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| | SCO6802 | SC1A2.11, possible DNA-binding protein, len: 192 aa. Similar to Streptomyces coelicolor TR:Q9X7W5 (EMBL:AL049485) putative DNA-binding protein, SC6A5.19 (204 aa), fasta scores opt: 213 z-score: 254.6 E(): 9e-07 30.9% identity in 178 aa overlap. Contains a Pfam match to entry PF01381 HTH_3, Helix-turn-helix with the putative helix-turn-helix motif situated between residues 28..49 (+7.43 SD). (192 aa) |
| | SCO5427 | Hypothetical protein SC6A11.03c; SC6A11.03c, unknown, len: 237 aa; no significant database similarities. (237 aa) |
| | SCO5611 | SC2E1.28, possible prophage transcriptional regulator, len: 71 aa; similar to the N-terminus of many e.g. TR:Q37946 Salmonella typhimurium bacteriophage L repressor protein C2 (220 aa), fasta scores; opt: 127 z-score: 227.1 E():2e-05, 45.7% identity in 46 aa overlap. Contains probable helix-turn-helix motif at aa 21 to 42 (Score 1829, +5.42 SD). (71 aa) |
| | SCO5614 | SC2E1.31, possible prophage transcriptional regulator, len: 63 aa; similar to the N-terminus of many e.g. TR:E264367 (EMBL:X87420) Salmonella typhimurium bacteriophage ES18 gene C2 (216 aa), fasta scores; opt: 133 z-score: 207.9E(): 0.00024, 35.8% identity in 53 aa overlap. Contains probable helix-turn-helix motif at aa 17 to 38 (Score 1786, +5.27 SD). (63 aa) |
| | SCO5692 | SC5H4.16c, probable transcriptional regulator, len: 337 aa; similar to SW:CELR_THEFU (EMBL:AF086819) Thermomonospora fusca transcription regulator CelR, 340 aa; fasta scores: opt: 440 z-score: 531.7 E(): 3.7e-22; 31.6% identity in 339 aa overlap. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family and PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family and match to Prosite entry PS00356 Bacterial regulatory proteins, lacI family signature. Contains also possible helix-turn-helix motif at residues 2..23 [...] (337 aa) |
| | SCO5751 | SC7C7.06, putative membrane protein, len: 287 aa. Contains possible hydrophobic membrane spanning region. (287 aa) |
| | SCO7140 | SC9A4.02, probable DNA-binding protein, len: 276 aa; highly similar to TR:Q9S1Q8 (EMBL:AL109972) Streptomyces coelicolor putative DNA-binding protein SCJ9A.12c, 279 aa; fasta scores: opt: 1046 z-score: 1203.5 E(): 0; 59.1% identity in 274 aa overlap. Contains a possible helix-turn-helix motif at residues 36..57 (+3.89 SD). (276 aa) |
| | SCO7027 | SC1H10.16c, probable LacI-family transcriptional regulator, len: 339 aa. Highly similar to Streptomyces lividans TR:Q9ZI18 (EMBL:AF043654) LacI-GalR family regulatory protein, BxlR (338 aa), fasta scores opt: 2136 z-score: 2395.5 E(): 0 96.5% identity in 340 aa overlap and Escherichia coli SW:CYTR_ECOLI (EMBL:X03683) transcriptional repressor, CytR (341 aa), fasta scores opt: 553 z-score: 625.0 E(): 2.2e-27 32.7% identity in 330 aa overlap. Also highly similar to Streptomyces coelicolor TR:O86795(EMBL:AL031317) putative transcriptional regulator, SC6G4.32 (355 aa), fasta scores opt: 13 [...] (339 aa) |
| | SCO7016 | SC1H10.05c, possible LacI-family transcriptional regulatory protein, len: 336 aa. Identical to Streptomyces lividans protein encoded on the 1 kb TR: Q57094(EMBL:U22894) left direct repeat sequence contained within the amplifiable AUD1 element (336 aa), fasta scores opt: 2173 z-score: 2549.4 E():0 99.4% identity in 336 aa overlap. Also highly similar to Streptomyces coelicolor SW:MALR_STRCO (EMBL:Y07706) maltose operon transcriptional repressor, MalR or SC10B7.03c (344 aa), fasta scores opt: 1137 z-score: 1336.5 E():0 53.7% identity in 341 aa overlap. This gene is duplicated on this cos [...] (336 aa) |
| | SCO5755 | Hypothetical protein SC7C7.10; SC7C7.10, unknown, len: 126 aa; highly similar to M. tuberculosis TR:O33287 (EMBL:AL008967) possible transcriptional regulator MTV002.10C (Rv2745c) (112 aa), fasta scores; opt: 300 z-score: 454.0 E(): 4.7e-18, 60.5% identity in 86 aa overlap. (126 aa) |
| | SCO5998 | Putative UDP-N-acetylglucosamine transferase; SCBAC1C11.01c, murA2, possible bifunctional protein (fragment), len: >138 aa; N-terminal domain similar to TR:Q9X153 (EMBL:AE001787) Thermotoga maritima lacI-family transcriptional regulator, putative TM1330, 111 aa; fasta scores: opt: 139 z-score: 193.0 E(): 0.0033; 39.4% identity in 66 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and possible helix-turn-helix motif at residues 22..43 (+7.45 SD) and C-terminal domain similar to TR:Q9PJT7 (EMBL:AE002342) Chlamydia muridarum UDP-N-acetylglucosamine 1-carboxyvinylt [...] (509 aa) |
| | SCO6003 | SCBAC1C11.06c, possible DNA-binding protein, len: 286 aa; similar to TR:CAC01466 (EMBL:AL391014) Streptomyces coelicolor putative DNA-binding protein 2SCG1.17, 286 aa; fasta scores: opt: 528 z-score: 639.9 E(): 4.2e-28; 37.4% identity in 281 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and possible helix-turn-helix motif at residues 27..48 (+4.04 SD). (286 aa) |
| | SCO6129 | SC9B2.16c, possible DNA-binding protein, len: 303aa; similar to proteins of unknown function egs. TR:O86676 (EMBL:AL031371) hypothetical 30.7 kD protein from Streptomyces coelicolor (277 aa) fasta scores; opt: 552, z-score: 663.3, E(): 1.2e-29, (37.7% identity in 257 aa overlap) and SW:ENTD_SALTY EntD, a protein from Salmonella typhimurium with undefined involvement in enterobactin biosynthesis (232 aa) fasta scores; opt: 102, z-score: 129.9, E(): 6, (26.7% identity in 191 aa overlap). Contains a probable helix-turn-helix (+3.37 SD) at residues 60 to 81. (303 aa) |
| | SCO6233 | SC2H4.15, probable transcriptional regulator, len: 342 aa; similar to many members of the lacI family e.g. CCPA_BACME glucose-resistance amylase regulator (Bacillus megaterium) (332 aa), fasta scores; opt: 448 z-score: 548.6 E(): 2.6e-23, 29.8% identity in 336 aa overlap. Contains helix-turn-helix motif from aa 9-30 (Score 1778, +5.24 SD) and Pfam matches to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, score 30.40, E-value 4.7e-07 and to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, score 44.00, E-value 3.4e-09. (342 aa) |
| | SCO7014 | SC1H10.03c, probable LacI-family transcriptional regulatory protein, len: 337 aa. Identical to Streptomyces lividans protein encoded on the 1 kb TR:Q57276 (EMBL:X65466) right direct repeat sequence contained within the amplifiable AUD1 element (337 aa), fasta scores opt: 2188 z-score: 2534.7 E():0 99.7% identity in 337 aa overlap. Also highly similar to Streptomyces coelicolor SW:MALR_STRCO (EMBL:Y07706) maltose operon transcriptional repressor, MalR or SC10B7.03c (344 aa), fasta scores opt: 1114 z-score: 1293.5 E():0 53.3% identity in 336 aa overlap. This gene is duplicated on this co [...] (337 aa) |
| | SCO6986 | SC8F11.12, possible DNA-binding protein, len: 348 aa. Weakly similar to a hypothetical protein located on the Agrobacterium tumefaciens Ti-plasmid TR:BAA87720 (EMBL:AB016260) TiORF95 (336 aa), fasta scores opt: 464 z-score: 513.2 E(): 3.7e-21 29.8% identity in 329 aa overlap and to TR:CAC46423 (EMBL:AL591788) Rhizobium meliloti hypothetical transcription regulator protein SMC00163, 340 aa; fasta scores: opt: 1133 Z-score: 1207.2 E(): 1.3e-59; 52.959% identity in 338 aa overlap. Contains a putative helix-turn-helix motif situated between residues 5..26 (+5.89 SD). (348 aa) |
| | SCO6950 | Conserved hypothetical protein SC6F7.03; SC6F7.03, unknown, len: 467 aa. Weakly similar to several including: Streptomyces coelicolor TR:Q9X7U7(EMBL:AL049863) putative regulatory protein, SC5H1.40C (502 aa), fasta scores opt: 315 z-score: 356.4 E(): 2.1e-12 26.4% identity in 488 aa overlap. (467 aa) |
| | SCO6770 | SC6A5.19, probable DNA-binding protein, len: 204 aa; similar to several of undefined function eg. TR:O86784 (EMBL:AL031317) hypothetical protein from Streptomyces coelicolor (201 aa) fasta scores; opt: 297, z-score: 356.2, E(): 1.5e-12, (34.9% identity in 212 aa overlap). Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. (204 aa) |
| | SCO6713 | SC4C6.23, probable lacI-family transcriptional regulator, len: 352 aa; similar to many e.g. TR:O87590 (EMBL:AF086819), CelR, Thermomonospora fusca transcriptional regulator of cellulase genes (340 aa), fasta scores; opt: 991 z-score: 1119.2 E(): 0, 51.9% identity in 324 aa overlap. Similar to others from S. coelicolor e.g. TR:O86795 (EMBL:AL031317) S. coelicolor putative transcriptional regulator (355 aa) (36.3% identity in 342 aa overlap). Contains Pfam matches to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family and to entry PF00356 lacI, Bacterial regulator [...] (352 aa) |
| | SCO6236 | SCAH10.01c, possible DNA-binding protein, len: >270 aa; similar to TR:Q9Z543 (EMBL:AL035212) Streptomyces coelicolor putative binding protein, SC9B2.16c, len: 303 aa; fasta scores: opt: 466 z-score: 574.2 E(): 1.3e-24; 34.1% identity in 252 aa overlap. Contains a possible helix-turn-helix motif between residues 612..677 (+3.39 SD); SC2H4.18c, unknown, partial CDS, len: >55 aa; some similarity to the C-terminus of S. coelicolor hypothetical protein SC4G2.03, fasta scores; (E(): 0.018, 32.7% identity in 52 aa overlap). (291 aa) |
| | SCO6299 | SCIF3.01c, probable tetR-family transcriptional regulator, len: >248 aa; similar to TR:Q9XDV7 (EMBL:AB023642) Streptomyces griseus DNA-binding protein ORF2, 289 aa; fasta scores: opt: 847 z-score: 994.6 E(): 0; 65.3% identity in 245 aa overlap. Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family and possible helix-turn-helix motif at residues 28..49 (+3.30 SD); SCBAC8D1.12c, possible DNA-binding protein (fragment), len: >72 aa; similar to TR:Q9XDV7 (EMBL:AB023642) Streptomyces griseus DNA-binding protein ORF2, 289 aa; fasta scores: opt: 247 Z-score: 31 [...] (285 aa) |
| | SCO6349 | SC3A7.17, probable transcriptional regulator, len: 361 aa; similar to many of the lacI family e.g. LACI_ECOLI lactose operon repressor (360 aa), fasta scores; opt: 518 z-score: 705.7 E(): 4.6e-32, 33.6% identity in 339 aa overlap. Contains helix-turn-helix motif from aa 27-48 (Score 1760, +5.18 SD), and Pfam matches to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, score 35.20, E-value 1.9e-08 and to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, score 78.80, E-value 1.1e-19. (361 aa) |
| | SCO6410 | SC3C8.29, possible DNA-binding protein, len: 83 aa; contains probable helix-turn-helix motif at aa 29 to 50 (Score 1589, +4.60 SD)). (83 aa) |
| | SCO6537 | SC5C7.22c, unknown, len: 287 aa; similar to S. coelicolor hypothetical protein SC4G2.03 (E(): 2.2e-08, 29.2% identity in 257 aa overlap). Contains possible helix-turn-helix motif at aa 29-50 (Score 1251, +3.45 SD). (287 aa) |
| | SCO6539 | SC5C7.24c, hypothetical protein, len: 272 aa; similar to TR:Q985F1 (EMBL:AP003012) Rhizobium loti (Mesorhizobium loti) MLL7704 protein, 270 aa; fasta scores: opt: 786 Z-score: 877.1 E(): 3.2e-41; 48.638% identity in 257 aa overlap. (272 aa) |
| | SCO6598 | SC8A6.19, probable transcriptional regulator, len: 246 aa; similar to many members of the lacI family, e.g. CCP A_BACSU glucose-resistance amylase regulator (334 aa), fast a scores; opt: 313 z-score: 569.6 E(): 1.7e-24, 31.2% identity in 317 aa overlap. Contains PS00356 Bacterial regulatory proteins, lacI family signature, helix-tur-helix motif at aa 7-28 (Score 2389, +7.32 SD) and Pfam matches to entry P F00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, score 86.50, E-value 5.3e-22 and Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, sc [...] (346 aa) |
| | SCO6629 | SC4G2.03, hypothetical protein, len: 277 aa; similar to TR:Q9F345 (EMBL:AL391751) Streptomyces coelicolor hypothetical protein SC9E12.10c, 287 aa; fasta scores: opt: 769 Z-score: 890.8 E(): 5.5e-42; 48.736% identity in 277 aa overlap. (277 aa) |
| | SCO6675 | SC5A7.25c, possible DNA-binding protein, len: 218 aa. Contains probable helix-turn-helix motif from aa 92-113 (Score 1665, +4.86 SD). (218 aa) |
| | SCO0062 | SCJ4.43c, probable LacI family transcriptional regulator, len: 367 aa; similar to many transcriptional regulators e.g. SW:GALR_ECOLI galactose operon repressor (343 aa) fasta scores; opt: 549, z-score: 636.2, E(): 4.5e-28, (32.5% identity in 332 aa overlap). Contains Pfam matches to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family and entry PF00356 lacI, Bacterial regulatory proteins, lacI family. Contains possible helix-turn-helix motif (+3.86 SD) 26-47. (367 aa) |
| | SCO0110 | SCJ11.39c, possible DNA-binding protein, len: 279 aa; similar to TR:O86721 (EMBL:AL031515) hypothetical protein from Streptomyces coelicolor (272 aa) fasta scores; opt: 123, z-score: 148.4, E(): 0.66, (26.6% identity in 278 aa overlap). Contains possible helix-turn-helix motif 40-61 aa (+3.21 SD). (279 aa) |
| | SCO0148 | SCJ33.12, possible transcriptional regulatory protein, len: 81 aa. Highly similar to Bacillus subtilis TR:O31834 (EMBL:Z99114) YozG protein (84 aa), fasta scores opt: 307 z-score: 443.1 E(): 2.6e-17 61.8% identity in 68 aa overlap. Contains a Pfam match to entry PF01381 HTH_3, Helix-turn-helix which lies between residues 17..38 (+3.45 SD). (81 aa) |
| | SCO0160 | SCJ1.09c, possible DNA-binding protein, len: 195 aa, similarity to Mycobacterium tuberculosis TR:O53625 (EMBL; AL021428) hypothetical 16.6 KD protein (152 aa), fasta scores opt: 182 z-score: 220.8 E(): 6.1e-05 34.2% identity in 155 aa overlap and Mycobacterium tuberculosis TR:O05803 (EMBL; Z95150) hypothetical 12.3 KD protein (110 aa), fasta scores opt: 142 z-score: 177.2 E(): 0.016 34.8% identity in 89 aa overlap. Contains a Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a possible helix-turn-helix motif at residues 34..55 (+3.91 SD). (233 aa) |
| | mmyB | SCP1.230, mmyB, possible DNA-binding protein, len: 313aa; previously sequenced and annotated as TR:Q9JN77 (EMBL:AJ276673). Similar to many from Streptomyces coelicolor eg. TR:Q9RDF4 (EMBL:AL136503) putative DNA-binding protein (294 aa) fasta scores; opt: 670, z-score: 810.9, E(): 0, 43.1% identity in 255 aa overlap. Contains helix-turn-helix motif at residue 52-73 (Score 1329 (+3.71 SD)). Contains a TTA encoded leucine at residue 23, possible target for bldA regulation. (313 aa) |
| | SCP1.186 | SCP1.186, conserved hypothetical protein, len: 282aa; similar to other hypothetical proteins from streptomycetes eg. SCE6.06 (TR:Q9KZT2 EMBL:AL353832) from Streptomyces coelicolor (281 aa) fasta scores; opt: 882, z-score: 1083.5, E(): 0, 47.9% identity in 280 aa overlap. Note possible alternative downstream translational start site. (282 aa) |
| | SCP1.89c | Hypothetical protein; SCP1.89c, unknown, len: 389aa. (389 aa) |
| | SCO0174 | SCJ1.23c, possible DNA-binding protein, len: 323 aa. Similar in parts to many, e.g. Mycobacterium tuberculosis TR:O53625 (EMBL; AL021428) hypothetical 16.6 KD protein MTV030.24 (152 aa), fasta scores opt: 224 z-score: 258.5 E(): 4.9e-07 34.3% identity in 134 aa overlap and Mycobacterium tuberculosis SW:YU07_MYCTU (EMBL; Z77163) hypothetical 8.6 KD protein MTCY339.07C (80 aa), fasta scores opt: 182 z-score: 216.4 E(): 0.00011 42.3% identity in 71 aa overlap. Also similar to TR:Q9RJ05 (EMBL:AL109962) Streptomyces coelicolor possible DNA-binding protein SCJ1.09c, 233 aa; fasta scores: opt [...] (323 aa) |
| | SCO0233 | SCJ9A.12c, possible DNA-binding protein, len: 279 aa; N-terminal similar to TR:O86721 (EMBL:AL031515) hypothetical protein from Streptomyces coelicolor (272 aa) fasta scores; opt: 135, z-score: 165.1, E(): 0.079, (29.3% identity in 150 aa overlap). Contains possible helix-turn-helix motif (+3.31 SD) 37-58 aa. (279 aa) |
| | SCO0236 | SCJ9A.15c, possible DNA-binding protein, len: 290 aa; prediction based on GC Frameplot, Hidden Markov Model and amino acid usage. Similar to TR:CAC44562 (EMBL:AL596144) Streptomyces coelicolor putative DNA-binding protein SCBAC12C8.07c, 284 aa; fasta scores: opt: 636 Z-score: 730.2 E(): 4.9e-33; 43.060% identity in 281 aa overlap. Contains possible helix-turn-helix motif (+3.31 SD) residues 39-60. (290 aa) |
| | SCO0289 | SCF85.17c, probable transcriptional regulator, len: 342 aa. Similar to many e.g. Streptomyces lividans TR:Q9ZI18 (EMBL; AF043654) BxlR (338 aa), fasta scores opt: 753 z-score: 849.8 E(): 0 42.9% identity in 333 aa overlap and Streptomyces coelicolor TR:O86795 (EMBL; AL031317) putative transcriptional regulator SC6G4.32 (355 aa), fasta scores opt: 880 z-score: 991.6 E(): 0 47.5% identity in 339 aa overlap. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family and a [...] (342 aa) |
| | SCO0307 | SC5G9.16, possible DNA-binding protein, len: 295 aa; probable CDS suggested by GC frameplot and positional base preference. Similar to possible DNA-binding proteins from S. coelicolor e.g. SCJ9A.15c (cosmid SCJ9A), S. coelicolor possible DNA-binding protein (290 aa) (39.3% identity in 298 aa overlap). Contains probable helix-turn-helix motif at residues 35-56 (Score 1197, +3.26 SD). (295 aa) |
| | SCO0360 | SCF41.19c, probable DNA-binding, LacI family, regulator. len: 330 aa. Similar to Escherichia coli SW:GNTR_ECOLI (EMBL:D84362) gluconate utilization system GNT-I transcriptional repressor (331 aa), fasta scores opt: 674 z-score: 767.8 E(): 0 36.9% identity in 320 aa overlap. Contains a PS00356 Bacterial regulatory proteins, lacI family signature, a PS00237 G-protein coupled receptors signature, Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family and a Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, LacI family. Contains a possible h [...] (330 aa) |
| | SCO0376 | SCF62.02, possible transcriptional regulator, len: 200 aa. Similar to several proteins of undefined function from Streptomyces sp. e.g. Streptomyces coelicolor TR:CAB51134 (EMBL; Y18817) hypothetical 20.6 KD protein (190 aa), fasta scores opt: 352 z-score: 424.9 E(): 2.6e-16 37.0% identity in 189 aa overlap. Contains a Pfam match to entry PF01381 HTH_3, Helix-turn-helix between residues 29..50 (+5.17 SD). (200 aa) |
| | SCO0456 | SCF51A.34, possible LacI family transcriptional regulator, len: 347 aa. Highly similar to several including: Escherichia coli SW:CYTR_ECOLI (EMBL; X03683) transcriptional repressor CytR (341 aa), fasta scores opt: 504 z-score: 574.2 E(): 1.3e-24 31.6% identity in 339 aa overlap and Streptomyces coelicolor TR:O86598 (EMBL; AL031514) putative transcriptional regulator SC2H4.15 (342 aa), fasta scores opt: 807 z-score: 915.3 E(): 0 44.4% identity in 333 aa overlap. Contains a Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, a Pfam match to entry PF00532 Peripla [...] (347 aa) |
| | SCO0629 | SCF56.13c, possible transcriptional regulator, len: 369 aa; similar to TR:Q9Z509 (EMBL:AL035591) Streptomyces coelicolor putative transcriptional regulator (LacI family) SCC54.16, 368 aa; fasta scores: opt: 367 z-score: 401.8 E(): 5.4e-15; 33.2% identity in 352 aa overlap and to SW:CCPA_BACME (EMBL:L26052) Bacillus megaterium glucose-resistance amylase regulator CcpA, 332 aa; fasta scores: opt: 263 z-score: 290.5 E(): 8.4e-09; 26.3% identity in 339 aa overlap. Contains possible helix-turn-helix motif at residuees 25..46 (+5.42 SD). (369 aa) |
| | SCO0806 | SCF43.17c, possible LacI-family transcriptional regulatory protein, len: 341 aa. Similar to many regulators including: Escherichia coli SW:RBSR_ECOLI (EMBL:M13169) ribose operon repressor, RbsR (329 aa), fasta scores opt: 646 z-score: 726.9 E(): 0 35.9% identity in 334 aa overlap and Streptomyces coelicolor TR:Q9Z509 (EMBL:AL035591) putative transcriptional regulator (LacI family) SCC54.16 (368 aa), fasta scores opt: 659 z-score: 740.7 E(): 0 39.2% identity in 337 aa overlap. Contains a Pfam matches to entries PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family and Pf [...] (341 aa) |
| | SCO0886 | SCM1.19c, possible LacI-family transcriptional regulator, len: 344 aa. Similar to many including: Escherichia coli SW:RBSR_ECOLI (EMBL:M13169) ribose operon repressor (329 aa), fasta scores opt: 353 z-score: 387.9 E(): 2.9e-14 30.7% identity in 313 aa overlap. Also similar to several Streptomyces coelicolor putative LacI-family transcriptional regulators e.g. TR:CAB59495 (EMBL:AL132648) (350 aa), fasta scores opt: 377 z-score: 413.3 E(): 1.1e-15 33.9% identity in 345 aa overlap and TR:O87600 (EMBL:AF086832) (350 aa), fasta scores opt: 377 z-score: 413.3 E(): 1.1e-15 33.9% identity in 3 [...] (344 aa) |
| | SCO0891 | SCM1.24, possible DNA-binding protein, len: 279 aa. Highly similar to many Streptomyces coelicolor putative DNA-binding proteins e.g. TR:CAB53273 (EMBL:AL109972) SCJ9A.12C (279 aa), fasta scores opt: 564 z-score: 639.5 E(): 2.8e-28 37.2% identity in 269 aa overlap. Contains a Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a Prosite hit to PS00092 N-6 Adenine-specific DNA methylases signature. The putative helix-turn-helix motif is situated between residues 35..56 (+4.25 SD). (279 aa) |
| | SCO0953 | SCM11.08, probable lacI-family transcriptional regulator, len: 349 aa; similar to TR:O86598 (EMBL:AL031514) Streptomyces coelicolor putative transcriptional regulator, SC2H4.15, 342 aa; fasta scores opt: 949 z-score: 1067.0 E(): 0; 44.6% identity in 341 aa overlap and to SW:ASCG_ECOLI (EMBL:M73326) Escherichia coli cryptic asc operon repressor, 336 aa; fasta scores: opt: 409 z-score: 463.9 E(): 1.8e-18; 28.4% identity in 334 aa overlap. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family, score 37.90, E-value 3.1e-09 and PF00532 Peripla_BP_like, Pe [...] (349 aa) |
| | SCO0981 | SCBAC19F3.08c, possible DNA-binding protein, len: 489aa: similar to many eg. TR:AAK44705 (EMBL:AE006950) putative DNA-binding protein MT0481 from Mycobacterium tuberculosis (474 aa) fasta scores; opt: 1753, Z-score: 1963.4, 56.780% identity (58.009% ungapped) in 472 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop). (489 aa) |
| | SCO1066 | SCG22.12, probable lacI-family transcriptional regulator, len: 340 aa; similar to SW:CYTR_ECOLI (EMBL:X03683) Escherichia coli transcriptional repressor CytR, 341 aa; fasta scores: opt: 608 z-score: 692.2 E(): 4.4e-31; 34.2% identity in 339 aa overlap. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family and match to Prosite entry PS00356 Bacterial regulatory proteins, lacI family signature and possible helix-turn-helix motif at residues 4..25 (+6.04 SD). (340 aa) |
| | SCO1078 | SCG22.24, probable lacI-family transcriptional regulator, len: 349 aa; similar to TR:Q9S1T0 (EMBL:AL109950) Streptomyces coelicolor putative lacI-family transcriptional regulator SCJ4.43c, 367 aa; fasta scores: opt: 786 z-score: 894.0 E(): 0; 38.5% identity in 353 aa overlap and to SW:GALR_ECOLI (EMBL:V00280) Escherichia coli galactose operon repressor GalR, 343 aa; fasta scores: opt: 504 z-score: 575.9 E(): 1.3e-24; 31.3% identity in 336 aa overlap. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family and PF00532 Peripla_BP_like, Periplasmic bindin [...] (349 aa) |
| | SCP1.60 | SCP1.60, possible conserved DNA-binding protein, len: 290aa; similar to many from streptomycetes eg. TR:Q9RHR7 (EMBL:AB025200) ORF312 protein from plasmid pNO33 of Streptomyces albulus (285 aa) fasta scores; opt: 857, z-score: 1027.5, E(): 0, and TR:Q9KZY5 (EMBL:AL353815) putative DNA-binding protein from Streptomyces coelicolor (295 aa) fasta scores; opt: 706, z-score: 847.4, E(): 0, 40.8% identity in 282 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. (290 aa) |
| | SCO7817 | SC8E7.14, possible DNA-binding protein, len: 280 aa. Highly similar to many other putative DNA-binding proteins e.g. Streptomyces coelicolor TR:Q9S1Q8 (EMBL:AL109972) SCJ9A.12C (279 aa), fasta scores opt: 946 z-score: 1117.2 E(): 0 54.1% identity in 268 aa overlap. Contains a putative helix-turn-helix motif situated between residues 131..153 (+3.68 SD). (280 aa) |
| | SCO7767 | SC5E9.15c, possible DNA-binding protein, len: 275 aa; similar to many e.g. TR:Q9RD19 (EMBL:AL133422) putative DNA-binding protein from Streptomyces coelicolor (279 aa) fasta scores; opt: 510, z-score: 601.1, E(): 5.1e-26, 36.4% identity in 275 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a possible helix-turn-helix motif at residues 40..61 (+3.20 SD). (275 aa) |
| | SCO7733 | SC8D11.24, possible transcriptional regulatory protein, len: 739 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. Also contains a possible helix-turn-helix motif at residues 40..61 (+4.44 SD). (739 aa) |
| | SCO1186 | SCG11A.17, probable lacI-family transcriptional regulator, len: 341 aa; similar to TR:CAB46346 (EMBL:AJ009798) Streptomyces reticuli regulatory protein CebR, 350 aa; fasta scores: opt: 1241 z-score: 1440.4 E(): 0; 57.9% identity in 347 aa overlap and to SW:PURR_ECOLI (EMBL:J04212) Escherichia coli purine nucleotide synthesis repressor PurR, 340 aa; fasta scores: opt: 587 z-score: 684.5 E(): 9.5e-31; 35.7% identity in 336 aa overlap and to Streptomyces coelicolor SC4G6.23; fasta scores: opt: 989 z-score: 952.6 E(): 0; 53.8% identity in 316 aa overlap. Contains matches to Pfam entries PF [...] (341 aa) |
| | SCO1200 | SCG11A.31c, probable regulatory protein, len 191 aa; similar to TR:Q54855 (EMBL:X61931) Streptomyces purpurascens ORF1, 90 aa; fasta scores: opt: 560 z-score: 686.7 E(): 7.2e-31; 85.6% identity in 90 aa overlap and to TR:CAB39703 (EMBL:AL049485) Streptomyces coelicolor putative DNA-binding protein SC6A5.19, 204 aa; fasta scores: opt: 382 z-score: 468.0 E(): 1.1e-18; 39.2% identity in 176 aa overlap and to Streptomyces coelicolor SC6G4.21, fasta scores: opt: 717 z-score: 721.2 E(): 8e-35; 60.0% identity in 190 aa overlap. Contains match to Pfam entry PF01381 HTH_3, Helix-turn-helix and [...] (191 aa) |
| | SCO1227 | 2SCG1.02c, possible DNA-binding protein, len: 489 aa; similar to TR:CAB89011 (EMBL:AL353870) Streptomyces coelicolor hypothetical 50.9 kD protein SC6F7.03, 467 aa; fasta scores: opt: 177 z-score: 183.6 E(): 0.0092; 26.7% identity in 476 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a possible helix-turn-helix motif at residues 44..65 (+3.67 SD). Also contains a TTA leucine codon (159), possible target for bldA regulation. (489 aa) |
| | SCO1242 | 2SCG1.17, probable DNA-binding protein, len: 286 aa; similar to TR:CAB8844 (EMBL:AL353815) Streptomyces coelicolor putative DNA-binding protein SCD6.19, 295 aa; fasta scores: opt: 626 z-score: 747.0 E(): 0; 40.0% identity in 280 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a possible helix-turn-helix motif at residues 25..46 (+4.46 SD). Also contains a TTA leucine codon (58), possible target for bldA regulation. (286 aa) |
| | SCO1312 | SCBAC36F5.23c, probable transcriptional regulatory protein, len: 201 aa; similar to TR:Q9I1G3 (EMBL:AE004657) Pseudomonas aeruginosa probable transcriptional regulator PA2312, 193 aa; fasta scores: opt: 339 Z-score: 397.1 bits: 80.3 E(): 1.6e-14; 35.519% identity in 183 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and two possible helix-turn-helix domains at residues 35..56 (+2.92 SD) and 64..85 (+4.24 SD). (201 aa) |
| | SCO1376 | SC10A9.18, probable lacI-family transcriptional regulatory protein, len: 356 aa; similar to SW:CELR_THEFU (EMBL:AF086819) Thermomonospora fusca transcription regulator CelR, 340 aa; fasta scores: opt: 681 z-score: 700.7 E(): 1.4e-31; 40.7% identity in 339 aa overlap and to TR:O86795 (EMBL:AL031317) Streptomyces coelicolor probable transcriptional regulator SC6G4.32, 355 aa; fasta scores: opt: 1196 z-score: 1059.6 E(): 0; 56.7% identity in 344 aa overlap. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family and PF00532 Peripla_BP_like, Periplasmic bi [...] (356 aa) |
| | SCO1489 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. (167 aa) |
| | SCO1619 | SCI41.02c, possible transcriptional regulatory protein, len: 189 aa; similarity with TR:O53759 (EMBL:AL021933) Mycobacterium tuberculosis putative regulatory protein (140 aa); fasta scores: opt: 164 z-score: 208.0 E(): 0.00032, 31.3% identity in 112 aa overlap. Contains Pfam match PF01381 HTH_3, Helix-turn-helix. Contains probable helix-turn-helix motif at aa 25-46 (Score 1293, +3.59 SD). (189 aa) |
| | SCO1642 | SCI41.25, putative LacI family regulator, len 336 aa. Identical to TR:O87600 (EMBL:AF086832) Streptomyces coelicolor ORF4 and similar to TR:AAD36030 (EMBL:AE001758) Thermotoga maritima TM0949 transcriptional regulator, LacI family, 332 aa; fasta scores: opt: 476 z-score: 517.4 E(): 1.9e-21; 29.5% identity in 339 aa overlap. Contains possible helix-turn-helix motif at aa 23-44.(Score 1430, +4.06 SD). (350 aa) |
| | SCO1956 | SCC54.16, probable transcriptional regulator (lacI family), len: 368 aa; similar to many lacI family transcriptional regulators e.g. SW:RBSR_ECOLI RbsR, ribose operon repressor from Escherichia coli (329 aa) fasta scores; opt: 611, z-score: 696.2, E(): 1.8e-31, (34.2% identity in 336 aa overlap). Contains PS00356 Bacterial regulatory proteins, lacI family signature and Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, score 102.80, E-value 6.7e-27. Also contains Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, score [...] (368 aa) |
| | SCO1979 | SC3C9.14c, probable DNA-binding protein, len: 286 aa; similar to many Streptomyces DNA-binding proteins e.g. TR:Q9F3E2 (EMBL:AL450289) Streptomyces coelicolor putative DNA-binding proteins SC2H2.13, 290 aa; fasta scores: opt: 1019 Z-score: 1178.0 bits: 225.9 E(): 5.2e-58; 55.000% identity in 280 aa overlap and TR:O86719 (EMBL:AL031515) SC5C7.22c, 287 aa; fasta scores: opt: 1360 Z-score: 1390.2 bits: 265.1 E(): 1e-71; 69.338% identity in 287 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a possible helix-turn-helix motif at residues 28..49 (+4.23 SD). (286 aa) |
| | SCO2232 | Maltose operon transcriptional repressor; Transcriptional repressor of the maltosaccharide utilization operon malEFG. (344 aa) |
| | SCO2246 | Conserved hypothetical protein SC1G2.08c; SC1G2.08c, unknown, len: 258 aa. Similar to several proteins of undefined function from Streptomyces coelicolor including: TR:O86676(EMBL:AL031371) SC4G2.03 (277 aa), fasta scores opt: 604 z-score: 734.8 E():0 46.3% identity in 229 aa overlap and TR:Q9X8M2(EMBL:AL049628) SCE94.16C (280 aa), fasta scores opt: 469 z-score: 572.0 E(): 1.8e-24 35.2% identity in 230 aa overlap. This gene is duplicated on this cosmid and shares 76.1 % identity, in 259 aa overlap, with the downstream gene, SC1G2.15c. (258 aa) |
| | SCO2253 | Conserved hypothetical protein SC1G2.15c; SC1G2.15c, unknown, len: 258 aa. Similar to several proteins of undefined function from Streptomyces coelicolor including: TR:O86676(EMBL:AL031371) SC4G2.03 (277 aa), fasta scores opt: 758 z-score: 919.8 E():0 46.7% identity in 276 aa overlap and TR:Q9X8M2(EMBL:AL049628) SCE94.16C (280 aa), fasta scores opt: 476 z-score: 580.1 E(): 6.2e-25 32.7% identity in 260 aa overlap. This gene is duplicated on this cosmid and shares 76.1 % identity, in 259 aa overlap, with the upstream gene, SC1G2.08c. (284 aa) |
| | SCO2381 | SC4A7.09, hypothetical protein, len: 278 aa; simialr to various hypothetical proteins, e.g. TR:Q9X8M2 (EMBL:AL049628) Streptomyces coelicolor hypothetical 31.5 kD protein SCE94.16c, 280 aa; fasta scores: opt: 1333 z-score: 1595.1 E(): 0; 76.4% identity in 271 aa overlap. (278 aa) |
| | SCO2501 | SCC121.04c, possible DNA-binding protein, len: 298 aa; similar to TR:CAB52924 (EMBL:AL109949) Streptomyces coelicolor putative DNA-binding protein SCJ11.39c, 279 aa; fasta scores: opt: 713 z-score: 847.3 E(): 0; 44.0% identity in 266 aa overlap and to TR:CAB53273 (EMBL:AL109972) Streptomyces coelicolor putative DNA-binding protein SCJ9A.12c, 279 aa; fasta scores: opt: 416 z-score: 497.4 E(): 2.6e-20; 35.1% identity in 276 aa overlap. (298 aa) |
| | SCO2513 | SCC121.16, hypothetical protein, len: 277 aa; similar to various hypothetical proteins, e.g. TR:Q9X8M2 (EMBL:AL049628) Streptomyces coelicolor hypothetical 31.5 kD protein SCE94.16c, 280 aa; fasta scores: opt: 538 z-score: 655.5 E(): 4.1e-29; 37.1% identity in 259 aa overlap. (277 aa) |
| | SCO2537 | SCC77.04c, possible DNA-binding protein, len: 294 aa. Highly similar to several other Streptomyces coelicolor proteins including: TR:CAB52924 (EMBL:AL109949) putative DNA-binding protein SCJ11.39C (279 aa), fasta scores opt: 575 z-score: 702.8 E(): 9.3e-32 41.2% identity in 257 aa overlap and TR:CAB55664 (EMBL:AL117385) hypothetical 32.2 KD protein SC5G9.16 (295 aa), fasta scores opt: 521 z-score: 637.0 E(): 4.3e-28 36.5% identity in 288 aa overlap. Contains a putative helix-turn-helix motif situated between residues 47..68 (+2.88 SD). (294 aa) |
| | SCO2745 | SCC57A.16, probable LacI-family transcriptional regulator, len: 347 aa. Highly similar to many other regulators including: Escherichia coli SW:CYTR_ECOLI (EMBL:X03683) transcriptional repressor CytR (341 aa), fasta scores opt: 714 z-score: 751.4 E(): 0 34.9% identity in 332 aa overlap and Streptomyces coelicolor TR:Q9Z509 (EMBL:AL035591) putative transcriptional regulator SCC54.16 (368 aa), fasta scores opt: 843 z-score: 885.1 E():0 43.4% identity in 348 aa overlap. Contains a Prosite hit to PS00356 Bacterial regulatory proteins, lacI family signature and Pfam hits to PF00356 lacI, Bac [...] (347 aa) |
| | SCO2753 | SCC57A.24, possible LacI-family transcriptional regulator, len: 348 aa. Similar to many other putative Streptomyces coelicolor LacI-family regulators including: TR:Q9X862 (EMBL:AL049661) SCE134.07 (353 aa), fasta scores opt: 489 z-score: 554.3 E(): 1.8e-23 33.8% identity in 358 aa overlap and TR:O86795 (EMBL:AL031317) SC6G4.32 (355 aa), fasta scores opt: 460 z-score: 521.7 E(): 1.2e-21 37.1% identity in 353 aa overlap. Contains a Prosite hit to PS00356 Bacterial regulatory proteins, lacI family signature and Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI fami [...] (348 aa) |
| | SCO2794 | 2SCC13.02c, lacI-family transcriptional regulatory protein, len: 351 aa; highly similar to TR:Q9X9R3 (EMBL:AJ009798) Streptomyces reticuli CebR protein, 350 aa; fasta scores: opt: 2011 z-score: 2174.4 E(): 0; 89.4% identity in 350 aa overlap and C-terminal region identical to TR:BAB03462 (EMBL:AB036424) Streptomyces coelicolor transcriptional regulator (fragment) ORF5-H, 193 aa. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family and PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family and match to Prosi [...] (351 aa) |
| | SCO2865 | Putative regulatory protein; SCE6.02, possible regulatory protein, len: 280 aa. Similar to several proteins of undefined function including: Streptomyces albulus TR:BAA89264 (EMBL:AB025200) hypothetical protein ORF312 (285 aa), fasta scores opt: 585 z-score: 728.2 E():0 38.2% identity in 280 aa overlap and Streptomyces coelicolor TR:Q9Z543 (EMBL:AL035212) putative DNA binding protein, SC9B2.16C (303 aa), fasta scores opt: 313 z-score: 391.9 E(): 2.1e-14 31.0% identity in 284 aa overlap. Also weakly similar to SCE6.06, also located on this cosmid, fasta scores opt: 269 z-score: 293.0 E( [...] (280 aa) |
| | SCO2869 | Putative regulatory protein; SCE6.06, possible regulatory protein, len: 281 aa. Similar to several proteins of undefined function e.g. Streptomyces albulus TR:BAA89264(EMBL: AB025200) plasmid pNO33 protein ORF312 (285 aa), fasta scores opt: 356 z-score: 441.0 E(): 3.9e-17 30.9% identity in 282 aa overlap. Also weakly similar to SCE6.02, also located on this cosmid, fasta scores opt: 269 z-score: 293.0 E(): 8.1e-11 27.5% identity in 265 aa overlap. Contains a putative helix-turn-helix motif situated between residues 27..48 (+4.07 SD). (281 aa) |
| | SCO3272 | SCE39.22c, possible DNA-binding protein, len: 122aa; some similarity to TR:O64356 (EMBL:AF064539) Gp48 protein from bacteriophage N15 (95 aa) fasta scores; opt: 114, z-score: 155.2, E(): 0.25, (36.6% identity in 71 aa overlap). Contains probable helix-turn-helix (+6.85 SD) 82-103aa. (122 aa) |
| | SCO3308 | SCE68.06c, probable DNA-binding protein, len: 464 aa; similar to TR:Q9AK04 (EMBL:AL512944) Streptomyces coelicolor hypothetical protein SC8D11.15c, 471 aa; fasta scores: opt: 428 Z-score: 331.6 E(): 7.7e-11; 40.377% identity in 478 aa overlap; probable CDS suggested by positional base preference, GC frame analysis and amino acid composition. Contains a hydrophobic, possible membrane-spanning region, followed by a low-complexity proline- and serine-rich region from aa 210 to 250 approx. Contains probable helix-turn-helix motif at aa 20-41 (Score 1605, +4.65 SD). (464 aa) |
| | SCO7724 | SC8D11.15c, hypothetical protein, len: 471 aa; similar to TR:Q9WX25 (EMBL:AL079345) Streptomyces coelicolor putative membrane protein SCE68.06c, 464 aa; fasta scores: opt: 428 z-score: 361.4 E(): 1.4e-12; 40.4% identity in 478 aa overlap. (471 aa) |
| | SCO7706 | SCBAC12C8.07c, putative DNA-binding protein, len: 284aa: similar to many from Streptomyces coelicolor eg. TR:Q9ADL0 (EMBL:AL451182) putative DNA-binding protein 2SCK31.04c (291 aa) fasta scores; opt: 731, Z-score: 816.6, 47.778% identity in 270 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. (284 aa) |
| | SCO7615 | SC2H2.13, possible DNA-binding protein, len: 290 aa; similar to many Streptomyces coelicolor putative DNA-binding proteins, e.g. TR:CAC01466 (EMBL:AL391014) putative DNA-binding protein 2SCG1.17, 286 aa; fasta scores: opt: 613 z-score: 722.6 E(): 1e-32; 41.8% identity in 261 aa overlap and TR:CAA20634 (EMBL:AL031515) hypothetical protein SC5C7.22c, 287 aa; fasta scores: opt: 917 z-score: 1027.9 E(): 0; 50.0% identity in 292 aa overlap. Contains possible helix-turn-helix motif at residues 33..54 (+4.70 SD). (290 aa) |
| | SCO7579 | SC5F1.33, possible DNA-binding protein, len: 291 aa; similar to TR:Q9KZY5 (EMBL:AL353815) Streptomyces coelicolor putative DNA-binding protein SCD6.19, 295 aa; fasta scores: opt: 643 z-score: 787.2 E(): 0; 37.0% identity in 281 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. Also contains possible helix-turn-helix motif at residues 31..52 (+6.28 SD). (291 aa) |
| | SCO7554 | SC5F1.08c, probable lacI-family transcriptional regulator, len: 337 aa; similar to TR:Q9X9R3 (EMBL:AJ009798) Streptomyces reticuli CebR protein, 350 aa; fasta scores: opt: 1152 z-score: 1278.6 E(): 0; 54.6% identity in 339 aa overlap and to SW:CELR_THEFU (EMBL:AF086819) Thermomonospora fusca transcription regulator CelR, 340 aa; fasta scores: opt: 1031 z-score: 1145.4 E(): 0; 52.1% identity in 340 aa overlap. Also similar to TR:CAC10103 (EMBL:AL442165) Streptomyces coelicolor lacI-family transcriptional regulatory protein CebR 2SCC13.02c, 351 aa; fasta scores: opt: 1082 z-score: 996.3 [...] (337 aa) |
| | SCO7502 | SCBAC17A6.35c, possible LacI-family transcriptional regulator, len: 346 aa; similar to many e.g. SW:P46828 (CCPA_BACME) glucose-resistance amylase regulator CcpA from Bacillus megaterium (332 aa) fasta scores: opt: 528, Z-score: 565.6, 30.769% identity (31.902% ungapped) in 338 aa overlap and TR:Q9K433 (EMBL:AL359779) putative LacI-family transcriptional regulator from Streptomyces coelicolor (340 aa) fasta scores: opt: 993, Z-score: 1055.5, 49.422% identity (51.506% ungapped) in 346 aa overlap. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and suga [...] (346 aa) |
| | SCO7411 | SC6D11.07, possible LacI-family transcriptional regulator, len: 352 aa. Similar to several including Escherichia coli SW:LACI_ECOLI (EMBL:V00294) lactose operon repressor LacI (360 aa), fasta scores opt: 595 z-score: 670.0 E(): 6.7e-30 34.8% identity in 333 aa overlap and Streptomyces coelicolor TR:O86618 (EMBL:AL031155) putative transcriptional regulator SC3A7.17 (361 aa), fasta scores opt: 887 z-score: 995.3 E(): 0 46.0% identity in 350 aa overlap. Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family and PF00532 Peripla_BP_like, Periplasmic bindin [...] (352 aa) |
| | SCO7279 | SC5H1.13c, possible DNA-binding protein, len: 157 aa; contains region similar to TR:O33287 (EMBL:AL008967) Mycobacterium tuberculosis possible transcriptional regulator (112 aa), fasta scores; opt: 254 z-score: 260.9 E(): 3.3e-07, 50.0% identity in 94 aa overlap and TR:O86815 (EMBL:AL031031), SC7C7.10, S.coelicolor hypothetical protein (126 aa) (55.6% identity in 72 aa overlap). Possible DNA-binding function as it contains probable helix-turn-helix motif at aa 77-98 (Score 1354, +3.80 SD) and Pfam match to entry PF01381 HTH_3, Helix-turn-helix, score 41.30, E-value 2.2e-08. PQATR repea [...] (157 aa) |
| | SCO3365 | Conserved hypothetical protein; SCE94.16c, unknown, len: aa; similar to others from Streptomyces coelicolor eg. TR:E1370777 (EMBL:AL035212) possible DNA binding protein (303 aa) fasta scores; opt: 420, z-score: 512.3, E(): 3.2e-21, (32.5% identity in 265 aa overlap). (280 aa) |
| | SCO3421 | SCE9.28c, hypothetical protein, len: 274 aa; similar others from S.coelicolor e.g. TR:O86719 (EMBL:AL031515), SC5C7.22C, hypothetical protein (287 aa), fasta scores; opt: 727 z-score: 871.9 E(): 0, 44.7% identity in 273 aa overlap. (274 aa) |
| | SCO3485 | SCE65.21c, probable lacI-family transcriptional regulator, len: 349 aa; similar to TR:AAD42741 (EMBL:AF105219) Thermomonospora curvata putative regulatory protein AglR, 347 aa; fasta scores: opt: 563 z-score: 648.1 E(): 1e-28; 34.9% identity in 341 aa overlap and to SW:CYTR_ECOLI (EMBL:X03683) Escherichia coli, transcriptional repressor CytR 341 aa; fasta scores: opt: 552 z-score: 635.6 E(): 5e-28; 30.5% identity in 347 aa overlap. Contains matches to Pfam entries PF00356 lacI, Bacterial regulatory proteins, lacI family PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI. Co [...] (349 aa) |
| | SCO3506 | SCE134.07, possible lacI-family transcriptional regulator, len: 353 aa; similar to many e.g. SW:MALR_STRCO maltose operon transcriptional repressor MalR from Streptomyces coelicolor (344 aa) fasta scores; opt: 440, z-score: 508.9, E(): 4.9e-21, (32.4% identity in 352 aa overlap). Contains Pfam matches to entries PF00356 lacI, Bacterial regulatory proteins, lacI family and PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family. (353 aa) |
| | SCO3537 | SCE2.18c, possible DNA-binding protein, len: 390 aa; similar to TR:O53463 (EMBL:AL021899) putative regulator from Mycobacterium tuberculosis (346 aa) fasta scores; opt: 208, z-score: 251.9, E(): 1e-06, (32.8% identity in 302 aa overlap). Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. (390 aa) |
| | SCO3782 | SCH63.29c, possible regulatory protein, len: 449 aa; similar to TR:O86603 (EMBL:AL031155) Streptomyces coelicolor transcriptional regulator SC3A7.02c, 892 aa; blastp scores: Score = 148 (52.1 bits), Expect = 6.7e-07, P = 6.7e-07; Identities = 98/317 (30%), Positives = 130/317 (41%). Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and 4x matches to entry PF00515 TPR, TPR Domain. (449 aa) |
| | SCO3859 | SCH69.29, possible DNA-binding protein, len: 182 aa; highly similar to TR:CAA09629 (EMBL:AJ011500) hypothetical protein from granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22 (182 aa) fasta scores; opt: 1045, z-score: 1158.8, E(): 0, (90.1% identity in 182 aa overlap). Contains probable helix-turn-helix 38-59aa (+3.20 SD). (182 aa) |
| | SCO3943 | SCD78.10c, probable transcriptional regulator, len: 370 aa; identical to TR:G3644044 (EMBL:AF090833) putative transcriptional regulator (RstP) from Streptomyces coelicolor. Also similar to members of the lacI family of transcriptional regulators e.g. PURR_ECOLI ((EMBL:J04212)(fasta scores; opt: 345, z-score: 356.4, E(): 1.3e-12, 28.2% identity in 347 aa overlap) purine nucleotide synthesis repressor from Escherichia coli. Contains PS00356 Bacterial regulatory proteins, lacI family signature and Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, s [...] (370 aa) |
| | SCO4158 | SCD84.25c, probable LacI-family regulatory protein, len: 340 aa; similar to TR:CAB66206 (EMBL:AL136502) Streptomyces coelicolor putative LacI-family transcriptional regulatory protein SCF43.17c, 341 aa; fasta scores: opt: 572 z-score: 669.2 E(): 8e-30; 37.3% identity in 338 aa overlap and to SW:CCPA_BACME (EMBL:L26052) Bacillus megaterium glucose-resistance amylase regulator (catabolite control protein) CcpA, 332 aa; fasta scores: opt: 564 z-score: 660.1 E(): 2.6e-29; 34.3% identity in 309 aa overlap. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins an [...] (340 aa) |
| | SCO4176 | SCD66.13, conserved hypothetical protein, len: 280 aa; similar to TR:O86676 (EMBL:AL031371) Streptomyces coelicolor hypothetical 30.7 kD protein SC4G2.03, 277 aa; fasta scores: opt: 378 z-score: 466.2 E(): 1.7e-18; 31.7% identity in 262 aa overlap. (280 aa) |
| | SCO4198 | 2SCD46.12, probable DNA-binding protein, len: 141 aa; N-terminal region similar to many eg. TR:O53759 (EMBL:AL021933) putative regulatory protein from Mycobacterium tuberculosis (140 aa) fasta scores; opt: 412, z-score: 503.0, E(): 1.6e-20, 56.6% identity in 113 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and two helix-turn-helix motifs; (Score 979 (+2.52 SD)) at residue 51-72 and (Score 1963 (+5.87 SD)) at residue 22-43. (141 aa) |
| | SCO4301 | SCD95A.34c, possible DNA-binding protein, len: 279 aa; similar to various S. coelicolor hypothetical proteins, e.g. TR:CAB69734 (EMBL:AL137166) Streptomyces coelicolor hypothetical 30.4 kD protein SCC121.16, 277 aa; fasta scores: opt: 731 z-score: 897.3 E(): 0; 45.2% identity in 259 aa overlap and to TR:CAB88448 (EMBL:AL353815) Streptomyces coelicolor putative DNA-binding protein SCD6.19, 295 aa; fasta scores: opt: 388 z-score: 478.8 E(): 3.3e-19; 34.3% identity in 286 aa overlap. Contains TTA leucine codon, possible target for bldA regulation and a possible helix-turn-helix motif at r [...] (279 aa) |
| | SCO4441 | SCD6.19, possible DNA-binding protein, len: 295 aa; similar to many other S. coelicolor hypothetical proteins, e.g. TR:Q9X8K0 (EMBL:AL049841) Streptomyces coelicolor hypothetical 30.9 kD protein SCE9.28c, 274 aa; fasta scores: opt: 717 z-score: 834.5 E(): 0; 42.6% identity in 263 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and a possible helix-turn-helix motif at residues 37..58 (+5.84 SD). (295 aa) |
| | SCO4543 | 2SCD4.14c, hypothetical protein, len: 283 aa; identical to previously sequenced TR:Q9XD96 (EMBL:AF106004) Streptomyces coelicolor hypothetical 31.8 kDa protein, 283 aa. (283 aa) |
| | SCO4678 | SCD31.03, conserved hypothetical protein, len: 282 aa; similar to various hypothetical proteins, e.g. TR:CAB66187 (EMBL:AL136500) Streptomyces coelicolor hypothetical 31.7 kD protein SC1G2.15c, 284 aa; fasta scores: opt: 1359 z-score: 1611.1 E(): 0; 71.7% identity in 279 aa overlap. (282 aa) |
| | SCO4680 | SCD31.05c, possible DNA-binding protein, len: 296 aa; similar to TR:CAB53273 (EMBL:AL109972) Streptomyces coelicolor putative DNA binding protein SCJ9A.12c, 279 aa; fasta scores: opt: 782 z-score: 910.0 E(): 0; 46.1% identity in 271 aa overlap. (296 aa) |
| | SCO4743 | Conserved hypothetical protein; SC6G4.21, unknown, len: 201 aa; similar, in part, to a hypothetical protein from Streptomyces purpurascens TR:Q 54855 (EMBL:X61931) (90 aa), fasta scores; opt: 376 z-score : 584.3 E(): 2.8e-25, 58.5% identity in 94 aa overlap. Cont ains helix-turn-helix motif at aa 28-49 (Score 2176, +6.60 SD). (201 aa) |
| | SCO4754 | SC6G4.32, probable transcriptional regulator, len: 355 aa; similar to many members of the lacI family e.g. RBSR _ECOLI ribose operon repressor (329 aa), fasta scores; opt: 588 z-score: 718.4 E(): 9.4e-33, 34.8% identity in 305 aa overlap. Contains PS00356 Bacterial regulatory proteins, lacI family signature, helix-turn-helix motif at aa 20-41 (Score 2255, +6.87 SD) and Pfam matches to entry PF00356 lacI, Bacterial regulatory proteins, lacI family, score 36.90, E -value 6.1e-09 and to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and LacI family, score 127.80, E-va lue 2e-34. (355 aa) |
| | SCO4810 | SCD63A.21c, hypothetical protein, len: 342 aa; similar to TR:Q9Z9I2 (EMBL:AB024056) Streptomyces fradiae unknown protein, 306 aa; fasta scores: opt: 645 z-score: 632.8 E(): 8.7e-28; 44.5% identity in 281 aa overlap. (342 aa) |
| | SCO4944 | 2SCK31.04c, possible DNA-binding protein, len: 314 aa; similar to TR:Q9RI67 (EMBL:AL109949) Streptomyces coelicolor putative DNA-binding protein SCJ11.39c, 279 aa; fasta scores: opt: 544 z-score: 640.7 E(): 3.8e-28; 40.2% identity in 249 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and possible helix-turn-helix motif at residues 64..85 (+4.67 SD). (291 aa) |
| | SCO4998 | 2SCK36.21c, hypothetical protein, len: 283 aa; similar to TR:Q9XD96 (EMBL:AF106004) Streptomyces coelicolor hypothetical 31.8 kDa protein ORF3, 283 aa; fasta scores: opt: 815 Z-score: 959.3 bits: 185.4 E(): 8e-46; 45.230% identity in 283 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. (283 aa) |
| | SCO5095 | SCBAC28G1.21, ORF9, probable DNA-binding protein, len: 190 aa; identical to previously sequenced as TR:Q9X9V0 (EMBL:Y18817) Streptomyces coelicolor A3(2) hypothetical 20.6 kDa protein ORF9, 190 aa and similar to TR:O86784 (EMBL:AL031317) Streptomyces coelicolor SC6G4.21, 202 aa; fasta scores: opt: 642 Z-score: 656.2 bits: 128.2 E(): 7.9e-31; 53.968% identity in 189 aa overlap. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix and possible helix-turn-helix motif at residues 25..46 (+6.01 SD). (190 aa) |
| | SCO5125 | SC9E12.10c, hypothetical protein, len: 287 aa; similar to TR:Q9RDR4 (EMBL:AL136500) Streptomyces coelicolor hypothetical 31.7 kDa protein SC1G2.15c, 284 aa; fasta scores: opt: 1240 z-score: 1466.1 E(): 0; 67.2% identity in 287 aa overlap. (287 aa) |
| | SCO5337 | Hypothetical protein SCBAC5H2.06c; SCBAC5H2.06c, unknown, len: 243 aa. (243 aa) |
