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SCO4567 SCO4567 SCO4568 SCO4568 SCO4570 SCO4570 SCO4600 SCO4600 SCO4603 SCO4603 SCO4767 SCO4767 SCO4947 SCO4947 SCO5044 SCO5044 SCO5046 SCO5046 SCO5058 SCO5058 SCO5135 SCO5135 SCO5190 SCO5190 SCO5469 SCO5469 SCO5553 SCO5553 SCO5645 SCO5645 SCO5696 SCO5696 SCO5752 SCO5752 SCO5787 SCO5787 SCO5901 SCO5901 SCO5926 SCO5926 SCO5999 SCO5999 SCO6100 SCO6100 SCO6102 SCO6102 SCO6148 SCO6148 SCO6290 SCO6290 SCO6481 SCO6481 SCO6535 SCO6535 SCO6559 SCO6559 SCO6560 SCO6560 SCO4550 SCO4550 SCO4495 SCO4495 SCO5240 SCO5240 SCO4494 SCO4494 SCO4429 SCO4429 SCO4086 SCO4086 SCO6561 SCO6561 SCO6715 SCO6715 SCO6767 SCO6767 SCO6922 SCO6922 SCO7106 SCO7106 SCO2573 SCO2573 SCO3034 SCO3034 SCO3355 SCO3355 SCO3569 SCO3569 SCO3579 SCO3579 SCO3928 SCO3928 SCO3938 SCO3938 SCO4047 SCO4047 SCP1.161c SCP1.161c SCP1.160c SCP1.160c SCP1.95 SCP1.95 SCO7525 SCO7525 SCO7374 SCO7374 SCO7306 SCO7306 SCO7110 SCO7110 SCO0216 SCO0216 SCO1244 SCO1244 SCO1711 SCO1711 SCO1821 SCO1821 SCO1990 SCO1990 SCO2004 SCO2004 St6G10A.01 St6G10A.01 SCO2194 SCO2194 SCO2473 SCO2473 SCO2559 SCO2559 SCO4563 SCO4563
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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SCO4567NuoF, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. (449 aa)
SCO4568NuoG, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 75 kDa subunit family. (843 aa)
SCO4570NuoI, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (211 aa)
SCO4600NADH dehydrogenase subunit NuoB2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (232 aa)
SCO4603NADH dehydrogenase subunit NuoI2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (197 aa)
SCO4767Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity). Plays a positive role in prespore maturation and the initiation of sporulation septation. (112 aa)
SCO49472SCK31.07, narG3, nitrate reductase alpha chain, len: 1227 aa; highly similar to SW:NARG_BACSU (EMBL:Z49884) Bacillus subtilis nitrate reductase alpha chain (EC 1.7.99.4)NarG, 1228 aa; fasta scores: opt: 4080 z-score: 4618.0 E(): 0; 49.5% identity in 1206 aa overlap and to TR:O86717 (EMBL:AL031515) Streptomyces coelicolor NarG, putative nitrate reductase alpha chain SC5C7.20, 1231 aa; fasta scores: opt: 5648 z-score: 5294.1 E(): 0; 66.6% identity in 1232 aa overlap. Contains Pfam matches to entries PF00384 molybdopterin, Prokaryotic molybdopterin oxidoreductases and PF01568 Molydop_bin [...] (1227 aa)
SCO5044Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (558 aa)
SCO5046Hypothetical protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (125 aa)
SCO5058Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (338 aa)
SCO5135Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (106 aa)
SCO5190Putative DNA-binding protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (122 aa)
SCO5469SC2A11.03c, sdaA, probable L-serine dehydratase, len: 455 aa; highly similar to e.g. SDHL_ECOLI L-serine dehydratase 1 (EC 4.2.1.13) (454 aa), fasta scores; opt: 1643 z-score: 1576.6 E(): 0, 55.6% identity in 459 aa overlap. (455 aa)
SCO55533-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (476 aa)
SCO5645Conserved hypothetical protein SC6A9.22c; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (368 aa)
SCO5696Hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (385 aa)
SCO5752Conserved hypothetical protein SC7C7.07; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (493 aa)
SCO5787Conserved hypothetical protein SC4H2.08; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (505 aa)
SCO5901Putative RNA methyltransferase; SC10A5.06, unknown, len: 458; similar to M. tuberculosis hypothetical protein TR:O07191 (EMBL:Z96072) MTCY05A6. 10C (405 aa), fasta scores; opt: 455 z-score: 878.5 E(): 0, 38.4% identity in 417 aa overlap, and weakly similar to several putative RNA methyltransferases eg. YGCA_ECOLI P5513 5 hypothetical RNA methyltransferase (433 aa), fasta scores; opt: 358 z-score: 331.2 E(): 3e-11, 27.4% identity in 441 aa overlap; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (458 aa)
SCO5926Conserved hypothetical protein; SC10A5.31c, unknown, len: 173 aa; highly similar to the C-terminus of many prokaryotic and eukaryotic aconitase s eg. ACO1_ECOLI P25516 aconitate hydratase 1 (ec 4.2.1.3) (890 aa), fasta scores; opt: 422 z-score: 567.1 E(): 2.2e-2 4, 49.3% identity in 138 aa overlap; Belongs to the LeuD family. (173 aa)
SCO5999Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
SCO6100Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (236 aa)
SCO6102SCBAC1A6.26c, probable nitrite/sulphite reductase, len: 565 aa; similar to SW:NIR_SYNP7 (EMBL:D12723) Synechococcus sp. ferredoxin--nitrite reductase (EC 1.7.7.1) NirA, 512 aa; fasta scores: opt: 935 z-score: 1113.1 E(): 0; 35.6% identity in 525 aa overlap. Contains Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain. (565 aa)
SCO6148Hypothetical protein SC1A9.12; SC1A9.12, unknown, len: 442 aa. (442 aa)
SCO6290SCBAC8D1.03, hypothetical protein, len: 84 aa; highly similar to N-terminal part of SW:SOXA_RHIME (EMBL:AF055582) Rhizobium meliloti sarcosine oxidase alpha subunit (EC 1.5.3.1) SoxA, 987 aa; fasta scores: opt: 132 Z-score: 169.8 bits: 39.3 E(): 0.072l; 42.373% identity in 59 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains. (84 aa)
SCO6481SC9C7.17c, conserved hypothetical protein, len: 348aa; similar to several hypothetical proteins eg. SW:Y0BN_MYCTU from Mycobacterium tuberculosis (340 aa) fasta scores; opt: 998, z-score: 1321.8, E(): 0, (47.6% identity in 355 aa overlap). (348 aa)
SCO6535SC5C7.20c, narG, probable nitrate reductase alpha chain, len: 1231 aa; highly similar to many e.g. NARG_BACSU nitrate reductase alpha chain (EC 1.7.99.4) (1228 aa), fasta scores; opt: 4306 z-score: 3216.7 E(): 0, 51.5% identity in 1235 aa overlap. Contains PS00551 and PS00490 Prokaryotic molybdopterin oxidoreductases signatures 1 and 2 and Pfam match to entry PF00384 molybdopterin, Prokaryotic molybdopterin oxidoreductases, score 79.90, E-value 1e-24; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1231 aa)
SCO6559SC4B5.09c, respiratory chain oxidoreductase, len: 286 aa; similar to the N-terminal region of many proteins involved in electron transfer e.g. TR:P77908 (EMBL:U73807) FdhA formate dehydrogenase alpha subunit from Moorella thermoacetica (893 aa), fasta scores; opt: 685, z-score: 791.8, E(): 0, (38.4% identity in 284 aa overlap). Contains PS00551 Prokaryotic molybdopterin oxidoreductases signature 1, PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature, PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature, Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and r [...] (286 aa)
SCO6560SC4B5.10c, respiratory chain oxidoreductase, len: 646 aa; C-terminal region is similar to the N-terminal region of many proteins involved in electron transfer e.g. TR:O27592 (EMBL:AE000915) NADP-reducing hydrogenase, subunit C from Methanobacterium thermoautotrophicum (630 aa), fasta scores; opt: 121,4 z-score: 1170.7, E(): 0, (47.1% identity in 397 aa overlap). Contains PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. (646 aa)
SCO4550Conserved hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (399 aa)
SCO4495SCD35.02, possible DNA polymerase related protein, len: 212 aa; similar to TR:AAF11304 (EMBL:AE002016) Deinococcus radiodurans DNA polymerase-related protein DR1751, 237 aa; fasta scores: opt: 380 z-score: 451.4 E(): 1e-1; 41.5% identity in 188 aa overlap and to N-terminal region of SW:DPOL_BPSP1 (EMBL:M84415) Bacteriophage SP01 DNA polymerase (EC 2.7.7.7) 31, 924 aa; fasta scores: opt: 191 z-score: 223.4 E(): 5.2e-05; 33.7% identity in 169 aa overlap. (212 aa)
SCO5240Hypothetical protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (85 aa)
SCO4494Conserved hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
SCO4429Conserved hypothetical protein SCD6.07; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine; In the C-terminal section; belongs to the radical SAM superfamily. CofH family. (867 aa)
SCO4086Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (530 aa)
SCO6561SC4B5.11c, respiratory chain oxidoreductase, len: 642 aa; similar to the C-terminal region of many proteins involved in electron transfer e.g. TR:P77908 (EMBL:U73807) FdhA formate dehydrogenase alpha subunit from Moorella thermoacetica (893 aa) fasta scores; opt: 1532, z-score: 1338.5, E(): 0, (43.1% identity in 619 aa overlap). Contains Pfam match to entry PF00384 molybdopterin, Prokaryotic molybdopterin oxidoreductases, score 95.80, E-value 6.2e-30. Considering the corresponding homolgies, this CDS may have previously been located directly downsteam of SC4B5.09c. (642 aa)
SCO6715Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (81 aa)
SCO6767GcpE protein homolog, conserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (384 aa)
SCO6922Hypothetical protein SC1B2.28c; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (213 aa)
SCO7106Conserved hypothetical protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (88 aa)
SCO2573Putative oxidoreductase; SCC123.11, possible oxidoreductase, len: 524 aa. Weakly similar to several including: Homo sapiens (Human) SW:NUBM_HUMAN(EMBL:Y17379) NADH-ubiquinone oxidoreductase 51 KD subunit precursor (EC 1.6.5.3) (464 aa), fasta scores opt: 341 z-score: 369.2 E(): 3.6e-13 27.1% identity in 365 aa overlap and Streptomyces coelicolor TR:Q9XAQ9(EMBL:AL078618) NADH dehydrogenase subunit, NuoF (449 aa), fasta scores opt: 398 z-score: 430.5 E(): 1.4e-16 26.5% identity in 392 aa overlap. (524 aa)
SCO3034Sporulation regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity). Complements a whiB2 disruption mutant in M.smegmatis (AC Q9S426). (87 aa)
SCO3355SCE94.06, mutY, putative adenine glycosylase, len: 308 aa; previously partially sequenced therefore partially identical to TR:E1358524 (EMBL:AJ131213) MutY, putative adenine glycosylase from Streptomyces coelicolor (183 aa) fasta scores; opt: 1220, z-score: 1357.4, E(): 0, (100.0% identity in 183 aa overlap). Also similar to many others e.g. SW:MUTY_SALTY MutY, adenine glycosylase from Salmonella typhimurium (350 aa) fasta scores; opt: 500, z-score: 558.7, E(): 8.3e-24, (39.4% identity in 231 aa overlap). Contains Pfam match to entry PF00730 Endonuclease_3, Endonuclease III. (308 aa)
SCO3569Putative endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (250 aa)
SCO3579Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (112 aa)
SCO3928Putative thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (612 aa)
SCO3938SCD78.05, thiC', probable thiamin biosynthesis protein ThiC, partial CDS, len: 43 aa; simlar to the extreme C-terminus of e.g. THIC_ECOLI thiamin biosynthesis protein ThiC (631 aa), fasta scores; opt: 97 z-score: 137.7 E(): 2, 46.2% identity in 39 aa overlap and THIC_MYCTU (547 aa), fasta scores; opt: 143 z-score: 272.4 E(): 6.4e-08, 53.1% identity in 49 aa overlap. Note that this gene appears to have been interrupted by the integration of the upstream element. (43 aa)
SCO40472SCD60.13c, conserved hypothetical protein, len: 197 aa; similar to TR:O06554 (EMBL:Z95584) Mycobacterium tuberculosis hypothetical 20.8 kDa protein MTCI65.23, 197 aa; fasta scores: opt: 741 z-score: 862.4 E(): 0; 60.6% identity in 188 aa overlap. (197 aa)
SCP1.161cPutative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. Belongs to the sigma-70 factor family. ECF subfamily. (268 aa)
SCP1.160cSCP1.160c, possible oxidoreductase, len: 525aa; similar to many eg. TR:Q9RDL3 (EMBL:AL136518) putative oxidoreductase from Streptomyces coelicolor (524 aa) fasta scores; opt: 308,1 z-score: 3329.1, E(): 0, 88.9% identity in 523 aa overlap and SW:P56913 (NUF2_RHIME) NADH dehydrogenase I chain F 2 (EC 1.6.5.3) from Rhizobium meliloti (Sinorhizobium meliloti) (421 aa) fasta scores; opt: 367, z-score: 400.3, E(): 7.9e-15, 28.4% identity in 395 aa overlap. (525 aa)
SCP1.95Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (102 aa)
SCO7525SC8G12.01, possible oxidoreductase, partial CDS, len: >169 aa. Highly similar to several including: Streptomyces coelicolor TR:CAB52060(EMBL:AL109732) putative formate dehydrogenase, SC7H2.18 (759 aa), fasta scores opt:670 z-score: 812.0 E(): 0 62.3% identity in 167 aa overlap and Mycobacterium tuberculosis TR:YX31_MYCTU(EMBL:Z74024) hypothetical 84.6 kd protein (779 aa), fasta scores opt: 571 z-score: 692.2 E(): 4.3e-31 55.2% identity in 172 aa overlap; SCBAC25F8.17, probable oxidoreductase (fragment), len: >629 aa; similar to N-terminal reguion of TR:AAK47294 (EMBL:AE007119) Mycobact [...] (764 aa)
SCO7374Nitrate reductase NarB (fragment); SC10G8.01c, possible oxidoreductase, partial CDS, len: > 355 aa. Similar to many e.g. Paracoccus denitrificans SW:NAPA_PARDT (EMBL:Z36773) periplasmic nitrate reductase precursor (EC 1.7.99.4) (831 aa), fasta scores opt: 550 z-score: 651.4 E(): 7.2e-29 33.1% identity in 317 aa overlap; SC9H11.28c, narB, nitrate reductase (EC 1.7.99.4), partial CDS, len: > 508 aa. Highly similar to many including: Synechocystis sp. (strain PCC 7942) SW:NARB_SYNP7 (EMBL:X74597) nitrate reductase (EC 1.7.99.4), NarB (729 aa), fasta scores opt: 583 z-score: 613.8 E(): 1e- [...] (830 aa)
SCO7306Regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (83 aa)
SCO7110Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (129 aa)
SCO0216SCJ12.28, narG2, probable nitrate reductase alpha chain, len: 1233 aa. Highly similar to Streptomyces coelicolor TR:O86717 (EMBL; AL031515) putative nitrate reductase alpha chain NarG SC5C7.20c (1231 aa), fasta scores: opt: 5792 z-score: 6544.7 E(): 0 67.6% identity in 1230 aa overlap and Bacillus subtilis SW:NARG_BACSU (EMBL; Z49884) nitrate reductase alpha chain (EC 1.7.99.4) NarG (1228 aa), fasta scores: opt: 4331 z-score: 4891.8 E(): 0 52.9% identity in 1201 aa overlap. Contains a PS00551 Prokaryotic molybdopterin oxidoreductases signature 1, a Pfam match to entry PF00384 molybdopt [...] (1233 aa)
SCO1244Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (407 aa)
SCO1711SCI30A.32c, possible dehydrogenase, len: 747aa; similar to many e.g. TR:O53648 (EMBL:AL021928) hypothetical protein from Mycobacterium tuberculosis (762 aa) fasta scores; opt: 617, z-score: 625.8, E(): 1.6e-27, (29.9% identity in 762 aa overlap) and SW:FDHF_ECOLI formate dehydrogenase from Escherichia coli (715 aa) fasta scores; opt: 466, z-score: 473.3, E(): 4.9e-19, (24.0% identity in 716 aa overlap); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (747 aa)
SCO1821Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (341 aa)
SCO1990Conserved hypothetical protein; SC7H2.04c, unknown, len: 237aa; similar to SW:Y08N_MYCTU hypothetical protein from Mycobacterium tuberculosis (350 aa) fasta scores; opt: 870, z-score: 990.4, E(): 0, (57.1% identity in 231 aa overlap). (237 aa)
SCO2004SC7H2.18, possible formate dehydrogenase, len: 759 aa; similar to many formate dehydrogenase e.g. SW:FDHF_ECOLI formate dehydrogenase H from Escherichia coli (715 aa) fasta scores; opt: 386, z-score: 441.8, E(): 2.8e-17, (26.3% identity in 670 aa overlap). Also similar to SW:YX31_MYCTU hypothetical protein from Mycobacterium tuberculosis (779 aa) fasta scores; opt: 3038, z-score: 3497.1, E(): 0, (59.7% identity in 767 aa overlap); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (759 aa)
St6G10A.01Putative quinolinate synthetase (fragment); Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (394 aa)
SCO2194Putative lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (317 aa)
SCO2473SC7A8.12, probable nitrate reductase, len: 819 aa; similar to SW:NASC_BACSU (EMBL:D50453) Bacillus subtilis assimilatory nitrate reductase catalytic subunit (EC 1.7.99.4) NasC, 710 aa; fasta scores: opt: 1568 z-score: 1572.1 E(): 0; 37.9% identity in 816 aa overlap. Contains Pfam matches to entries PF00384 molybdopterin, Prokaryotic molybdopterin oxidoreductases and PF01568 Molydop_binding, Molydopterin dinucleotide binding domain. Contains also glycine/serine rich region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (819 aa)
SCO2559Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (435 aa)
SCO4563NuoB, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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