(3 nodes) Myo-inositol-1-phosphate synthase network (Streptomyces coelicolor)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	SCO3899	SCH24.21c, conserved hypothetical protein, len: 360 aa; unknown function, similar to e.g. TR:P71703 (EMBL:Z80775) Mycobacterium tuberculosis hypothetical protein (367 aa), fasta scores; opt: 1790 z-score: 2136.2 E(): 0, 78.5% identity in 353 aa overlap. C-terminal half shows weak similarity with a region of SW:INO1_CANAL (EMBL:L22737), Ino1, Candida albicans myo-inositol-1-phosphate synthase (520 aa) (26.3% identity in 251 aa overlap) and with TR:O69948 (EMBL:AL023862) S.coelicolor probable secreted protein (417 aa) (25.2% identity in 226 aa overlap). (360 aa)
	SCO3243	SCE29.12c, possible myo-inositol phosphate synthase, len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) from Streptomyces coelicolor (417 aa) fasta scores; opt: 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa overlap) and SW:INO1_CITPA myo-inositol phosphate synthase from Citrus paradisi (grapefruit) fasta scores; opt: 323, z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa overlap). (388 aa)
	SCO6573	SC3F9.08, probable secreted protein, len: 417 aa; some similarity to many eukaryotic myo-inositol-1-phosphate synthases e.g. INO1_SPIPO (510 aa), fasta scores; opt: 159 z-score: 190.1 E(): 0.0022, 28.1% identity in 423 aa overlap, and to Archaeoglobus fulgidus TR:O28480 (EMBL:AE000979) AF1794 (392 aa), fasta scores; opt: 546 z-score: 713.5 E(): 1.6e-32, 37.0% identity in 397 aa overlap. Contains possible N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (417 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO3243	SCO3899	gene:17760861	gene:17761526	SCE29.12c, possible myo-inositol phosphate synthase, len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) from Streptomyces coelicolor (417 aa) fasta scores; opt: 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa overlap) and SW:INO1_CITPA myo-inositol phosphate synthase from Citrus paradisi (grapefruit) fasta scores; opt: 323, z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa overlap).	SCH24.21c, conserved hypothetical protein, len: 360 aa; unknown function, similar to e.g. TR:P71703 (EMBL:Z80775) Mycobacterium tuberculosis hypothetical protein (367 aa), fasta scores; opt: 1790 z-score: 2136.2 E(): 0, 78.5% identity in 353 aa overlap. C-terminal half shows weak similarity with a region of SW:INO1_CANAL (EMBL:L22737), Ino1, Candida albicans myo-inositol-1-phosphate synthase (520 aa) (26.3% identity in 251 aa overlap) and with TR:O69948 (EMBL:AL023862) S.coelicolor probable secreted protein (417 aa) (25.2% identity in 226 aa overlap).	0.919
SCO3243	SCO6573	gene:17760861	gene:17764230	SCE29.12c, possible myo-inositol phosphate synthase, len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) from Streptomyces coelicolor (417 aa) fasta scores; opt: 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa overlap) and SW:INO1_CITPA myo-inositol phosphate synthase from Citrus paradisi (grapefruit) fasta scores; opt: 323, z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa overlap).	SC3F9.08, probable secreted protein, len: 417 aa; some similarity to many eukaryotic myo-inositol-1-phosphate synthases e.g. INO1_SPIPO (510 aa), fasta scores; opt: 159 z-score: 190.1 E(): 0.0022, 28.1% identity in 423 aa overlap, and to Archaeoglobus fulgidus TR:O28480 (EMBL:AE000979) AF1794 (392 aa), fasta scores; opt: 546 z-score: 713.5 E(): 1.6e-32, 37.0% identity in 397 aa overlap. Contains possible N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.	0.903
SCO3899	SCO3243	gene:17761526	gene:17760861	SCH24.21c, conserved hypothetical protein, len: 360 aa; unknown function, similar to e.g. TR:P71703 (EMBL:Z80775) Mycobacterium tuberculosis hypothetical protein (367 aa), fasta scores; opt: 1790 z-score: 2136.2 E(): 0, 78.5% identity in 353 aa overlap. C-terminal half shows weak similarity with a region of SW:INO1_CANAL (EMBL:L22737), Ino1, Candida albicans myo-inositol-1-phosphate synthase (520 aa) (26.3% identity in 251 aa overlap) and with TR:O69948 (EMBL:AL023862) S.coelicolor probable secreted protein (417 aa) (25.2% identity in 226 aa overlap).	SCE29.12c, possible myo-inositol phosphate synthase, len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) from Streptomyces coelicolor (417 aa) fasta scores; opt: 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa overlap) and SW:INO1_CITPA myo-inositol phosphate synthase from Citrus paradisi (grapefruit) fasta scores; opt: 323, z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa overlap).	0.919
SCO3899	SCO6573	gene:17761526	gene:17764230	SCH24.21c, conserved hypothetical protein, len: 360 aa; unknown function, similar to e.g. TR:P71703 (EMBL:Z80775) Mycobacterium tuberculosis hypothetical protein (367 aa), fasta scores; opt: 1790 z-score: 2136.2 E(): 0, 78.5% identity in 353 aa overlap. C-terminal half shows weak similarity with a region of SW:INO1_CANAL (EMBL:L22737), Ino1, Candida albicans myo-inositol-1-phosphate synthase (520 aa) (26.3% identity in 251 aa overlap) and with TR:O69948 (EMBL:AL023862) S.coelicolor probable secreted protein (417 aa) (25.2% identity in 226 aa overlap).	SC3F9.08, probable secreted protein, len: 417 aa; some similarity to many eukaryotic myo-inositol-1-phosphate synthases e.g. INO1_SPIPO (510 aa), fasta scores; opt: 159 z-score: 190.1 E(): 0.0022, 28.1% identity in 423 aa overlap, and to Archaeoglobus fulgidus TR:O28480 (EMBL:AE000979) AF1794 (392 aa), fasta scores; opt: 546 z-score: 713.5 E(): 1.6e-32, 37.0% identity in 397 aa overlap. Contains possible N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.	0.927
SCO6573	SCO3243	gene:17764230	gene:17760861	SC3F9.08, probable secreted protein, len: 417 aa; some similarity to many eukaryotic myo-inositol-1-phosphate synthases e.g. INO1_SPIPO (510 aa), fasta scores; opt: 159 z-score: 190.1 E(): 0.0022, 28.1% identity in 423 aa overlap, and to Archaeoglobus fulgidus TR:O28480 (EMBL:AE000979) AF1794 (392 aa), fasta scores; opt: 546 z-score: 713.5 E(): 1.6e-32, 37.0% identity in 397 aa overlap. Contains possible N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.	SCE29.12c, possible myo-inositol phosphate synthase, len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) from Streptomyces coelicolor (417 aa) fasta scores; opt: 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa overlap) and SW:INO1_CITPA myo-inositol phosphate synthase from Citrus paradisi (grapefruit) fasta scores; opt: 323, z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa overlap).	0.903
SCO6573	SCO3899	gene:17764230	gene:17761526	SC3F9.08, probable secreted protein, len: 417 aa; some similarity to many eukaryotic myo-inositol-1-phosphate synthases e.g. INO1_SPIPO (510 aa), fasta scores; opt: 159 z-score: 190.1 E(): 0.0022, 28.1% identity in 423 aa overlap, and to Archaeoglobus fulgidus TR:O28480 (EMBL:AE000979) AF1794 (392 aa), fasta scores; opt: 546 z-score: 713.5 E(): 1.6e-32, 37.0% identity in 397 aa overlap. Contains possible N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.	SCH24.21c, conserved hypothetical protein, len: 360 aa; unknown function, similar to e.g. TR:P71703 (EMBL:Z80775) Mycobacterium tuberculosis hypothetical protein (367 aa), fasta scores; opt: 1790 z-score: 2136.2 E(): 0, 78.5% identity in 353 aa overlap. C-terminal half shows weak similarity with a region of SW:INO1_CANAL (EMBL:L22737), Ino1, Candida albicans myo-inositol-1-phosphate synthase (520 aa) (26.3% identity in 251 aa overlap) and with TR:O69948 (EMBL:AL023862) S.coelicolor probable secreted protein (417 aa) (25.2% identity in 226 aa overlap).	0.927