STRINGSTRING
SCO5235 SCO5235 SCO7031 SCO7031 SCO6597 SCO6597 SCO0293 SCO0293 SCO0458 SCO0458 SCO2758 SCO2758 SCO6300 SCO6300 SCO5685 SCO5685 SCO6032 SCO6032
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO5235SC7E4.32, possible sugar hydrolase, len: 496 aa; similar to SW:HEXA_ALTSO (EMBL:D17399) Alteromonas sp. beta-hexosaminidase A precursor (EC 3.2.1.52) Cht60, 598 aa; fasta scores: opt: 486 z-score: 525.0 E(): 9e-22; 34.4% identity in 363 aa overlap and to TR O69862 (EMBL:AL023702;) Streptomyces coelicolor putative hydrolase SC1C3.20c, 506 aa; fasta scores: opt: 1849 z-score: 1988.9 E(): 0; 60.6% identity in 498 aa overlap. Contains Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. (496 aa)
SCO7031beta-D-xylosidase; SC1H10.20, beta-D-xylosidase, len: 797 aa. Highly similar to Streptomyces lividans TR:Q9ZI15 (EMBL:AF043654) beta-D-xylosidase, BxlA (861 aa), fasta scores opt: 4473 z-score: 4774.4 E(): 0 89.2% identity in 789 aa overlap. Also highly similar to Streptomyces coelicolor TR:CAB55650(EMBL:AL117385) putative beta-xylosidase, SC5G9.02 (796 aa), fasta scores opt: 4215 z-score: 4499.4 E(): 0 79.1% identity in 788 aa overlap. Contains a Pfam matches to entries PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain and Pfam match to entry PF01915 Glyco_hydro_3_C [...] (797 aa)
SCO6597SC8A6.18, probable beta-glucosidase, len: 859 aa; si milar to many e.g. BGLS_AGRTU beta-glucosidase (EC 3.2.1.21) (818 aa), fasta scores; opt: 810 z-score: 1139.9 E(): 0, 37.2% identity in 862 aa overlap. (859 aa)
SCO0293SC5G9.02, probable beta-xylosidase, len: 796 aa; similar to many xylosidases and glucosidases e.g. TR:Q9ZI15 (EMBL:AF043654), blxA, Streptomyces lividans beta-D-xylosidase (861 aa), fasta scores; opt: 3669 z-score: 3880.7 E(): 0, 71.3% identity in 791 aa overlap. Similar to others from S.coelicolor e.g. TR:O87852 (EMBL:AL031013) S.coelicolor probable beta-glucosidase (859 aa) (29.7% identity in 811 aa overlap). Contains 2 Pfam matches to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3. (796 aa)
SCO0458SCF51A.36, probable Beta-glucosidase (EC 3.2.1.21), len: 762 aa. Highly similar to many e.g. Escherichia coli SW:BGLX_ECOLI (EMBL; U15049) periplasmic Beta-glucosidase precursor (EC 3.2.1.21) (765 aa), fasta scores opt: 851 z-score: 896.9 E(): 0 32.2% identity in 773 aa overlap. Contains 2x Pfam matches to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3. (762 aa)
SCO2758SCC57A.29, nagA, beta-N-acetylglucosaminidase (putative secreted protein), len: 615 aa, Highly similar to Streptomyces thermoviolaceus TR:O82840 (EMBL:AB008771) beta-N-acetylglucosaminidase precursor (EC 3.2.1.30) (632 aa), fasta scores opt: 3169 z-score: 3414.1 E():0 80.0% identity in 614 aa overlap. Note the N-terminus of the S. coelicolor protein varies significantly from that of the S. thermoviolaceus protein. Contains a Prosite hit to PS00775 Glycosyl hydrolases family 3 active site and a Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3. Also contains a possi [...] (615 aa)
SCO6300SCIF3.02c, probable secreted hydrolase, len: 615 aa; similar to SW:HEXA_ALTSO (EMBL:D17399) Alteromonas sp. beta-hexosaminidase A precursor (EC 3.2.1.52) Cht60, 598 aa; fasta scores: opt: 565 z-score: 617.5 E(): 7.4e-27; 33.8% identity in 550 aa overlap and to TR:Q9RDG9 (EMBL:AL136519) Streptomyces coelicolor beta-N-acetylglucosaminidase NagA, 615 aa; fasta scores: opt: 2497 z-score: 2289.5 E(): 0; 65.6% identity in 605 aa overlap. Contains Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain and PF01915 Glyco_hydro_3_C, Glycosyl hydrolase family 3 C [...] (615 aa)
SCO5685SC5H4.09c, probable sugar hydrolase, len: 960 aa; similar to TR:Q59506 (EMBL:L06134) Microbispora bispora glucan-glucohydrolase (EC 3.2.1.74) (glucan 1,4-beta-glucosidase) (exo-1,4-beta-glucosidase) BglA, 986 aa; fasta scores: opt: 1257 z-score: 1346.1 E(): 0; 47.7% identity in 979 aa overlap. Contains Pfam matches to entries PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain and PF01915 Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain. (960 aa)
SCO6032SC1C3.20c, possible hydrolase, len: 506 aa; weakly similar to many e.g. HEXA_ALTSO beta-hexosaminidase a precursor (598 aa), fasta scores; opt: 463 z-score: 613.4 E(): 6.2e-27, 29.7% identity in 526 aa overlap. (506 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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