ACDS_CLOAB (EMBL:U17110) Clostridium acetobutylicum acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2) (ScaD) (butyryl-CoA dehydrogenase) Bcd, 379 aa; fasta scores: opt: 231 z-score: 256.5 E(): 6.5e-07; 26.5% identity in 378 aa overlap. Contains two matches to Pfam entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (362 aa)
SCO1198SCG11A.29c, probable acyl-CoA dehydrogenase, len:393 aa; similar to TR:Q54857 (EMBL:) Streptomyces purpurascens acyl-CoA dehydrogenase FamB (fragment), 288 aa; fasta scores: opt: 1195 z-score: 1377.5 E(): 0; 83.2% identity in 208 aa overlap and to SW:ACD_MYCLE (EMBL:U00012) Mycobacterium leprae acyl-CoA dehydrogenase (EC 1.3.99.-) Acd or B1308_F1_34, 389 aa; fasta scores: opt: 386 z-score: 447.1 E(): 1.6e-17; 28.5% identity in 376 aa overlap. Contains two matches to Pfam entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (393 aa)
SCO12092SCG58.09c, probable acyl-CoA dehydrogenase, len: 408 aa; similar to SW:ACDA_BACSU (EMBL:Z49782) Bacillus subtilis acyl-CoA dehydrogenase (EC 1.3.99.-) AcdA, 379 aa; fasta scores: opt: 512 z-score: 587.6 E(): 2.9e-25; 41.3% identity in 400 aa overlap. Contains 2x Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and match to Prosite entry PS00073 Acyl-CoA dehydrogenases signature 2. (408 aa)
SCO12146-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (341 aa)
SCO12342SCG1.09c, ureC, urease alpha subunit, len: 573 aa; similar to SW:URE1_MYCTU (EMBL:L41141) Mycobacterium tuberculosis urease alpha subunit (EC 3.5.1.5) UreC, 577 aa; fasta scores: opt: 2744 z-score: 2925.3 E(): 0; 67.8% identity in 577 aa overlap and to TR:CAA19974 (EMBL:AL031124) Streptomyces coelicolor putative urease alpha subunit SC1C2.07, 558 aa; fasta scores: opt: 1483 z-score: 1444.2 E(): 0; 46.1% identity in 570 aa overlap. Contains Pfam match to entry PF00449 urease, Urease and match to Prosite entry PS01120 Urease nickel ligands signature and PS00145 Urease active site; Belon [...] (573 aa)
SCO12352SCG1.10c, ureB, urease beta subunit, len: 103 aa; similar to SW:URE2_RHIME (EMBL:S69145) Rhizobium meliloti urease beta subunit UreB (EC 3.5.1.5), 101 aa; fasta scores: opt: 400 z-score: 525.2 E(): 8.7e-22; 59.8% identity in 102 aa overlap. Contains Pfam match to entry PF00699 Urease_beta, Urease beta subunit. (103 aa)
SCO12362SCG1.11c, ureA, urease gamma subunit, len: 100 aa; similar to SW:URE3_MYCTU (EMBL:L41141) Mycobacterium tuberculosis urease gamma subunit (EC 3.5.1.5) UreA, 100 aa; fasta scores: opt: 498 z-score: 638.4 E(): 4.3e-28; 71.7% identity in 99 aa overlap. Contains Pfam match to entry PF00547 urease_gamma, Urease, gamma subunit. (100 aa)
SCO12862SCG18.33, probable oxidoreductase, len: 374 aa; similar to TR:P96072 (EMBL:U76606) Streptomyces viridifaciens isobutylamine N-hydroxylase (EC 1.14.-.-) (IBAH) VlmH, 378 aa; fasta scores: opt: 1020 z-score: 1177.8 E(): 0; 45.9% identity in 379 aa overlap. (374 aa)
SCO1308SCBAC36F5.19, probable hydrolase, len: 407 aa; similar to SW:PHHY_PSEFL (EMBL:X68438) Pseudomonas fluorescens P-hydroxybenzoate hydroxylase (EC 1.14.13.2) PobA, 394 aa; fasta scores: opt: 907 Z-score: 1007.6 bits: 195.3 E(): 1.6e-48; 39.018% identity in 387 aa overlap. Contains Pfam matches to entries PF01494 FAD_binding_3, FAD binding domain and PF01360 Monooxygenase, Monooxygenase. (407 aa)
SCO13242SCG61.06c, possible 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase, len: 389 aa; similar to many e.g. SW:P21151 (THIK_ECOLI) 3-ketoacyl-CoA thiolase (EC 2.3.1.16)from Escherichia coli (387 aa) fasta scores; opt: 892, z-score: 980.9, E(): 0, 42.7% identity in 403 aa overlap and SW:P54810 (THIL_PARDE) acetyl-CoA acetyltransferase (EC 2.3.1.9) from Paracoccus denitrificans (391 aa) fasta scores; opt: 892, z-score: 980.9, E(): 0, 41.7% identity in 403 aa overlap. Contains Pfam match to entry PF00108 thiolase, Thiolase and Prosite match to PS00737 Thiolases signature 2; Belongs to th [...] (389 aa)
SCO13372SCG61.19c, possible oxidoreductase, len: 301 aa; similar to SW:P37168 (MVIM_SALTY) virulence factor MviM from Salmonella typhimurium (307 aa) fasta scores; opt: 467, z-score: 533.5, E(): 3.1e-22, 33.9% identity in 304 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (301 aa)
SCO13382SCG61.20c, possible monooxygenase (putative secreted protein), len: 396 aa; similar to many eg. TR:Q9Z4Y6 (EMBL:AL035707) putative salicylate hydroxylase from Streptomyces coelicolor (420 aa) fasta scores; opt: 505, z-score: 556.8, E(): 1.5e-23, 34.8% identity in 391 aa overlap and TR:Q9ZSN7 (EMBL:AF098947) CTF2B from Arabidopsis thaliana (Mouse-ear cress) (428 aa) fasta scores; opt: 464, z-score: 511.9, E(): 4.9e-21, 30.8% identity in 383 aa overlap. Contains Pfam match to entry PF01494 FAD_binding_3, FAD binding domain and Pfam match to entry PF01360 Monooxygenase, Monooxygenase. Co [...] (396 aa)
SCO1378Putative glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
SCO1424Conserved hypothetical protein SC6D7.15; SC6D7.15, unknown, len: 536 aa. Highly similar to a protein of undefined function from Mycobacterium tuberculosis TR:O53494(EMBL:AL021899) hypothetical 55.9 KD protein (534 aa), fasta scores opt: 1708 z-score: 1846.6 E():0 53.7% identity in 534 aa overlap. (536 aa)
SCO1428SC6D7.11, acd, acyl-CoA dehydrogenase (EC 1.3.99.-), len: 391 aa. Highly similar to many Prokaryotic and eukaryotic acyl-CoA dehydrogenases including: Megasphaera elsdenii SW:ACDS_MEGEL(EMBL:L04528) acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2) (383 aa), fasta scores opt: 926 z-score: 1026.2 E():0 40.9% identity in 372 aa overlap and Homo sapiens (Human) SW:ACDS_HUMAN(EMBL:M26393) acyl-CoA dehydrogenase, short-chain precursor (EC 1.3.99.2) (412 aa, fasta scores opt: 924 z-score: 1023.5 E():0 41.2% identity in 376 aa overlap. Also similar to Streptomyces coelicolor TR:CAB46 [...] (391 aa)
SCO1454SCL6.11c, possible amino oxidase, len: 565 aa; similar to C-terminal region of SW:TR2M_AGRVI (EMBL:M91609) Agrobacterium vitis tryptophan 2-monooxygenase (EC 1.13.12.3) IaaM (auxins biosynthesis), 723 aa; fasta scores: opt: 617 z-score: 725.3 E(): 5.6e-33; 30.9% identity in 557 aa overlap. Contains Pfam match to entry PF01593 Amino_oxidase, Flavin containing amine oxidase. (565 aa)
SCO1464Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
SCO1477Putative flavoprotein homologue (partial); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (427 aa)
SCO1509SC9C5.33c, possible hydrolase, len: 235 aa; similar to SW:YCBL_ECOLI (EMBL:AE000195) Escherichia coli hypothetical 23.8 kD protein in MukB-AspC intergenic region YcbL, 215 aa; fasta scores: opt: 284 z-score: 328.0 E(): 8.4e-11; 32.6% identity in 215 aa overlap and to TR:CAB83688 (EMBL:AL162753) Neisseria meningitidis putative hydrolase NMA0387, 210 aa; fasta scores: opt: 239 z-score: 277.9 E(): 5.2e-08; 32.5% identity in 206 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily. (235 aa)
SCO1522Conserved hypothetical protein SCL2.12c; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (202 aa)
SCO1609SCI35.31, unknown, len: 402 aa; similar to a hypothetical protein from M. tuberculosis TR:O06802 (EMBL:Z95890) MTCY28.35 (414 aa), fasta scores; opt: 1341 z-score: 1649.4 E(): 0, 53.8% identity in 398 aa overlap. (402 aa)
SCO1660Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (512 aa)
SCO1682SCI30A.03, probable zinc-binding alcohol dehydrogenase, len: 358 aa; similar to many both prokaryote and eukaryote e.g. SW:DHSO_BACSU sorbitol dehydrogenase from Bacillus subtilis (352 aa) fasta scores; opt: 616, z-score: 638.0, E(): 3.3e-28, (32.7% identity in 352 aa overlap) and DHSO_SHEEP sorbitol dehydrogenase from Ovis aries (sheep) (354 aa) fasta scores; opt: 606, z-score: 627.7, E(): 1.2e-27, (34.6% identity in 344 aa overlap). Conatins Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. (358 aa)
SCO1690SCI30A.11, possible acyl-CoA dehydrogenase, len: 404 aa; varying similarity to many e.g. TR:P96831 (EMBL:Z92770) hypothetical protein from Mycobacterium tuberculosis (403 aa) fasta scores; opt: 1464, z-score: 1688.2, E(): 0, (57.3% identity in 400 aa overlap) and SW:ACDB_BACSU acyl-CoA dehydrogenase from Bacillus subtilis (379 aa) fasta scores; opt: 465, z-score: 539.6, E(): 1e-22, (32.0% identity in 347 aa overlap). Contains two Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (404 aa)
SCO1696Conserved hypothetical protein; SCI30A.17, unknown, len: 244 aa; similar to TR:P71976 (EMBL:Z81360) hypothetical protein from Mycobacterium tuberculosis (272 aa) fasta scores; opt: 192, z-score: 223.1, E(): 4.3e-05, (26.7% identity in 236 aa overlap) and to TR:Q98JP6 (EMBL:AP002998) Rhizobium loti (Mesorhizobium loti) MLL1845 241 aa; fasta scores: opt: 534 Z-score: 595.0 E(): 1.7e-25; 41.564% identity in 243 aa overlap. (244 aa)
SCO1701SCI30A.22c, probable acyl-CoA dehydrogenase, len: 383 aa; similar to many both prokaryote and eukaryote eg. SW:ACDB_BACSU acyl-CoA dehydrogenase from Bacillus subtilis (379 aa) fasta scores; opt: 109,1 z-score: 1197.8, E(): 0, (43.8% identity in 377 aa overlap) and SW:ACDS_RAT acyl-CoA dehydrogenase from Rattus norvegicus (Rat) (412 aa) fasta scores; opt: 1079, z-score: 1184.2, E(): 0, (44.6% identity in 372 aa overlap). Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (383 aa)
SCO1705SCI30A.26c, probable alcohol dehydrogenase (zinc-binding), len: 365 aa; similar to many e.g. SW:ADH3_ECOLI alcohol dehydrogenase class III from Escherichia coli (369 aa) fasta scores; opt: 819, z-score: 864.3, E(): 0, (38.6% identity in 368 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite matche to PS00059 Zinc-containing alcohol dehydrogenases signature. (365 aa)
SCO1715Putative homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (441 aa)
SCO17502SCI34.03c, probable acyl CoA dehydrogenase, len: 397 aa; similar to many dehydrogenases, e.g. SW:GCDH_HUMAN (EMBL:U69141) Homo sapiens (Human) glutaryl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.7) GcdH, 438 aa; fasta scores: opt: 1208 z-score: 1358.9 E(): 0; 48.2% identity in 398 aa overlap. Contains 2x Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (397 aa)
SCO0907SCM1.40c, possible dehydrogenase, len: 296 aa. Similar to many including: Pseudomonas cruciviae TR:Q9ZNH7 (EMBL:AB015439) D-threonine dehydrogenase (fragment) (292 aa), fasta scores opt: 458 z-score: 510.7 E(): 4.5e-21 33.0% identity in 297 aa overlap. (296 aa)
SCO07753SCF60.07, conserved hypothetical protein, len: 149 aa; identical to TR:O85698 (EMBL:AF072709) Streptomyces lividans hypothetical 16.7 kDa protein, 149 aa and similar to SW:YF58_MYCTU (EMBL:Z74020) Mycobacterium tuberculosis hypothetical 16.4 kDa protein MTCY48.07c, 148 aa; fasta scores: opt: 695 z-score: 894.5 E(): 0; 69.1% identity in 149 aa overlap. (149 aa)
SCO07703SCF60.02c, possible membrane protein, len: 185 aa. Contains possible hydrophobic membrane spanning region. (185 aa)
SCO07413SC5B7.19c, probable oxidoreductase, len: 362 aa; highly similar to SW:FADH_AMYME Amycolatopsis methanolica NAD/mycothiol-dependent formaldehyde dehydrogenase (EC 1.2.1.-) FadH, 360 aa; fasta scores: opt: 1833 z-score: 1972.8 E(): 0; 74.4% identity in 359 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and matches to Prosite entries PS00190 Cytochrome c family heme-binding site signature, PS00059 Zinc-containing alcohol dehydrogenases signature and PS00435 Peroxidases proximal heme-ligand signature. (362 aa)
SCO07403SC5B7.18c, probable hydrolase, len: 209 aa; identical to previously sequenced TR:Q9ZNB2 (EMBL:AB019513) Streptomyces coelicolor similar to Mycobacterium Tuberculosis hypothetical protein RV2260, 209 aa and similar to SW:GL2M_ARATH (EMBL:U90928) Arabidopsis thaliana hydroxyacylglutathione hydrolase, mitochondrial precursor (EC 3.1.2.6) Glx2-1, 331 aa; fasta scores: opt: 230 z-score: 271.1 E(): 1.4e-07; 30.1% identity in 173 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily. (209 aa)
SCO1773SCI51.13c, probable L-alanine dehydrogenase, len: 371 aa; similar to many alanine dehydrogenases e.g. SW:DHA_MYCTU (EMBL:X63069), ald, Mycobacterium tuberculosis L-alanine dehydrogenase (371 aa), fasta scores; opt: 1569 z-score: 1722.1 E(): 0, 65.8% identity in 371 aa overlap. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase and PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. (371 aa)
SCO1844SCI8.29c, possible aldolase, len: 240 aa. Similar to many aldolases e.g. Escherichia coli SW:FUCA_ECOLI (EMBL: M31059) L-fuculose phosphate aldolase (EC 4.1.2.17) (215 aa), fasta scores opt: 485 z-score: 552.3 E(): 2.1e-23 42.3% identity in 194 aa overlap. Contains a Pfam match to entry PF00596 Aldolase_II, Class II Aldolase and Adducin N-terminal domain. (240 aa)
SCO1861SCI39.08c, conserved hypothetical protein, len: 363 aa; similar to SW:YT15_MYCTU (EMBL:Z74697) Mycobacterium tuberculosis hypothetical 39.8 kDa protein RV2915c, 370 aa; fasta scores: opt: 1341 Z-score: 1487.0 bits: 283.8 E(): 3.1e-75; 56.630% identity in 362 aa overlap. (363 aa)
SCO1867Putative hydroxylase; Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2- oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine. (280 aa)
SCO1884Hypothetical protein; SCI7.02c, unknown, len: 281aa. (281 aa)
SCO1885SCI7.03c, possible oxidoreductase, len: 385 aa; similar to many proteins of undefined function eg. TR:Q45376 (EMBL:X90711) from a locus required for lipopolysaccharide biosynthesis in Bordetella pertussis (350 aa) fasta scores; opt: 232, z-score: 266.7, E(): 1.6e-07, (28.0% identity in 275 aa overlap). Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (385 aa)
SCO5364Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
SCO5399SC8F4.03, thiL, probable acetoacetyl-coA thiolase, len: 401aa; similar to many eg. SW:P14611 (THIL_ALCEU) acetoacetyl-coA thiolase from Alcaligenes eutrophus (393 aa) fasta scores; opt: 1272, z-score: 1344.2, E(): 0, 53.6% identity in 390 aa overlap. Also similar to TR:Q9XAM9 (EMBL:AL079355) beta-ketoadipyl-coA thiolase from Streptomyces coelicolor (cosmid 4C6) (400 aa) fasta scores; opt: 949, z-score: 919.8, E(): 0, 42.0% identity in 393 aa overlap. Contains Pfam match to entry PF00108 thiolase and Prosite matches to PS00098 Thiolases acyl-enzyme intermediate signature, PS00737 Thiola [...] (401 aa)
SCO54266-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (341 aa)
SCO5470Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
SCO5471Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
SCO5472Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (372 aa)
SCO5519Conserved hypothetical protein; SC8D9.31, unknown, len: 308aa; similar to proteins of undefined function eg. TR:O50444 (EMBL:AL010186) from Mycobacterium tuberculosis (329 aa) fasta scores; opt: 984, z-score: 1121.1, E(): 0, (50.0% identity in 312 aa overlap). (308 aa)
SCO5525SC1C2.06, ureAB, probable fusion of urease beta and gamma subunits, len: 227 aa; N-terminus is similar to UreA e.g. URE3_ECOLI urease gamma subunit (EC 3.5.1.5) (100 aa), fasta scores; opt: 300 z-score: 398.9 E(): 5.7e-15, 44.4% identity in 99 aa overlap; C-terminus is similar to ureB e.g. URE2_YEREN urease beta subunit (EC 3.5.1.5) (163 aa), fasta scores; opt: 303 z-score: 390.6 E(): 1.6e-14, 40.9% identity in 132 aa overlap. This fusion also exists in Helicobacters, where it is called the urease alpha subunit; URE1_HELFE urease alpha subunit (EC 3.5.1.5) (237 aa), fasta scores; opt: [...] (227 aa)
SCO5526SC1C2.07, ureC, probable urease alpha subunit, len: 558 aa; similar to many e.g. URE1_YEREN urease alpha subunit (EC 3.5.1.5) (571 aa), fasta scores; opt: 1676 z-score: 1972.3 E(): 0, 45.2% identity in 564 aa overlap. Contains PS01120 Urease nickel ligands signature and Pfam match to entry PF00449 urease, Urease, score 758.30, E-value 3.3e-224; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (558 aa)
SCO5546SC1C2.27, unknown, len: 261 aa; similar to hypothetical proteins e.g. E. coli TR:P76004 (EMBL:AE000216) O219 (219 aa), fasta scores; opt: 555 z-score: 764.8 E(): 0, 45.7% identity in 208 aa overlap and to e.g. HPCE_ECOLI 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (405 aa), fasta scores; opt: 389 z-score: 507.2 E(): 5.3e-21, 33.9% identity in 218 aa overlap. (261 aa)
SCO5680SC5H4.04c, probable cytidine deaminase, len: 137 aa; similar to TR:O53367 (EMBL:AL021841) Mycobacterium tuberculosis cytidine deaminase Cdd, 133 aa; fasta scores: opt 185 z-score: 244.6 E(): 3.6e-06; 37.4% identity in 115 aa overlap and to SW:CDD_MOUSE (EMBL:AA388666) Mus musculus cytidine deaminase (EC 3.5.4.5) Cdd, 146 aa; fasta scores: opt: 173 z-score: 229.1 E(): 2.6e-05; 29.2% identity in 113 aa overlap. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region and match to Prosite entry PS00903 Cytidine and deoxycytidylate deam [...] (137 aa)
SCO5693SC5H4.17, probable acyl CoA dehydrogenase, len: 658 aa; similar to SW:ACDV_BOVIN (EMBL:U30817) Bos taurus acyl-CoA dehydrogenase, very-long-chain specific precursor (EC 1.3.99.-) VlcaD, 655 aa; fasta scores: opt: 768 z-score: 864.8 E(): 0; 31.0% identity in 616 aa overlap. Contains 2x Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. (658 aa)
SCO5773SC4H8.12c, possible monooxygenase, len: 541 aa; weakly similar to many eg. TR:Q54171 (EMBL:X87093) putative oxygenase urdE from Streptomyces fradiae (495 aa), fasta scores; opt: 333 z-score: 428.9 E(): 1.1e-16, 30.4% identity in 539 aa overlap. (541 aa)
SCO5860SC2E9.01, suhB, probable extragenic suppressor protein, partial CDS, len: >209 aa, similar to eg. SUHB_ECOLI P22783 extragenic suppressor protein Suhb (267 aa), fasta scores; opt: 448 z-score: 565.9 E(): 2.5e-24, 41.0% identity in 212 aa overlap, and to eg. MYO2_LYCES P54927 myo-inositol-1(or 4)-monophosphatase (265 aa), fasta scores; opt: 359 z-score: 450.8 E(): 6.6e-18, 38.7% identity in 199 aa overlap. Contains PS00629 and PS00630 Inositol monophosphatase family signatures 1 and 2 and Pfam match to entry inositol_P PF00459, Inositol monophosphatase family, score 64.03. Overlaps and [...] (272 aa)
SCO5879Acyl-coa dehydrogenase RedW; Involved in the biosynthesis of undecylprodigiosin. Catalyzes the desaturation of the L-prolyl-[prolyl-carrier protein] to yield 1H-pyrrole-2-carbonyl- [prolyl-carrier protein]. (391 aa)
SCO5938Conserved hypothetical protein SC7H1.08c; SC7H1.08c, unknown, len: 202 aa; some similarity in C-terminus to Mycobacterium tuberculosis hypothetical protein TR:P71839 (EMBL:Z80226) MTCY369.30C (129 aa), fasta scores; opt: 240 z-score: 383.0 E(): 3.8e-14, 41.2% identity in 102 aa overlap. (202 aa)
SCO5948SC7H1.18, possible oxidoreductase, len: 397 aa; weak similarity to TCMG_STRGA P39888 tetracenomycin polyketide synthesis hydroxylase (572 aa), fasta scores; opt: 72 z-score: 275.1 E(): 4e-08, 26.0% identity in 369 aa overlap. Also similar to M. tuberculosis hypothetical protein Y08M_MYCTU Q11058 MTCY50.22c (372 aa), fasta scores; opt: 949 z-score: 613.3 E(): 5.8e-27, 45.9% identity in 355 aa overlap. (397 aa)
SCO5975SCBAC16H6.10, arcA2, arginine deiminase, len: 418 aa: similar to many e.g. SW:Q9RJN1 (ARCA_STRCO) arginine deaminase ArcA SCF55.37 from Streptomyces coelicolor (420 aa) fasta scores; opt: 1124, Z-score: 1310.8, 43.350% identity (43.781% ungapped) in 406 aa overlap and SW:O31017 (ARCA_RHIET) arginine deaminase from Rhizobium etli (409 aa) fasta scores; opt: 1153, Z-score: 1344.7, 45.854% identity (47.000% ungapped) in 410 aa overlap. Contains Pfam match to entry PF02726 Arg_deiminase, Arginine deiminase. (418 aa)
SCO5984SCBAC16H6.19, possible acyl-CoA dehydrogenase, len: 391aa: similar to many eg. SW:P16219 (ACDS_HUMAN) acyl-CoA dehydrogenase from Homo sapiens (412 aa) fasta scores; opt: 676, Z-score: 741.3, 35.121% identity (37.006% ungapped) in 373 aa overlap and SW:P96879 (ACDP_MYCTU) probable acyl-CoA dehydrogenase from Mycobacterium tuberculosis (389 aa) fasta scores; opt: 735, Z-score: 805.9, 35.676% identity (37.394% ungapped) in 370 aa overlap. Contains Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain; Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogen [...] (391 aa)
SCO6026SC1C3.14c, probable fatty acid oxidation complex alpha-subunit, similar to many e.g. FADB_ECOLI (729 aa), fasta scores; opt: 782 z-score: 863.1 E(): 0, 29.8% identity in671 aa overlap. Contains Pfam match to entry ECH PF00378, Enoyl-CoA hydratase/isomerase, score 49.78. (709 aa)
SCO6027SC1C3.15c, probable acetyl-coA acetyltransferase (thiolase), len: 405 aa; similar to many e.g. E. coli TR:E242886 (EMBL:X97452 acetyl-coA acetyltransferase paaJ (401 aa), fasta scores; opt: 718 z-score: 1313.7 E(): 0, 42.6% identity in 408 aa overlap. Contains Pfam match to entry thiolase PF00108, Thiolases, score 410.31; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
SCO6033Hypothetical protein SC1C3.21; SC1C3.21, unknown, len: 364 aa. (364 aa)
SCO6106SCBAC1A6.30c, possible acyl-CoA dehydrogenase, len: 557 aa; similar to SW:AIDB_ECOLI (EMBL:L20915) Escherichia coli AidB protein, 541 aa; fasta scores: opt: 916 z-score: 1055.7 E(): 0; 45.5% identity in 539 aa overlap and to TR:CAC13064 (EMBL:AL445503) Streptomyces coelicolor putative oxidoreductase 2SCG38.05, 567 aa; fasta scores: opt: 1480 z-score: 1414.3 E(): 0; 61.8% identity in 555 aa overlap. Contains Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase and match to Prosite entry PS00072 Acyl-CoA dehydrogenases signature 1 and PS00073 Acyl-CoA dehydrogenases signature 2. (557 aa)
SCO6201SC2G5.22, gcl, probable glyoxylate carboligase, acetohydroxy acid synthase-pyruvate oxidase family,len:594aa; highly similar to SW:GCL_ECOLI glyoxylate carboligase from Escherichia coli (592 aa) fasta scores;opt: 2905, z-score: 3262. 8,E(): 0, (72.7% identity in 586aa overlap). Contains Pfam match to entry PF00205TPP_enzymes, Thiamine pyrophosphate enzymes, score 427.80, E-value 4.7e-132. Note: as with the Escherichia coli homologue, this CDS is located close to a glyoxylate induced protein of unknown function. (594 aa)
SCO6205SC2G5.26c, probable dehydrogenase, len: 296aa; similar to many eg. TR:D1035162 (EMBL:AB015439) D-threonine dehydrogenase (292 aa) fasta scores; opt: 628, z-score:702.7, E(): 7.4e-32, (37.6% identity in 290 aa overlap). (296 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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