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SCO7572 SCO7572 SCO0816 SCO0816 SCO0922 SCO0922 SCO1977 SCO1977 SCO2025 SCO2025 SCO3673 SCO3673 SCO4855 SCO4855 SCO5106 SCO5106
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO7572SC5F1.26, possible oxidoreductase, len: 998 aa; similar to TR:Q9KKW5 (EMBL:AE004425) Vibrio cholerae oxidoreductase/iron-sulfur cluster-binding protein VCA0985, 959 aa; fasta scores: opt: 1999 z-score: 2189.0 E(): 0; 35.3% identity in 966 aa overlap. Contains Pfam matches to entries PF01565 FAD_binding_4, FAD binding domain and PF00037 fer4, 4Fe-4S binding domain and matches to Prosite entries PS00422 Granins signature 1 and PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. (998 aa)
SCO0816SCF43A.06, conserved possible iron-sulfur protein, len: 492 aa; similar to several putative iron-sulfur proteins e.g. SW:YKGF_ECOLI (EMBL:AE000137) Escherichia coli hypothetical protein (475 aa), fasta scores; opt: 1148 z-score: 1249.5 E(): 0, 39.7% identity in 481 aa overlap, which contains 2 putative 4Fe-4S centres. Contains PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. (492 aa)
SCO0922SCM10.10c, probable reductase iron-sulfur protein, len: 248 aa; similar to SW:FRDB_MYCTU (EMBL:Z74020) Mycobacterium tuberculosis fumarate reductase iron-sulfur protein (EC 1.3.99.1) FrdB, 247 aa; fasta scores: opt: 288 z-score: 321.7 E(): 1.6e-10; 28.9% identity in 239 aa overlap. Contains Pfam matches to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains and entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and to Prosite entries PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature and PS00198 4Fe-4S ferredoxins, iron-sulfu [...] (248 aa)
SCO1977SC3C9.12c, possible glutamate synthase small subunit, len: 496 aa; similar to C-terminal part of SW:GLSN_MEDSA (EMBL:L01660) Medicago sativa glutamate synthase [NADH], chloroplast precursor (EC 1.4.1.14) (NADH-GOGAT) GlsN, 2194 aa; fasta scores: opt: 1473 Z-score: 1543.9 bits: 297.3 E(): 2.2e-78; 47.551% identity in 490 aa overlap and to TR:Q9S2Z0 (EMBL:AL109849) Streptomyces coelicolor putative glutamate synthase small subunit SC3A3.03c, 487 aa; fasta scores: opt: 2145 Z-score: 2259.1 bits: 427.5 E(): 3.2e-118; 66.398% identity in 497 aa overlap. Contains Pfam match to entry PF00070 p [...] (496 aa)
SCO2025SC3A3.03c, gltD, probable glutamate synthase small subunit, len: 487 aa; similar to bacterial glutamate synthases e.g. TR:Q51584 (EMBL:D85230), gltD, Plectonema boryanum small subunit of NADH-dependent glutamate synthase (492 aa), fasta scores; opt: 1295 z-score: 1405.0 E(): 0, 51.2% identity in 500 aa overlap. Also similar to part of eukaryotic glutamate synthases e.g. SW:GLSN_MEDSA (EMBL:L01660) Medicago sativa (Alfalfa) Glutamate synthase [NADH] precursor (2194 aa) (49.1% identity in 489 aa overlap). Contains Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulf [...] (487 aa)
SCO3673SCH35.51c, probable iron-sulphur-binding reductase, len: 433 aa; similar to many eg. TR:P96797 (EMBL:Y09870) heterodisulphide reductase from Methanosarcina barkeri (409 aa) fasta scores; opt: 427, z-score: 463.9, E(): 1.6e-18, (28.9% identity in 443 aa overlap). Contains 2 Pfam matches to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and 2 Prosite matches to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. Contains also possible hydrophobic membrane spanning regions. (760 aa)
SCO4855SC5G8.23c, dhsB, probable succinate dehydrogenase iron-sulfur subunit, len: 257aa; strongly similar to many eg. SW:P07014 (DHSB_ECOLI) succinate dehydrogenase iron-sulfur protein from Escherichia coli (238 aa) fasta scores; opt: 729, z-score: 839.1, E(): 0, 44.3% identity in 237 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains, Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and Prosite match to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature; Belongs to the succinate [...] (257 aa)
SCO5106SCBAC31E11.02c, shdB2, probable succinate dehydrogenase iron-sulfur subunit, len: 259 aa; highly similar to TR:AAK44479 (EMBL:AE006934) Mycobacterium tuberculosis ferredoxin, 2Fe-2S MT0261, 248 aa; fasta scores: opt: 1355 Z-score: 1588.1 bits: 301.4 E(): 7.7e-81; 74.900% identity in 251 aa overlap and to SW:DHSB_BACSU (EMBL:M13470) Bacillus subtilis succinate dehydrogenase iron-sulfur protein SdhB, 252 aa; fasta scores: opt: 365 Z-score: 434.1 bits: 87.9 E(): 1.4e-16; 30.603% identity in 232 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains. (259 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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