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SCO7700 SCO7700 SCO0374 SCO0374 SCO0755 SCO0755 SCO0756 SCO0756 SCO0896 SCO0896 SCO5207 SCO5207 SCO5222 SCO5222 SCO6073 SCO6073
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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SCO7700Putative cyclase; Catalyzes the cyclization of 2-methylgeranyl diphosphate (2- MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate. Is also able to catalyze the cyclization of geranyl diphosphate (GPP), albeit with much lower efficiency, leading to the formation of a complex mixture of cyclic monoterpenes, consisting of alpha-pinene (6%), beta-pinene (23%), limonene (32%), gamma-terpinene (29%), and delta-terpinene (10%). Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily. (440 aa)
SCO0374SCF41.33, putative ABC transport protein, len: 589 aa. Similar to many e.g. Streptomyces coelicolor TR:Q9ZNB0 (EMBL; AB019513) ABC transporter (584 aa), fasta scores opt: 597 z-score: 649.7 E(): 7.7e-29 30.9% identity in 572 aa overlap. Contains a Pfam match to entry PF00005 ABC_tran, ABC transporter and a PS00017 ATP/GTP-binding site motif A (P-loop). Contains membrane-spanning hydrophobic domains. (589 aa)
SCO0755SCF81.14, possible ABC transporter, len: 740 aa; similar to SW: COMA_STRPN (EMBL:M36180) Streptococcus pneumoniae transport ATP-binding protein ComA, 717 aa; fasta scores: opt: 1035 z-score: 1141.5 E(): 0; 29.1% identity in 721 aa overlap. Contains two matches to Pfam entries PF00664 ABC_membrane, ABC transporter transmembrane region and PF00005 ABC_tran, ABC transporter and two to Prosite entries PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transporters family signature. (740 aa)
SCO0756SCF81.15, possible ABC transporter, len: 940 aa; similar to TR:P74829 (EMBL:U51197) Sphingomonas sp. S88 hypothetical 79.4 KD protein AtrB, 728 aa; fasta scores: opt: 803 z-score: 870.4 E(): 0; 32.7% identity in 562 aa overlap and to SW:CYAB_BORPE (EMBL:X14199) Bordetella pertussis cyclolysin secretion ATP-binding protein CyaB, 712 aa; fasta scores: opt: 785 z-score: 851.0 E(): 0; 32.2% identity in 631 aa overlap. Contains two matches to Pfam entries PF00664 ABC_membrane, ABC transporter transmembrane region and PF00005 ABC_tran, ABC transporter and two to Prosite entries PS00017 ATP/G [...] (940 aa)
SCO0896Putative oxidoreductase; SCM1.29c, possible oxidoreductase, len: 141 aa. Similar to many including Methanopyrus kandleri SW:IMDH_METKA (EMBL:U31567) putative inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) (172 aa), fasta scores opt: 227 z-score: 288.9 E(): 9.5e-09 31.6% identity in 117 aa overlap and Bacillus subtilis SW:YHCV_BACSU (EMBL:X96983) hypothetical 14.9 KD protein (140 aa), fasta scores opt: 295 z-score: 372.8 E(): 2e-13 40.0% identity in 135 aa overlap. Contains 2x Pfam match to entry PF00571 CBS, CBS domains. (141 aa)
SCO5207SC7E4.04c, hypothetical protein, len: 145 aa; similar to TR:Q9YFH9 (EMBL:AP000058) Aeropyrum pernix hypothetical 15.7 kD protein APE0267, 143 aa; fasta scores: opt: 220 z-score: 282.8 E(): 2.8e-08; 34.1% identity in 126 aa overlap. Contains 2x Pfam match to entry PF00571 CBS, CBS domain. (145 aa)
SCO5222Putative lyase; Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene. (361 aa)
SCO6073Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. (726 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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