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SCO2941 SCO2941 SCO2222 SCO2222 SCO1134 SCO1134 SCO0922 SCO0922 SCO5106 SCO5106 SCO6171 SCO6171 SCO7475 SCO7475 SCO4971 SCO4971 SCO6678 SCO6678 SCO0689 SCO0689
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
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Your Input:
SCO2941Conserved hypothetical protein SCE56.05c; SCE56.05c, unknown, len: 773 aa; similar to C-terminal region of TR:Q9VYQ2 (EMBL:AE003488) Drosophila melanogaster CG2779 protein, 1612 aa; fasta scores: opt: 651 Z-score: 464.7 E(): 3e-18; 31.405% identity in 847 aa overlap. High content in proline, glycine and alanine. Contains Pfam matches to entries PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains and PF01799 fer2_2, [2Fe-2S] binding domain and match to Prosite entry PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. (773 aa)
SCO2222SC10B7.17, probable iron-sulfur oxidoreductase (putative secreted protein), len: 364 aa; similar to TR:O88034 (EMBL:AL031107) Streptomyces coelicolor iron-sulfur oxidoreductase beta subunit SC5A7.28c, 313 aa; fasta scores: opt: 1032 z-score: 1177.8 E(): 0; 55.2% identity in 310 aa overlap and to SW:POBB_PSEPS (EMBL:X78823) Pseudomonas pseudoalcaligenes phenoxybenzoate dioxygenase beta subunit (EC 1.-.-.-.) PobB, 319 aa; fasta scores: opt: 680 z-score: 777.9 E(): 0; 40.8% identity in 314 aa overlap. Contains two matches to Pfam entries Pfam match to entry PF00175 oxidored_fad, Oxidoredu [...] (364 aa)
SCO11342SCG38.27c, probable oxidoreductase, iron-sulphur binding subunit, len: 200 aa; similar to TR:Q52589 (EMBL:X77931) Pseudomonas thermocarboxydovorans carbon monoxide oxygenase [cytochrome B-561], small chain (EC 1.2.2.4) CutC, 163 aa; fasta scores: opt: 405 z-score: 478.3 E(): 3.4e-19; 45.6% identity in 169 aa overlap and to TR:Q9RK27 (EMBL:AL132856) Streptomyces coelicolor putative oxidoreductase, iron-sulphur binding subunit StF15.10, 211 aa; fasta scores: opt: 729 z-score: 804.0 E(): 0; 62.3% identity in 175 aa overlap. Contains Pfam matches to entries PF00111 fer2, 2Fe-2S iron-sulfu [...] (200 aa)
SCO0922SCM10.10c, probable reductase iron-sulfur protein, len: 248 aa; similar to SW:FRDB_MYCTU (EMBL:Z74020) Mycobacterium tuberculosis fumarate reductase iron-sulfur protein (EC 1.3.99.1) FrdB, 247 aa; fasta scores: opt: 288 z-score: 321.7 E(): 1.6e-10; 28.9% identity in 239 aa overlap. Contains Pfam matches to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains and entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and to Prosite entries PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature and PS00198 4Fe-4S ferredoxins, iron-sulfu [...] (248 aa)
SCO5106SCBAC31E11.02c, shdB2, probable succinate dehydrogenase iron-sulfur subunit, len: 259 aa; highly similar to TR:AAK44479 (EMBL:AE006934) Mycobacterium tuberculosis ferredoxin, 2Fe-2S MT0261, 248 aa; fasta scores: opt: 1355 Z-score: 1588.1 bits: 301.4 E(): 7.7e-81; 74.900% identity in 251 aa overlap and to SW:DHSB_BACSU (EMBL:M13470) Bacillus subtilis succinate dehydrogenase iron-sulfur protein SdhB, 252 aa; fasta scores: opt: 365 Z-score: 434.1 bits: 87.9 E(): 1.4e-16; 30.603% identity in 232 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains. (259 aa)
SCO6171Putative oxidoreductase; SC6C5.07, probable iron-sulphur binding oxidoreductase subunit, len: 196aa; similar to many eg. TR:P95635 (EMBL:U65440) 4-hydroxybenzoyl-CoA reductase from Rhodopseudomonas palustris (163 aa) fasta scores; opt: 288, z-score: 720.8, E(): 7.4e-33, (42.2% identity in 187 aa overlap) and TR:P72223 (EMBL:X98131) quinoline 2-oxidoreductase from Pseudomonas putida (168 aa) fasta scores; opt: 264, z-score: 703.7, E(): 6.6e-32, (40.4% identity in 198 aa overlap). Contains PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. (196 aa)
SCO7475SCBAC17A6.08, possible phenylacetic acid degradation NADH oxidoreductase PaaE, len: 368 aa; similar to many e.g. SW:P76081 (PAAE_ECOLI) probable phenylacetic acid degradation NADH oxidoreductase PaaE from Escherichia coli (356 aa) fasta scores; opt: 871, Z-score: 943.6, 39.943% identity (40.870% ungapped) in 353 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains; Pfam match to entry PF00175 NAD_binding, Oxidoreductase FAD/NAD-binding domain; Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain and Prosite match to P [...] (368 aa)
SCO49712SCK31.31, possible dehydrogenase, len: 497 aa; similar to N-terminal domain of SW:XDH_MOUSE (EMBL:X75129) Mus musculus xanthine dehydrogenase/oxidase Xdh, 1335 aa; fasta scores: opt: 345 z-score: 361.7 E(): 1.3e-12 31.5% identity in 483 aa overlap and to TR:O54050 (EMBL:AJ001013) Rhodobacter capsulatus xanthine dehydrogenase (EC 1.1.1.204) XdhA, 462 aa; fasta scores: opt: 631 z-score: 669.1 E(): 9.8e-30; 38.2% identity in 495 aa overlap. Contains Pfam matches to entries PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains, PF01799 fer2_2, [2Fe-2S] binding domain and PF00941 dehydr [...] (497 aa)
SCO6678SC5A7.28c, probable iron-sulfur oxidoreductase beta subunit, len: 313 aa; similar to many e.g. POBB_PSEPS phenoxybenzoate dioxygenase beta subunit (Pseudomonas pseudoalcaligenes) (319 aa), fasta scores; opt: 824 z-score: 993.1 E(): 0, 45.9% identity in 303 aa overlap. C-terminus is a 2Fe-2S ferredoxin domain similar to e.g. FERV_ANAVA ferredoxin, vegetative (Anabaena variabilis) (98 aa), fasta scores; opt: 187 z-score: 222.4 E(): 3.8e-05, 38.2% identity in 68 aa overlap. Contains PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature and Pfam match to entry PF00111 fer2, 2Fe- [...] (313 aa)
SCO0689SCF15.10, possible oxidoreductase, iron-sulphur binding subunit, len: 187 aa. Similar to many multipartite proteins including: the small subunit of quinoline 2-oxidoreductase from Pseudomonas putida TR:P72223(EMBL:X98131) QorS (168 aa), fasta scores opt: 371 z-score: 438.8 E(): 4.6e-17 44.7% identity in 170 aa overlap and Acetobacter europaeus TR:O30328(EMBL:Y08696) aldehyde dehydrogenase subunit III precursor (157 aa), fasta scores opt: 309 z-score: 367.9 E(): 4e-13 39.3% identity in 163 aa overlap. Also similar to the N-terminal iron-sulphur binding domain of Rhodobacter capsulatus ( [...] (211 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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