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SCO4603 SCO4603 SCO5966 SCO5966 SCO4855 SCO4855 SCO5135 SCO5135 SCO6559 SCO6559 SCO7110 SCO7110 SCO7572 SCO7572 SCO0816 SCO0816 SCO0922 SCO0922 SCO3673 SCO3673 SCO4570 SCO4570
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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SCO4603NADH dehydrogenase subunit NuoI2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (197 aa)
SCO5966SCBAC16H6.01c, possible oxidase, len: >1032aa: similar to many of undefined function eg. TR:Q9EZK2 (EMBL:AF289509) putative oxidase YdiJ-like protein from Pseudomonas putida (1006 aa) fasta scores; opt: 880, Z-score: 889.5, 27.930% identity (31.672% ungapped) in 1024 aa overlap and TR:Q9F2Y0 (EMBL:AL392149) putative oxidoreductase SCD19.22 from Streptomyces coelicolor (951 aa) fasta scores; opt: 622, Z-score: 628.7, 49.698% identity (53.813% ungapped) in 994 aa overlap. Contains Prosite match to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature; Pfam match to entry PF029 [...] (1047 aa)
SCO4855SC5G8.23c, dhsB, probable succinate dehydrogenase iron-sulfur subunit, len: 257aa; strongly similar to many eg. SW:P07014 (DHSB_ECOLI) succinate dehydrogenase iron-sulfur protein from Escherichia coli (238 aa) fasta scores; opt: 729, z-score: 839.1, E(): 0, 44.3% identity in 237 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains, Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and Prosite match to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature; Belongs to the succinate [...] (257 aa)
SCO5135Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (106 aa)
SCO6559SC4B5.09c, respiratory chain oxidoreductase, len: 286 aa; similar to the N-terminal region of many proteins involved in electron transfer e.g. TR:P77908 (EMBL:U73807) FdhA formate dehydrogenase alpha subunit from Moorella thermoacetica (893 aa), fasta scores; opt: 685, z-score: 791.8, E(): 0, (38.4% identity in 284 aa overlap). Contains PS00551 Prokaryotic molybdopterin oxidoreductases signature 1, PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature, PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature, Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and r [...] (286 aa)
SCO7110Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (129 aa)
SCO7572SC5F1.26, possible oxidoreductase, len: 998 aa; similar to TR:Q9KKW5 (EMBL:AE004425) Vibrio cholerae oxidoreductase/iron-sulfur cluster-binding protein VCA0985, 959 aa; fasta scores: opt: 1999 z-score: 2189.0 E(): 0; 35.3% identity in 966 aa overlap. Contains Pfam matches to entries PF01565 FAD_binding_4, FAD binding domain and PF00037 fer4, 4Fe-4S binding domain and matches to Prosite entries PS00422 Granins signature 1 and PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. (998 aa)
SCO0816SCF43A.06, conserved possible iron-sulfur protein, len: 492 aa; similar to several putative iron-sulfur proteins e.g. SW:YKGF_ECOLI (EMBL:AE000137) Escherichia coli hypothetical protein (475 aa), fasta scores; opt: 1148 z-score: 1249.5 E(): 0, 39.7% identity in 481 aa overlap, which contains 2 putative 4Fe-4S centres. Contains PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. (492 aa)
SCO0922SCM10.10c, probable reductase iron-sulfur protein, len: 248 aa; similar to SW:FRDB_MYCTU (EMBL:Z74020) Mycobacterium tuberculosis fumarate reductase iron-sulfur protein (EC 1.3.99.1) FrdB, 247 aa; fasta scores: opt: 288 z-score: 321.7 E(): 1.6e-10; 28.9% identity in 239 aa overlap. Contains Pfam matches to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains and entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and to Prosite entries PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature and PS00198 4Fe-4S ferredoxins, iron-sulfu [...] (248 aa)
SCO3673SCH35.51c, probable iron-sulphur-binding reductase, len: 433 aa; similar to many eg. TR:P96797 (EMBL:Y09870) heterodisulphide reductase from Methanosarcina barkeri (409 aa) fasta scores; opt: 427, z-score: 463.9, E(): 1.6e-18, (28.9% identity in 443 aa overlap). Contains 2 Pfam matches to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and 2 Prosite matches to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. Contains also possible hydrophobic membrane spanning regions. (760 aa)
SCO4570NuoI, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (211 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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