Your Input: | |||||
SCO3380 | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (265 aa) | ||||
SCO3093 | SCE41.02c, possible hydrolase, len: 313 aa; similar to N-terminal region of SW:GPPA_ECOLI (EMBL:M87049) Escherichia coli guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (EC 3.6.1.40) GppA, 494 aa; fasta scores: opt: 311 z-score: 357.2 E(): 2.2e-12; 28.4% identity in 310 aa overlap. (313 aa) | ||||
SCO2846 | SCE20.20c, possible transcriptional regulatory protein, len: 406 aa. Similar in parts to several proteins of the ROK (NagC/XylR) family including: Bacillus subtilis SW:GLK_BACSU (EMBL:D84432) glucokinase (EC 2.7.1.2) (glucose kinase) (321 aa), fasta scores opt: 320 z-score: 310.6 E(): 6.4e-10 34.1% identity in 164 aa overlap and Thermotoga maritima TR:Q9X1I0 (EMBL:AE001798) glucokinase (317 aa), fasta scores opt: 385 z-score: 370.1 E(): 3.1e-13 33.6% identity in 360 aa overlap. Contains a Prosite hits to PS01125 ROK family signature and PS01228 Hypothetical cof family signature 1. Also [...] (406 aa) | ||||
SCO2662 | SC6D10.05, possible kinase, len: 305 aa; similar to TR:CAB61848 (EMBL:AJ242910) Homo sapiens N-acetylglucosamine kinase protein (EC 2.7.1.59), 344 aa; fasta scores: opt: 192 z-score: 223.6 E(): 4.8e-05; 24.5% identity in 253 aa overlap and to TR:CAB61849 (EMBL:AJ242909) Mus musculus N-acetylglucosamine kinase protein (EC 2.7.1.59), 343 aa; fasta scores: opt: 180 z-score: 210.1 E(): 0.00027; 24.4% identity in 250 aa overlap. (305 aa) | ||||
SCO2657 | SC8E4A.27, possible ROK-family transcriptional regulatory protein, len: 409 aa; similar to TR:O69941 (EMBL:AL023862) Streptomyces coelicolor hypothetical ROK family protein (fragment) SC3F9.01, 403 aa; fasta scores: opt: 456 z-score: 480.7 E(): 2.3e-19; 30.8% identity in 396 aa overlap and to SW:XYLR_CALSR (EMBL:L18965) Caldicellulosiruptor sp. putative xylose repressor XylR, 399 aa; fasta scores: opt: 381 z-score: 402.9 E(): 5e-15; 25.2% identity in 361 aa overlap. Contains Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family and Pfam match to entry PF00480 ROK, [...] (409 aa) | ||||
SCO2611 | SCC88.22c mreB, rod shape-determining protein, len: 343 aa; identical to previously sequenced TR:O33619 (EMBL:Y14206) Streptomyces coelicolor MreB protein, 342 aa and similar to SW:MREB_BACSU (EMBL:M95582) Bacillus subtilis rod shape-determining protein MreB, 337 aa; fasta scores: opt: 1346 z-score: 1516.0 E(): 0; 63.0% identity in 330 aa overlap. (343 aa) | ||||
SCO2462 | SC7A8.01, probable sugar kinase (fragment), len: >434 aa; similar to TR:CAB61582 (EMBL:AL133210) Streptomyces coelicolor xylulose kinase (fragment) XylB, 432 aa; fasta scores: opt: 822 z-score: 871.9 E(): 0; 38.8% identity in 418 aa overlap and to SW:XYLB_STRRU (EMBL:M73789) Streptomyces rubiginosus xylulose kinase (EC 2.7.1.17) XylB, 481 aa; fasta scores: opt: 814 z-score: 862.8 E(): 0; 39.5% identity in 423 aa overlap. Contains Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases and PS00445 FGGY family of carbohydrate kinases signature 2; SCC24.33, probable sugar ki [...] (482 aa) | ||||
SCO2451 | SCC24.22, probable rod shape-determining protein, len: 360 aa; similar to SW:MREB_BACSU (EMBL:M95582) Bacillus subtilis rod-shape determining protein MreB, 337 aa; fasta scores: opt: 740 z-score: 810.4 E(): 0; 34.8% identity in 322 aa overlap and to TR:CAB75392 (EMBL:AL139298) Streptomyces coelicolor rod shape-determining protein MreB, 343 aa; fasta scores: opt: 868 z-score: 835.5 E(): 0; 43.1% identity in 320 aa overlap. (360 aa) | ||||
SCO2126 | Glucokinase; Required for glucose repression of many different genes; Belongs to the ROK (NagC/XylR) family. (317 aa) | ||||
SCO1660 | Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (512 aa) | ||||
SCO1447 | SCL6.04c, possible ROK-family transcriptional regulatory protein, len: 399 aa; similar to TR:CAB71832 (EMBL:AL138662) Streptomyces coelicolor putative ROK-family regulatory protein SC8E4A.27, 409 aa; fasta scores: opt: 938 z-score: 965.1 E(): 0; 42.5% identity in 398 aa overlap and to SW:XYLR_ANATH (EMBL:Z69782) Anaerocellum thermophilum xylose repressor XylR, 399 aa; fasta scores: opt: 327 z-score: 341.8 E(): 1.3e-1; 22.2% identity in 397 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and possible helix-turn-helix motif at residues 26..47 (+2.84 SD). (399 aa) | ||||
SCO1261 | 2SCG18.08, probable transcriptional regulatory protein, len: 384 aa; similar to TR:Q9S2D8 (EMBL:AL110470) Streptomyces coelicolor putative transcriptional repressor protein SCF85.03, 385 aa; fasta scores: opt: 980 z-score: 1062.5 E(): 0; 44.2% identity in 380 aa overlap and to SW:XYLR_ANATH (EMBL:Z69782) Anaerocellum thermophilum xylose repressor XylR, 399 aa; fasta scores: opt: 376 z-score: 411.5 E(): 1.9e-15; 25.4% identity in 394 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and possible helix-turn-helix motif at residues 30..51 (+2.57 SD). (384 aa) | ||||
SCO1171 | SCG11A.02, possible xylose repressor, len: 402 aa; similar to SW:XYLR_BACSU (EMBL:M27248) Bacillus subtilis xylose repressor xylR, 384 aa; fasta scores: opt: 612 z-score: 642.4 E(): 2.1e-28; 29.4% identity in 381 aa overlap. Contains match to Pfam entry PF00480 ROK, ROK family and a possible helix-turn-helix motif at residues 43..64 (+3.15 SD). (402 aa) | ||||
SCO1170 | Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family. (481 aa) | ||||
SCO1115 | 2SCG38.08, hypothetical protein, len: 332 aa; similar to TR:O50524 (EMBL:AL009204) Streptomyces coelicolor hypothetical 34.4 kDa protein SC9B10.17, 330 aa; fasta scores: opt: 263 z-score: 269.2 E(): 1.5e-07; 29.2% identity in 329 aa overlap and to TR:Q9EWI7 (EMBL:AL450223) Streptomyces coelicolor hypothetical protein SC7H9.09c, 332 aa; fasta scores: opt: 619 Z-score: 612.5 E(): 1.7e-26; 45.289% identity in 329 aa overlap. (332 aa) | ||||
SCO1077 | SCG22.23c, probable sugar kinase, len: 317 aa; similar to SW:GLK_BACSU (EMBL:D84432) Bacillus subtilis glucokinase (EC 2.7.1.2) GlcK, 321 aa; fasta scores: opt: 495 z-score: 504.0 E(): 1.3e-20; 31.4% identity in 312 aa overlap. Contains match to Prosite entry PS01125 ROK family signature. (317 aa) | ||||
SCO1060 | SCG22.06, probable transcriptional repressor, len: 413 aa; similar to TR:O05180 (EMBL:Z71474) Bacillus megaterium Xyl repressor XylR, 388 aa; fasta scores: opt: 382 z-score: 417.8 E(): 8.5e-16; 31.3% identity in 386 aa overlap and to TR:CAB61583 (EMBL:AL133210) Streptomyces coelicolor possible xylose repressor SCF37.02, 402 aa; fasta scores: opt: 586 z-score: 523.0 E(): 1.5e-23; 48.0% identity in 396 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and a possible helix-turn-helix motif at residues 35..56 (+3.03 SD). (413 aa) | ||||
SCO1039 | SCG20A.19c, possible ROK family regulatory protein, len: 412 aa; similar to TR:O50502 (EMBL:AL009199) Streptomyces coelicolor probable transcriptional repressor protein SC7B7.05, 403 aa; fasta scores: opt: 456 z-score: 485.8 E(): 1.4e-19; 27.7% identity in 390 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family. (412 aa) | ||||
SCO0814 | SCF43A.04, probable rhamnose kinase, len: 484 aa; similar to rhamnose kinases e.g. SW:RHAB_ECOLI (EMBL:L19201), rhaB, Escherichia coli rhamnulokinase (489 aa), fasta scores; opt: 1136 z-score: 1280.7 E(): 0, 41.5% identity in 468 aa overlap. Also similar to many other carbohydrate kinases e.g. SW:FUCK_ECOLI (EMBL:X15025), fucK, Escherichia coli L-fuculokinase (482 aa) (27.7% identity in 411 aa overlap). Contains Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases. (484 aa) | ||||
SCO0794 | SCF43.05c, possible ROK family transcriptional regulator, len: 429 aa. Similar to Anaerocellum thermophilum SW:XYLR_ANATH (EMBL:Z69782) xylose repressor (399 aa), fasta scores opt: 519 z-score: 575.9 E(): 1.1e-24 28.1% identity in 402 aa overlap. Also highly similar to Streptomyces coelicolor TR:O87855(EMBL:AL031013) putative transcriptional regulator SC8A6.21c (441 aa), fasta scores opt: 2034 z-score: 2241.7 E():0 71.4% identity in 434 aa overlap. Contains a Pfam match to entry PF00480 ROK, ROK family and a putative helix-turn-helix motif situated between residues 30..51 (+3.09 SD). (429 aa) | ||||
SCO0757 | SCF81.16, possible phosphatase, len: 336 aa; low similarity to SW:PPX_ECOLI (EMBL:L06129) Escherichia coli exopolyphosphatase (EC 3.6.1.11) (metaphosphatase) Ppx, 512 aa; fasta scores: opt: 251 z-score: 287.5 E(): 1.2e-08; 24.8% identity in 303 aa overlap; Belongs to the GppA/Ppx family. (336 aa) | ||||
SCO0734 | 3SC5B7.12c, probable transcriptional repressor, len: 424 aa; similar to SW:MLC_ECOLI (EMBL:D32222) Escherichia coli transcriptional regulator Mlc protein, 406 aa; fasta scores: opt: 387 z-score: 414.7 E(): 1.4e-15; 24.1% identity in 344 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and possible helix-turn-helix motif at residues 64..85 (+6.19 SD). (424 aa) | ||||
SCO0627 | SCF56.11c, possible ATP utilising protein, len: 709 aa; low similarities to TR:O34180 (EMBL:U95372) Halobacterium volcanii hydantoinase, 514 aa; fasta scores: opt: 462 z-score: 480.2 E(): 2.3e-19; 28.9% identity in 575 aa overlap and to SW:OPLA_RAT (EMBL:U70825) Rattus norvegicus 5-oxoprolinase (EC 3.5.2.9), 1288 aa; fasta scores: opt: 255 z-score: 261.5 E(): 3.5e-07; 26.9% identity in 547 aa overlap. Contains match to Prosite entry PS00107 Protein kinases ATP-binding region signature. (709 aa) | ||||
SCO0509 | Glycerol kinase 2 (ATP:glycerol 3-phosphotransferase) (EC 2.7.1.30); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (507 aa) | ||||
SCO0275 | SCF85.03, possible transcriptional repressor protein, len: 385 aa. Low similarity to many repressor proteins e.g. Anaerocellum thermophilum SW:XYLR_ANATH (EMBL; Z69782)xylose repressor (399 aa), fasta scores opt: 325 z-score: 375.7 E(): 1.4e-13 23.3% identity in 395 aa overlap and Streptomyces coelicolor TR:O50502 (EMBL; AL009199) probable transcriptional repressor protein SC7B7.05 (403 aa), fasta scores opt: 402 z-score: 463.7 E(): 1.8e-18 29.7% identity in 404 aa overlap. Contains a Pfam match to entry PF00480 ROK, ROK family and has a possible helix turn helix motif between aa 30..51. (385 aa) | ||||
SCO0063 | SCJ4.44c, possible glucokinase, len: 311 aa; similar to many eg. SW:GLK_STRCO glucokinase from Streptomyces coelicolor (317 aa) fasta scores; opt: 175, z-score: 195.7, E(): 0.0015, (28.2% identity in 326 aa overlap). Contains Pfam match to entry PF00480 ROK, ROK family. (311 aa) | ||||
SCO6180 | Putative transferase; SC2G5.01, partial CDS, possible transferase, len:>187aa; constitutes the C-terminal end of SC6C5.16 (EMBL:AL034 492) from Streptomyces coelicolor. Similar to the C-terminal region of many egs. SW:CMCH_NOCLA3'-hydroxymethylcephem-O- carbamoyltransferase, a protein involved in cephamycin synthesis in Nocardia lactamdurans(520 aa) fasta scores; opt : 373, z-score: 451.4, E():7.4e-18, (40.1% identity in 167 aa overlap); SC6C5.16, partial CDS, unknown, len: 392aa; similar to many eg. SW:NOLO_RHISN nodulation associated protein NolNO from Rhizobium sp. (strain NGR234) ( [...] (546 aa) | ||||
SCO6260 | SCAH10.25, possible sugar kinase, len: 382 aa; similar to SW:GLK_STRCO (EMBL:X65932) Streptomyces coelicolor glucokinase (EC 2.7.1.2) (glucose kinase) Glk, 317 aa; fasta scores: opt: 1022 z-score: 1142.9 E(): 0; 46.6% identity in 311 aa overlap and to TR:CAB51974 EMBL:SC6E10 Streptomyces coelicolor SC6E10.20c, 317 aa; fasta scores: opt: 1022 z-score: 1035.4 E(): 0; 46.6% identity in 311 aa overlap. Contains a match to Pfam entry PF00480 ROK, ROK family and Prosite entry PS01125 ROK family signature. (382 aa) | ||||
SCO6566 | Putative ROK family protein; SC3F9.01, unknown, partial CDS, len: >403 aa; similar to many members of the ROK (nagC/xylR) family e.g. NAGC_ECOLI N-acetylglucosamine repressor (406 aa), fasta scores; opt: 513 z-score: 578.8 E(): 5e-25, 28.6% identity in 388 aa overlap and GLK_STRCO glucokinase (EC 2.7.1.2) (glucose kinase) (317 aa), fasta scores; opt: 544 z-score: 570.9 E(): 1.4e-24, 34.4% identity in 317 aa overlap. Contains PS01125 ROK family signature and Pfam match to entry ROK PF00480, ROK family, score 164.11. Also similar to S. coelicolor SC7B7.05, probable transcriptional repres [...] (460 aa) | ||||
SCO6600 | SC8A6.21c, probable transcriptional regulator, len: 441 aa; some similarity to members of the ROK family e.g. XYLR_ANATH xylose repressor (399 aa), fasta scores; opt: 365 z-score: 361.7 E(): 6.6e-13, 27.2% identity in 397 aa over lap. Contains Pfam match to entry PF00480 ROK, ROK family, score 38.10, E-value 3e-10. (441 aa) | ||||
SCO7004 | SC8F11.30, probable carbohydrate kinase,len: 479 aa. Highly similar to many e.g. Bacillus subtilis SW:GLPK_BACSU(EMBL:M34393) glycerol kinase (EC 2.7.1.30), GlpK (496 aa), fasta scores opt: 688 z-score: 766.4 E():0 35.1% identity in 496 aa overlap. Contains a Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases. (479 aa) | ||||
SCO7486 | SCBAC17A6.19c, possible ROK-family transcriptional regulator, len: 405 aa; similar to many e.g. TR:P95610 (EMBL:X99622) putative regulator from Rhodococcus erythropolis (397 aa) fasta scores: opt: 548, Z-score: 588.4, 36.776% identity (38.220% ungapped) in 397 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and Prosite match to PS01125 ROK family signature. (405 aa) | ||||
SCO7543 | SC8G12.19, possible Crp-family transcriptional regulator, len: 424 aa. Similar to several including: Bacillus subtilis SW:XYLR_BACSU (EMBL:M27248) xylose repressor (384 aa), fasta scores opt: 339 z-score: 347.1 E(): 7.1e-12 23.3% identity in 390 aa overlap and Streptomyces coelicolor TR:O50502 (EMBL:AL009199) probable transcriptional repressor protein, SC7B7.05 (403 aa), fasta scores opt: 691 z-score: 697.8 E(): 2.1e-31 33.9% identity in 387 aa overlap. Contains a Prosite hit to PS01125 ROK family signature and Pfam hits to PF00480 ROK, ROK family and PF00325 crp, Bacterial regulatory [...] (424 aa) | ||||
SCO7568 | SC5F1.22c, possible regulatory protein, len: 319 aa; similar to TR:O50502 (EMBL:AL009199) Streptomyces coelicolor probable transcriptional repressor protein SC7B7.05, 403 aa; fasta scores: opt: 377 z-score: 404.3 E(): 5.5e-15; 29.3% identity in 290 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family. (319 aa) | ||||
SCO7595 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (391 aa) | ||||
SCO7597 | SC7H9.09c, hypothetical protein, len: 332 aa; similar to TR:Q9EX11 (EMBL:AL445503) Streptomyces coelicolor hypothetical 33.0 kDa protein 2SCG38.08, 332 aa; fasta scores: opt: 619 z-score: 588.5 E(): 3e-25; 45.3% identity in 329 aa overlap. High content in alanine amino acid residues. (332 aa) | ||||
SCO6166 | Hypothetical protein SC6C5.02; SC6C5.02, unknown, len: 272aa. (272 aa) | ||||
SCO6115 | SC9B2.02, possible ROK family transcriptional regulator, len: 407 aa; similar to many e.g. SW:XYLR_BACSU xylose repressor XylR from Bacillus subtilis (384 aa) fasta scores; opt: 470, z-score: 522.8, E(): 7.9e-22, (28.4% identity in 370 aa overlap). Contains Pfam match to entry PF00480 ROK, ROK family. Also contains a probable helix-turn-helix (+3.71 SD) at residues 32 to 53. (407 aa) | ||||
SCO6110 | SCBAC1A6.34c, probable sugar kinase, len: 308 aa; similar to SW:GLK_STRCO (EMBL:X65932) Streptomyces coelicolor glucokinase (EC 2.7.1.2) Glk or SC6E10.20c, 317 aa; fasta scores: opt: 391 z-score: 407.0 E(): 4.3e-15; 34.4% identity in 314 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and match to Prosite entry PS01125 ROK family signature. (308 aa) | ||||
SCO6008 | SC7B7.05, probable transcriptional repressor protein, len 403 aa; similar to many eg. XYLR_ANATH Q44406 xylose repressor from Anaerocellum thermophilum (399 aa), fasta scores; opt: 548 z-score: 767.3 E(): 0, 33.1% identity in 393 aa overlap. Contains PS01125 ROK family signature and helix-turn-helix motif at aa positions 29-50 (Score 2016, +6.05 SD). (403 aa) | ||||
SCO5850 | Conserved hypothetical protein SC9B10.17; SC9B10.17, unknown, len: 330 aa; similar to TR:Q97U07 (EMBL:AE006910) hypothetical protein from Sulfolobus solfataricus (298 aa) fasta scores; opt: 370, Z-score: 414.6, E(): 1.8e-15, 31.596% identity (34.520% ungapped) in 307 aa overlap. (330 aa) | ||||
SCO5424 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (407 aa) | ||||
SCO5059 | SCBAC20F6.02, ppgK, polyphosphate glucokinase, len: 246 aa; highly similar to SW:PPGK_MYCTU (EMBL:U44834) Mycobacterium tuberculosis polyphosphate glucokinase (EC 2.7.1.63) PpgK or RV2702 or MTCY05A6.23, 265 aa; fasta scores: opt: 912 Z-score: 1042.8 bits: 200.5 E(): 1.7e-50; 57.322% identity in 239 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family. (246 aa) | ||||
SCO4752 | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (374 aa) | ||||
SCO4750 | Conserved hypothetical protein; SC6G4.28, unknown, len: 217 aa; similar to hypothetical proteins from many organisms e.g. YEAZ_ECOLI (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some similarity to downstre am protein gcp (SC6G4.30; E(): 0.00023, 26.5% identity in 2 34 aa overlap). (217 aa) | ||||
SCO4285 | SCD95A.18, possible sugar kinase, len: 326 aa; similar to TR:CAB60179 (EMBL:AL132824) Streptomyces coelicolor putative sugar kinase SCAH10.25, 382 aa; fasta scores: opt: 449 z-score: 453.3 E(): 8.7e-18; 37.2% identity in 301 aa overlap. Contains Pfam match to entry PF00480 ROK, ROK family and 5x degenerate repeat: (S/A)AP. (326 aa) | ||||
SCO3671 | Heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. (618 aa) | ||||
SCO3348 | SCE7.15c, possible DNA-binding protein, len: 309 aa; similar to SW:YV22_MYCTU hypothetical protein from Mycobacterium tuberculosis (328 aa) fasta scores; opt: 991, z-score: 1143.8, E(): 0, (55.0% identity in 289 aa overlap) and similar to N-terminal region of SW:PPX_ECOLI (EMBL:L06129) Escherichia coli exopolyphosphatase Ppx, 512 aa; fasta scores: opt: 286 Z-score: 317.1 E(): 5e-10; 25.329% identity in 304 aa overlap. Contains possible helix-turn-helix motif (+3.03 SD) at 251..272 aa; Belongs to the GppA/Ppx family. (309 aa) |