(8 nodes) Large ribosomal subunit network (Streptomyces coelicolor)

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	SCO4721	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa)
	SCO5571	SC7A1.15, rpmF, 50S ribosomal protein L32, len: 57 aa; similar to many eg. SW:RL32_BACST 50S PrmF, ribosomal protein L32 from Bacillus stearothermophilus (56 aa) fasta scores; opt: 180, z-score: 341.1, E(): 1.1e-11, (48.1% identity in 54 aa overlap). (57 aa)
	SCO0436	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap. (56 aa)
	SCO4702	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (214 aa)
	SCO4705	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (278 aa)
	SCO4712	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
	SCO4714	50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa)
	SCO4720	SCD31.45, rpmD, 50S ribosomal protein L30, len: 60 aa; identical to previously sequenced SW:RL30_STRCO (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein L30 RpmD, 60 aa. Contains Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e and match to Prosite entry PS00634 Ribosomal protein L30 signature. (60 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO0436	SCO4702	gene:17758019	gene:17762351	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.974
SCO0436	SCO4705	gene:17758019	gene:17762354	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.977
SCO0436	SCO4712	gene:17758019	gene:17762361	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.979
SCO0436	SCO4714	gene:17758019	gene:17762363	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.974
SCO0436	SCO4720	gene:17758019	gene:17762369	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	SCD31.45, rpmD, 50S ribosomal protein L30, len: 60 aa; identical to previously sequenced SW:RL30_STRCO (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein L30 RpmD, 60 aa. Contains Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e and match to Prosite entry PS00634 Ribosomal protein L30 signature.	0.978
SCO0436	SCO4721	gene:17758019	gene:17762370	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.978
SCO0436	SCO5571	gene:17758019	gene:17763229	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	SC7A1.15, rpmF, 50S ribosomal protein L32, len: 57 aa; similar to many eg. SW:RL32_BACST 50S PrmF, ribosomal protein L32 from Bacillus stearothermophilus (56 aa) fasta scores; opt: 180, z-score: 341.1, E(): 1.1e-11, (48.1% identity in 54 aa overlap).	0.900
SCO4702	SCO0436	gene:17762351	gene:17758019	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	0.974
SCO4702	SCO4705	gene:17762351	gene:17762354	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
SCO4702	SCO4712	gene:17762351	gene:17762361	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.999
SCO4702	SCO4714	gene:17762351	gene:17762363	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.999
SCO4702	SCO4720	gene:17762351	gene:17762369	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	SCD31.45, rpmD, 50S ribosomal protein L30, len: 60 aa; identical to previously sequenced SW:RL30_STRCO (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein L30 RpmD, 60 aa. Contains Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e and match to Prosite entry PS00634 Ribosomal protein L30 signature.	0.998
SCO4702	SCO4721	gene:17762351	gene:17762370	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
SCO4702	SCO5571	gene:17762351	gene:17763229	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	SC7A1.15, rpmF, 50S ribosomal protein L32, len: 57 aa; similar to many eg. SW:RL32_BACST 50S PrmF, ribosomal protein L32 from Bacillus stearothermophilus (56 aa) fasta scores; opt: 180, z-score: 341.1, E(): 1.1e-11, (48.1% identity in 54 aa overlap).	0.974
SCO4705	SCO0436	gene:17762354	gene:17758019	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	SCF51A.14, possible 50S ribosomal protein L32, len: 56 aa. Similar to many including: Helicobacter pylori J99 SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 30.2% identity in 43 aa overlap and highly similar to the N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity in 28 aa overlap.	0.977
SCO4705	SCO4702	gene:17762354	gene:17762351	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.999
SCO4705	SCO4712	gene:17762354	gene:17762361	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.999
SCO4705	SCO4714	gene:17762354	gene:17762363	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.999
SCO4705	SCO4720	gene:17762354	gene:17762369	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	SCD31.45, rpmD, 50S ribosomal protein L30, len: 60 aa; identical to previously sequenced SW:RL30_STRCO (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein L30 RpmD, 60 aa. Contains Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e and match to Prosite entry PS00634 Ribosomal protein L30 signature.	0.999
SCO4705	SCO4721	gene:17762354	gene:17762370	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999