STRINGSTRING
SCO7095 SCO7095 SCO3171 SCO3171 SCO3566 SCO3566 SCO3540 SCO3540 SCO3233 SCO3233 SCO6612 SCO6612 SCO6697 SCO6697 SCO6966 SCO6966 SCO7100 SCO7100 SCO7121 SCO7121 SCO7132 SCO7132 SCO0805 SCO0805 SCO1989 SCO1989 SCO2208 SCO2208 SCO2332 SCO2332 SCO2516 SCO2516 SCO2886 SCO2886 SCO0526 SCO0526 SCO0470 SCO0470 SCO0465 SCO0465 SCO6175 SCO6175 SCO5986 SCO5986 SCO5943 SCO5943 SCO5172 SCO5172 SCO5165 SCO5165 SCO4746 SCO4746 SCO4479 SCO4479 SCO0267 SCO0267 SCO0145 SCO0145 SCO0135 SCO0135 SCO1264 SCO1264 SCO1230 SCO1230 SCO1097 SCO1097 SCO0939 SCO0939 SCO0899 SCO0899 SCO0878 SCO0878 SCO4395 SCO4395 SCO4392 SCO4392 SCO4160 SCO4160 SCO0461 SCO0461 SCO0427 SCO0427 SCO7205 SCO7205 SCO7245 SCO7245 SCO3690 SCO3690 SCO3954 SCO3954 SCO7256 SCO7256 SCO7440 SCO7440 SCO3574 SCO3574 SCO7609 SCO7609 SCO7777 SCO7777 SCO6479 SCO6479 SCO6351 SCO6351 SCO6339 SCO6339 SCO6277 SCO6277
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SCO7095SC3A4.21c, possible hydrolase. len: 318 aa. Similar in parts to several e.g. Moraxella sp. SW:DEH1_MORSP(EMBL:D90422) haloacetate dehalogenase H-1 (EC 3.8.1.3) (294 aa), fasta scores opt: 245 z-score: 286.4 E(): 1.7e-08 37.4% identity in 131 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (318 aa)
SCO3171SCE87.22c, possible hydrolase, len: 314 aa: Similar to several e.g. Mycobacterium tuberculosis TR:O53321 (EMBL: AL021646) hypothetical 32.1 KD protein (299 aa), fasta scores opt: 261 z-score: 297.3 E(): 3.5e-09 31.7% identity in 281 aa overlap and Streptomyces lividans SW:PRXC_STRLI (EMBL: U02635) non-heme chloroperoxidase (EC 1.11.1.10) (275 aa), fasta scores opt: 241 z-score: 275.2 E(): 5.9e-08 30.0% identity in 287 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (314 aa)
SCO3566SCH5.29, possible hydrolase, len: 324aa; similar to many egs. TR:O69638 (EMBL:AL022121) putative epoxide hydrolase from Mycobacterium tuberculosis (327 aa) fasta scores; opt: 687, z-score: 786.1, E(): 0, (40.7% identity in 327 aa overlap) and TR:Q39856 (EMBL:D63781) epoxide hydrolase from Glycine max (soybean) (341 aa) fasta scores; opt: 396, z-score: 455.4, E(): 4.6e-18, (29.1% identity in 316 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold, score 68.70, E-value 1.3e-16. (324 aa)
SCO3540SCH5.02c, slpD, proteinase (putative secreted protein), len: 539 aa; identical to the previously sequenced TR:Q54398 (EMBL:L42758) SlpD, mycelium-associated (lipoprotein) proteinase from Streptomyces lividans 66 (539 aa) fasta scores; opt: 3608, z-score: 3750.3, E(): 0, (100.0% identity in 539 aa overlap). Also similar to two other peptidases from Streptomyces coelicolor SC9C7.15c (EMBL:AL035161) fasta scores; opt: 666, z-score: 603.6, E(): 9.4e-29, (35.7% identity in 502 aa overlap) and SC1B5.03c (EMBL:AL023517) fasta scores; opt: 661, z-score: 598.9, E(): 1.7e-28, (32.6% identity in [...] (539 aa)
SCO3233SCE29.02, probable hydrolase, len: 272 aa; similar to many e.g. TR:O52809 (EMBL:AJ223998) from the vancomycin biosynthesis cluster of Amycolatopsis orientalis (276 aa) fasta scores; opt: 892, z-score: 1028.9, E(): 0, (50.9% identity in 271 aa overlap) and TR:O67982 (EMBL:AF003947) PcaL; single polypeptide combining 3-oxoadipate enol-lactone hydrolyzing and 4-carboxymuconolactone decarboxylating activityfrom Rhodococcus opacus (400 aa) fasta scores; opt: 288, z-score: 335.4, E(): 2.3e-11, (32.0% identity in 256 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hy [...] (272 aa)
SCO6612SC1F2.09c, probable hydrolase, len: 309 aa; similar to many e.g. XYLF_PSEPU 2-hydroxymuconic semialdehyde hydrolase (281 aa), fasta scores; opt: 236 z-score: 348.2 E(): 3.8e-12, 29.0% identity in 283 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha /beta hydrolase fold, score 52.80, E-value 7.5e-12. (309 aa)
SCO6697SC4C6.07c, pcaL, probable 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase, len: 375 aa; similar to TR:O67982 (EMBL:AF003947), pcaL, Rhodococcus opacus 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase (400 aa), fasta scores; opt: 401 z-score: 464.7 E(): 1.5e-18, 46.3% identity in 387 aa overlap the first approx. 260 aa is similar to SW:ELH2_ACICA (EMBL:AF009224), catD, Acinetobacter calcoaceticus 3-oxoadipate enol-lactonase II (266 aa) (35.1% identity in 248 aa overlap) while the remainder is similar to SW:DC4C_ACICA (EMBL:L05770), pcaC, [...] (375 aa)
SCO6966Putative lipase; SC6F7.19c, possible lipase, len: 269 aa. Similar to many other putative lipases e.g. Thermotoga maritima TR:Q9X171(EMBL:AE001789) lipase, putative (259 aa), fasta scores opt: 345 z-score: 396.1 E(): 1.3e-14 33.1% identity in 239 aa overlap. contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (269 aa)
SCO7100SC4B10.01, probable oxidoreductase, len: 260 aa; similar to TR:Q9RK83 (EMBL:AL132662) Streptomyces coelicolor possible oxidoreductase SCF11.06, 277 aa; fasta scores: opt: 208 z-score: 258.9 E(): 5.9e-07; 25.5% identity in 243 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (260 aa)
SCO7121SC4B10.22, possible secreted protein, len: 281 aa; similar to TR:Q9S1Z1 (EMBL:AL109747) Streptomyces coelicolor hypothetical 24.6 kDa protein SCJ21.16, 239 aa; fasta scores: opt: 989 z-score: 1075.6 E(): 0; 64.4% identity in 233 aa overlap and to Streptomyces coelicolor SC4B10.33, 239 aa; fasta scores: opt: 1034 z-score: 972.0 E(): 0; 67.0% identity in 233 aa overlap. Contains possible N-terminal region signal peptide sequence. (281 aa)
SCO7132SC4B10.33, conserved hypothetical protein, len: 239 aa; highly similar to TR:Q9S1Z1 (EMBL:AL109747) Streptomyces coelicolor hypothetical 24.6 kDa protein SCJ21.16, 239 aa; fasta scores: opt: 1227 z-score: 1384.6 E(): 0; 79.0% identity in 238 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold and match to Prosite entry PS00120 Lipases, serine active site. (239 aa)
SCO0805Putative prolyl aminopeptidase; SCF43.16c, possible prolyl aminopeptidase, len: 433 aa. Highly similar to several peptidases including: Aeromonas sobria SW:PIP_AERSO(EMBL:D30714) proline iminopeptidase (EC 3.4.11.5) (prolyl aminopeptidase) (424 aa), fasta scores opt: 954 z-score: 1113.1 E():0 48.6% identity in 428 aa overlap and Hafnia alvei TR:P94800(EMBL:D61383) prolyl aminopeptidase (427 aa), fasta scores opt: 1208 z-score: 1408.6 E():0 47.2% identity in 432 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (433 aa)
SCO1989Putative aminopeptidase; Specifically catalyzes the removal of N-terminal proline residues from peptides. (323 aa)
SCO2208SC10B7.03c, probable carboxylesterase, len: 290 aa; identical to previously sequenced TR:Q9X956 (EMBL:Y13833) Streptomyces coelicolor hypothetical 30.8 kD protein, 290 aa and similar to TR:Q59248 (EMBL:X82892) Bacillus subtilis carboxylesterase NP (EC 3.1.1.1) Nap, 300 aa; fasta scores: opt: 438 z-score: 516.3 E(): 2.2e-21; 31.5% identity in 292 aa overlap. (290 aa)
SCO2332SCC53.23, possible hydrolase, len: 259 aa; similar to many e.g. SW:Q59695 (ACOC_PSEPU) acetoin dehydrogenase E2 component from Pseudomonas putida (370 aa) fasta scores; opt: 213, z-score: 235.6, E(): 1.2e-05, 30.5% identity in 249 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. Also contains possible stem loop structure in %' half of CDS. (259 aa)
SCO2516SCC121.19, possible secreted protein, len: 499 aa; similar to TR:O69831 (EMBL:AL023517) Streptomyces coelicolor putative secreted protease SC1B5.03C, 543 aa; fasta scores: opt: 772 z-score: 821.6 E(): 0; 32.2% identity in 537 aa overlap. Contains possible N-terminal region signal peptide sequence. (499 aa)
SCO2886SCE6.23c, possible hydrolase, len: 294 aa. Similar to several including: Mycobacterium sp. TR:Q9ZER0 (EMBL:AJ012627) haloalkane dehalogenase, DhaAF (307 aa), fasta scores opt: 347 z-score: 425.8 E(): 2.7e-16 27.4% identity in 292 aa overlap and Deinococcus radiodurans TR:AAF12090 (EMBL:AE002084) epoxide hydrolase-related protein (278 aa), fasta scores opt: 402 z-score: 493.2 E(): 4.8e-2032.4% identity in 284 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (294 aa)
SCO0526SCF11.06, possible oxidoreductase, len: 277 aa; similar to TR:O53622 (EMBL:AL021428) Mycobacterium tuberculosis putative oxidoreductase MTV030.21c, 276 aa; fasta scores: opt: 276 z-score: 329.4 E(): 5.6e-11; 24.7% identity in 267 aa overlap and to SW:PRXC_PSEFL (EMBL:AF031153) Pseudomonas fluorescens non-heme chloroperodixase (EC 1.11.1.10) (chloride peroxidase) (CPO-F) (chloropeorixidase F) Cpo or CpoF; fasta scores: opt: 233 z-score: 279.3 E():3.5e-08; 26.1% identity in 283 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (277 aa)
SCO0470SCF76.10, possible hydrolase, len: 302 aa. Weakly similar to hydrolases e.g. the N-terminal, domain of Streptomyces coelicolor TR:O86608 (EMBL:AL031155) 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase (449 aa), fasta scores opt: 387 z-score: 428.9 E(): 1.6e-16 33.7% identity in 258 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (302 aa)
SCO0465SCF76.05c, non-heme chloroperoxidase (chloride peroxidase), len: 276 aa. Identical to Streptomyces lividans SW:PRXC_STRLI (EMBL; U02635) non-heme chloroperoxidase (EC 1.11.1.10) (chloride peroxidase)(CPO-L) (chloroperoxidase L) (275 aa), fasta scores opt: 1866 z-score: 2162.6 E():0 99.3% identity in 275 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (276 aa)
SCO6175SC6C5.11, hypothetical protein, len: 327 aa; similar to TR:Q9LAB8 (EMBL:AF144381) Burkholderia gladioli esterase EstC, 298 aa; fasta scores: opt: 532 Z-score: 590.8 E(): 2.8e-25; 38.014% identity in 292 aa overlap. (327 aa)
SCO5986SCBAC16H6.21, possible oxidoreductase, len: 275aa: similar to many eg. TR:O53622 (EMBL:AL021428) putative oxidoreductase from Mycobacterium tuberculosis (276 aa) fasta scores; opt: 521, Z-score: 601.4, 36.364% identity (38.314% ungapped) in 275 aa overlap and TR:Q53042 (EMBL:AF060871) haloalkane dehalogenase from Rhodococcus rhodochrous (293 aa) fasta scores; opt: 249, Z-score: 291.2, 28.417% identity (31.102% ungapped) in 278 aa overlap. (275 aa)
SCO5943SC7H1.13, probable hydrolase, len: 261; weak similarity to several diverse hydrolases eg. TODF_PSEPU P23133 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase (276 aa), fasta scores; opt: 196 z-score: 344.3 E(): 5.5e-12, 30.7% identity in 270 aa overlap. (261 aa)
SCO5172SCP8.35, possible hydrolase, len: 358 aa; similar to SW:ACOC_ALCEU (EMBL:M66060) Alcaligenes eutrophus dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) AcoC, 373 aa; fasta scores: opt: 224 z-score: 254.0 E(): 1.1e-06; 29.7% identity in 273 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (358 aa)
SCO5165SCP8.28c, possible hydrolase, len: 298 aa; similar to TR:Q9RL59 (EMBL:AL121596) Streptomyces coelicolor putative hydrolase SCF51A.05, 278 aa; fasta scores: opt: 217 z-score: 249.2 E(): 2e-06; 27.0% identity in 267 aa overlap and to SW:THCF_RHOER (EMBL:U95170) Rhodococcus erythropolis non-heme haloperoxidase (EC 1.11.1.-) ThcF, 274 aa; fasta scores: opt: 185 z-score: 213.7 E(): 0.00019l; 29.0% identity in 241 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold and match to Prosite entry PS00120 Lipases, serine active site. (298 aa)
SCO4746SC6G4.24, possible lipase, len: 420 aa; some similar ity to e.g. TR:Q59695 (EMBL:L35343) Pseudomonas putida dihy drolipoamide acetyltransferase (370 aa), fasta scores; opt: 134 z-score: 204.4 E(): 0.00041, 27.0% identity in 352 aa overlap. Contains PS00120 Lipases, serine active site and P fam match to entry PF00561 abhydrolase, alpha/beta hydrolas e fold, score 79.50, E-value 7e-20. Contains possible hydrophobic membrane spanning region. (420 aa)
SCO4479SCD65.22c, possible secreted hydrolase, len: 297 aa; similar to TR:O31386 (EMBL:Y10223) Bradyrhizobium japonicum b-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) PcaD, 260 aa; fasta scores: opt: 188 z-score: 220.7 E(): 8e-05; 32.1% identity in 156 aa overlap. Contains match to Prosite entry PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. Contains possible N-terminal region signal peptide sequence. (297 aa)
SCO0267SCF1.09, possible hydrolase, len: 258 aa; similar to many e.g. TR:O67982 (EMBL:AF003947) 3-oxoadipate enol-lactone hydrolase from Rhodococcus opacus (400 aa) fasta scores; opt: 259, z-score: 300.,1 E(): 2.4e-09, (31.5% identity in 251 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (258 aa)
SCO0145SCJ33.09, possible secreted protein, len: 342 aa. Similar to Streptomyces coelicolor TR:CAB45466 (EMBL; AL079348) hypothetical 33.9 KD protein SC66T3.10C (318 aa), fasta scores opt: 272 z-score: 301.5 E(): 2e-09 34.0% identity in 300 aa overlap. Contains a TTA /leucine codon, possible target for bldA regulation. Contains a possible N-terminal signal sequence. (342 aa)
SCO0135SCJ21.16, unknown, len: 239 aa; similar to two hypothetical proteins from S. coelicolor TR:O86620 (EMBL:AL031155) SC3A7.19 (232 aa), fasta scores; opt: 188 z-score: 222.0 E(): 5.1e-05, 33.6% identity in 238 aa overlap, and TR:Q9ZBN4 (EMBL:AL034492) SC6C5.11 (327 aa), fasta scores; opt: 149 z-score: 176.2 E(): 0.018, 30.0% identity in 203 aa overlapand to TR:Q988L9 (EMBL:AP003009) Rhizobium loti MLR6684 protein, 259 aa; fasta scores: opt: 764 Z-score: 831.4 E(): 1.1e-38; 51.883% identity in 239 aa overlap. (239 aa)
SCO12642SCG18.11, probable hydrolase, len: 316 aa; similar to TR:CAB88827 (EMBL:AL353832) Streptomyces coelicolor putative hydrolase SCE6.23c, 294 aa; fasta scores: opt: 302 z-score: 345.4 E(): 9.3e-12; 31.5% identity in 276 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (316 aa)
SCO1230Putative secreted tripeptidylaminopeptidase; Cleaves tripeptides from the N-termini of proteins. Does not cleave mono- or dipeptides, or N-terminally blocked peptides (By similarity); Belongs to the peptidase S33 family. (541 aa)
SCO10972SCG4.13, probable hydrolase, len: 292 aa; similar to TR:O52866 (EMBL:AJ224332) Corynebacterium sp. soluble epoxide hydrolase (EC 3.3.2.3) Ceh, 285 aa; fasta scores: opt: 601 z-score: 728.8 E(): 0; 35.8% identity in 288 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (292 aa)
SCO0939SCM10.27c, probable hydrolase, len: 287 aa; similar to TR:CAB56657 (EMBL:AL121596) Streptomyces coelicolor putative hydrolase SCF51A.05, 278 aa; fasta scores: opt: 325 z-score: 381.1 E(): 7.7e-14; 32.9% identity in 283 aa overlap and to SW:PRXC_STRAU (EMBL:AF031242) Streptomyces aureofaciens non-heme chloroperoxidase (EC 1.11.1.10) CpoT, 278 aa; fasta scores: opt: 239 z-score: 282.3 E(): 2.5e-08; 30.4% identity in 253 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (287 aa)
SCO0899Putative hydrolase; SCM1.32, possible hydrolase, len: 298 aa. Similar to many including: Moraxella sp. SW:DEH1_MORSP (EMBL:D90422:) haloacetate dehalogenase H-1 (EC 3.8.1.3) (294 aa), fasta scores opt: 669 z-score: 782.5 E():0 39.2% identity in 296 aa overlap and Streptomyces coelicolor TR:O86546 (EMBL:AL031350) putative hydrolase SC1F2.09C (309 aa), fasta scores opt: 336 z-score: 396.1 E(): 1e-14 31.1% identity in 305 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (298 aa)
SCO0878SCM1.11, possible hydrolase, len: 292 aa. Highly similar to several including: Streptomyces peucetius TR:Q54809(EMBL:L40425) 10-carbomethoxy-13-deoxycarminomycin esterase (298 aa), fasta scores opt: 670 z-score: 757.9 E():0 40.3% identity in 288 aa overlap and Streptomyces purpurascens TR:Q54528(EMBL:U10405:) possible C-C hydrolase, RdmC (298 aa) fasta scores opt: 709 z-score: 801.6 E():0 41.2% identity in 289 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (292 aa)
SCO4395SCD10.27, possible hydrolase, len: 352 aa; similar to TR:Q9RCX1 (EMBL:AL133469) Streptomyces coelicolor putative hydrolase SCM10.27c, 287 aa; fasta scores: opt: 290 z-score: 298.8 E(): 3.6e-09; 28.5% identity in 277 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (352 aa)
SCO4392SCD10.24, possible esterase, len: 241 aa; similar to TR:Q9RBI4 (EMBL:AF150928) Acinetobacter sp. ADP1 alkyl salicylate esterase SalE, 239 aa; fasta scores: opt: 360 z-score: 411.1 E(): 2e-15; 28.6% identity in 241 aa overlap. (241 aa)
SCO4160SCD84.27, possible hydrolase, len: 278 aa; similar to TR:AAF25687 (EMBL:AF218823) Thermomonospora fusca putative dienelactone hydrolase DlhA, 265 aa; fasta scores: opt: 786 z-score: 885.1 E(): 0; 50.0% identity in 262 aa overlap. (278 aa)
SCO0461SCF76.01, possible hydrolase, partial CDS, len: >228 aa. Similar to several hypothetical proteins e.g. from Saccharomyces cerevisiae SW:YN93_YEAST (EMBLL:Z71679) (290 aa), fasta scores opt: 609 z-score: 749.0 E():0 42.4% identity in 229 aa overlap. Also weakly similar to Xanthobacter autotrophicus SW:HALO_XANAU (EMBL:M26950) haloalkane dehalogenase (EC 3.8.1.5) (310 aa), fasta scores opt: 151 z-score: 190.4 E():0.003 22.9% identity in 231 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold; SCF51A.39, possible hydrolase, partial CDS, len: >113 aa. [...] (289 aa)
SCO0427SCF51A.05, possible hydrolase, len: 278 aa. Similar to many e.g. Pseudomonas fluorescens SW:PRXC_PSEFL (EMBL:AF031153) non-heme chloroperoxidase (EC 1.11.1.10) (chloride peroxidase), fasta scores opt: 243 z-score: 282.1 E(): 2.4e-08 28.4% identity in 275 aa overlap and many putative hydrolases: Streptomyces coelicolor TR:CAB44393 (EMBL; AL078610) putative hydrolase SCH35.34C (269 aa), fasta scores opt: 259 z-score: 300.1 E(): 2.3e-09 29.7% identity in 269 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (278 aa)
SCO7205Putative hydrolase; SC2H12.04, possible hydrolase, len: 286 aa. Highly similar to many including: Moraxella sp. SW:DEH1_MORSP(EMBL:D90422) haloacetate dehalogenase H-1 (EC 3.8.1.3) (294 aa), fasta scores opt: 556 z-score: 678.4 E(): 2.6e-30 35.6% identity in 292 aa overlap and Streptomyces coelicolor: TR:Q9RD12(EMBL:AL133422) putative hydrolase, SCM1.32 (298 aa), fasta scores opt: 653 z-score: 795.7 E(): 0 42.2% identity in 287 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (286 aa)
SCO7245Putative hydrolase; SC7A12.12, possible hydrolase, len: 301 aa. Similar to Lactobacillus helveticus SW:PIP_LACHE(EMBL:Z56283) proline iminopeptidase (EC 3.4.11.5) (294 aa), fasta scores opt: 254 z-score: 284.0 E(): 2.4e-08 27.5% identity in 262 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (301 aa)
SCO3690SCH35.34c, possible hydrolase, len: 269 aa; similar to TR: O07015 (EMBL:Z94043) hypothetical protein from Bacillus subtilis (269 aa) fasta scores; opt: 907, z-score: 1096.7, E(): 0, (47.7% identity in 262 aa overlap). Also weakly similar to TR:BAA34263 (EMBL:AB014348) 2-hydroxy-6-oxo-6-phenylehexa-2,4-dienoate hydrolase from Rhodococcus erythropolis TA421 (297 aa) fasta scores; opt: 227, z-score: 278.9, E(): 3.3e-08, (27.1% identity in 277 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (269 aa)
SCO3954SCD78.21c, putative oxidoreductase, len: 584 aa; N-terminal region similar to Y00P_MYCTU (EMBL:Z70283) putative oxidoreductase from Mycobacterium tuberculosis (650 aa), fasta scores; opt: 1457, z-score: 840.1, E(): 0, 41.0% identity in 652 aa overlap. Contains PS00061 short chain dehydrogenases /reductases family signature. (585 aa)
SCO7256SC5H1.36, probable protease (putative secreted protein), len: 543 aa; similar to many e.g. TR:Q54398 (EMBL:L42758), SlpD, Streptomyces lividans protease, (539 aa), fasta scores; opt: 697 z-score: 769.7 E(): 0,35.8% identity in 545 aa overlap. Similar to other S.coelicolor proteases e.g. SlpD, SCH5.02c (EMBL:AL03563) proteinase (539 aa) (35.8% identity in 545 aa overlap). Contains possible N-terminal signal sequence. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold, score 55.00, E-value 1.6e-12. (543 aa)
SCO7440SC6D11.36c, possible hydrolase, len: 314 aa. Similar to several including Moraxella sp. SW:DEH1_MORSP (EMBL:D90422) haloacetate dehalogenase H-1 (EC 3.8.1.3) (294 aa). fasta scores opt: 356 z-score: 414.9 E(): 1.1e-15 27.9% identity in 297 aa overlap and Streptomyces coelicolor TR:O86546 (EMBL:AL031350) putative hydrolase, SC1F2.09C (309 aa), fasta scores opt: 498 z-score: 577.2 E(): 9.9e-25 35.2% identity in 307 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (314 aa)
SCO3574SCH17.08c, possible epoxide hydrolase, len: 354 aa; similar to eukaryotic epoxide hydrolases e.g. TR:Q42566 (EMBL:D16628), atseH, Arabidopsis thaliana epoxide hydrolase (321 aa), fasta scores; opt: 501 z-score: 542.6 E(): 6.8e-23, 37.7% identity in 332 aa overlap. Similar to others from S.coelicolor e.g. SCH5.29 (EMBL:AL035636) putative hydrolase (324 aa) (33.6% identity in 348 aa overlap). Alternative start codons are present at codons 6 and 30, but these have no apparent RBS. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (354 aa)
SCO7609SC2H2.07c, possible esterase, len: 228 aa; low similarity to TR:Q9K3V2 (EMBL:AL359988) Streptomyces coelicolor putative esterase SCD10.24, 241 aa; fasta scores: opt: 169 z-score: 195.6 E(): 0.0023; 28.0% identity in 236 aa overlap. (228 aa)
SCO7777SC5E9.25c, possible hydrolase, len: 309aa; weakly similar to many eg. TR:O69356 (EMBL:D88016) 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus erythropolis (281 aa) fasta scores; opt: 206, z-score: 247.2, E(): 2.7e-06, 26.3% identity in 281 aa overlap. (309 aa)
SCO6479SC9C7.15c, probable secreted peptidase, len: 529aa; similar to many eg. TR:Q54410(EMBL:L27466) secreted tripeptidyl aminopeptidase from Streptomyces lividans 66 (537 aa) fasta scores; opt: 1362, z-score: 1170.0, E(): 0, (43.2% identity in 526 aa overlap), has probable N-terminal signal sequence. Contains Pfam match to entry PF00561 abhydrolase, alpha /beta hydrolase fold. Also similar to TR:O69831 (EMBL:AL023517) from Streptomyces coelicolor cosmid 1B5 (543 aa) fasta scores; opt: 1205, z-score: 1105.7, E(): 0, (42.3% identity in 541 aa overlap). (529 aa)
SCO6351Hypothetical protein SC3A7.19; SC3A7.19, unknown, len: 232 aa. (232 aa)
SCO6339SC3A7.07, probable 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase, len: 449 aa; Similar in N- and C- termini to Rhodococcus opacus TR:G2935027 (EMBL:EMBL; AF003947) 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase (400 aa), fasta scores; opt: 551 z-score: 916.0 E(): 0, 35.2% identity in 435 aa overlap. N-terminus (to 250aa) is similar to e.g. Acinetobacter calcoaceticus TR:Q59093 (EMBL:L05770) beta-ketoadipate enol-lactone hydrolase (266 aa), fasta scores; opt: 445 z-score: 470.5 E(): 5.9e-19, 30.3% identity in 244 aa overlap. C-terminu [...] (449 aa)
SCO6277SC1G7.03, possible epoxide hydrolase, len: 286 aa; similar to TR:Q42566 (EMBL:D16628) Arabidopsis thaliana epoxide hydrolase (EC 3.3.2.3) Seh or F18A8.11, 321 aa; fasta scores: opt: 351 Z-score: 406.4 bits: 83.3 E(): 4.8e-15; 29.560% identity in 318 aa overlap. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. (286 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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